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Cryo-EM structures of the TMEM16A calcium-activated chloride channel
Author / Creator:Dang, Shangyu ; Feng, Shengjie ; Tien, Jason ; Peters, Christian J. ; Bulkley, David ; Lolicato, Marco ; Zhao, Jianhua ; Zuberbühler, Kathrin ; Ye, Wenlei ; Qi, Lijun ; Chen, Tingxu ; Craik, Charles S. ; Jan, Yuh Nung ; Minor, Daniel L. ; Cheng, Yifan ; Jan, Lily Yeh
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7685), p.426-429
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Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
Author / Creator:Paulino, Cristina ; Kalienkova, Valeria ; Lam, Andy K. M. ; Neldner, Yvonne ; Dutzler, Raimund
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7685), p.421-425
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Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
Author / Creator:Paulino, Cristina ; Neldner, Yvonne ; Lam, Andy KM ; Kalienkova, Valeria ; Brunner, Janine Denise ; Schenck, Stephan ; Dutzler, Raimund
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2017-05, Vol.6
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Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy
Author / Creator:Vyas, Avani ; Gomez-Casal, Roberto ; Cruz-Rangel, Silvia ; Villanueva, Hugo ; Sikora, Andrew G. ; Rajagopalan, Pavithra ; Basu, Devraj ; Pacheco, Jonathan ; Hammond, Gerald R. V. ; Kiselyov, Kirill ; Duvvuri, Umamaheswar
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (12), p.1-12
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Down-Regulation of microRNA-132 is Associated with Poor Prognosis of Colorectal Cancer
Author / Creator:Mokutani, Yukako ; Uemura, Mamoru ; Munakata, Koji ; Okuzaki, Daisuke ; Haraguchi, Naotsugu ; Takahashi, Hidekazu ; Nishimura, Junichi ; Hata, Taishi ; Murata, Kohei ; Takemasa, Ichiro ; Mizushima, Tsunekazu ; Doki, Yuichiro ; Mori, Masaki ; Yamamoto, Hirofumi
Publisher:Cham: Springer International Publishing
Journal title:Annals of surgical oncology, 2016-12, Vol.23 (Suppl 5), p.599-608
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Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling transduction
Author / Creator:Sun, Weijia ; Guo, Shuai ; Li, Yuheng ; Li, JianWei ; Liu, Caizhi ; Chen, Yafei ; Wang, Xuzhao ; Tan, Yingjun ; Tian, Hua ; Wang, Cheng ; Du, Ruikai ; Zhong, Guohui ; Shi, Sai ; Ma, Biao ; Qu, Chang ; Fu, Jingxuan ; Jin, Xiaoyan ; Zhao, Dingsheng ; Zhan, Yong ; Ling, Shukuan ; An, Hailong ; Li, Yingxian
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2899-2899, Article 2899
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Epithelial Chloride Transport by CFTR Requires TMEM16A
Author / Creator:Benedetto, Roberta ; Ousingsawat, Jiraporn ; Wanitchakool, Podchanart ; Zhang, Yong ; Holtzman, Michael J. ; Amaral, Margarida ; Rock, Jason R. ; Schreiber, Rainer ; Kunzelmann, Karl
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-09, Vol.7 (1), p.12397-13, Article 12397
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TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis
Author / Creator:Crottès, David ; Lin, Yu-Hsiu T. ; Peters, Christian J. ; Gilchrist, John M. ; Wiita, Arun P. ; Jan, Yuh Nung ; Jan, Lily Yeh
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (26), p.13026-13035
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Gating the pore of the calcium-activated chloride channel TMEM16A
Author / Creator:Lam, Andy K. M. ; Rheinberger, Jan ; Paulino, Cristina ; Dutzler, Raimund
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.785-13, Article 785
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An inner activation gate controls TMEM16F phospholipid scrambling
Author / Creator:Le, Trieu ; Jia, Zhiguang ; Le, Son C. ; Zhang, Yang ; Chen, Jianhan ; Yang, Huanghe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1846-13, Article 1846
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An outer-pore gate modulates the pharmacology of the TMEM16A channel
Author / Creator:Dinsdale, Ria L. ; Pipatpolkai, Tanadet ; Agostinelli, Emilio ; Russell, Angela J. ; Stansfeld, Phillip J. ; Tammaro, Paolo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (34), p.1-10
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Inhibition of ANO1 by Cis- and Trans-Resveratrol and Their Anticancer Activity in Human Prostate Cancer PC-3 Cells
Author / Creator:Jeon, Dongkyu ; Jo, Minjae ; Lee, Yechan ; Park, So-Hyeon ; Phan, Hong Thi Lam ; Nam, Joo Hyun ; Namkung, Wan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-01, Vol.24 (2), p.1186
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Identification of novel TMEM16A blockers through integrated virtual screening, molecular dynamics, and experimental studies
Author / Creator:Sangkhawasi, Mattanun ; Pitaktrakul, Wichuda ; Khumjiang, Rungtiwa ; Shigeta, Yasuteru ; Muanprasat, Chatchai ; Hengphasatporn, Kowit ; Rungrotmongkol, Thanyada
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-04, Vol.15 (1), p.15065-11, Article 15065
