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135 results for ADAM10+Protein+-+metabolism

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ArticlesPeer ReviewedFull Text
Decoy exosomes provide protection against bacterial toxins
Author / Creator:Keller, Matthew D. ; Ching, Krystal L. ; Liang, Feng-Xia ; Dhabaria, Avantika ; Tam, Kayan ; Ueberheide, Beatrix M. ; Unutmaz, Derya ; Torres, Victor J. ; Cadwell, Ken
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7798), p.260-264
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Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma
Author / Creator:Venkatesh, Humsa S. ; Tam, Lydia T. ; Woo, Pamelyn J. ; Lennon, James ; Nagaraja, Surya ; Gillespie, Shawn M. ; Ni, Jing ; Duveau, Damien Y. ; Morris, Patrick J. ; Zhao, Jean J. ; Thomas, Craig J. ; Monje, Michelle
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-09, Vol.549 (7673), p.533-537
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TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
Author / Creator:Hurst, Liam A. ; Dunmore, Benjamin J. ; Long, Lu ; Crosby, Alexi ; Al-Lamki, Rafia ; Deighton, John ; Southwood, Mark ; Yang, Xudong ; Nikolic, Marko Z. ; Herrera, Blanca ; Inman, Gareth J. ; Bradley, John R. ; Rana, Amer A. ; Upton, Paul D. ; Morrell, Nicholas W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-01, Vol.8 (1), p.14079-14079, Article 14079
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Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation
Author / Creator:Riethmueller, Steffen ; Somasundaram, Prasath ; Ehlers, Johanna C. ; Hung, Chien-Wen ; Flynn, Charlotte M. ; Lokau, Juliane ; Agthe, Maria ; Düsterhöft, Stefan ; Zhu, Yijue ; Grötzinger, Joachim ; Lorenzen, Inken ; Koudelka, Tomas ; Yamamoto, Kosuke ; Pickhinke, Ute ; Wichert, Rielana ; Becker-Pauly, Christoph ; Rädisch, Marisa ; Albrecht, Alexander ; Hessefort, Markus ; Stahnke, Dominik ; Unverzagt, Carlo ; Rose-John, Stefan ; Tholey, Andreas ; Garbers, Christoph
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2017-01, Vol.15 (1), p.e2000080-e2000080
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An Alzheimer‐associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function
Author / Creator:Schlepckow, Kai ; Kleinberger, Gernot ; Fukumori, Akio ; Feederle, Regina ; Lichtenthaler, Stefan F ; Steiner, Harald ; Haass, Christian
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2017-10, Vol.9 (10), p.1356-1365
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TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant
Author / Creator:Thornton, Peter ; Sevalle, Jean ; Deery, Michael J ; Fraser, Graham ; Zhou, Ye ; Ståhl, Sara ; Franssen, Elske H ; Dodd, Roger B ; Qamar, Seema ; Gomez Perez‐Nievas, Beatriz ; Nicol, Louise SC ; Eketjäll, Susanna ; Revell, Jefferson ; Jones, Clare ; Billinton, Andrew ; St George‐Hyslop, Peter H ; Chessell, Iain ; Crowther, Damian C
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2017-10, Vol.9 (10), p.1366-1378
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Degradome of soluble ADAM10 and ADAM17 metalloproteases
Author / Creator:Scharfenberg, Franka ; Helbig, Andreas ; Sammel, Martin ; Benzel, Julia ; Schlomann, Uwe ; Peters, Florian ; Wichert, Rielana ; Bettendorff, Maximilian ; Schmidt-Arras, Dirk ; Rose-John, Stefan ; Moali, Catherine ; Lichtenthaler, Stefan F. ; Pietrzik, Claus U. ; Bartsch, Jörg W. ; Tholey, Andreas ; Becker-Pauly, Christoph
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2020-01, Vol.77 (2), p.331-350
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Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells
Author / Creator:Romero, Yeni ; Wise, Randi ; Zolkiewska, Anna
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2020-01, Vol.69 (1), p.43-55
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Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells
Author / Creator:Caolo, Vincenza ; Debant, Marjolaine ; Endesh, Naima ; Futers, T Simon ; Lichtenstein, Laeticia ; Bartoli, Fiona ; Parsonage, Gregory ; Jones, Elizabeth AV ; Beech, David J
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2020-06, Vol.9
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Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10
Author / Creator:Hammad, Hamida ; Vanderkerken, Matthias ; Pouliot, Philippe ; Deswarte, Kim ; Toussaint, Wendy ; Vergote, Karl ; Vandersarren, Lana ; Janssens, Sophie ; Ramou, Ioanna ; Savvides, Savvas N ; Haigh, Jody J ; Hendriks, Rudi ; Kopf, Manfred ; Craessaerts, Katleen ; de Strooper, Bart ; Kearney, John F ; Conrad, Daniel H ; Lambrecht, Bart N
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2017-03, Vol.18 (3), p.313-320
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The metalloproteinase ADAM10 requires its activity to sustain surface expression
Author / Creator:Seifert, Anke ; Düsterhöft, Stefan ; Wozniak, Justyna ; Koo, Chek Z. ; Tomlinson, Michael G. ; Nuti, Elisa ; Rossello, Armando ; Cuffaro, Doretta ; Yildiz, Daniela ; Ludwig, Andreas
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2021-01, Vol.78 (2), p.715-732
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Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
Author / Creator:Kuhn, Peer-Hendrik ; Colombo, Alessio Vittorio ; Schusser, Benjamin ; Dreymueller, Daniela ; Wetzel, Sebastian ; Schepers, Ute ; Herber, Julia ; Ludwig, Andreas ; Kremmer, Elisabeth ; Montag, Dirk ; Müller, Ulrike ; Schweizer, Michaela ; Saftig, Paul ; Bräse, Stefan ; Lichtenthaler, Stefan F
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-01, Vol.5
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Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis
