Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY t...
Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial
About this item
Full title
Author / Creator
Larson, Richard A. , Mandrekar, Sumithra J. , Huebner, Lucas J. , Sanford, Ben L. , Laumann, Kristina , Geyer, Susan , Bloomfield, Clara D. , Thiede, Christian , Prior, Thomas W. , Döhner, Konstanze , Marcucci, Guido , Voso, Maria Teresa , Klisovic, Rebecca B. , Galinsky, Ilene , Wei, Andrew H. , Sierra, Jorge , Sanz, Miguel A. , Brandwein, Joseph M. , de Witte, Theo , Niederwieser, Dietger , Appelbaum, Frederick R. , Medeiros, Bruno C. , Tallman, Martin S. , Krauter, Jürgen , Schlenk, Richard F. , Ganser, Arnold , Serve, Hubert , Ehninger, Gerhard , Amadori, Sergio , Gathmann, Insa , Döhner, Hartmut and Stone, Richard M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The prospective randomized, placebo-controlled CALGB 10603/RATIFY trial (Alliance) demonstrated a statistically significant overall survival benefit from the addition of midostaurin to standard frontline chemotherapy in a genotypically-defined subgroup of 717 patients with
FLT3
-mutant acute myeloid leukemia (AML). The risk of death was reduc...
Alternative Titles
Full title
Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial
Authors, Artists and Contributors
Author / Creator
Mandrekar, Sumithra J.
Huebner, Lucas J.
Sanford, Ben L.
Laumann, Kristina
Geyer, Susan
Bloomfield, Clara D.
Thiede, Christian
Prior, Thomas W.
Döhner, Konstanze
Marcucci, Guido
Voso, Maria Teresa
Klisovic, Rebecca B.
Galinsky, Ilene
Wei, Andrew H.
Sierra, Jorge
Sanz, Miguel A.
Brandwein, Joseph M.
de Witte, Theo
Niederwieser, Dietger
Appelbaum, Frederick R.
Medeiros, Bruno C.
Tallman, Martin S.
Krauter, Jürgen
Schlenk, Richard F.
Ganser, Arnold
Serve, Hubert
Ehninger, Gerhard
Amadori, Sergio
Gathmann, Insa
Döhner, Hartmut
Stone, Richard M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8591906
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8591906
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-021-01179-4