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Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract
Author / Creator:Ousingsawat, Jiraporn ; Centeio, Raquel ; Schreiber, Rainer ; Kunzelmann, Karl
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Pflügers Archiv, 2024-02, Vol.476 (2), p.211-227
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Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans
Author / Creator:Zou, Wenjuan ; Fan, Yuedan ; Liu, Jia ; Cheng, Hankui ; Hong, Huitao ; Al-Sheikh, Umar ; Li, Shitian ; Zhu, Linhui ; Li, Rong ; He, Longyuan ; Tang, Yi-Quan ; Zhao, Guohua ; Zhang, Yongming ; Wang, Feng ; Zhan, Renya ; Zheng, Xiujue ; Kang, Lijun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1680-19
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Mechanism of pore opening in the calcium-activated chloride channel TMEM16A
Author / Creator:Lam, Andy K. M. ; Dutzler, Raimund
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.786-786, Article 786
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A Pharmacological Investigation of the TMEM16A Currents in Murine Skeletal Myogenic Precursor Cells
Author / Creator:Sciancalepore, Marina ; Ragnini, Asja ; Zacchi, Paola ; Borelli, Violetta ; D’Andrea, Paola ; Lorenzon, Paola ; Bernareggi, Annalisa
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-02, Vol.25 (4), p.2225
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Effect of Synthetic Vitreous Fiber Exposure on TMEM16A Channels in a Xenopus laevis Oocyte Model
Author / Creator:Zangari, Martina ; Zabucchi, Giuliano ; Conti, Martina ; Lorenzon, Paola ; Borelli, Violetta ; Constanti, Andrew ; Dellisanti, Francesco ; Leone, Sara ; Vaccari, Lisa ; Bernareggi, Annalisa
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (16), p.8661
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TMEM16A Maintains Acrosomal Integrity Through ERK1/2, RhoA, and Actin Cytoskeleton During Capacitation
Author / Creator:Roa-Espitia, Ana L. ; Reyes-Miguel, Tania ; Salgado-Lucio, Monica L. ; Cordero-Martínez, Joaquín ; Tafoya-Domínguez, Dennis ; Hernández-González, Enrique O.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-04, Vol.26 (8), p.3750
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TMEM16A: An Alternative Approach to Restoring Airway Anion Secretion in Cystic Fibrosis?
Author / Creator:Danahay, Henry ; Gosling, Martin
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-03, Vol.21 (7), p.2386
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Cryo-EM structures of the TMEM16A calcium-activated chloride channel

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Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM

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Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A

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Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy

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Down-Regulation of microRNA-132 is Associated with Poor Prognosis of Colorectal Cancer

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Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling transduction

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Epithelial Chloride Transport by CFTR Requires TMEM16A

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TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis

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Gating the pore of the calcium-activated chloride channel TMEM16A

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An inner activation gate controls TMEM16F phospholipid scrambling

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An outer-pore gate modulates the pharmacology of the TMEM16A channel

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Inhibition of ANO1 by Cis- and Trans-Resveratrol and Their Anticancer Activity in Human Prostate Cancer PC-3 Cells

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Identification of novel TMEM16A blockers through integrated virtual screening, molecular dynamics, and experimental studies

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Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract

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Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans

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Mechanism of pore opening in the calcium-activated chloride channel TMEM16A

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A Pharmacological Investigation of the TMEM16A Currents in Murine Skeletal Myogenic Precursor Cells

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Effect of Synthetic Vitreous Fiber Exposure on TMEM16A Channels in a Xenopus laevis Oocyte Model

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TMEM16A Maintains Acrosomal Integrity Through ERK1/2, RhoA, and Actin Cytoskeleton During Capacitation

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TMEM16A: An Alternative Approach to Restoring Airway Anion Secretion in Cystic Fibrosis?

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