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ArticlesPeer ReviewedFull Text
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
Author / Creator:Chakraborty, Abhishek A. ; Laukka, Tuomas ; Myllykoski, Matti ; Ringel, Alison E. ; Booker, Matthew A. ; Tolstorukov, Michael Y. ; Meng, Yuzhong Jeff ; Meier, Samuel R. ; Jennings, Rebecca B. ; Creech, Amanda L. ; Herbert, Zachary T. ; McBrayer, Samuel K. ; Olenchock, Benjamin A. ; Jaffe, Jacob D. ; Haigis, Marcia C. ; Beroukhim, Rameen ; Signoretti, Sabina ; Koivunen, Peppi ; Kaelin, William G.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6432), p.1217-1222
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Sulfide catabolism ameliorates hypoxic brain injury
Author / Creator:Marutani, Eizo ; Morita, Masanobu ; Hirai, Shuichi ; Kai, Shinichi ; Grange, Robert M. H. ; Miyazaki, Yusuke ; Nagashima, Fumiaki ; Traeger, Lisa ; Magliocca, Aurora ; Ida, Tomoaki ; Matsunaga, Tetsuro ; Flicker, Daniel R. ; Corman, Benjamin ; Mori, Naohiro ; Yamazaki, Yumiko ; Batten, Annabelle ; Li, Rebecca ; Tanaka, Tomohiro ; Ikeda, Takamitsu ; Nakagawa, Akito ; Atochin, Dmitriy N. ; Ihara, Hideshi ; Olenchock, Benjamin A. ; Shen, Xinggui ; Nishida, Motohiro ; Hanaoka, Kenjiro ; Kevil, Christopher G. ; Xian, Ming ; Bloch, Donald B. ; Akaike, Takaaki ; Hindle, Allyson G. ; Motohashi, Hozumi ; Ichinose, Fumito
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.3108-19, Article 3108
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ArticlesPeer ReviewedFull Text
MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia
Author / Creator:Copeland, Courtney A ; Olenchock, Benjamin A ; Ziehr, David ; McGarrity, Sarah ; Leahy, Kevin ; Young, Jamey D ; Loscalzo, Joseph ; Oldham, William M
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2023-07, Vol.12
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Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first‐in‐human phase I study
Author / Creator:Gewitz, Andrew ; Mendell, Jeanne ; Wang, Yuhuan ; Harris, Charles ; Olenchock, Benjamin A. ; Podgrabinska, Simona ; Zheng, Wenjun ; Zhao, An ; Pan, Hao ; Vanhoutte, Frédéric ; Davis, John D.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2024-04, Vol.17 (4), p.e13762-n/a
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Fulminant Myocarditis with Combination Immune Checkpoint Blockade
Author / Creator:Johnson, Douglas B ; Balko, Justin M ; Compton, Margaret L ; Chalkias, Spyridon ; Gorham, Joshua ; Xu, Yaomin ; Hicks, Mellissa ; Puzanov, Igor ; Alexander, Matthew R ; Bloomer, Tyler L ; Becker, Jason R ; Slosky, David A ; Phillips, Elizabeth J ; Pilkinton, Mark A ; Craig-Owens, Laura ; Kola, Nina ; Plautz, Gregory ; Reshef, Daniel S ; Deutsch, Jonathan S ; Deering, Raquel P ; Olenchock, Benjamin A ; Lichtman, Andrew H ; Roden, Dan M ; Seidman, Christine E ; Koralnik, Igor J ; Seidman, Jonathan G ; Hoffman, Robert D ; Taube, Janis M ; Diaz, Luis A ; Anders, Robert A ; Sosman, Jeffrey A ; Moslehi, Javid J
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2016-11, Vol.375 (18), p.1749-1755
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ArticlesPeer ReviewedFull Text
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells
Author / Creator:Fendt, Sarah-Maria ; Bell, Eric L. ; Keibler, Mark A. ; Olenchock, Benjamin A. ; Mayers, Jared R. ; Wasylenko, Thomas M. ; Vokes, Natalie I. ; Guarente, Leonard ; Heiden, Matthew G. Vander ; Stephanopoulos, Gregory
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013, Vol.4 (1), p.2236-2236, Article 2236
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ArticlesPeer ReviewedFull Text
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus
