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ArticlesPeer ReviewedFull Text
Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport
Author / Creator:Kosyna, Friederike K ; Depping, Reinhard
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2018-11, Vol.7 (11), p.221
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Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing
Author / Creator:Depping, Reinhard ; Jelkmann, Wolfgang ; Kosyna, Friederike Katharina
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of molecular medicine (Berlin, Germany), 2015-06, Vol.93 (6), p.599-608
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ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells
Author / Creator:Mandl, Markus ; Depping, Reinhard
Publisher:England: BioMed Central
Journal title:Cancer cell international, 2017-08, Vol.17 (1), p.77-77, Article 77
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Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity
Author / Creator:von Fallois, Moritz ; Kosyna, Friederike Katharina ; Mandl, Markus ; Landesman, Yosef ; Dunst, Jürgen ; Depping, Reinhard
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2021-07, Vol.147 (7), p.2025-2033
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Distinguishing the impact of distinct obstructive sleep apnea syndrome (OSAS) and obesity related factors on human monocyte subsets
Author / Creator:Pries, Ralph ; Kosyna, Friederike Katharina ; Depping, Reinhard ; Plötze-Martin, Kirstin ; Lange, Christian ; Meyhöfer, Svenja ; Meyhöfer, Sebastian M. ; Marquardt, Jens U. ; Bruchhage, Karl-Ludwig ; Steffen, Armin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-01, Vol.14 (1), p.340-340, Article 340
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Type 2-like polarization and elevated CXCL4 secretion of monocyte derived macrophages upon internalization of plasma-derived exosomes from head and neck cancer patients
Author / Creator:Theodoraki, Marie-Nicole ; Huber, Diana ; Hofmann, Linda ; Werner, Lotte ; Idel, Christian ; Fleckner, Jonas ; Plötze-Martin, Kirstin ; Schütt, Lutz ; Brunner, Cornelia ; Depping, Reinhard ; Hoffmann, Thomas K ; Bruchhage, Karl-Ludwig ; Pries, Ralph
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2024-09, Vol.24 (1), p.1173-12, Article 1173
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Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth
Author / Creator:Ménard, Marie ; Costechareyre, Clélia ; Ichim, Gabriel ; Blachier, Jonathan ; Neves, David ; Jarrosson-Wuilleme, Loraine ; Depping, Reinhard ; Koster, Jan ; Saintigny, Pierre ; Mehlen, Patrick ; Tauszig-Delamasure, Servane
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2018-05, Vol.16 (5), p.e2002912-e2002912
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ArticlesPeer ReviewedFull Text
miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia
Author / Creator:Ozkurt, Mete ; Hellwig-Bürgel, Thomas ; Depping, Reinhard ; Kadabere, Selda ; Ozyurt, Rumeysa ; Karadag, Abdullah ; Erkasap, Nilüfer
Publisher:New York: Hindawi
Journal title:International journal of endocrinology, 2021, Vol.2021, p.1-10
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Notch1 signaling is mediated by importins alpha 3, 4, and 7
Author / Creator:Huenniger, Kerstin ; Krämer, Andreas ; Soom, Malle ; Chang, Iree ; Köhler, Matthias ; Depping, Reinhard ; Kehlenbach, Ralph H ; Kaether, Christoph
Publisher:Basel: Basel : SP Birkhäuser Verlag Basel
Journal title:Cellular and molecular life sciences : CMLS, 2010-09, Vol.67 (18), p.3187-3196
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The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment
Author / Creator:Mandl, Markus ; Lieberum, Maria- Katharina ; Dunst, Juergen ; Depping, Reinhard
Publisher:England: BioMed Central Ltd
Journal title:Radiation oncology (London, England), 2015-11, Vol.10 (230), p.229-229, Article 229
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Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis by Maintaining Hepatocyte Nuclear Factor-4α Expression
Author / Creator:Sun, Wenwen ; Kosyna, Friederike Katharina ; Jelkmann, Wolfgang ; Depping, Reinhard
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2015-01, Vol.37 (6), p.2257-2264
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ArticlesPeer ReviewedFull Text
Hypoxia-inducible aryl hydrocarbon receptor nuclear translocator (ARNT) (HIF-1β): is it a rare exception?
Author / Creator:Mandl, Markus ; Depping, Reinhard
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2014-05, Vol.20 (1), p.215-220
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ArticlesPeer ReviewedFull Text
1H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines—an effect to be considered in cell culture experiments
Author / Creator:Depping, Reinhard ; Seeger, Karsten
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2019-02, Vol.411 (4), p.797-802
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ArticlesPeer ReviewedFull Text
sup.1H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines-an effect to be considered in cell culture experiments
