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A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH
Author / Creator:Francque, Sven M ; Bedossa, Pierre ; Ratziu, Vlad ; Anstee, Quentin M ; Bugianesi, Elisabetta ; Sanyal, Arun J ; Loomba, Rohit ; Harrison, Stephen A ; Balabanska, Rozalina ; Mateva, Lyudmila ; Lanthier, Nicolas ; Alkhouri, Naim ; Moreno, Christophe ; Schattenberg, Jörn M ; Stefanova-Petrova, Diana ; Vonghia, Luisa ; Rouzier, Régine ; Guillaume, Maeva ; Hodge, Alexander ; Romero-Gómez, Manuel ; Huot-Marchand, Philippe ; Baudin, Martine ; Richard, Marie-Paule ; Abitbol, Jean-Louis ; Broqua, Pierre ; Junien, Jean-Louis ; Abdelmalek, Manal F
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2021-10, Vol.385 (17), p.1547-1558
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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
Author / Creator:Xu, Hong ; Di Antonio, Marco ; McKinney, Steven ; Mathew, Veena ; Ho, Brandon ; O’Neil, Nigel J. ; Santos, Nancy Dos ; Silvester, Jennifer ; Wei, Vivien ; Garcia, Jessica ; Kabeer, Farhia ; Lai, Daniel ; Soriano, Priscilla ; Banáth, Judit ; Chiu, Derek S. ; Yap, Damian ; Le, Daniel D. ; Ye, Frank B. ; Zhang, Anni ; Thu, Kelsie ; Soong, John ; Lin, Shu-chuan ; Tsai, Angela Hsin Chin ; Osako, Tomo ; Algara, Teresa ; Saunders, Darren N. ; Wong, Jason ; Xian, Jian ; Bally, Marcel B. ; Brenton, James D. ; Brown, Grant W. ; Shah, Sohrab P. ; Cescon, David ; Mak, Tak W. ; Caldas, Carlos ; Stirling, Peter C. ; Hieter, Phil ; Balasubramanian, Shankar ; Aparicio, Samuel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14432-18, Article 14432
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The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
Author / Creator:Quail, Daniela F. ; Bowman, Robert L. ; Akkari, Leila ; Quick, Marsha L. ; Schuhmacher, Alberto J. ; Huse, Jason T. ; Holland, Eric C. ; Sutton, James C. ; Joyce, Johanna A.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-05, Vol.352 (6288), p.952-952
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Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
Author / Creator:Smith, Catherine C. ; Wang, Qi ; Chin, Chen-Shan ; Salerno, Sara ; Damon, Lauren E. ; Levis, Mark J. ; Perl, Alexander E. ; Travers, Kevin J. ; Wang, Susana ; Hunt, Jeremy P. ; Zarrinkar, Patrick P. ; Schadt, Eric E. ; Kasarskis, Andrew ; Kuriyan, John ; Shah, Neil P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-05, Vol.485 (7397), p.260-263
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The Role of Bile Acids in Chronic Diarrhea
Author / Creator:Camilleri, Michael ; Vijayvargiya, Priya
Publisher:United States: Wolters Kluwer
Journal title:The American journal of gastroenterology, 2020-10, Vol.115 (10), p.1596-1603
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Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study
Author / Creator:Garcia-Ruiz, Pedro J ; Martinez Castrillo, Juan Carlos ; Alonso-Canovas, Araceli ; Herranz Barcenas, Antonio ; Vela, Lydia ; Sanchez Alonso, Pilar ; Mata, Marina ; Olmedilla Gonzalez, Nuria ; Mahillo Fernandez, Ignacio
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal of neurology, neurosurgery and psychiatry, 2014-08, Vol.85 (8), p.840-844
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Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial
Author / Creator:Schapira, Anthony HV, Prof ; McDermott, Michael P, Prof ; Barone, Paolo, Prof ; Comella, Cynthia L, Prof ; Albrecht, Stefan, MD ; Hsu, Helen H, MD ; Massey, Daniel H, MSc ; Mizuno, Yoshikuni, Prof ; Poewe, Werner, Prof ; Rascol, Olivier, Prof ; Marek, Kenneth, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2013-08, Vol.12 (8), p.747-755
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The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells
Author / Creator:Koh, Gene Ching Chiek ; Boushaki, Soraya ; Zhao, Salome Jingchen ; Pregnall, Andrew Marcel ; Sadiyah, Firas ; Badja, Cherif ; Memari, Yasin ; Georgakopoulos-Soares, Ilias ; Nik-Zainal, Serena
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2024-01, Vol.56 (1), p.23-26
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Modern Approaches to the Synthesis and Transformations of Practically Valuable Benzothiazole Derivatives
Author / Creator:Zhilitskaya, Larisa V ; Shainyan, Bagrat A ; Yarosh, Nina O
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-04, Vol.26 (8), p.2190
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Comparison of Pregabalin with Pramipexole for Restless Legs Syndrome
Author / Creator:Allen, Richard P ; Chen, Crystal ; Garcia-Borreguero, Diego ; Polo, Olli ; DuBrava, Sarah ; Miceli, Jeffrey ; Knapp, Lloyd ; Winkelman, John W
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-02, Vol.370 (7), p.621-631
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Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial
Author / Creator:Barone, Paolo, Prof ; Poewe, Werner, Prof ; Albrecht, Stefan, MD ; Debieuvre, Catherine, PharmD ; Massey, Dan, MSc ; Rascol, Olivier, Prof ; Tolosa, Eduardo, Prof ; Weintraub, Daniel, Prof
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2010-06, Vol.9 (6), p.573-580
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Quizartinib plus chemotherapy in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia (QuANTUM-First): a randomised, double-blind, placebo-controlled, phase...
Author / Creator:Erba, Harry P ; Montesinos, Pau ; Kim, Hee-Je ; Patkowska, Elżbieta ; Vrhovac, Radovan ; Žák, Pavel ; Wang, Po-Nan ; Mitov, Tsvetomir ; Hanyok, James ; Kamel, Yasser Mostafa ; Rohrbach, Jaime E Connolly ; Liu, Li ; Benzohra, Aziz ; Lesegretain, Arnaud ; Cortes, Jorge ; Perl, Alexander E ; Sekeres, Mikkael A ; Dombret, Hervé ; Amadori, Sergio ; Wang, Jianxiang ; Levis, Mark J ; Schlenk, Richard F