Author / Creator:Russo, Louise A ; Peano, Bryan J ; Trivedi, Shreya P ; Cavalcanto, Todd D ; Olenchock, Benjamin A ; Caruso, Joseph A ; Smolock, Amanda R ; Vishnevsky, Oleg ; Gardner, Russell M
Publisher:England: BioMed Central Ltd
Journal title:Reproductive biology and endocrinology, 2009-11, Vol.7 (1), p.124-124, Article 124
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ArticlesPeer ReviewedFull Text
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
Author / Creator:Olenchock, Benjamin A ; Guo, Rishu ; Carpenter, Jeffery H ; Jordan, Martha ; Topham, Matthew K ; Koretzky, Gary A ; Zhong, Xiao-Ping
Publisher:New York: Nature Publishing Group US
Journal title:Nature Immunology, 2006-11, Vol.7 (11), p.1174-1181
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Effect of timing of casirivimab and imdevimab administration relative to mRNA-1273 COVID-19 vaccination on vaccine-induced SARS-CoV-2 neutralising antibody responses: a prospective, open-label, phase...
Author / Creator:Isa, Flonza ; Gonzalez Ortiz, Ana M ; Meyer, Jonathan ; Hamilton, Jennifer D ; Olenchock, Benjamin A ; Brackin, Taylor ; Ganguly, Samit ; Forleo-Neto, Eduardo ; Faria, Lori ; Heirman, Ingeborg ; Marovich, Mary ; Hutter, Julia ; Polakowski, Laura ; Irvin, Susan C ; Thakur, Mazhar ; Hooper, Andrea T ; Baum, Alina ; Petro, Christopher D ; Fakih, Faisal A ; McElrath, M Juliana ; De Rosa, Stephen C ; Cohen, Kristen W ; Williams, LaTonya D ; Hellman, Caleb A ; Odeh, Ahmad J ; Patel, Aloki H ; Tomaras, Georgia D ; Geba, Gregory P ; Kyratsous, Christos A ; Musser, Bret ; Yancopoulos, George D ; Herman, Gary A ; Turner, Kenneth C ; Kim, Yunji ; Konis, George ; Rosenthal, Mark J ; Trbovic, Caryn F ; Kowal, Bari ; DiCioccio, A Thomas ; Dakin, Paula
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2025-01, Vol.25 (1), p.52-67
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ArticlesPeer ReviewedFull Text
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
Author / Creator:McBrayer, Samuel K. ; Olenchock, Benjamin A. ; DiNatale, Gabriel J. ; Shi, Diana D. ; Khanal, Januka ; Jennings, Rebecca B. ; Novak, Jesse S. ; Oser, Matthew G. ; Robbins, Alissa K. ; Modiste, Rebecca ; Bonal, Dennis ; Moslehi, Javid ; Bronson, Roderick T. ; Neuberg, Donna ; Nguyen, Quang-De ; Signoretti, Sabina ; Losman, Julie-Aurore ; Kaelin, William G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (16), p.E3741-E3748
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ArticlesPeer ReviewedFull Text
Enhanced T cell responses due to diacylglycerol kinase ζ deficiency
Author / Creator:Zhong, Xiao-Ping ; Hainey, Ehmonie A ; Olenchock, Benjamin A ; Jordan, Martha S ; Maltzman, Jonathan S ; Nichols, Kim E ; Shen, Hao ; Koretzky, Gary A
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2003-09, Vol.4 (9), p.882-890
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ArticlesPeer ReviewedFull Text
Lack of association between soluble CD40L and risk in a large cohort of patients with acute coronary syndrome in OPUS TIMI-16
Author / Creator:Olenchock, Benjamin A. ; Wiviott, Stephen D. ; Murphy, Sabina A. ; Cannon, Christopher P. ; Rifai, Nader ; Braunwald, Eugene ; Morrow, David A.
Publisher:Boston: Springer US
Journal title:Journal of thrombosis and thrombolysis, 2008-10, Vol.26 (2), p.79-84
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Regulation of Hematopoietic Cell Development and Activation by Adapter Proteins
Author / Creator:Koretzky, Gary A. ; Abtahian, Farhad ; Derimanov, Geo S. ; Dmowski, Sally A. ; Guerriero, Anastasia ; Jordan, Martha S. ; Maltzman, Jonathan S. ; Olenchock, Benjamin A. ; Singer, Andrew L.
Publisher:United States: Springer Nature B.V
Journal title:Immunologic research, 2003-01, Vol.27 (2-3), p.357-366
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ArticlesPeer ReviewedFull Text
