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1,114 results for Lyases+-+chemistry

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ArticlesPeer ReviewedFull Text
De novo NAD+ synthesis enhances mitochondrial function and improves health
Author / Creator:Katsyuba, Elena ; Mottis, Adrienne ; Zietak, Marika ; De Franco, Francesca ; van der Velpen, Vera ; Gariani, Karim ; Ryu, Dongryeol ; Cialabrini, Lucia ; Matilainen, Olli ; Liscio, Paride ; Giacchè, Nicola ; Stokar-Regenscheit, Nadine ; Legouis, David ; de Seigneux, Sophie ; Ivanisevic, Julijana ; Raffaelli, Nadia ; Schoonjans, Kristina ; Pellicciari, Roberto ; Auwerx, Johan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-11, Vol.563 (7731), p.354-359
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An algal photoenzyme converts fatty acids to hydrocarbons
Author / Creator:Sorigué, Damien ; Légeret, Bertrand ; Cuiné, Stéphan ; Blangy, Stéphanie ; Moulin, Solène ; Billon, Emmanuelle ; Richaud, Pierre ; Brugière, Sabine ; Couté, Yohann ; Nurizzo, Didier ; Müller, Pavel ; Brettel, Klaus ; Pignol, David ; Arnoux, Pascal ; Li-Beisson, Yonghua ; Peltier, Gilles ; Beisson, Fred
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-09, Vol.357 (6354), p.903-907
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Sustained enzymatic activity and flow in crowded protein droplets
Author / Creator:Testa, Andrea ; Dindo, Mirco ; Rebane, Aleksander A. ; Nasouri, Babak ; Style, Robert W. ; Golestanian, Ramin ; Dufresne, Eric R. ; Laurino, Paola
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6293-8, Article 6293
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Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals
Author / Creator:Suzuki, Yuta ; Cardone, Giovanni ; Restrepo, David ; Zavattieri, Pablo D. ; Baker, Timothy S. ; Tezcan, F. Akif
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-05, Vol.533 (7603), p.369-373
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FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis
Author / Creator:Gao, Lei ; Su, Cong ; Du, Xiaoxia ; Wang, Ruishan ; Chen, Shuming ; Zhou, Yu ; Liu, Chengwei ; Liu, Xiaojing ; Tian, Runze ; Zhang, Liyun ; Xie, Kebo ; Chen, She ; Guo, Qianqian ; Guo, Lanping ; Hano, Yoshio ; Shimazaki, Manabu ; Minami, Atsushi ; Oikawa, Hideaki ; Huang, Niu ; Houk, K. N. ; Huang, Luqi ; Dai, Jungui ; Lei, Xiaoguang
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2020-07, Vol.12 (7), p.620-628
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An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
Author / Creator:Shon, D. Judy ; Malaker, Stacy A. ; Pedram, Kayvon ; Yang, Emily ; Krishnan, Venkatesh ; Dorigo, Oliver ; Bertozzi, Carolyn R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21299-21307
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Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action
Author / Creator:Yan, Yan ; Liu, Qikun ; Zang, Xin ; Yuan, Shuguang ; Bat-Erdene, Undramaa ; Nguyen, Calvin ; Gan, Jianhua ; Zhou, Jiahai ; Jacobsen, Steven E. ; Tang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-07, Vol.559 (7714), p.415-418
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Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome
Author / Creator:Li, Xiaoyu ; Zhu, Ping ; Ma, Shiqing ; Song, Jinghui ; Bai, Jinyi ; Sun, Fangfang ; Yi, Chengqi
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2015-08, Vol.11 (8), p.592-597
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Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases
Author / Creator:Jenner, Matthew ; Kosol, Simone ; Griffiths, Daniel ; Prasongpholchai, Panward ; Manzi, Lucio ; Barrow, Andrew S ; Moses, John E ; Oldham, Neil J ; Lewandowski, Józef R ; Challis, Gregory L
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2018-03, Vol.14 (3), p.270-275
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ArticlesPeer ReviewedFull Text
New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition
Author / Creator:Payne, Karl A. P. ; White, Mark D. ; Fisher, Karl ; Khara, Basile ; Bailey, Samuel S. ; Parker, David ; Rattray, Nicholas J. W. ; Trivedi, Drupad K. ; Goodacre, Royston ; Beveridge, Rebecca ; Barran, Perdita ; Rigby, Stephen E. J. ; Scrutton, Nigel S. ; Hay, Sam ; Leys, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-06, Vol.522 (7557), p.497-501
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The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation
Author / Creator:Chun, Hye Lin ; Lee, So Yeon ; Kim, Ki-Hwa ; Lee, Chang Sup ; Oh, Tae-Jin ; Park, Hyun Ho
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-12, Vol.15 (12), p.e0242383-e0242383
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ArticlesPeer ReviewedFull Text
Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy
Author / Creator:Rolando, Monica ; Escoll, Pedro ; Nora, Tamara ; Botti, Joëlle ; Boitez, Valérie ; Bedia, Carmen ; Daniels, Craig ; Abraham, Gilu ; Stogios, Peter J. ; Skarina, Tatiana ; Christophe, Charlotte ; Dervins-Ravault, Delphine ; Cazalet, Christel ; Hilbi, Hubert ; Rupasinghe, Thusitha W. T. ; Tull, Dedreia ; McConville, Malcolm J. ; Ong, Sze Ying ; Hartland, Elizabeth L. ; Codogno, Patrice ; Levade, Thierry ; Naderer, Thomas ; Savchenko, Alexei ; Buchrieser, Carmen
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1901-1906
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ArticlesPeer ReviewedFull Text
FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants
Author / Creator:Bednar, David ; Beerens, Koen ; Sebestova, Eva ; Bendl, Jaroslav ; Khare, Sagar ; Chaloupkova, Radka ; Prokop, Zbynek ; Brezovsky, Jan ; Baker, David ; Damborsky, Jiri
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2015-11, Vol.11 (11), p.e1004556
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ArticlesPeer ReviewedFull Text
Evolution of a designed retro-aldolase leads to complete active site remodeling
Author / Creator:Giger, Lars ; Caner, Sami ; Obexer, Richard ; Kast, Peter ; Baker, David ; Ban, Nenad ; Hilvert, Donald
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2013-08, Vol.9 (8), p.494-498
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ArticlesPeer ReviewedFull Text
Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase
Author / Creator:Xu, Jian ; Fan, Jiajie ; Lou, Yujiao ; Xu, Weihua ; Wang, Zhiguo ; Li, Danyang ; Zhou, Haonan ; Lin, Xianfu ; Wu, Qi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3983-10, Article 3983
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Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions
Author / Creator:Cory, Seth A. ; Van Vranken, Jonathan G. ; Brignole, Edward J. ; Patra, Shachin ; Winge, Dennis R. ; Drennan, Catherine L. ; Rutter, Jared ; Barondeau, David P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.E5325-E5334
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De Novo Computational Design of Retro-Aldol Enzymes
Author / Creator:Jiang, Lin ; Althoff, Eric A. ; Clemente, Fernando R. ; Doyle, Lindsey ; Röthlisberger, Daniela ; Zanghellini, Alexandre ; Gallaher, Jasmine L. ; Betker, Jamie L. ; Tanaka, Fujie ; Barbas, Carlos F. ; Hilvert, Donald ; Houk, Kendall N. ; Stoddard, Barry L. ; Baker, David
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5868), p.1387-1391
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Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis
Author / Creator:Chen, Fangfang ; Lukat, Peer ; Iqbal, Azeem Ahmed ; Saile, Kyrill ; Kaever, Volkhard ; vandenHeuvel, Joop ; Blankenfeldt, Wulf ; Büssow, Konrad ; Pessler, Frank
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (41), p.20644-20654
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Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB
Author / Creator:Ortega, Manuel A. ; Hao, Yue ; Zhang, Qi ; Walker, Mark C. ; van der Donk, Wilfred A. ; Nair, Satish K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-01, Vol.517 (7535), p.509-512
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How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans
Author / Creator:Cartmell, Alan ; Lowe, Elisabeth C. ; Baslé, Arnaud ; Firbank, Susan J. ; Ndeh, Didier A. ; Murray, Heath ; Terrapon, Nicolas ; Lombard, Vincent ; Henrissat, Bernard ; Turnbull, Jeremy E. ; Czjzek, Mirjam ; Gilbert, Harry J. ; Bolam, David N.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.7037-7042
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Showing 1 to 20 of 1,114 results

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De novo NAD+ synthesis enhances mitochondrial function and improves health

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An algal photoenzyme converts fatty acids to hydrocarbons

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Sustained enzymatic activity and flow in crowded protein droplets

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Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals

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FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis

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An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins

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Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action

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Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome

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Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases

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New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition

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The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation

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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

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FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

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Evolution of a designed retro-aldolase leads to complete active site remodeling

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Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase

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Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions

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De Novo Computational Design of Retro-Aldol Enzymes

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Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis

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Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB

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How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans

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