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3,596 results for Apoptosis+Regulatory+Proteins+-+metabolism

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ArticlesPeer ReviewedFull Text
GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
Author / Creator:Nogueira, Tatiane C. ; Paula, Flavia M. ; Villate, Olatz ; Colli, Maikel L. ; Moura, Rodrigo F. ; Cunha, Daniel A. ; Marselli, Lorella ; Marchetti, Piero ; Cnop, Miriam ; Julier, Cécile ; Eizirik, Decio L.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-05, Vol.9 (5), p.e1003532
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Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism
Author / Creator:Raimondo, Stefania ; Saieva, Laura ; Corrado, Chiara ; Fontana, Simona ; Flugy, Anna ; Rizzo, Aroldo ; De Leo, Giacomo ; Alessandro, Riccardo
Publisher:England: BioMed Central Ltd
Journal title:Cell communication and signaling, 2015-02, Vol.13 (1), p.8-8, Article 8
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NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells
Author / Creator:Eisenbarth, Stephanie C. ; Williams, Adam ; Colegio, Oscar R. ; Meng, Hailong ; Strowig, Till ; Rongvaux, Anthony ; Henao-Mejia, Jorge ; Thaiss, Christoph A. ; Joly, Sophie ; Gonzalez, David G. ; Xu, Lan ; Zenewicz, Lauren A. ; Haberman, Ann M. ; Elinav, Eran ; Kleinstein, Steven H. ; Sutterwala, Fayyaz S. ; Flavell, Richard A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-04, Vol.484 (7395), p.510-513
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Pseudomonas aeruginosa Type-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome
Author / Creator:Faure, Emmanuel ; Mear, Jean-Baptiste ; Faure, Karine ; Normand, Sylvain ; Couturier-Maillard, Aurélie ; Grandjean, Teddy ; Balloy, Viviane ; Ryffel, Bernhard ; Dessein, Rodrigue ; Chignard, Michel ; Uyttenhove, Catherine ; Guery, Benoit ; Gosset, Philippe ; Chamaillard, Mathias ; Kipnis, Eric
Publisher:New York, NY: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2014-04, Vol.189 (7), p.799-811
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Puma is required for p53-induced depletion of adult stem cells
Author / Creator:Liu, Dongping ; Ou, Linda ; Clemenson, Gregory D. ; Chao, Connie ; Lutske, Marshall Eli ; Zambetti, Gerard P. ; Gage, Fred H. ; Xu, Yang
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2010-10, Vol.12 (10), p.993-998
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Pyruvate Kinase M2 Regulates Apoptosis of Intestinal Epithelial Cells in Crohn’s Disease
Author / Creator:Tang, Qiyun ; Ji, Qianqian ; Xia, Weiwei ; Li, Liren ; Bai, Jian’an ; Ni, Runzhou ; Qin, Yongwei
Publisher:Boston: Springer US
Journal title:Digestive diseases and sciences, 2015-02, Vol.60 (2), p.393-404
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Type I Interferon Drives Dendritic Cell Apoptosis via Multiple BH3-Only Proteins following Activation by PolyIC In Vivo
Author / Creator:Fuertes Marraco, Silvia A. ; Scott, Clare L. ; Bouillet, Philippe ; Ives, Annette ; Masina, Slavica ; Vremec, David ; Jansen, Elisa S. ; O'Reilly, Lorraine A. ; Schneider, Pascal ; Fasel, Nicolas ; Shortman, Ken ; Strasser, Andreas ; Acha-Orbea, Hans
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-06, Vol.6 (6), p.e20189
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Serine/Threonine Kinase 17A Is a Novel Candidate for Therapeutic Targeting in Glioblastoma
Author / Creator:Mao, Pingping ; Hever-Jardine, Mary P. ; Rahme, Gilbert J. ; Yang, Eric ; Tam, Janice ; Kodali, Anita ; Biswal, Bijesh ; Fadul, Camilo E. ; Gaur, Arti ; Israel, Mark A. ; Spinella, Michael J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-11, Vol.8 (11), p.e81803
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ArticlesPeer ReviewedFull Text
Acute Myeloid Leukemia-Targeted Toxin Activates Both Apoptotic and Necroptotic Death Mechanisms
Author / Creator:Horita, Henrick ; Frankel, Arthur E. ; Thorburn, Andrew
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-12, Vol.3 (12), p.e3909-e3909
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TSC22-like motif defines a novel antiapoptotic protein family
Author / Creator:Khoury, Chamel M ; Yang, Zhao ; Li, Xiao Yu ; Vignali, Marissa ; Fields, Stanley ; Greenwood, Michael T
Publisher:Oxford, UK: Oxford, UK : Blackwell Publishing Ltd
Journal title:FEMS yeast research, 2008-06, Vol.8 (4), p.540-563
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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
Author / Creator:Palikaras, Konstantinos ; Lionaki, Eirini ; Tavernarakis, Nektarios
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2018-09, Vol.20 (9), p.1013-1022
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FSP1 is a glutathione-independent ferroptosis suppressor
Author / Creator:Doll, Sebastian ; Freitas, Florencio Porto ; Shah, Ron ; Aldrovandi, Maceler ; da Silva, Milene Costa ; Ingold, Irina ; Goya Grocin, Andrea ; Xavier da Silva, Thamara Nishida ; Panzilius, Elena ; Scheel, Christina H. ; Mourão, André ; Buday, Katalin ; Sato, Mami ; Wanninger, Jonas ; Vignane, Thibaut ; Mohana, Vaishnavi ; Rehberg, Markus ; Flatley, Andrew ; Schepers, Aloys ; Kurz, Andreas ; White, Daniel ; Sauer, Markus ; Sattler, Michael ; Tate, Edward William ; Schmitz, Werner ; Schulze, Almut ; O’Donnell, Valerie ; Proneth, Bettina ; Popowicz, Grzegorz M. ; Pratt, Derek A. ; Angeli, José Pedro Friedmann ; Conrad, Marcus