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2023-05, Vol.401 (10388), p.1571-1583
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ArticlesPeer ReviewedFull Text
Brain Dopamine–Serotonin Vesicular Transport Disease and Its Treatment
Author / Creator:Rilstone, Jennifer J ; Alkhater, Reem A ; Minassian, Berge A
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-02, Vol.368 (6), p.543-550
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Comparative efficacy and acceptability of antidepressants in Parkinson's disease: a network meta-analysis
Author / Creator:Liu, Jinling ; Dong, Jiangchuan ; Wang, Lei ; Su, Ying ; Yan, Peng ; Sun, Shenggang
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e76651-e76651
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Newly diagnosed AML: quizartinib improves OS
Author / Creator:Killock, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2023-08, Vol.20 (8), p.504-504
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Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial
Author / Creator:Poewe, Werner H, MD ; Rascol, Olivier, MD ; Quinn, Niall, MD ; Tolosa, Eduardo, MD ; Oertel, Wolfgang H, MD ; Martignoni, Emilia, MD ; Rupp, Markus, MD ; Boroojerdi, Babak, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2007-06, Vol.6 (6), p.513-520
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The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis
Author / Creator:Cudkowicz, Merit ; Bozik, Michael E ; Ingersoll, Evan W ; Miller, Robert ; Mitsumoto, Hiroshi ; Shefner, Jeremy ; Moore, Dan H ; Schoenfeld, David ; Mather, James L ; Archibald, Donald ; Sullivan, Mary ; Amburgey, Craig ; Moritz, Juliet ; Gribkoff, Valentin K
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2011-12, Vol.17 (12), p.1652-1656
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Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes
Author / Creator:Hosseini, Mona M. ; Kurtz, Stephen E. ; Abdelhamed, Sherif ; Mahmood, Shawn ; Davare, Monika A. ; Kaempf, Andy ; Elferich, Johannes ; McDermott, Jason E. ; Liu, Tao ; Payne, Samuel H. ; Shinde, Ujwal ; Rodland, Karin D. ; Mori, Motomi ; Druker, Brian J. ; Singer, Jack W. ; Agarwal, Anupriya
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2018-11, Vol.32 (11), p.2374-2387
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Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
Author / Creator:Theodoropoulos, Panayotis C ; Gonzales, Stephen S ; Winterton, Sarah E ; Rodriguez-Navas, Carlos ; McKnight, John S ; Morlock, Lorraine K ; Hanson, Jordan M ; Cross, Bethany ; Owen, Amy E ; Duan, Yingli ; Moreno, Jose R ; Lemoff, Andrew ; Mirzaei, Hamid ; Posner, Bruce A ; Williams, Noelle S ; Ready, Joseph M ; Nijhawan, Deepak
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2016-04, Vol.12 (4), p.218-225
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Evaluation of anti-glioma effects of benzothiazoles as efficient apoptosis inducers and DNA cleaving agents
Author / Creator:Sever, Belgin ; Ciftci, Halilibrahim
Publisher:New York: Springer US
Journal title:Molecular and cellular biochemistry, 2023-05, Vol.478 (5), p.1099-1108
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Showing 1 to 20 of 139 results

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A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH

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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

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The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

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Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

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The Role of Bile Acids in Chronic Diarrhea

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Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study

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Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial

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The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells

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Modern Approaches to the Synthesis and Transformations of Practically Valuable Benzothiazole Derivatives

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Comparison of Pregabalin with Pramipexole for Restless Legs Syndrome

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Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial

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Quizartinib plus chemotherapy in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia (QuANTUM-First): a randomised, double-blind, placebo-controlled, phase...

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Brain Dopamine–Serotonin Vesicular Transport Disease and Its Treatment

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Comparative efficacy and acceptability of antidepressants in Parkinson's disease: a network meta-analysis

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Newly diagnosed AML: quizartinib improves OS

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Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial

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The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis

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Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes

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Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

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Evaluation of anti-glioma effects of benzothiazoles as efficient apoptosis inducers and DNA cleaving agents

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