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p300/CBP and cancer
Author / Creator:Iyer, Narayanan Gopalakrishna ; Özdag, Hilal ; Caldas, Carlos
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2004-05, Vol.23 (24), p.4225-4231
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Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Author / Creator:Lasko, Loren M. ; Jakob, Clarissa G. ; Edalji, Rohinton P. ; Qiu, Wei ; Montgomery, Debra ; Digiammarino, Enrico L. ; Hansen, T. Matt ; Risi, Roberto M. ; Frey, Robin ; Manaves, Vlasios ; Shaw, Bailin ; Algire, Mikkel ; Hessler, Paul ; Lam, Lloyd T. ; Uziel, Tamar ; Faivre, Emily ; Ferguson, Debra ; Buchanan, Fritz G. ; Martin, Ruth L. ; Torrent, Maricel ; Chiang, Gary G. ; Karukurichi, Kannan ; Langston, J. William ; Weinert, Brian T. ; Choudhary, Chunaram ; de Vries, Peter ; Kluge, Arthur F. ; Patane, Michael A. ; Van Drie, John H. ; Wang, Ce ; McElligott, David ; Kesicki, Ed ; Marmorstein, Ronen ; Sun, Chaohong ; Cole, Philip A. ; Rosenberg, Saul H. ; Michaelides, Michael R. ; Lai, Albert ; Bromberg, Kenneth D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-10, Vol.550 (7674), p.128-132
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p300/CBP keeps chromatin silent
Author / Creator:Wrighton, Katharine H.
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2022-11, Vol.29 (11), p.1039-1039
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Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation
Author / Creator:Zhou, Yixuan ; Bastian, Ingmar Niels ; Long, Mark D. ; Dow, Michelle ; Li, Weihua ; Liu, Tao ; Ngu, Rachael Katie ; Antonucci, Laura ; Huang, Jian Yu ; Phung, Qui T. ; Zhao, Xi-he ; Banerjee, Sourav ; Lin, Xue-Jia ; Wang, Hongxia ; Dang, Brian ; Choi, Sylvia ; Karin, Daniel ; Su, Hua ; Ellisman, Mark H. ; Jamieson, Christina ; Bosenberg, Marcus ; Cheng, Zhang ; Haybaeck, Johannes ; Kenner, Lukas ; Fisch, Kathleen M. ; Bourgon, Richard ; Hernandez, Genevive ; Lill, Jennie R. ; Liu, Song ; Carter, Hannah ; Mellman, Ira ; Karin, Michael ; Shalapour, Shabnam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (8), p.1-12
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Epigenetic mechanisms to propagate histone acetylation by p300/CBP
Author / Creator:Kikuchi, Masaki ; Morita, Satoshi ; Wakamori, Masatoshi ; Sato, Shin ; Uchikubo-Kamo, Tomomi ; Suzuki, Takehiro ; Dohmae, Naoshi ; Shirouzu, Mikako ; Umehara, Takashi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-07, Vol.14 (1), p.4103-4103, Article 4103
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p300/CBP inhibition enhances the efficacy of programmed death-ligand 1 blockade treatment in prostate cancer
Author / Creator:Liu, Jinghui ; He, Daheng ; Cheng, Lijun ; Huang, Changkun ; Zhang, Yanquan ; Rao, Xiongjian ; Kong, Yifan ; Li, Chaohao ; Zhang, Zhuangzhuang ; Liu, Jinpeng ; Jones, Karrie ; Napier, Dana ; Lee, Eun Y. ; Wang, Chi ; Liu, Xiaoqi
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-05, Vol.39 (19), p.3939-3951
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Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy
Author / Creator:Chen, Xu ; Li, Yaqiao ; Wang, Chao ; Tang, Yinyan ; Mok, Sue-Ann ; Tsai, Richard M. ; Rojas, Julio C. ; Karydas, Anna ; Miller, Bruce L. ; Boxer, Adam L. ; Gestwicki, Jason E. ; Arkin, Michelle ; Cuervo, Ana Maria ; Gan, Li
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2020-01, Vol.15 (1), p.2-2, Article 2
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EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore–microtubule interactions in mitosis
Author / Creator:Xia, Peng ; Wang, Zhikai ; Liu, Xing ; Wu, Bing ; Wang, Juncheng ; Ward, Tarsha ; Zhang, Liangyu ; Ding, Xia ; Gibbons, Gary ; Shi, Yunyu ; Yao, Xuebiao
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.16564-16569
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P300/CBP-Associated Factor Activates Cardiac Fibroblasts by SMAD2 Acetylation
Author / Creator:Lim, Yongwoon ; Jeong, Anna ; Kwon, Duk-Hwa ; Lee, Yeong-Un ; Kim, Young-Kook ; Ahn, Youngkeun ; Kook, Taewon ; Park, Woo-Jin ; Kook, Hyun
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-09, Vol.22 (18), p.9944
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Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma
Author / Creator:Zhang, Xin ; Zegar, Tim ; Lucas, Anais ; Morrison-Smith, Chevaun ; Knox, Tatiana ; French, Christopher A. ; Knapp, Stefan ; Müller, Susanne ; Siveke, Jens T.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-06, Vol.39 (24), p.4770-4779
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E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair
Author / Creator:Manickavinayaham, Swarnalatha ; Vélez-Cruz, Renier ; Biswas, Anup K. ; Bedford, Ella ; Klein, Brianna J. ; Kutateladze, Tatiana G. ; Liu, Bin ; Bedford, Mark T. ; Johnson, David G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-10, Vol.10 (1), p.4951-14, Article 4951
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Induction of NKG2D ligand expression on tumor cells by CD8+ T-cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor
Author / Creator:Hu, Jiemiao ; Xia, Xueqing ; Gorlick, Richard ; Li, Shulin
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2019-12, Vol.38 (49), p.7433-7446
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Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
Author / Creator:Sen, Nilkantha ; Hara, Makoto R. ; Kornberg, Michael D. ; Cascio, Matthew B. ; Bae, Byoung-Il ; Shahani, Neelam ; Thomas, Bobby ; Dawson, Ted M. ; Dawson, Valina L. ; Snyder, Solomon H. ; Sawa, Akira
