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68 results for Aziridines+-+pharmacology

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Select record 21
ArticlesPeer ReviewedFull Text
fully dissociated compound of plant origin for inflammatory gene repression
Author / Creator:Bosscher, K. de ; Berghe, W. vanden ; Beck, I.M.E ; Molle, W. van ; Hennuyer, N ; Hapgood, J ; Libert, C ; Staels, B ; Louw, A ; Haegeman, G
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (44), p.15827-15832
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Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer
Author / Creator:Phillips, Roger M. ; Loadman, Paul M. ; Reddy, Guru
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2019-06, Vol.83 (6), p.1183-1189
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Vaccination of koalas ( Phascolarctos cinereus) with a recombinant chlamydial major outer membrane protein adjuvanted with poly I:C, a host defense peptide and polyphosphazine, elicits strong and long...
Author / Creator:Khan, Shahneaz Ali ; Waugh, Courtney ; Rawlinson, Galit ; Brumm, Jacqui ; Nilsson, Karen ; Gerdts, Volker ; Potter, Andrew ; Polkinghorne, Adam ; Beagley, Kenneth ; Timms, Peter
Publisher:Kidlington: Elsevier Ltd
Journal title:Vaccine, 2014-10, Vol.32 (44), p.5781-5786
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Madurastatin B3, a rare aziridine derivative from actinomycete Nocardiopsis sp. LS150010 with potent anti-tuberculosis activity
Author / Creator:Zhang, Xinjun ; He, Hongtao ; Ma, Rong ; Ji, Zengchun ; Wei, Qi ; Dai, Huanqin ; Zhang, Lixin ; Song, Fuhang
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of industrial microbiology & biotechnology, 2017-05, Vol.44 (4-5), p.589-594
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Effects of Three Types of Inactivation Agents on the Antibody Response and Immune Protection of Inactivated IHNV Vaccine in Rainbow Trout
Author / Creator:Tang, Lijie ; Kang, Haiyan ; Duan, Kexin ; Guo, Mengting ; Lian, Gaihong ; Wu, Yang ; Li, Yijing ; Gao, Shuai ; Jiang, Yanping ; Yin, Jiyuan ; Liu, Min
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Viral immunology, 2016-09, Vol.29 (7), p.43-435
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Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents
Author / Creator:Giovine, Arianna ; Muraglia, Marilena ; Florio, Marco ; Rosato, Antonio ; Corbo, Filomena ; Franchini, Carlo ; Musio, Biagia ; Degennaro, Leonardo ; Luisi, Renzo
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2014-08, Vol.19 (8), p.11505-11519
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Compound A, a Dissociated Glucocorticoid Receptor Modulator, Inhibits T-bet (Th1) and Induces GATA-3 (Th2) Activity in Immune Cells
Author / Creator:Liberman, Ana C. ; Antunica-Noguerol, Maria ; Ferraz-de-Paula, Viviane ; Palermo-Neto, Joao ; Castro, Carla N. ; Druker, Jimena ; Holsboer, Florian ; Perone, Marcelo J. ; Gerlo, Sarah ; De Bosscher, Karolien ; Haegeman, Guy ; Arzt, Eduardo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e35155-e35155
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Genome shuffling and high-throughput screening of Brevibacterium flavum MDV1 for enhanced l-valine production
Author / Creator:Huang, Qin-Geng ; Zeng, Bang-Ding ; Liang, Ling ; Wu, Song-Gang ; Huang, Jian-Zhong
Publisher:Dordrecht: Springer Netherlands
Journal title:World journal of microbiology & biotechnology, 2018-08, Vol.34 (8), p.121-10, Article 121
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Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis
Author / Creator:Wüst, Simone ; Tischner, Denise ; John, Michael ; Tuckermann, Jan P. ; Menzfeld, Christiane ; Hanisch, Uwe-Karsten ; van den Brandt, Jens ; Lühder, Fred ; Reichardt, Holger M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-12, Vol.4 (12), p.e8202-e8202
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Select record 30
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Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo
Author / Creator:Theys, J ; Pennington, O ; Dubois, L ; Anlezark, G ; Vaughan, T ; Mengesha, A ; Landuyt, W ; Anné, J ; Burke, P J ; Dûrre, P ; Wouters, B G ; Minton, N P ; Lambin, P
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2006-11, Vol.95 (9), p.1212-1219
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Molecular modeling and structure-based drug discovery approach reveals protein kinases as off-targets for novel anticancer drug RH1
Author / Creator:Gupta, Pramodkumar P. ; Bastikar, Virupaksha A. ; Kuciauskas, Dalius ; Kothari, Shanker Lal ; Cicenas, Jonas ; Valius, Mindaugas
Publisher:New York: Springer US
Journal title:Medical oncology (Northwood, London, England), 2017-10, Vol.34 (10), p.176-176, Article 176
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Select record 32
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Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy
Author / Creator:Srivastava, Gunjan ; Somasundaram, Raj Thani ; Walfish, Paul G. ; Ralhan, Ranju
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-07, Vol.10 (7), p.e0133735
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Select record 33
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Cell-mediated immune response and cross-protective efficacy of binary ethylenimine-inactivated bluetongue virus serotype-1 vaccine in sheep
Author / Creator:Umeshappa, Channakeshava Sokke ; Singh, Karam Pal ; Pandey, Awadh Bihari ; Singh, Rabindra Prasad ; Nanjundappa, Roopa Hebbandi
Publisher:Kidlington: Elsevier Ltd
Journal title:Vaccine, 2010-03, Vol.28 (13), p.2522-2531
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Select record 34
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Combined antitumor activity of the nitroreductase/CB1954 suicide gene system and γ-rays in HeLa cells in vitro
Author / Creator:Teng, Geling ; Ju, Yuanrong ; Yang, Yepeng ; Hua, Hu ; Chi, Jingyu ; Mu, Xiuan
Publisher:Greece: D.A. Spandidos
Journal title:Molecular medicine reports, 2016-12, Vol.14 (6), p.5164-5170
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Select record 35
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Foot-and-mouth disease virus particles inactivated with binary ethylenimine are efficiently internalized into cultured cells
Author / Creator:Martín-Acebes, Miguel A ; Vázquez-Calvo, Ángela ; González-Magaldi, Mónica ; Sobrino, Francisco
Publisher:Kidlington: Elsevier Ltd
Journal title:Vaccine, 2011-12, Vol.29 (52), p.9655-9662
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Select record 36
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Anti-tumor activity and mechanism of action for a cyanoaziridine-derivative, AMP423
Author / Creator:Dorr, Robert T. ; Wisner, Lee ; Samulitis, Betty K. ; Landowski, Terry H. ; Remers, William A.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2012-04, Vol.69 (4), p.1039-1049
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Select record 37
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Nitroreductase-based GDEPT
Author / Creator:Denny, William
Publisher:Hilversum: Bentham Science Publishers Ltd
Journal title:Current pharmaceutical design, 2002-07, Vol.8 (15), p.1349-1361
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Select record 38
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2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT
Author / Creator:Helsby, N A ; Ferry, D M ; Patterson, A V ; Pullen, S M ; Wilson, W R
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2004-03, Vol.90 (5), p.1084-1092
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The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411(NTR)
Author / Creator:Singleton, D C ; Li, D ; Bai, S Y ; Syddall, S P ; Smaill, J B ; Shen, Y ; Denny, W A ; Wilson, W R ; Patterson, A V
Publisher:England
Journal title:Cancer gene therapy, 2007-12, Vol.14 (12), p.953-967
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Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase
Author / Creator:Bilsland, Alan E ; Anderson, Claire J ; Fletcher-Monaghan, Aileen J ; McGregor, Fiona ; Jeffry Evans, T R ; Ganly, Ian ; Knox, Richard J ; Plumb, Jane A ; Nicol Keith, W
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2003-01, Vol.22 (3), p.370-380
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Showing 21 to 40 of 68 results

