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ArticlesPeer ReviewedFull Text
The role of TSC1 and TSC2 proteins in neuronal axons
Author / Creator:Karalis, Vasiliki ; Wood, Delaney ; Teaney, Nicole A. ; Sahin, Mustafa
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2024-04, Vol.29 (4), p.1165-1178
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mTORC1 Activation in Chx10-Specific Tsc1 Knockout Mice Accelerates Retina Aging and Degeneration
Author / Creator:Rao, Yu-Qing ; Zhou, Yu-Tong ; Zhou, Wenchuan ; Li, Jia-Kai ; Li, Baojie ; Li, Jing
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.6715758-6715758
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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma
Author / Creator:Wang, Yuqiong ; Zhang, Xiyu ; Tang, Wei ; Lin, Zhenghong ; Xu, Limei ; Dong, Ruifen ; Li, Yinuo ; Li, Jieyin ; Zhang, Zaixin ; Li, Xiangzhi ; Zhao, Ling ; Wei, Jian-Jun ; Shao, Changshun ; Kong, Beihua ; Liu, Zhaojian
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-12, Vol.24 (12), p.2089-2100
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TSC1 regulates the balance between effector and regulatory T cells
Author / Creator:Park, Yoon ; Jin, Hyung-Seung ; Lopez, Justine ; Elly, Chris ; Kim, Gisen ; Murai, Masako ; Kronenberg, Mitchell ; Liu, Yun-Cai
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-12, Vol.123 (12), p.5165-5178
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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-[kappa]B in high-grade serous ovarian carcinoma
Author / Creator:Wang, Yuqiong ; Zhang, Xiyu ; Tang, Wei ; Lin, Zhenghong ; Xu, Limei ; Dong, Ruifen ; Li, Yinuo ; Li, Jieyin ; Zhang, Zaixin ; Li, Xiangzhi ; Zhao, Ling ; Wei, Jian-jun ; Shao, Changshun ; Kong, Beihua ; Liu, Zhaojian
Publisher:Rome: Nature Publishing Group
Journal title:Cell death and differentiation, 2017-12, Vol.24 (12), p.2089
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MiR‐451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1
Author / Creator:Song, Lei ; Su, Ming ; Wang, Shuiyun ; Zou, Yubao ; Wang, Xiaojian ; Wang, Yilu ; Cui, Hongli ; Zhao, Peng ; Hui, Rutai ; Wang, Jizheng
Publisher:England: BlackWell Publishing Ltd
Journal title:Journal of cellular and molecular medicine, 2014-11, Vol.18 (11), p.2266-2274
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miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1
Author / Creator:Chen, Yanting ; Li, Shanxiang ; He, Hong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.19353-12, Article 19353
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TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication
Author / Creator:Ho, Daniel W H ; Chan, Lo K ; Chiu, Yung T ; Xu, Iris M J ; Poon, Ronnie T P ; Cheung, Tan T ; Tang, Chung N ; Tang, Victor W L ; Lo, Irene L O ; Lam, Polly W Y ; Yau, Derek T W ; Li, Miao X ; Wong, Chun M ; Ng, Irene O L
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-08, Vol.66 (8), p.1496-1506
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Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing
Author / Creator:Tyburczy, Magdalena E. ; Dies, Kira A. ; Glass, Jennifer ; Camposano, Susana ; Chekaluk, Yvonne ; Thorner, Aaron R. ; Lin, Ling ; Krueger, Darcy ; Franz, David N. ; Thiele, Elizabeth A. ; Sahin, Mustafa ; Kwiatkowski, David J.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-11, Vol.11 (11), p.e1005637-e1005637
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Tackling Tsc1 to Promote Nephrogenesis
Author / Creator:Ingelfinger, Julie R
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-12, Vol.379 (25), p.2476-2478
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Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss
Author / Creator:Amegandjin, Clara A. ; Choudhury, Mayukh ; Jadhav, Vidya ; Carriço, Josianne Nunes ; Quintal, Ariane ; Berryer, Martin ; Snapyan, Marina ; Chattopadhyaya, Bidisha ; Saghatelyan, Armen ; Di Cristo, Graziella
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3653-3653, Article 3653
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MicroRNA‐92b‐3p is a prognostic oncomiR that targets TSC1 in clear cell renal cell carcinoma
Author / Creator:Wang, Cong ; Uemura, Motohide ; Tomiyama, Eisuke ; Matsushita, Makoto ; Koh, Yoko ; Nakano, Kosuke ; Hayashi, Yujiro ; Ishizuya, Yu ; Jingushi, Kentaro ; Kato, Taigo ; Hatano, Koji ; Kawashima, Atsunari ; Ujike, Takeshi ; Nagahara, Akira ; Fujita, Kazutoshi ; Imamura, Ryoichi ; Tsujikawa, Kazutake ; Nonomura, Norio
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-04, Vol.111 (4), p.1146-1155
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TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis
Author / Creator:Shi, Lei ; Chen, Xia ; Zang, Aiping ; Li, Tiantian ; Hu, Yanxiang ; Ma, Shixin ; Lü, Mengdie ; Yin, Huiyong ; Wang, Haikun ; Zhang, Xiaoming ; Zhang, Bei ; Leng, Qibin ; Yang, Jinbo ; Xiao, Hui
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2019-08, Vol.17 (8), p.e3000420-e3000420
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The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function
Author / Creator:Yang, Kai ; Neale, Geoffrey ; Green, Douglas R ; He, Weifeng ; Chi, Hongbo
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2011-09, Vol.12 (9), p.888-897