Reductive glutamine metabolism is a function of the [alpha]-ketoglutarate to citrate ratio in cells
Author / Creator:Fendt, Sarah-maria ; Bell, Eric L ; Keibler, Mark A ; Olenchock, Benjamin A ; Mayers, Jared R ; Wasylenko, Thomas M ; Vokes, Natalie I ; Guarente, Leonard ; Heiden, Matthew G Vander ; Stephanopoulos, Gregory
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2013-07, Vol.4, p.2236
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Enhanced T cell responses due to diacylglycerol kinase [zeta] deficiency
Author / Creator:Xiao-Ping, Zhong ; Hainey, Ehmonie A ; Olenchock, Benjamin A ; Jordan, Martha S ; Maltzman, Jonathan S ; Nichols, Kim E ; Shen, Hao ; Koretzky, Gary A
Publisher:New York: Nature Publishing Group
Journal title:Nature immunology, 2003-09, Vol.4 (9), p.882
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Enhanced T cell responses due to diacylglycerol kinase θ deficiency
Author / Creator:Zhong, Xiao-Ping ; Hainey, Ehmonie A ; Olenchock, Benjamin A ; Jordan, Martha S ; Maltzman, Jonathan S ; Nichols, Kim E ; Shen, Hao ; Koretzky, Gary A
Publisher:Nature Publishing Group
Journal title:Nature immunology, 2003-09, Vol.4 (9), p.882
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ArticlesFull Text
MYC uncouples HIF target gene expression from glycolytic flux in hypoxic proliferating primary cells
Author / Creator:Copeland, Courtney A ; Olenchock, Benjamin A ; Ziehr, David ; Mcgarrity, Sarah ; Leahy, Kevin ; Young, Jamey D ; Loscalzo, Joseph ; Oldham, William M
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-12
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ArticlesPeer ReviewedFull Text
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
Author / Creator:Ridker, Paul M ; Everett, Brendan M ; Thuren, Tom ; MacFadyen, Jean G ; Chang, William H ; Ballantyne, Christie ; Fonseca, Francisco ; Nicolau, Jose ; Koenig, Wolfgang ; Anker, Stefan D ; Kastelein, John J.P ; Cornel, Jan H ; Pais, Prem ; Pella, Daniel ; Genest, Jacques ; Cifkova, Renata ; Lorenzatti, Alberto ; Forster, Tamas ; Kobalava, Zhanna ; Vida-Simiti, Luminita ; Flather, Marcus ; Shimokawa, Hiroaki ; Ogawa, Hisao ; Dellborg, Mikael ; Rossi, Paulo R.F ; Troquay, Roland P.T ; Libby, Peter ; Glynn, Robert J
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-09, Vol.377 (12), p.1119-1131
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ArticlesPeer ReviewedFull Text
Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial
Author / Creator:Ridker, Paul M ; MacFadyen, Jean G ; Thuren, Tom ; Everett, Brendan M ; Libby, Peter ; Glynn, Robert J ; Ridker, Paul ; Lorenzatti, Alberto ; Krum, Henry ; Varigos, John ; Siostrzonek, Peter ; Sinnaeve, Peter ; Fonseca, Francisco ; Nicolau, Jose ; Gotcheva, Nina ; Genest, Jacques ; Yong, Huo ; Urina-Triana, Miguel ; Milicic, Davor ; Cifkova, Renata ; Vettus, Riina ; Koenig, Wolfgang ; Anker, Stephan D ; Manolis, Athanasios J ; Wyss, Fernando ; Forster, Tamas ; Sigurdsson, Axel ; Pais, Prem ; Ogawa, Hisao ; Shimokawa, Hiroaki ; Veze, Irina ; Petrauskiene, Birute ; Salvador, Leon ; Kastelein, John ; Cornel, Jan Hein ; Medina, Felix ; Budaj, Andrzej ; Vida-Simiti, Luminita ; Kobalava, Zhanna ; Otasevic, Petar ; Pella, Daniel ; Lainscak, Mitja ; Seung, Ki-Bae ; Dellborg, Mikael ; Donath, Marc ; Hwang, Juey-Jen ; Kultursay, Hakan ; Flather, Marcus ; Ballantyne, Christie ; Bilazarian, Seth ; East, Cara ; Everett, Brendan ; Forgosh, Les ; Glynn, Robert ; Harris, Barry ; Libby, Peter ; Ligueros, Monica ; Thuren, Tom ; Bohula, Erin ; Charmarthi, Bindu ; Cheng, Susan ; Chou, Sherry ; Danik, Jacqueline ; Olenchock, Benjamin ; Pande, Reena ; Perlstein, Todd ; Pradhan, Aruna ; Rost, Natalia ; Singhal, Aneesh ; Taqueti, Viviany ; Wei, Nancy ; Burris, Howard ; Cioffi, Angela ; Dalseg, Anne Marie ; Ghosh, Nilanjan ; Gralow, Julie ; Rugo, Hope ; Limaye, Ajit P ; Cosgrove, Sara ; Lopes, Renato ; Scott, John ; Hilkert, Robert ; Tamesby, Georgia ; Manning, Brian ; Woelcke, Julian ; Manfreda, Sheryl ; Ponce, Tom ; Kam, Jane ; Saini, Ravinder ; Banker, Kehur ; Tawfik, Ronda ; Manne, Shobha ; Jirvankar, Pravin ; Lal, Shankar ; Jose, Jaison ; Collins, Rory ; Bailey, Kent ; Blumenthal, Roger ; Colhoun, Helen ; Gersh, Bernard
