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Prophylaxe von Übelkeit und Erbrechen nach medikamentöser Tumortherapie
Author / Creator:Link, Hartmut
Publisher:Heidelberg: Springer Nature B.V
Journal title:Urologe. Ausgabe A, 2022-06, Vol.61 (6), p.667-680
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ArticlesPeer ReviewedFull Text
Substance P and pain chronicity
Author / Creator:Zieglgänsberger, W.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cell and tissue research, 2019-01, Vol.375 (1), p.227-241
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Selective G protein signaling driven by substance P–neurokinin receptor dynamics
Author / Creator:Harris, Julian A. ; Faust, Bryan ; Gondin, Arisbel B. ; Dämgen, Marc André ; Suomivuori, Carl-Mikael ; Veldhuis, Nicholas A. ; Cheng, Yifan ; Dror, Ron O. ; Thal, David M. ; Manglik, Aashish
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2022-01, Vol.18 (1), p.109-115
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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain
Author / Creator:Ramírez-García, Paulina D. ; Retamal, Jeffri S. ; Shenoy, Priyank ; Imlach, Wendy ; Sykes, Matthew ; Truong, Nghia ; Constandil, Luis ; Pelissier, Teresa ; Nowell, Cameron J. ; Khor, Song Y. ; Layani, Louis M. ; Lumb, Chris ; Poole, Daniel P. ; Lieu, TinaMarie ; Stewart, Gregory D. ; Mai, Quynh N. ; Jensen, Dane D. ; Latorre, Rocco ; Scheff, Nicole N. ; Schmidt, Brian L. ; Quinn, John F. ; Whittaker, Michael R. ; Veldhuis, Nicholas A. ; Davis, Thomas P. ; Bunnett, Nigel W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2019-12, Vol.14 (12), p.1150-1159
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Clinical presentation, management, and pathophysiology of neuropathic itch
Author / Creator:Steinhoff, Martin ; Schmelz, Martin ; Szabó, Imre Lőrinc ; Oaklander, Anne Louise
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2018-08, Vol.17 (8), p.709-720
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SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors
Author / Creator:Taracanova, Alexandra ; Alevizos, Mihail ; Karagkouni, Anna ; Weng, Zuiy ; Norwitz, Errol ; Conti, Pio ; Leeman, Susan E. ; Theoharides, Theoharis C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (20), p.E4002-E4009
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Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials
Author / Creator:Gavriatopoulou, Maria ; Chari, Ajai ; Chen, Christine ; Bahlis, Nizar ; Vogl, Dan T. ; Jakubowiak, Andrzej ; Dingli, David ; Cornell, Robert F. ; Hofmeister, Craig C. ; Siegel, David ; Berdeja, Jesus G. ; Reece, Donna ; White, Darrell ; Lentzsch, Suzanne ; Gasparetto, Cristina ; Huff, Carol Ann ; Jagannath, Sundar ; Baz, Rachid ; Nooka, Ajay K. ; Richter, Joshua ; Abonour, Rafat ; Parker, Terri L. ; Yee, Andrew J. ; Moreau, Philippe ; Lonial, Sagar ; Tuchman, Sascha ; Weisel, Katja C. ; Mohty, Mohamad ; Choquet, Sylvain ; Unger, T. J. ; Li, Kai ; Chai, Yi ; Li, Lingling ; Shah, Jatin ; Shacham, Sharon ; Kauffman, Michael G. ; Dimopoulos, Meletios Athanasios
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-09, Vol.34 (9), p.2430-2440
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The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury
Author / Creator:Sorby-Adams, Annabel J ; Marcoionni, Amanda M ; Dempsey, Eden R ; Woenig, Joshua A ; Turner, Renée J
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-08, Vol.18 (8), p.1788
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ArticlesPeer ReviewedFull Text
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation
Author / Creator:Manion, John ; Musser, Melissa A ; Kuziel, Gavin A ; Liu, Min ; Shepherd, Amy ; Wang, Siyu ; Lee, Pyung-Gang ; Zhao, Leo ; Zhang, Jie ; Marreddy, Ravi K R ; Goldsmith, Jeffrey D ; Yuan, Ke ; Hurdle, Julian G ; Gerhard, Ralf ; Jin, Rongsheng ; Rakoff-Nahoum, Seth ; Rao, Meenakshi ; Dong, Min
Publisher:England: Nature Publishing Group
Journal title:Nature (London), 2023-10, Vol.622 (7983), p.611-618
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ArticlesPeer ReviewedFull Text
Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload
Author / Creator:Ge, Chentao ; Huang, Hemiao ; Huang, Feiyan ; Yang, Tianxin ; Zhang, Tengfei ; Wu, Hongzhang ; Zhou, Hanwei ; Chen, Qi ; Shi, Yue ; Sun, Yanfang ; Liu, Liangjue ; Wang, Xi ; Pearson, Richard B. ; Cao, Yihai ; Kang, Jian ; Fu, Caiyun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (39), p.19635-19645
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ArticlesPeer ReviewedFull Text
Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
Author / Creator:Chen, Shuanghong ; Lu, Mengjie ; Liu, Dongsheng ; Yang, Lingyun ; Yi, Cuiying ; Ma, Limin ; Zhang, Hui ; Liu, Qing ; Frimurer, Thomas M. ; Wang, Ming-Wei ; Schwartz, Thue W. ; Stevens, Raymond C. ; Wu, Beili ; Wüthrich, Kurt ; Zhao, Qiang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-02, Vol.10 (1), p.638-638, Article 638
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The SP/NK1R system promotes the proliferation of breast cancer cells through NF-κB-mediated inflammatory responses
Author / Creator:Jafarinezhad, Samine ; Assaran Darban, Reza ; Javid, Hossein ; Hashemy, Seyed Isaac
Publisher:New York: Springer US
Journal title:Cell biochemistry and biophysics, 2023-12, Vol.81 (4), p.787-794
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Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists
Author / Creator:Schöppe, Jendrik ; Ehrenmann, Janosch ; Klenk, Christoph ; Rucktooa, Prakash ; Schütz, Marco ; Doré, Andrew S. ; Plückthun, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.17-11, Article 17