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Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: genotype – phenotype correlations and comparison of diagnostic DNA techniques in Tuberous Sclerosis Complex
Author / Creator:Sancak, Ozgur ; Nellist, Mark ; Goedbloed, Miriam ; Elfferich, Peter ; Wouters, Cokkie ; Maat-Kievit, Anneke ; Zonnenberg, Bernard ; Verhoef, Senno ; Halley, Dicky ; van den Ouweland, Ans
Publisher:Cham: Springer International Publishing
Journal title:European journal of human genetics : EJHG, 2005-06, Vol.13 (6), p.731-741
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Splicing Analysis of Exonic TSC1 and TSC2 Gene Variants Causing Tuberous Sclerosis Complex
Author / Creator:You, Qingqing ; Liu, Jingwei ; Zhang, Ran ; Wang, Zhi ; Zhang, Bingying ; Guo, Wencong ; Xu, Ning ; Bottillo, Irene ; Shao, Leping
Publisher:Hoboken: John Wiley & Sons, Inc
Journal title:Human mutation, 2025-01, Vol.2025
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Absence of TSC1 Accelerates CD8 + T cell-mediated Acute Cardiac Allograft Rejection
Author / Creator:Tan, Liang ; Xu, Yanan ; Lan, Gongbin ; Wang, Hongxia ; Liang, Zhanfeng ; Zhang, Zhaoqi ; Tian, Qianchuan ; Hou, Yangxiao ; Zhao, Yong ; Xie, Xubiao
Publisher:JKL International LLC
Journal title:Aging and disease, 2022-10, Vol.13 (5), p.1562-1575
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Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
Author / Creator:Mrozek, Evelyn M. ; Bajaj, Vineeta ; Guo, Yanan ; Malinowska, Izabela A. ; Zhang, Jianming ; Kwiatkowski, David J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-04, Vol.16 (4), p.e0248380-e0248380
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Mutation spectrums of TSC1 and TSC2 in Chinese women with lymphangioleiomyomatosis (LAM)
Author / Creator:Liu, Jie ; Zhao, Weiwei ; Ou, Xiaohua ; Zhao, Zhen ; Hu, Changming ; Sun, Mingming ; Liu, Feifei ; Deng, Junhao ; Gu, Weili ; An, Jiaying ; Zhang, Qingling ; Zhang, Xiaoxian ; Xie, Jiaxing ; Li, Shiyue ; Chen, Rongchang ; Yu, Shihui ; Zhong, Nanshan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-12, Vol.14 (12), p.e0226400-e0226400
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Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development
Author / Creator:Giannikou, Krinio ; Malinowska, Izabela A ; Pugh, Trevor J ; Yan, Rachel ; Tseng, Yuen-Yi ; Oh, Coyin ; Kim, Jaegil ; Tyburczy, Magdalena E ; Chekaluk, Yvonne ; Liu, Yang ; Alesi, Nicola ; Finlay, Geraldine A ; Wu, Chin-Lee ; Signoretti, Sabina ; Meyerson, Matthew ; Getz, Gad ; Boehm, Jesse S ; Henske, Elizabeth P ; Kwiatkowski, David J
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2016-08, Vol.12 (8), p.e1006242
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Showing 21 to 40 of 1,512 results

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The role of TSC1 and TSC2 proteins in neuronal axons

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mTORC1 Activation in Chx10-Specific Tsc1 Knockout Mice Accelerates Retina Aging and Degeneration

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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma

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TSC1 regulates the balance between effector and regulatory T cells

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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-[kappa]B in high-grade serous ovarian carcinoma

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MiR‐451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1

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miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1

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TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication

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Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing

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Tackling Tsc1 to Promote Nephrogenesis

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Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss

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MicroRNA‐92b‐3p is a prognostic oncomiR that targets TSC1 in clear cell renal cell carcinoma

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TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis

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The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function

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Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: genotype – phenotype correlations and comparison of diagnostic DNA techniques in Tuberous Sclerosis Complex

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Splicing Analysis of Exonic TSC1 and TSC2 Gene Variants Causing Tuberous Sclerosis Complex

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Absence of TSC1 Accelerates CD8 + T cell-mediated Acute Cardiac Allograft Rejection

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Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer

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Mutation spectrums of TSC1 and TSC2 in Chinese women with lymphangioleiomyomatosis (LAM)

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Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development

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