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Select record 21
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Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells
Author / Creator:Juhl, Alice Dupont ; Heegaard, Christian W. ; Werner, Stephan ; Schneider, Gerd ; Krishnan, Kathiresan ; Covey, Douglas F. ; Wüstner, Daniel
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-04, Vol.11 (1), p.8927-8927, Article 8927
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Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model
Author / Creator:Salvatore, Sofia V. ; Ilagan, Ma. Xenia G. ; Shu, Hongjin ; Lambert, Peter M. ; Benz, Ann ; Qian, Mingxing ; Covey, Douglas F. ; Zorumski, Charles F. ; Mennerick, Steven
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-01, Vol.14 (1), p.1042-9, Article 1042
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Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling
Author / Creator:Nachtergaele, Sigrid ; Whalen, Daniel M ; Mydock, Laurel K ; Zhao, Zhonghua ; Malinauskas, Tomas ; Krishnan, Kathiresan ; Ingham, Philip W ; Covey, Douglas F ; Siebold, Christian ; Rohatgi, Rajat
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2013-10, Vol.2, p.e01340-e01340
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Enantioselective Protein-Sterol Interactions Mediate Regulation of Both Prokaryotic and Eukaryotic Inward Rectifier K+ Channels by Cholesterol
Author / Creator:D'Avanzo, Nazzareno ; Hyrc, Krzysztof ; Enkvetchakul, Decha ; Covey, Douglas F. ; Nichols, Colin G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-04, Vol.6 (4), p.e19393-e19393
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Anticonvulsant Medications Extend Worm Life-Span
Author / Creator:Evason, Kimberley ; Huang, Cheng ; Yamben, Idella ; Covey, Douglas F ; Kornfeld, Kerry
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2005-01, Vol.307 (5707), p.258-262
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The Mechanism of Enantioselective Neurosteroid Actions on GABAA Receptors
Author / Creator:Tateiwa, Hiroki ; Chintala, Satyanarayana M. ; Chen, Ziwei ; Wang, Lei ; Amtashar, Fatima ; Bracamontes, John ; Germann, Allison L. ; Pierce, Spencer R. ; Covey, Douglas F. ; Akk, Gustav ; Evers, Alex S.
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-02, Vol.13 (2), p.341
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Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice
Author / Creator:Latham, Janelle R. ; Pathirathna, Sriyani ; Jagodic, Miljen M. ; Joo Choe, Won ; Levin, Michaela E. ; Nelson, Michael T. ; Yong Lee, Woo ; Krishnan, Kathiresan ; Covey, Douglas F. ; Todorovic, Slobodan M. ; Jevtovic-Todorovic, Vesna
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-11, Vol.58 (11), p.2656-2665
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Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone
Author / Creator:Zampieri, Stefania ; Mellon, Synthia H. ; Butters, Terry D. ; Nevyjel, Marco ; Covey, Douglas F. ; Bembi, Bruno ; Dardis, Andrea
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of cellular and molecular medicine, 2009-09, Vol.13 (9b), p.3786-3796
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Pregnane X Receptor (PXR) Activation: A Mechanism for Neuroprotection in a Mouse Model of Niemann-Pick C Disease
Author / Creator:Langmade, S. Joshua ; Gale, Sarah E. ; Frolov, Andrey ; Mohri, Ikuko ; Suzuki, Kinuko ; Mellon, Synthia H. ; Walkley, Steven U. ; Covey, Douglas F. ; Schaffer, Jean E. ; Ory, Daniel S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-09, Vol.103 (37), p.13807-13812
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Cholesterol Tuning of BK Ethanol Response Is Enantioselective, and Is a Function of Accompanying Lipids
Author / Creator:Yuan, Chunbo ; Chen, Maohui ; Covey, Douglas F. ; Johnston, Linda J. ; Treistman, Steven N.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-11, Vol.6 (11), p.e27572-e27572
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A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons
Author / Creator:Chen, Daniel M. ; Ziolkowski, Luke ; Benz, Ann ; Qian, Mingxing ; Zorumski, Charles F. ; Covey, Douglas F. ; Mennerick, Steven
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2018-12, Vol.12, p.923-923
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Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels
Author / Creator:Tat, Quy L. ; Joksimovic, Srdjan M. ; Krishnan, Kathiresan ; Covey, Douglas F. ; Todorovic, Slobodan M. ; Jevtovic-Todorovic, Vesna
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-12, Vol.9 (12), p.2674
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5β-Dihydrosteroids: Formation and Properties
Author / Creator:Penning, Trevor M. ; Covey, Douglas F.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (16), p.8857
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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis
Author / Creator:Freitas, Florencio Porto ; Alborzinia, Hamed ; dos Santos, Ancély Ferreira ; Nepachalovich, Palina ; Pedrera, Lohans ; Zilka, Omkar ; Inague, Alex ; Klein, Corinna ; Aroua, Nesrine ; Kaushal, Kamini ; Kast, Bettina ; Lorenz, Svenja M. ; Kunz, Viktoria ; Nehring, Helene ; Xavier da Silva, Thamara N. ; Chen, Zhiyi ; Atici, Sena ; Doll, Sebastian G. ; Schaefer, Emily L. ; Ekpo, Ifedapo ; Schmitz, Werner ; Horling, Aline ; Imming, Peter ; Miyamoto, Sayuri ; Wehman, Ann M. ; Genaro-Mattos, Thiago C. ; Mirnics, Karoly ; Kumar, Lokender ; Klein-Seetharaman, Judith ; Meierjohann, Svenja ; Weigand, Isabel ; Kroiss, Matthias ; Bornkamm, Georg W. ; Gomes, Fernando ; Netto, Luis Eduardo Soares ; Sathian, Manjima B. ; Konrad, David B. ; Covey, Douglas F. ; Michalke, Bernhard ; Bommert, Kurt ; Bargou, Ralf C. ; Garcia-Saez, Ana ; Pratt, Derek A. ; Fedorova, Maria ; Trumpp, Andreas ; Conrad, Marcus ; Friedmann Angeli, José Pedro
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2024-02, Vol.626 (7998), p.401-410
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Effects of Natural and Enantiomeric Cholesterol on the Thermotropic Phase Behavior and Structure of Egg Sphingomyelin Bilayer Membranes
Author / Creator:Mannock, David A. ; McIntosh, Thomas J. ; Jiang, Xin ; Covey, Douglas F. ; McElhaney, Ronald N.
Publisher:United States: Elsevier Inc
Journal title:Biophysical journal, 2003-02, Vol.84 (2), p.1038-1046
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The Synthetic Enantiomer of Pregnenolone Sulfate is very Active on Memory in Rats and Mice, Even More so Than Its Physiological Neurosteroid Counterpart: Distinct Mechanisms?
Author / Creator:Akwa, Yvette ; Ladurelle, Nathalie ; Covey, Douglas F. ; Baulieu, Etienne-Emile
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.14033-14037
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The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism
Author / Creator:Rudolf, Amalie F. ; Kinnebrew, Maia ; Kowatsch, Christiane ; Ansell, T. Bertie ; El Omari, Kamel ; Bishop, Benjamin ; Pardon, Els ; Schwab, Rebekka A. ; Malinauskas, Tomas ; Qian, Mingxing ; Duman, Ramona ; Covey, Douglas F. ; Steyaert, Jan ; Wagner, Armin ; Sansom, Mark S. P. ; Rohatgi, Rajat ; Siebold, Christian
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2019-10, Vol.15 (10), p.975-982
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GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway
Author / Creator:Hoppe, Nicholas ; Harrison, Simone ; Hwang, Sun-Hee ; Chen, Ziwei ; Karelina, Masha ; Deshpande, Ishan ; Suomivuori, Carl-Mikael ; Palicharla, Vivek R. ; Berry, Samuel P. ; Tschaikner, Philipp ; Regele, Dominik ; Covey, Douglas F. ; Stefan, Eduard ; Marks, Debora S. ; Reiter, Jeremy F. ; Dror, Ron O. ; Evers, Alex S. ; Mukhopadhyay, Saikat ; Manglik, Aashish
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2024-04, Vol.31 (4), p.667-677
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Energetics by NMR: Site-Specific Binding in a Positively Cooperative System
Author / Creator:Tochtrop, Gregory P. ; Richter, Klaus ; Tang, Changguo ; Toner, James J. ; Covey, Douglas F. ; Cistola, David P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-02, Vol.99 (4), p.1847-1852
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Select record 40
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Phosphorylation of CRYAB induces a condensatopathy to worsen post–myocardial infarction left ventricular remodeling
Author / Creator:Islam, Moydul ; Rawnsley, David R. ; Ma, Xiucui ; Navid, Walter ; Zhao, Chen ; Guan, Xumin ; Foroughi, Layla ; Murphy, John T. ; Navid, Honora ; Weinheimer, Carla J. ; Kovacs, Attila ; Nigro, Jessica ; Diwan, Aaradhya ; Chang, Ryan P. ; Kumari, Minu ; Young, Martin E. ; Razani, Babak ; Margulies, Kenneth B. ; Abdellatif, Mahmoud ; Sedej, Simon ; Javaheri, Ali ; Covey, Douglas F. ; Mani, Kartik ; Diwan, Abhinav
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2025-04, Vol.135 (7)
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Showing 21 to 40 of 72 results