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Dexamethasone-sparing on days 2–4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)
Author / Creator:Minatogawa, Hiroko ; Izawa, Naoki ; Shimomura, Kazuhiro ; Arioka, Hitoshi ; Iihara, Hirotoshi ; Sugawara, Mitsuhiro ; Morita, Hajime ; Mochizuki, Ayako ; Nawata, Shuichi ; Mishima, Keisuke ; Tsuboya, Ayako ; Miyaji, Tempei ; Honda, Kazunori ; Yokomizo, Ayako ; Hashimoto, Naoya ; Yanagihara, Takeshi ; Endo, Junki ; Kawaguchi, Takashi ; Furuya, Naoki ; Sone, Yumiko ; Inada, Yusuke ; Ohno, Yasushi ; Katada, Chikatoshi ; Hida, Naoya ; Akiyama, Kana ; Ichikura, Daisuke ; Konomatsu, Akiko ; Ogura, Takashi ; Yamaguchi, Takuhiro ; Nakajima, Takako Eguchi
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2024-02, Vol.130 (2), p.224-232
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A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ
Author / Creator:Lim, Ji Eun ; Chung, Eunkyung ; Son, Youngsook
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.9417-19, Article 9417
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Vesicle protrusion induced by antimicrobial peptides suggests common carpet mechanism for short antimicrobial peptides
Author / Creator:Park, Peter ; Matsubara, Danilo K. ; Barzotto, Domenico R. ; Lima, Filipe S. ; Chaimovich, Hernan ; Marrink, Siewert J. ; Cuccovia, Iolanda M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-04, Vol.14 (1), p.9701-9701, Article 9701
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Characterisation of lamina I anterolateral system neurons that express Cre in a Phox2a-Cre mouse line
Author / Creator:Alsulaiman, Wafa A. A. ; Quillet, Raphaelle ; Bell, Andrew M. ; Dickie, Allen C. ; Polgár, Erika ; Boyle, Kieran A. ; Watanabe, Masahiko ; Roome, R. Brian ; Kania, Artur ; Todd, Andrew J. ; Gutierrez-Mecinas, Maria
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-09, Vol.11 (1), p.17912-17912, Article 17912
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A quantitative study of inhibitory interneurons in laminae I-III of the mouse spinal dorsal horn
Author / Creator:Polgár, Erika ; Durrieux, Camille ; Hughes, David I ; Todd, Andrew J
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e78309-e78309
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Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord
Author / Creator:Bardoni, Rita ; Shen, Kai-Feng ; Li, Hui ; Jeffry, Joseph ; Barry, Devin M. ; Comitato, Antonella ; Li, Yun-Qing ; Chen, Zhou-Feng
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-11, Vol.9 (1), p.15804-11, Article 15804
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Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Author / Creator:Chiu, Joanne Wing Yan ; Lee, Soo Chin ; Ho, James Chung-man ; Park, Yeon Hee ; Chao, Ta-Chung ; Kim, Sung-Bae ; Lim, Elgene ; Lin, Ching-Hung ; Loi, Sherene ; Low, Su Ying ; Teo, Lynette Li San ; Yeo, Winnie ; Dent, Rebecca
Publisher:Cham: Springer International Publishing
Journal title:Drug safety, 2023-10, Vol.46 (10), p.927-949
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Showing 1 to 20 of 252 results

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Prophylaxe von Übelkeit und Erbrechen nach medikamentöser Tumortherapie

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Substance P and pain chronicity

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Selective G protein signaling driven by substance P–neurokinin receptor dynamics

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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

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Clinical presentation, management, and pathophysiology of neuropathic itch

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SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors

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Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials

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The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury

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C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation

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Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload

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Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography

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The SP/NK1R system promotes the proliferation of breast cancer cells through NF-κB-mediated inflammatory responses

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Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists

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Dexamethasone-sparing on days 2–4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)

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A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ

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Vesicle protrusion induced by antimicrobial peptides suggests common carpet mechanism for short antimicrobial peptides

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Characterisation of lamina I anterolateral system neurons that express Cre in a Phox2a-Cre mouse line

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A quantitative study of inhibitory interneurons in laminae I-III of the mouse spinal dorsal horn

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Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord

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Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel

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