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-11, Vol.575 (7784), p.693-698
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ArticlesPeer ReviewedFull Text
Phase separation of FSP1 promotes ferroptosis
Author / Creator:Nakamura, Toshitaka ; Hipp, Clara ; Santos Dias Mourão, André ; Borggräfe, Jan ; Aldrovandi, Maceler ; Henkelmann, Bernhard ; Wanninger, Jonas ; Mishima, Eikan ; Lytton, Elena ; Emler, David ; Proneth, Bettina ; Sattler, Michael ; Conrad, Marcus
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-07, Vol.619 (7969), p.371-377
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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death
Author / Creator:Orning, Pontus ; Weng, Dan ; Starheim, Kristian ; Ratner, Dmitry ; Best, Zachary ; Lee, Bettina ; Brooks, Alexandria ; Xia, Shiyu ; Wu, Hao ; Kelliher, Michelle A ; Berger, Scott B ; Gough, Peter J ; Bertin, John ; Proulx, Megan M ; Goguen, Jon D ; Kayagaki, Nobuhiko ; Fitzgerald, Katherine A ; Lien, Egil
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6418), p.1064-1069
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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
Author / Creator:Sarhan, Joseph ; Liu, Beiyun C. ; Muendlein, Hayley I. ; Li, Peng ; Nilson, Rachael ; Tang, Amy Y. ; Rongvaux, Anthony ; Bunnell, Stephen C. ; Shao, Feng ; Green, Douglas R. ; Poltorak, Alexander
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (46), p.E10888-E10897
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BCL-2 protein family: attractive targets for cancer therapy
Author / Creator:Kaloni, Deeksha ; Diepstraten, Sarah T ; Strasser, Andreas ; Kelly, Gemma L
Publisher:New York: Springer US
Journal title:Apoptosis (London), 2023-02, Vol.28 (1-2), p.20-38
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Author / Creator:He, Wan-ting ; Wan, Haoqiang ; Hu, Lichen ; Chen, Pengda ; Wang, Xin ; Huang, Zhe ; Yang, Zhang-Hua ; Zhong, Chuan-Qi ; Han, Jiahuai
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2015-12, Vol.25 (12), p.1285-1298
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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
Author / Creator:Rühl, Sebastian ; Shkarina, Kateryna ; Demarco, Benjamin ; Heilig, Rosalie ; Santos, José Carlos ; Broz, Petr
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6417), p.956-960
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Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
Author / Creator:Chen, Xin ; He, Wan-ting ; Hu, Lichen ; Li, Jingxian ; Fang, Yuan ; Wang, Xin ; Xu, Xiaozheng ; Wang, Zhuo ; Huang, Kai ; Han, Jiahuai
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2016-09, Vol.26 (9), p.1007-1020
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A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers
Author / Creator:Koppula, Pranavi ; Lei, Guang ; Zhang, Yilei ; Yan, Yuelong ; Mao, Chao ; Kondiparthi, Lavanya ; Shi, Jiejun ; Liu, Xiaoguang ; Horbath, Amber ; Das, Molina ; Li, Wei ; Poyurovsky, Masha V. ; Olszewski, Kellen ; Gan, Boyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.2206-16, Article 2206
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GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim

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Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism

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NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells

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Pseudomonas aeruginosa Type-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome

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Puma is required for p53-induced depletion of adult stem cells

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Pyruvate Kinase M2 Regulates Apoptosis of Intestinal Epithelial Cells in Crohn’s Disease

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Type I Interferon Drives Dendritic Cell Apoptosis via Multiple BH3-Only Proteins following Activation by PolyIC In Vivo

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Serine/Threonine Kinase 17A Is a Novel Candidate for Therapeutic Targeting in Glioblastoma

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Acute Myeloid Leukemia-Targeted Toxin Activates Both Apoptotic and Necroptotic Death Mechanisms

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TSC22-like motif defines a novel antiapoptotic protein family

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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

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FSP1 is a glutathione-independent ferroptosis suppressor

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Phase separation of FSP1 promotes ferroptosis

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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death

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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection

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BCL-2 protein family: attractive targets for cancer therapy

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

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Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis

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A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

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