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ArticlesPeer ReviewedFull Text
Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics
Author / Creator:Liu, Guoxia ; Papa, Arianne ; Katchman, Alexander N. ; Zakharov, Sergey I. ; Roybal, Daniel ; Hennessey, Jessica A. ; Kushner, Jared ; Yang, Lin ; Chen, Bi-Xing ; Kushnir, Alexander ; Dangas, Katerina ; Gygi, Steven P. ; Pitt, Geoffrey S. ; Colecraft, Henry M. ; Ben-Johny, Manu ; Kalocsay, Marian ; Marx, Steven O.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-01, Vol.577 (7792), p.695-700
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Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect
Author / Creator:Ortuño, María José ; Robinson, Samuel T ; Subramanyam, Prakash ; Paone, Riccardo ; Huang, Yung-yu ; Guo, X Edward ; Colecraft, Henry M ; Mann, J John ; Ducy, Patricia
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-10, Vol.22 (10), p.1170-1179
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Structure and selectivity in bestrophin ion channels
Author / Creator:Yang, Tingting ; Liu, Qun ; Kloss, Brian ; Bruni, Renato ; Kalathur, Ravi C. ; Guo, Youzhong ; Kloppmann, Edda ; Rost, Burkhard ; Colecraft, Henry M. ; Hendrickson, Wayne A.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6207), p.355-359
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Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes
Author / Creator:Joseph, Leroy C. ; Barca, Emanuele ; Subramanyam, Prakash ; Komrowski, Michael ; Pajvani, Utpal ; Colecraft, Henry M. ; Hirano, Michio ; Morrow, John P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-01, Vol.11 (1), p.e0145750-e0145750
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Structural mechanism of ligand activation in human calcium-sensing receptor
Author / Creator:Geng, Yong ; Mosyak, Lidia ; Kurinov, Igor ; Zuo, Hao ; Sturchler, Emmanuel ; Cheng, Tat Cheung ; Subramanyam, Prakash ; Brown, Alice P ; Brennan, Sarah C ; Mun, Hee-chang ; Bush, Martin ; Chen, Yan ; Nguyen, Trang X ; Cao, Baohua ; Chang, Donald D ; Quick, Matthias ; Conigrave, Arthur D ; Colecraft, Henry M ; McDonald, Patricia ; Fan, Qing R
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2016-07, Vol.5 (2016)
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Distinct RGK GTPases Differentially Use α1- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit CaV1.2/CaV2.2 Channels
Author / Creator:Yang, Tingting ; Puckerin, Akil ; Colecraft, Henry M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-05, Vol.7 (5), p.e37079-e37079
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Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody
Author / Creator:Morgenstern, Travis J. ; Nirwan, Neha ; Hernández-Ochoa, Erick O. ; Bibollet, Hugo ; Choudhury, Papiya ; Laloudakis, Yianni D. ; Ben Johny, Manu ; Bannister, Roger A. ; Schneider, Martin F. ; Minor, Daniel L. ; Colecraft, Henry M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7556-7556, Article 7556
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Preassociated apocalmodulin mediates Ca²⁺-dependent sensitization of activation and inactivation of TMEM16A/16B Ca²⁺-gated Cl⁻ channels
Author / Creator:Yang, Tingting ; Hendrickson, Wayne A. ; Colecraft, Henry M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (51), p.18213-18218
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Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex
Author / Creator:Zou, Xinle ; Shanmugam, Sri Karthika ; Kanner, Scott A ; Sampson, Kevin J ; Kass, Robert S ; Colecraft, Henry M
Publisher:Cambridge: eLife Sciences Publications Ltd
Journal title:eLife, 2023-08, Vol.12
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Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M
Author / Creator:Poggio, Elena ; Vallese, Francesca ; Hartel, Andreas J. W. ; Morgenstern, Travis J. ; Kanner, Scott A. ; Rauh, Oliver ; Giamogante, Flavia ; Barazzuol, Lucia ; Shepard, Kenneth L. ; Colecraft, Henry M. ; Clarke, Oliver Biggs ; Brini, Marisa ; Calì, Tito
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2023-04, Vol.14 (4), p.297-297, Article 297
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A light-gated potassium channel for sustained neuronal inhibition
Author / Creator:Alberio, Laura ; Locarno, Andrea ; Saponaro, Andrea ; Romano, Edoardo ; Bercier, Valérie ; Albadri, Shahad ; Simeoni, Federica ; Moleri, Silvia ; Pelucchi, Silvia ; Porro, Alessandro ; Marcello, Elena ; Barsotti, Noemi ; Kukovetz, Kerri ; Boender, Arjen J. ; Contestabile, Andrea ; Luo, Shizhen ; Moutal, Aubin ; Ji, Yingshi ; Romani, Giulia ; Beltrame, Monica ; Del Bene, Filippo ; Di Luca, Monica ; Khanna, Rajesh ; Colecraft, Henry M. ; Pasqualetti, Massimo ; Thiel, Gerhard ; Tonini, Raffaella ; Moroni, Anna
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2018-11, Vol.15 (11), p.969-976
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BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules
Author / Creator:Hong, Ting-Ting ; Smyth, James W. ; Gao, Danchen ; Chu, Kevin Y. ; Vogan, Jacob M. ; Fong, Tina S. ; Jensen, Brian C. ; Colecraft, Henry M. ; Shaw, Robin M.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2010-02, Vol.8 (2), p.e1000312-e1000312
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Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
Author / Creator:Subramanyam, Prakash ; Chang, Donald D. ; Fang, Kun ; Xie, Wenjun ; Marks, Andrew R. ; Colecraft, Henry M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (38), p.15461-15466