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2008-07, Vol.10 (7), p.866-873
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Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma
Author / Creator:Wei, Erdong ; Mitanoska, Ana ; O’Brien, Quinn ; Porter, Kendall ; Molina, MacKenzie ; Ahsan, Haseeb ; Jung, Usuk ; Mills, Lauren ; Kyba, Michael ; Bosnakovski, Darko
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2024-10, Vol.23 (1), p.222-22, Article 222
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The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
Author / Creator:Liu, Xin ; Wang, Ling ; Zhao, Kehao ; Thompson, Paul R. ; Hwang, Yousang ; Marmorstein, Ronen ; Cole, Philip A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2008-02, Vol.451 (7180), p.846-850
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Inhibition of p300/CBP-Associated Factor Attenuates Renal Tubulointerstitial Fibrosis through Modulation of NF-kB and Nrf2
Author / Creator:Chung, Sungjin ; Kim, Soojeong ; Son, Mina ; Kim, Minyoung ; Koh, Eun Sil ; Shin, Seok Joon ; Park, Cheol Whee ; Kim, Ho-Shik
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-03, Vol.20 (7), p.1554
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p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization
Author / Creator:Peng, Jinjin ; Li, Jiacheng ; Huang, Jing ; Xu, Pan ; Huang, Heming ; Liu, Yanjun ; Yu, Liang ; Yang, Yaxi ; Zhou, Bing ; Jiang, Hualiang ; Chen, Kaixian ; Dang, Yongjun ; Zhang, Yuanyuan ; Luo, Cheng ; Li, Guangming
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2019-01, Vol.9 (26), p.8344-8361
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Garcinol promotes hepatic gluconeogenesis by inhibiting P300/CBP-associated factor in late-pregnant sows
Author / Creator:Yao, Weilei ; Xia, Jun ; Wang, Tongxin ; Li, Juan ; Huang, Lu ; Huang, Feiruo
Publisher:Cambridge, UK: Cambridge University Press
Journal title:British journal of nutrition, 2021-07, Vol.126 (1), p.1-8
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P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer
Author / Creator:Cheng, Yin‐Wei ; Zeng, Fa‐Min ; Li, Da‐Jia ; Wang, Shao‐Hong ; He, Jian‐Zhong ; Guo, Zhen‐Chang ; Nie, Ping‐Juan ; Wu, Zhi‐Yong ; Shi, Wen‐Qi ; Wen, Bing ; Xu, Xiu‐E ; Liao, Lian‐Di ; Li, Zhi‐Mao ; Wu, Jian‐Yi ; Zhan, Jun ; Zhang, Hong‐Quan ; Chang, Zhi‐Jie ; Zhang, Kai ; Xu, Li‐Yan ; Li, En‐Min
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer communications (London, England), 2021-12, Vol.41 (12), p.1398-1416
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Downregulation of p300/CBP‐associated factor inhibits cardiomyocyte apoptosis via suppression of NF‐κB pathway in ischaemia/reperfusion injury rats
Author / Creator:Qiu, Liqiang ; Liu, Xiaoxiong ; Li, Wenjing ; Liu, Zhebo ; Xu, Changwu ; Xia, Hao
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2021-11, Vol.25 (21), p.10224-10235
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p300/CBP and cancer

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Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

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p300/CBP keeps chromatin silent

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Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation

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Epigenetic mechanisms to propagate histone acetylation by p300/CBP

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p300/CBP inhibition enhances the efficacy of programmed death-ligand 1 blockade treatment in prostate cancer

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Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

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EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore–microtubule interactions in mitosis

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P300/CBP-Associated Factor Activates Cardiac Fibroblasts by SMAD2 Acetylation

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Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma

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E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair

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Induction of NKG2D ligand expression on tumor cells by CD8+ T-cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor

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Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

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Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma

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The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

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Inhibition of p300/CBP-Associated Factor Attenuates Renal Tubulointerstitial Fibrosis through Modulation of NF-kB and Nrf2

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p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization

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Garcinol promotes hepatic gluconeogenesis by inhibiting P300/CBP-associated factor in late-pregnant sows

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P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer

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Downregulation of p300/CBP‐associated factor inhibits cardiomyocyte apoptosis via suppression of NF‐κB pathway in ischaemia/reperfusion injury rats

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