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-10, Vol.390 (10105), p.1833-1842
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ArticlesFull Text
The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate
Author / Creator:Chakraborty, Abhishek ; Laukka, Tuomas ; Myllykoski, Matti ; Ringel, Alison ; Booker, Matthew ; Tolstorukov, Michael ; Meng, Yuzhong ; Meier, Sam ; Jennings, Rebecca ; Creech, Amanda ; Zachary, Herbert ; Spinelli, Jessica ; Mcbrayer, Samuel ; Olenchock, Benjamin ; Jaffe, Jacob ; Haigis, Marcia ; Beroukhim, Rameen ; Signoretti, Sabina ; Koivunen, Peppi ; Kaelin, William G
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-01
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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate

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Sulfide catabolism ameliorates hypoxic brain injury

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MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia

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Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first‐in‐human phase I study

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Fulminant Myocarditis with Combination Immune Checkpoint Blockade

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Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells

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Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus

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Disruption of diacylglycerol metabolism impairs the induction of T cell anergy

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Effect of timing of casirivimab and imdevimab administration relative to mRNA-1273 COVID-19 vaccination on vaccine-induced SARS-CoV-2 neutralising antibody responses: a prospective, open-label, phase...

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Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase

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Enhanced T cell responses due to diacylglycerol kinase ζ deficiency

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Lack of association between soluble CD40L and risk in a large cohort of patients with acute coronary syndrome in OPUS TIMI-16

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Regulation of Hematopoietic Cell Development and Activation by Adapter Proteins

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Reductive glutamine metabolism is a function of the [alpha]-ketoglutarate to citrate ratio in cells

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Enhanced T cell responses due to diacylglycerol kinase [zeta] deficiency

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Enhanced T cell responses due to diacylglycerol kinase θ deficiency

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MYC uncouples HIF target gene expression from glycolytic flux in hypoxic proliferating primary cells

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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

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Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

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The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

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