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Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca2+ channels
Author / Creator:Liu, Nan ; Yang, Yaxiong ; Ge, Lin ; Liu, Min ; Colecraft, Henry M ; Liu, Xiaodong
Publisher:Cambridge: eLife Sciences Publications Ltd
Journal title:eLife, 2017-01, Vol.6
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Correction: Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes
Author / Creator:Joseph, Leroy C. ; Barca, Emanuele ; Subramanyam, Prakash ; Komrowski, Michael ; Pajvani, Utpal ; Colecraft, Henry M. ; Hirano, Michio ; Morrow, John P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-03, Vol.12 (3), p.e0174525-e0174525
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Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency
Author / Creator:González, Bryan J. ; Zhao, Haoquan ; Niu, Jacqueline ; Williams, Damian J. ; Lee, Jaeyop ; Goulbourne, Chris N. ; Xing, Yuan ; Wang, Yong ; Oberholzer, Jose ; Blumenkrantz, Maria H. ; Chen, Xiaojuan ; LeDuc, Charles A. ; Chung, Wendy K. ; Colecraft, Henry M. ; Gromada, Jesper ; Shen, Yufeng ; Goland, Robin S. ; Leibel, Rudolph L. ; Egli, Dieter
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2022-08, Vol.5 (1), p.779-779, Article 779
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Engineered Calmodulins Reveal the Unexpected Eminence of Ca2+Channel Inactivation in Controlling Heart Excitation
Author / Creator:Alseikhan, Badr A. ; DeMaria, Carla D. ; Colecraft, Henry M. ; Yue, David T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (26), p.17185-17190
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Targeted deubiquitination rescues distinct trafficking-deficient ion channelopathies
Author / Creator:Kanner, Scott A. ; Shuja, Zunaira ; Choudhury, Papiya ; Jain, Ananya ; Colecraft, Henry M.
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2020-12, Vol.17 (12), p.1245-1253
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A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary Ca V β subunits
Author / Creator:Morgenstern, Travis J ; Park, Jinseo ; Fan, Qing R ; Colecraft, Henry M
Publisher:England
Journal title:eLife, 2019-08, Vol.8
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Cardiac CaV1.2 channels require β subunits for β-adrenergic–mediated modulation but not trafficking
Author / Creator:Yang, Lin ; Katchman, Alexander ; Kushner, Jared ; Kushnir, Alexander ; Zakharov, Sergey I. ; Chen, Bi-xing ; Shuja, Zunaira ; Subramanyam, Prakash ; Liu, Guoxia ; Papa, Arianne ; Roybal, Daniel ; Pitt, Geoffrey S. ; Colecraft, Henry M. ; Marx, Steven O.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-02, Vol.129 (2), p.647-658
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Showing 1 to 20 of 58 results

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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics

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Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect

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Structure and selectivity in bestrophin ion channels

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Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

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Structural mechanism of ligand activation in human calcium-sensing receptor

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Distinct RGK GTPases Differentially Use α1- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit CaV1.2/CaV2.2 Channels

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Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody

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Preassociated apocalmodulin mediates Ca²⁺-dependent sensitization of activation and inactivation of TMEM16A/16B Ca²⁺-gated Cl⁻ channels

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Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex

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Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M

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A light-gated potassium channel for sustained neuronal inhibition

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BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

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Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing

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Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca2+ channels

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Correction: Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

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Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency

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Engineered Calmodulins Reveal the Unexpected Eminence of Ca2+Channel Inactivation in Controlling Heart Excitation

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Targeted deubiquitination rescues distinct trafficking-deficient ion channelopathies

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A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary Ca V β subunits

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Cardiac CaV1.2 channels require β subunits for β-adrenergic–mediated modulation but not trafficking

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