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ArticlesPeer ReviewedFull Text
Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
Author / Creator:Fitz, Nicholas F. ; Nam, Kyong Nyon ; Wolfe, Cody M. ; Letronne, Florent ; Playso, Brittany E. ; Iordanova, Bistra E. ; Kozai, Takashi D. Y. ; Biedrzycki, Richard J. ; Kagan, Valerian E. ; Tyurina, Yulia Y. ; Han, Xianlin ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3416-18, Article 3416
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APOEε4 and risk of Alzheimer’s disease – time to move forward
Author / Creator:Lefterov, Iliya ; Fitz, Nicholas F. ; Lu, Yi ; Koldamova, Radosveta
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2023-05, Vol.17, p.1195724-1195724
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Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice
Author / Creator:Fitz, Nicholas F. ; Wolfe, Cody M. ; Playso, Brittany E. ; Biedrzycki, Richard J. ; Lu, Yi ; Nam, Kyong Nyon ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2020-07, Vol.15 (1), p.41-21, Article 41
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Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice
Author / Creator:Nam, Kyong Nyon ; Mounier, Anais ; Wolfe, Cody M. ; Fitz, Nicholas F. ; Carter, Alexis Y. ; Castranio, Emilie L. ; Kamboh, Hafsa I. ; Reeves, Valerie L. ; Wang, Jianing ; Han, Xianlin ; Schug, Jonathan ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-06, Vol.7 (1), p.4307-13, Article 4307
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APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain
Author / Creator:Lefterov, Iliya ; Wolfe, Cody M. ; Fitz, Nicholas F. ; Nam, Kyong Nyon ; Letronne, Florent ; Biedrzycki, Richard J. ; Kofler, Julia ; Han, Xianlin ; Wang, Jianing ; Schug, Jonathan ; Koldamova, Radosveta
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2019-12, Vol.11 (1), p.113-16, Article 113
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Genome-Wide Alteration of Histone H3K9 Acetylation Pattern in Mouse Offspring Prenatally Exposed to Arsenic
Author / Creator:Cronican, Andrea A. ; Fitz, Nicholas F. ; Carter, Alexis ; Saleem, Muzamil ; Shiva, Sruti ; Barchowsky, Aaron ; Koldamova, Radosveta ; Schug, Jonathan ; Lefterov, Iliya
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-02, Vol.8 (2), p.e53478
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Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice
Author / Creator:Carter, Alexis Y. ; Letronne, Florent ; Fitz, Nicholas F. ; Mounier, Anais ; Wolfe, Cody M. ; Nam, Kyong Nyon ; Reeves, Valerie L. ; Kamboh, Hafsa ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-02, Vol.12 (2), p.e0172161-e0172161
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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives
Author / Creator:Wolfe, Cody M. ; Fitz, Nicholas F. ; Nam, Kyong Nyon ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2019-01, Vol.20 (1), p.81
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ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms
Author / Creator:Castranio, Emilie L. ; Wolfe, Cody M. ; Nam, Kyong Nyon ; Letronne, Florent ; Fitz, Nicholas F. ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2018-07, Vol.6 (1), p.69-13, Article 69
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Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”
Author / Creator:Fitz, Nicholas F. ; Cronican, Andrea A. ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:United States
Journal title:Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924
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Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice
Author / Creator:Fitz, Nicholas F. ; Sahu, Amrita ; Lu, Yi ; Ambrosio, Fabrisia ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-08, Vol.24 (16), p.12550
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Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles
Author / Creator:Sahu, Amrita ; Clemens, Zachary J ; Shinde, Sunita N ; Sivakumar, Sruthi ; Pius, Abish ; Bhatia, Ankit ; Picciolini, Silvia ; Carlomagno, Cristiano ; Gualerzi, Alice ; Bedoni, Marzia ; Van Houten, Bennett ; Lovalekar, Mita ; Fitz, Nicholas F ; Lefterov, Iliya ; Barchowsky, Aaron ; Koldamova, Radosveta ; Ambrosio, Fabrisia
Publisher:United States: Nature Publishing Group
Journal title:Nature aging, 2021-12, Vol.1 (12), p.1148-1161
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RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers
Author / Creator:Nam, Kyong Nyon ; Mounier, Anais ; Fitz, Nicholas F. ; Wolfe, Cody ; Schug, Jonathan ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-04, Vol.6 (1), p.24048-24048, Article 24048
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ArticlesPeer ReviewedFull Text
Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles
Author / Creator:Sahu, Amrita ; Clemens, Zachary J. ; Shinde, Sunita N. ; Sivakumar, Sruthi ; Pius, Abish ; Bhatia, Ankit ; Picciolini, Silvia ; Carlomagno, Cristiano ; Gualerzi, Alice ; Bedoni, Marzia ; Van Houten, Bennett ; Lovalekar, Mita ; Fitz, Nicholas F. ; Lefterov, Iliya ; Barchowsky, Aaron ; Koldamova, Radosveta ; Ambrosio, Fabrisia
Journal title:Nature aging, 2021-12, Vol.1 (12), p.1148-1161
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The integration of epigenomic and transcriptomic sequencing data reveals cell‐specific Bexarotene‐induced transcriptional activity in APP/PS1 mouse brain
Author / Creator:Lu, Yi ; Saibro‐Girardi, Carolina ; Fitz, Nicholas F ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S8), p.n/a
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Comment on "ApoE-Directed Therapeutics Rapidly Clear [beta]-Amyloid and Reverse Deficits in AD Mouse Models"
Author / Creator:Fitz, Nicholas F ; Cronican, Andrea A ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:Washington: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924
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ArticlesPeer ReviewedFull Text
The Role of APOE and TREM2 in Alzheimer's Disease-Current Understanding and Perspectives
Author / Creator:Wolfe, Cody M ; Fitz, Nicholas F ; Nam, Kyong Nyon ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:Switzerland
Journal title:International journal of molecular sciences, 2018-12, Vol.20 (1)
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RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of A[beta] oligomers
Author / Creator:Nam, Kyong Nyon ; Mounier, Anais ; Fitz, Nicholas F ; Wolfe, Cody ; Schug, Jonathan ; Lefterov, Iliya ; Koldamova, Radosveta
Publisher:London: Nature Publishing Group
Journal title:Scientific reports, 2016-04, Vol.6, p.24048
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Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease

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APOEε4 and risk of Alzheimer’s disease – time to move forward

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Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

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Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

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APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

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Genome-Wide Alteration of Histone H3K9 Acetylation Pattern in Mouse Offspring Prenatally Exposed to Arsenic

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Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

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ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

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Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”

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Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

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Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

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RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

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Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

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The integration of epigenomic and transcriptomic sequencing data reveals cell‐specific Bexarotene‐induced transcriptional activity in APP/PS1 mouse brain

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Comment on "ApoE-Directed Therapeutics Rapidly Clear [beta]-Amyloid and Reverse Deficits in AD Mouse Models"

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The Role of APOE and TREM2 in Alzheimer's Disease-Current Understanding and Perspectives

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RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of A[beta] oligomers

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