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Drug-Induced Conformational Dynamics of P-Glycoprotein Underlies the Transport of Camptothecin Analogs
Author / Creator:Mensah, Gershon A. K. ; Schaefer, Katherine G. ; Bartlett, Michael G. ; Roberts, Arthur G. ; King, Gavin M.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-11, Vol.24 (22), p.16058
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Lesser Toxicities of Belotecan in Patients with Small Cell Lung Cancer: A Retrospective Single-Center Study of Camptothecin Analogs
Author / Creator:Kim, Ju Ock ; Kim, Sun Young ; Lee, Jeong Eun ; Kim, Jin Hwan ; Park, Hee Sun ; Moon, Jae Young ; Park, Dong Il ; Park, Myoung Rin ; Park, Bo Mi ; Chung, Chae Uk ; Park, Yeon Hee ; Jung, Sung Soo
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Canadian respiratory journal, 2016-01, Vol.2016 (2016), p.1-8
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Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient
Author / Creator:Adams, David J. ; Wahl, Miriam L. ; Flowers, James L. ; Sen, Banalata ; Colvin, Michael ; Dewhirst, Mark W. ; Manikumar, Govindarajan ; Wani, Mansukh C.
Publisher:Berlin: Springer
Journal title:Cancer chemotherapy and pharmacology, 2006-02, Vol.57 (2), p.145-154
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Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer
Author / Creator:Modi, Shanu ; Jacot, William ; Yamashita, Toshinari ; Sohn, Joohyuk ; Vidal, Maria ; Tokunaga, Eriko ; Tsurutani, Junji ; Ueno, Naoto T. ; Prat, Aleix ; Chae, Yee Soo ; Lee, Keun Seok ; Niikura, Naoki ; Park, Yeon Hee ; Xu, Binghe ; Wang, Xiaojia ; Gil-Gil, Miguel ; Li, Wei ; Pierga, Jean-Yves ; Im, Seock-Ah ; Moore, Halle C.F. ; Rugo, Hope S. ; Yerushalmi, Rinat ; Zagouri, Flora ; Gombos, Andrea ; Kim, Sung-Bae ; Liu, Qiang ; Luo, Ting ; Saura, Cristina ; Schmid, Peter ; Sun, Tao ; Gambhire, Dhiraj ; Yung, Lotus ; Wang, Yibin ; Singh, Jasmeet ; Vitazka, Patrik ; Meinhardt, Gerold ; Harbeck, Nadia ; Cameron, David A.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-07, Vol.387 (1), p.9-20
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Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer
Author / Creator:Modi, Shanu ; Saura, Cristina ; Yamashita, Toshinari ; Park, Yeon Hee ; Kim, Sung-Bae ; Tamura, Kenji ; Andre, Fabrice ; Iwata, Hiroji ; Ito, Yoshinori ; Tsurutani, Junji ; Sohn, Joohyuk ; Denduluri, Neelima ; Perrin, Christophe ; Aogi, Kenjiro ; Tokunaga, Eriko ; Im, Seock-Ah ; Lee, Keun Seok ; Hurvitz, Sara A ; Cortes, Javier ; Lee, Caleb ; Chen, Shuquan ; Zhang, Lin ; Shahidi, Javad ; Yver, Antoine ; Krop, Ian
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-02, Vol.382 (7), p.610-621
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Early evaluation using a radiomic signature of unresectable hepatic metastases to predict outcome in patients with colorectal cancer treated with FOLFIRI and bevacizumab
Author / Creator:Dohan, Anthony ; Gallix, Benoit ; Guiu, Boris ; Le Malicot, Karine ; Soyer, Philippe ; Ghiringhelli, Francois ; Phelip, Jean-Marc ; Borel, Christian ; Faroux, Roger ; Seitz, Jean-Francois ; Jacquot, Stéphane ; Ben Abdelghani, Meher ; Khemissa-Akouz, Faiza ; Genet, Dominique ; Jouve, Jean Louis ; Rinaldi, Yves ; Texereau, Patrick ; Aparicio, Thomas ; Volet, Julien ; Kirscher, Sylvie ; Delique, Laurence ; Lepere, Céline ; Adenis, Antoine ; Hajbi, Farid El ; Locher, Christophe ; Denes, Sandrine Lavau ; Lecomte, Thierry ; Hautefeuille, Vincent ; Baconnier, Mathieu ; Michel, Pierre ; Blondin, Valérie ; Capitain, Olivier Joseph ; Queuniet, Anne-Marie ; Herve, Robert ; Mitry, Emmanuel ; Carola, Elisabeth ; Bedjaoui, Ahmed ; Douillard, Jean-yves ; Senellart, Hélène ; Hiret, Sandrine ; Lorgis, Véronique ; Vincent, Aude ; Ducreux, Michel ; Zrihen, Elie ; Follana, Philippe ; Borel, Christian ; Belletier, Christine ; Dewaele, François ; Dahan, Laétitia ; Duluc, Muriel ; Lafforgue, Béatrice ; Janssen, Eric ; Lepage, Côme ; Haineaux, Paul Arthur ; Audemar, Franck ; La Fouchardiere, Christelle De ; Bechade, Dominique ; Cany, Laurent ; Levache, Charles-Briac ; Barriere, Nicolas ; Bachet, Jean-Baptiste ; Mansourbakht, Touraj ; Conroy, Thierry ; Kaminsky, Marie-christine ; Cumin, Isabelle ; Egreteau, Joëlle ; Lamy, Régine ; Gasmi, Mohamed ; Luet, Dominique ; Couffon, Caroline ; Linot, Benjamin ; Guerin-Meyer, Véronique ; Nguyen, Suzanne ; Carreiro, Miguel ; Sarda, Corinne ; Lombard-Bohas, Catherine ; Forestier, Julien ; Salloum, Hatem ; Boussaha, Farah Zerouala ; Corina cornila, Jérôme Meunier ; Maillard, Christian ; Quentin, Vincent ; Giraud, Claire ; Vantelon, Jean-marie ; Bricquir, Yann Le ; Kikolski, Florence ; Goujon, Gaël ; Vergniol, Julien ; Pesque-penaud, Sophie ; Gouttebel, Marie-claude ; Gasnault, Laurent ; Danquechin, Etienne Dorval ; Gargot, Dany ; Robiche, Dominique Sevin ; Lagraniere, Stéfanie Oddou ; Wander, Lionel ; Mahamat, Abakar Abakar ; Martin, Philippe ; Boilleau-jolimoy, Geneviève ; Bidault, Anne Thirot
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2020-03, Vol.69 (3), p.531-539
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Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer
Author / Creator:Cortés, Javier ; Kim, Sung-Bae ; Chung, Wei-Pang ; Im, Seock-Ah ; Park, Yeon Hee ; Hegg, Roberto ; Kim, Min Hwan ; Tseng, Ling-Ming ; Petry, Vanessa ; Chung, Chi-Feng ; Iwata, Hiroji ; Hamilton, Erika ; Curigliano, Giuseppe ; Xu, Binghe ; Huang, Chiun-Sheng ; Kim, Jee Hyun ; Chiu, Joanne W.Y ; Pedrini, Jose Luiz ; Lee, Caleb ; Liu, Yali ; Cathcart, Jillian ; Bako, Emarjola ; Verma, Sunil ; Hurvitz, Sara A
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-03, Vol.386 (12), p.1143-1154
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Trastuzumab Deruxtecan in HER2-Mutant Non–Small-Cell Lung Cancer
Author / Creator:Li, Bob T ; Smit, Egbert F ; Goto, Yasushi ; Nakagawa, Kazuhiko ; Udagawa, Hibiki ; Mazières, Julien ; Nagasaka, Misako ; Bazhenova, Lyudmila ; Saltos, Andreas N ; Felip, Enriqueta ; Pacheco, Jose M ; Pérol, Maurice ; Paz-Ares, Luis ; Saxena, Kapil ; Shiga, Ryota ; Cheng, Yingkai ; Acharyya, Suddhasatta ; Vitazka, Patrik ; Shahidi, Javad ; Planchard, David ; Jänne, Pasi A
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-01, Vol.386 (3), p.241-251
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Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
Author / Creator:Bardia, Aditya ; Hurvitz, Sara A ; Tolaney, Sara M ; Loirat, Delphine ; Punie, Kevin ; Oliveira, Mafalda ; Brufsky, Adam ; Sardesai, Sagar D ; Kalinsky, Kevin ; Zelnak, Amelia B ; Weaver, Robert ; Traina, Tiffany ; Dalenc, Florence ; Aftimos, Philippe ; Lynce, Filipa ; Diab, Sami ; Cortés, Javier ; O’Shaughnessy, Joyce ; Diéras, Véronique ; Ferrario, Cristiano ; Schmid, Peter ; Carey, Lisa A ; Gianni, Luca ; Piccart, Martine J ; Loibl, Sibylle ; Goldenberg, David M ; Hong, Quan ; Olivo, Martin S ; Itri, Loretta M ; Rugo, Hope S
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2021-04, Vol.384 (16), p.1529-1541
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3D‐QSAR study of 20 (S)‐camptothecin analogs
Author / Creator:LU, Ai‐jun ; ZHANG, Zhen‐shan ; ZHENG, Ming‐yue ; ZOU, Han‐jun ; LUO, Xiao‐min ; JIANG, Hua‐liang
Publisher:Melbourne, Australia: Blackwell Publishing Asia
Journal title:Acta pharmacologica Sinica, 2007-02, Vol.28 (2), p.307-314
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Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer
Author / Creator:Shitara, Kohei ; Bang, Yung-Jue ; Iwasa, Satoru ; Sugimoto, Naotoshi ; Ryu, Min-Hee ; Sakai, Daisuke ; Chung, Hyun-Cheol ; Kawakami, Hisato ; Yabusaki, Hiroshi ; Lee, Jeeyun ; Saito, Kaku ; Kawaguchi, Yoshinori ; Kamio, Takahiro ; Kojima, Akihito ; Sugihara, Masahiro ; Yamaguchi, Kensei
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-06, Vol.382 (25), p.2419-2430