Author / Creator:Alfano, Danielle N. ; Miller, Mark J. ; Bubeck Wardenburg, Juliane
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-12, Vol.133 (23), p.1-12
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A novel pan‐cancer biomarker plasma heat shock protein 90alpha and its diagnosis determinants in clinic
Author / Creator:Liu, Wei ; Li, Jie ; Zhang, Ping ; Hou, Qiaoyun ; Feng, Shi ; Liu, Lisheng ; Cui, Dawei ; Shi, Hubing ; Fu, Yan ; Luo, Yongzhang
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2019-09, Vol.110 (9), p.2941-2959
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Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein
Author / Creator:Mohammadi, Behnam ; Song, Feizhi ; Matamoros-Angles, Andreu ; Shafiq, Mohsin ; Damme, Markus ; Puig, Berta ; Glatzel, Markus ; Altmeppen, Hermann Clemens
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cell and tissue research, 2023-04, Vol.392 (1), p.215-234
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Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions
Author / Creator:Aguilar-Calvo, Patricia ; Sevillano, Alejandro M. ; Bapat, Jaidev ; Soldau, Katrin ; Sandoval, Daniel R. ; Altmeppen, Hermann C. ; Linsenmeier, Luise ; Pizzo, Donald P. ; Geschwind, Michael D. ; Sanchez, Henry ; Appleby, Brian S. ; Cohen, Mark L. ; Safar, Jiri G. ; Edland, Steven D. ; Glatzel, Markus ; Nilsson, K. Peter R. ; Esko, Jeffrey D. ; Sigurdson, Christina J.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2020-03, Vol.139 (3), p.527-546
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ADAM10-a “multitasker” in sepsis: focus on its posttranslational target
Author / Creator:Liao, Shuanglin ; Lin, Yao ; Liu, Lizhen ; Yang, Shuai ; Lin, YingYing ; He, Junbing ; Shao, Yiming
Publisher:Cham: Springer International Publishing
Journal title:Inflammation research, 2023-03, Vol.72 (3), p.395-423
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Cognitive function and retinal biomarkers as novel approach to diagnosing and assessing autism spectrum disorder
Author / Creator:Al-Mazidi, Sarah ; Alhowikan, Abdulrahman ; Elamin, Nadra ; Abualnaja, Amani ; Al-Mnaizel, Ahmad ; Alharbi, Turki ; Al-Ayadhi, Laila
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-05, Vol.15 (1), p.17946-9, Article 17946
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Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis
Author / Creator:Xiao, Wenyuan ; Pinilla-Baquero, Alejandro ; Faulkner, John ; Song, Xuehong ; Prabhakar, Pradeep ; Qiu, Hong ; Moremen, Kelley W. ; Ludwig, Andreas ; Dempsey, Peter J. ; Azadi, Parastoo ; Wang, Lianchun
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-03, Vol.12 (1), p.4352-4352, Article 4352
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Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling
Author / Creator:Flynn, Charlotte M. ; Garbers, Yvonne ; Lokau, Juliane ; Wesch, Daniela ; Schulte, Dominik M. ; Laudes, Matthias ; Lieb, Wolfgang ; Aparicio-Siegmund, Samadhi ; Garbers, Christoph
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-05, Vol.9 (1), p.7306-7306, Article 7306
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Showing 1 to 20 of 135 results

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Decoy exosomes provide protection against bacterial toxins

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Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

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TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

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Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation

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An Alzheimer‐associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function

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TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

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Degradome of soluble ADAM10 and ADAM17 metalloproteases

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Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells

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Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

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Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10

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The metalloproteinase ADAM10 requires its activity to sustain surface expression

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Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

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Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis

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A novel pan‐cancer biomarker plasma heat shock protein 90alpha and its diagnosis determinants in clinic

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Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein

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Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions

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ADAM10-a “multitasker” in sepsis: focus on its posttranslational target

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Cognitive function and retinal biomarkers as novel approach to diagnosing and assessing autism spectrum disorder

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Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis

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Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling

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