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Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells

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Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model

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Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling

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Enantioselective Protein-Sterol Interactions Mediate Regulation of Both Prokaryotic and Eukaryotic Inward Rectifier K+ Channels by Cholesterol

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Anticonvulsant Medications Extend Worm Life-Span

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The Mechanism of Enantioselective Neurosteroid Actions on GABAA Receptors

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Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice

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Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone

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Pregnane X Receptor (PXR) Activation: A Mechanism for Neuroprotection in a Mouse Model of Niemann-Pick C Disease

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Cholesterol Tuning of BK Ethanol Response Is Enantioselective, and Is a Function of Accompanying Lipids

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A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

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Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels

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5β-Dihydrosteroids: Formation and Properties

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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

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Effects of Natural and Enantiomeric Cholesterol on the Thermotropic Phase Behavior and Structure of Egg Sphingomyelin Bilayer Membranes

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The Synthetic Enantiomer of Pregnenolone Sulfate is very Active on Memory in Rats and Mice, Even More so Than Its Physiological Neurosteroid Counterpart: Distinct Mechanisms?

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The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

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GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway

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Energetics by NMR: Site-Specific Binding in a Positively Cooperative System

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Phosphorylation of CRYAB induces a condensatopathy to worsen post–myocardial infarction left ventricular remodeling

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