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FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis
Author / Creator:Suker, Mustafa, MD ; Beumer, Berend R ; Sadot, Eran, MD ; Marthey, Lysiane, MD ; Faris, Jason E, MD ; Mellon, Eric A, MD ; El-Rayes, Bassel F, Prof ; Wang-Gillam, Andrea, MD ; Lacy, Jill, Prof ; Hosein, Peter J, MD ; Moorcraft, Sing Yu, MD ; Conroy, Thierry, Prof ; Hohla, Florian, MD ; Allen, Peter, MD ; Taieb, Julien, Prof ; Hong, Theodore S, MD ; Shridhar, Ravi, MD ; Chau, Ian, MD ; van Eijck, Casper H, Prof ; Koerkamp, Bas Groot, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.801-810
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Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer
Author / Creator:Bardia, Aditya ; Mayer, Ingrid A ; Vahdat, Linda T ; Tolaney, Sara M ; Isakoff, Steven J ; Diamond, Jennifer R ; O’Shaughnessy, Joyce ; Moroose, Rebecca L ; Santin, Alessandro D ; Abramson, Vandana G ; Shah, Nikita C ; Rugo, Hope S ; Goldenberg, David M ; Sweidan, Ala M ; Iannone, Robert ; Washkowitz, Sarah ; Sharkey, Robert M ; Wegener, William A ; Kalinsky, Kevin
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-02, Vol.380 (8), p.741-751
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Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label,...
Author / Creator:Nywening, Timothy M, MD ; Wang-Gillam, Andrea, MD ; Sanford, Dominic E, MD ; Belt, Brian A, MA ; Panni, Roheena Z, MD ; Cusworth, Brian M, BA ; Toriola, Adetunji T, MD ; Nieman, Rebecca K, MS ; Worley, Lori A, BS ; Yano, Motoyo, MD ; Fowler, Kathryn J, MD ; Lockhart, A Craig, MD ; Suresh, Rama, MD ; Tan, Benjamin R, MD ; Lim, Kian-Huat, MD ; Fields, Ryan C, MD ; Strasberg, Steven M, Prof ; Hawkins, William G, Prof ; DeNardo, David G, PhD ; Goedegebuure, S Peter, PhD ; Linehan, David C, Dr Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-05, Vol.17 (5), p.651-662
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FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial
Author / Creator:Heinemann, Volker, Prof ; von Weikersthal, Ludwig Fischer, MD ; Decker, Thomas, MD ; Kiani, Alexander, Prof ; Vehling-Kaiser, Ursula, MD ; Al-Batran, Salah-Eddin, Prof ; Heintges, Tobias, Prof ; Lerchenmüller, Christian, MD ; Kahl, Christoph, MD ; Seipelt, Gernot, MD ; Kullmann, Frank, Prof ; Stauch, Martina, MD ; Scheithauer, Werner, Prof ; Hielscher, Jörg ; Scholz, Michael, MD ; Müller, Sebastian, MD ; Link, Hartmut, Prof ; Niederle, Norbert, Prof ; Rost, Andreas, MD ; Höffkes, Heinz-Gert, Prof ; Moehler, Markus, Prof ; Lindig, Reinhard U, MD ; Modest, Dominik P, MD ; Rossius, Lisa, MD ; Kirchner, Thomas, Prof ; Jung, Andreas, PhD ; Stintzing, Sebastian, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-09, Vol.15 (10), p.1065-1075
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Sacituzumab Govitecan: First Approval: Sacituzumab Govitecan: First Approval
Author / Creator:Syed, Yahiya Y.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2020-07, Vol.80 (10), p.1019-1025
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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, an...
Author / Creator:Tabernero, Josep, Dr ; Yoshino, Takayuki, MD ; Cohn, Allen Lee, MD ; Obermannova, Radka, MD ; Bodoky, Gyorgy, Prof ; Garcia-Carbonero, Rocio, MD ; Ciuleanu, Tudor-Eliade, Prof ; Portnoy, David C, MD ; Van Cutsem, Eric, Prof ; Grothey, Axel, MD ; Prausová, Jana, MD ; Garcia-Alfonso, Pilar, PhD ; Yamazaki, Kentaro, MD ; Clingan, Philip R, Prof ; Lonardi, Sara, MD ; Kim, Tae Won, Prof ; Simms, Lorinda, MS ; Chang, Shao-Chun, PhD ; Nasroulah, Federico, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-05, Vol.16 (5), p.499-508
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Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial
Author / Creator:Wang-Gillam, Andrea, MD ; Li, Chung-Pin, Prof ; Bodoky, György, Prof ; Dean, Andrew, MD ; Shan, Yan-Shen, Prof ; Jameson, Gayle, MSN ; Macarulla, Teresa, MD ; Lee, Kyung-Hun, MD ; Cunningham, David, Prof ; Blanc, Jean F, Prof ; Hubner, Richard A, PhD ; Chiu, Chang-Fang, Prof ; Schwartsmann, Gilberto, MD ; Siveke, Jens T, Prof ; Braiteh, Fadi, MD ; Moyo, Victor, MBBCh ; Belanger, Bruce, PhD ; Dhindsa, Navreet, DDS ; Bayever, Eliel, MBBCh ; Von Hoff, Daniel D, Prof ; Chen, Li-Tzong, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-02, Vol.387 (10018), p.545-557
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Trastuzumab Deruxtecan: First Approval
Author / Creator:Keam, Susan J.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2020-04, Vol.80 (5), p.501-508
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FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-lab...
Author / Creator:Stintzing, Sebastian, Dr ; Modest, Dominik P, MD ; Rossius, Lisa ; Lerch, Markus M, Prof ; von Weikersthal, Ludwig Fischer, MD ; Decker, Thomas, MD ; Kiani, Alexander, MD ; Vehling-Kaiser, Ursula, MD ; Al-Batran, Salah-Eddin, Prof ; Heintges, Tobias, MD ; Lerchenmüller, Christian, MD ; Kahl, Christoph, MD ; Seipelt, Gernot, MD ; Kullmann, Frank, MD ; Stauch, Martina, MD ; Scheithauer, Werner, Prof ; Held, Swantje, MSc ; Giessen-Jung, Clemens, MD ; Moehler, Markus, Prof ; Jagenburg, Andreas, MD ; Kirchner, Thomas, Prof ; Jung, Andreas, Prof ; Heinemann, Volker, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-10, Vol.17 (10), p.1426-1434
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Showing 1 to 20 of 2,352 results

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Drug-Induced Conformational Dynamics of P-Glycoprotein Underlies the Transport of Camptothecin Analogs

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Lesser Toxicities of Belotecan in Patients with Small Cell Lung Cancer: A Retrospective Single-Center Study of Camptothecin Analogs

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Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient

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Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer

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Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer

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Early evaluation using a radiomic signature of unresectable hepatic metastases to predict outcome in patients with colorectal cancer treated with FOLFIRI and bevacizumab

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Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer

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Trastuzumab Deruxtecan in HER2-Mutant Non–Small-Cell Lung Cancer

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Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer

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3D‐QSAR study of 20 (S)‐camptothecin analogs

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Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer

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FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis

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Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer

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Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label,...

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FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial

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Sacituzumab Govitecan: First Approval: Sacituzumab Govitecan: First Approval

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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, an...

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Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

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Trastuzumab Deruxtecan: First Approval

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FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-lab...

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