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fully dissociated compound of plant origin for inflammatory gene repression

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Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer

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Vaccination of koalas ( Phascolarctos cinereus) with a recombinant chlamydial major outer membrane protein adjuvanted with poly I:C, a host defense peptide and polyphosphazine, elicits strong and long...

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Madurastatin B3, a rare aziridine derivative from actinomycete Nocardiopsis sp. LS150010 with potent anti-tuberculosis activity

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Effects of Three Types of Inactivation Agents on the Antibody Response and Immune Protection of Inactivated IHNV Vaccine in Rainbow Trout

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Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents

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Compound A, a Dissociated Glucocorticoid Receptor Modulator, Inhibits T-bet (Th1) and Induces GATA-3 (Th2) Activity in Immune Cells

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Genome shuffling and high-throughput screening of Brevibacterium flavum MDV1 for enhanced l-valine production

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Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis

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Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo

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Molecular modeling and structure-based drug discovery approach reveals protein kinases as off-targets for novel anticancer drug RH1

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Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy

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Cell-mediated immune response and cross-protective efficacy of binary ethylenimine-inactivated bluetongue virus serotype-1 vaccine in sheep

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Combined antitumor activity of the nitroreductase/CB1954 suicide gene system and γ-rays in HeLa cells in vitro

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Foot-and-mouth disease virus particles inactivated with binary ethylenimine are efficiently internalized into cultured cells

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Anti-tumor activity and mechanism of action for a cyanoaziridine-derivative, AMP423

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Nitroreductase-based GDEPT

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2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT

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The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411(NTR)

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Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase

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