Author / Creator:Depping, Reinhard ; Seeger, Karsten
Publisher:Springer
Journal title:Analytical and bioanalytical chemistry, 2019-02, Vol.411 (4), p.797
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Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes
Author / Creator:Jagodzinski, Nele ; Leichtle, Anke ; Depping, Reinhard ; Plötze-Martin, Kirstin ; Hakim, Samer G. ; Bruchhage, Karl-Ludwig ; Pries, Ralph
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-04, Vol.15 (1), p.12126
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ArticlesPeer ReviewedFull Text
1 H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines-an effect to be considered in cell culture experiments
Author / Creator:Depping, Reinhard ; Seeger, Karsten
Publisher:Germany
Journal title:Analytical and bioanalytical chemistry, 2019-02, Vol.411 (4), p.797
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Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3
Author / Creator:Sowa, Anna Sergeevna ; Martin, Elodie ; Martins, Inês Morgado ; Schmidt, Jana ; Depping, Reinhard ; Weber, Jonasz Jeremiasz ; Rother, Franziska ; Hartmann, Enno ; Bader, Michael ; Riess, Olaf ; Tricoire, Hervé ; Schmidt, Thorsten
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (11), p.E2624-E2633
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ArticlesPeer ReviewedFull Text
Curcumin Decreases Survival of Hep3B Liver and MCF-7 Breast Cancer Cells: The Role of HIF
Author / Creator:Ströfer, Mareike ; Jelkmann, Wolfgang ; Depping, Reinhard
Publisher:Munchen: Urban and Vogel
Journal title:Strahlentherapie und Onkologie, 2011-07, Vol.187 (7), p.393-400
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Curcumin Decreases Survival of Hep3B Liver and MCF-7 Breast Cancer Cells
Author / Creator:Ströfer, Mareike ; Jelkmann, Wolfgang ; Depping, Reinhard
Publisher:Heidelberg: Springer Nature B.V
Journal title:Strahlentherapie und Onkologie, 2011-07, Vol.187 (7), p.393
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The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells
Author / Creator:Depping, Reinhard ; von Fallois, Moritz ; Landesman, Yosef ; Kosyna, Friederike Katharina
Publisher:New Zealand: Dove Medical Press Limited
Journal title:OncoTargets and therapy, 2019-10, Vol.12, p.8387-8399
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Showing 1 to 20 of 33 results

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Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport

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Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing

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ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells

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Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity

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Distinguishing the impact of distinct obstructive sleep apnea syndrome (OSAS) and obesity related factors on human monocyte subsets

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Type 2-like polarization and elevated CXCL4 secretion of monocyte derived macrophages upon internalization of plasma-derived exosomes from head and neck cancer patients

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Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth

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miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia

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Notch1 signaling is mediated by importins alpha 3, 4, and 7

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The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment

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Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis by Maintaining Hepatocyte Nuclear Factor-4α Expression

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Hypoxia-inducible aryl hydrocarbon receptor nuclear translocator (ARNT) (HIF-1β): is it a rare exception?

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1H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines—an effect to be considered in cell culture experiments

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sup.1H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines-an effect to be considered in cell culture experiments

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Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes

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1 H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines-an effect to be considered in cell culture experiments

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Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3

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Curcumin Decreases Survival of Hep3B Liver and MCF-7 Breast Cancer Cells: The Role of HIF

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Curcumin Decreases Survival of Hep3B Liver and MCF-7 Breast Cancer Cells

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The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells

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