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Select record 21
ArticlesPeer ReviewedFull Text
Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross
Author / Creator:Gupta, Ankit ; Bokhari, Abdullah A. B. ; Pillai, Ajay D. ; Crater, Anna K. ; Gezelle, Jeanine ; Saggu, Gagandeep ; Nasamu, Armiyaw S. ; Ganesan, Suresh M. ; Niles, Jacquin C. ; Desai, Sanjay A.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-02, Vol.16 (2), p.e1008363-e1008363
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EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX
Author / Creator:Garten, Matthias ; Nasamu, Armiyaw S. ; Niles, Jacquin C. ; Zimmerberg, Joshua ; Goldberg, Daniel E. ; Beck, Josh R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2018-10, Vol.3 (10), p.1090-1098
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Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites
Author / Creator:Russell, Timothy James ; De Silva, Erandi K. ; Crowley, Valerie M. ; Shaw-Saliba, Kathryn ; Dube, Namita ; Josling, Gabrielle ; Pasaje, Charisse Flerida A. ; Kouskoumvekaki, Irene ; Panagiotou, Gianni ; Niles, Jacquin C. ; Jacobs-Lorena, Marcelo ; Denise Okafor, C. ; Gamo, Francisco-Javier ; Llinás, Manuel
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-10, Vol.18 (10), p.e1010887
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Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death
Author / Creator:Lu, Kuan-Yi ; Pasaje, Charisse Flerida A ; Srivastava, Tamanna ; Loiselle, David R ; Niles, Jacquin C ; Derbyshire, Emily
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-09, Vol.9
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Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
Author / Creator:Dankwa, Selasi ; Lim, Caeul ; Bei, Amy K. ; Jiang, Rays H. Y. ; Abshire, James R. ; Patel, Saurabh D. ; Goldberg, Jonathan M. ; Moreno, Yovany ; Kono, Maya ; Niles, Jacquin C. ; Duraisingh, Manoj T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-04, Vol.7 (1), p.11187-11187, Article 11187
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Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers
Author / Creator:Niles, Jacquin C ; DeRisi, Joseph L ; Marletta, Michael A
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (32), p.13266-13271
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Inducible Control of Subcellular RNA Localization Using a Synthetic Protein-RNA Aptamer Interaction
Author / Creator:Belmont, Brian J. ; Niles, Jacquin C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-10, Vol.7 (10), p.e46868
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Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum
Author / Creator:Wagner, Jeffrey C ; Platt, Randall J ; Goldfless, Stephen J ; Zhang, Feng ; Niles, Jacquin C
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2014-09, Vol.11 (9), p.915-918
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Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
Author / Creator:Nasamu, Armiyaw S. ; Glushakova, Svetlana ; Russo, Ilaria ; Vaupel, Barbara ; Oksman, Anna ; Kim, Arthur S. ; Fremont, Daved H. ; Tolia, Niraj ; Beck, Josh R. ; Meyers, Marvin J. ; Niles, Jacquin C. ; Zimmerberg, Joshua ; Goldberg, Daniel E.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-10, Vol.358 (6362), p.518-522
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Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX)
Author / Creator:Birch, Christina M. ; Hou, Han Wei ; Han, Jongyoon ; Niles, Jacquin C.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-07, Vol.5 (1), p.11347-11347, Article 11347
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Versatile control of Plasmodium falciparum gene expression with an inducible protein–RNA interaction
Author / Creator:Goldfless, Stephen J. ; Wagner, Jeffrey C. ; Niles, Jacquin C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-11, Vol.5 (1), p.5329-5329, Article 5329
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Select record 32
ArticlesPeer ReviewedFull Text
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
Author / Creator:Bopp, Selina ; Pasaje, Charisse Flerida A. ; Summers, Robert L. ; Magistrado-Coxen, Pamela ; Schindler, Kyra A. ; Corpas-Lopez, Victoriano ; Yeo, Tomas ; Mok, Sachel ; Dey, Sumanta ; Smick, Sebastian ; Nasamu, Armiyaw S. ; Demas, Allison R. ; Milne, Rachel ; Wiedemar, Natalie ; Corey, Victoria ; Gomez-Lorenzo, Maria De Gracia ; Franco, Virginia ; Early, Angela M. ; Lukens, Amanda K. ; Milner, Danny ; Furtado, Jeremy ; Gamo, Francisco-Javier ; Winzeler, Elizabeth A. ; Volkman, Sarah K. ; Duffey, Maëlle ; Laleu, Benoît ; Fidock, David A. ; Wyllie, Susan ; Niles, Jacquin C. ; Wirth, Dyann F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-03, Vol.14 (1), p.1455-15, Article 1455
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Select record 33
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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
Author / Creator:de Vries, Laura E. ; Jansen, Patrick A. M. ; Barcelo, Catalina ; Munro, Justin ; Verhoef, Julie M. J. ; Pasaje, Charisse Flerida A. ; Rubiano, Kelly ; Striepen, Josefine ; Abla, Nada ; Berning, Luuk ; Bolscher, Judith M. ; Demarta-Gatsi, Claudia ; Henderson, Rob W. M. ; Huijs, Tonnie ; Koolen, Karin M. J. ; Tumwebaze, Patrick K. ; Yeo, Tomas ; Aguiar, Anna C. C. ; Angulo-Barturen, Iñigo ; Churchyard, Alisje ; Baum, Jake ; Fernández, Benigno Crespo ; Fuchs, Aline ; Gamo, Francisco-Javier ; Guido, Rafael V. C. ; Jiménez-Diaz, María Belén ; Pereira, Dhelio B. ; Rochford, Rosemary ; Roesch, Camille ; Sanz, Laura M. ; Trevitt, Graham ; Witkowski, Benoit ; Wittlin, Sergio ; Cooper, Roland A. ; Rosenthal, Philip J. ; Sauerwein, Robert W. ; Schalkwijk, Joost ; Hermkens, Pedro H. H. ; Bonnert, Roger V. ; Campo, Brice ; Fidock, David A. ; Llinás, Manuel ; Niles, Jacquin C. ; Kooij, Taco W. A. ; Dechering, Koen J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.2158-2158, Article 2158
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Select record 34
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An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum
Author / Creator:Wagner, Jeffrey C ; Goldfless, Stephen J ; Ganesan, Suresh M ; Lee, Marcus CS ; Fidock, David A ; Niles, Jacquin C
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2013-10, Vol.12 (1), p.373-373, Article 373
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Select record 35
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Computational synchronization of microarray data with application to Plasmodium falciparum
Author / Creator:Zhao, Wei ; Dauwels, Justin ; Niles, Jacquin C ; Cao, Jianshu
Publisher:England: BioMed Central
Journal title:Proteome science, 2012-06, Vol.10 (S1), p.S10-S10, Article S10
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Peroxynitrite Reaction Products of 3′,5′-di-O-acetyl-8-oxo-7,8-dihydro-2′-deoxyguanosine
Author / Creator:Niles, Jacquin C. ; Burney, Samar ; Singh, Sukhjeet P. ; Wishnok, John S. ; Tannenbaum, Steven R.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (21), p.11729-11734
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Select record 37
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A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma
Author / Creator:Sidik, Saima ; Valleau, Dylan ; Acevedo-Sánchez, Yamilex ; Godoy, Luiz C ; Charisse Flerida A Pasaje ; Huynh, My-Hang ; Carruthers, Vern B ; Niles, Jacquin C ; Lourido, Sebastian
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-11
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Select record 38
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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
Author / Creator:Xie, Stanley C. ; Wang, Yinuo ; Morton, Craig J. ; Metcalfe, Riley D. ; Dogovski, Con ; Pasaje, Charisse Flerida A. ; Dunn, Elyse ; Luth, Madeline R. ; Kumpornsin, Krittikorn ; Istvan, Eva S. ; Park, Joon Sung ; Fairhurst, Kate J. ; Ketprasit, Nutpakal ; Yeo, Tomas ; Yildirim, Okan ; Bhebhe, Mathamsanqa N. ; Klug, Dana M. ; Rutledge, Peter J. ; Godoy, Luiz C. ; Dey, Sumanta ; De Souza, Mariana Laureano ; Siqueira-Neto, Jair L. ; Du, Yawei ; Puhalovich, Tanya ; Amini, Mona ; Shami, Gerry ; Loesbanluechai, Duangkamon ; Nie, Shuai ; Williamson, Nicholas ; Jana, Gouranga P. ; Maity, Bikash C. ; Thomson, Patrick ; Foley, Thomas ; Tan, Derek S. ; Niles, Jacquin C. ; Han, Byung Woo ; Goldberg, Daniel E. ; Burrows, Jeremy ; Fidock, David A. ; Lee, Marcus C. S. ; Winzeler, Elizabeth A. ; Griffin, Michael D. W. ; Todd, Matthew H. ; Tilley, Leann
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.937-18, Article 937
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Select record 39
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Identification of Antimalarial Compounds that Inhibit Apicomplexan AP2 Proteins in the Human Malaria Parasite Plasmodium falciparum
Author / Creator:Russell, Timothy J ; De Silva, Erandi K ; Crowley, Valerie ; Shaw-Saliba, Kathryn ; Dube, Namita ; Josling, Gabrielle ; Charisse Flerida A Pasaje ; Kouskoumvekaki, Irene ; Panagiotou, Gianni ; Niles, Jacquin C ; Jacobs-Lorena, Marcelo ; Oka, C Denise ; Francisco-Javier Gamo ; Llinas, Manuel
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-04
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Atg8 is essential specifically for an autophagy-independent function in apicoplast biogenesis in blood-stage malaria parasites
Author / Creator:Walczak, Marta ; Ganesan, Suresh M ; Niles, Jacquin C ; Yeh, Ellen
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2017-10
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Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross

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EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX

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Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites

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Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

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Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

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Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers

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Inducible Control of Subcellular RNA Localization Using a Synthetic Protein-RNA Aptamer Interaction

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Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

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Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

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Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX)

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Versatile control of Plasmodium falciparum gene expression with an inducible protein–RNA interaction

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Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

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An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum

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Computational synchronization of microarray data with application to Plasmodium falciparum

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Peroxynitrite Reaction Products of 3′,5′-di-O-acetyl-8-oxo-7,8-dihydro-2′-deoxyguanosine

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A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma

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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

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Identification of Antimalarial Compounds that Inhibit Apicomplexan AP2 Proteins in the Human Malaria Parasite Plasmodium falciparum

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Atg8 is essential specifically for an autophagy-independent function in apicoplast biogenesis in blood-stage malaria parasites

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