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Evolving synergistic combinations of targeted immunotherapies to combat cancer
Author / Creator:Melero, Ignacio ; Berman, David M. ; Aznar, M. Angela ; Korman, Alan J. ; Gracia, José Luis Pérez ; Haanen, John
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2015-08, Vol.15 (8), p.457-472
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Dual modulation of MCL-1 and mTOR determines the response to sunitinib
Author / Creator:Elgendy, Mohamed ; Abdel-Aziz, Amal Kamal ; Renne, Salvatore Lorenzo ; Bornaghi, Viviana ; Procopio, Giuseppe ; Colecchia, Maurizio ; Kanesvaran, Ravindran ; Toh, Chee Keong ; Bossi, Daniela ; Pallavicini, Isabella ; Perez-Gracia, Jose Luis ; Lozano, Maria Dolores ; Giandomenico, Valeria ; Mercurio, Ciro ; Lanfrancone, Luisa ; Fazio, Nicola ; Nole, Franco ; Teh, Bin Tean ; Renne, Giuseppe ; Minucci, Saverio
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017, Vol.127 (1), p.153-168
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Cellular cytotoxicity is a form of immunogenic cell death
Author / Creator:Minute, Luna ; Teijeira, Alvaro ; Sanchez-Paulete, Alfonso R ; Ochoa, Maria C ; Alvarez, Maite ; Otano, Itziar ; Etxeberrria, Iñaki ; Bolaños, Elixabet ; Azpilikueta, Arantza ; Garasa, Saray ; Casares, Noelia ; Luis Perez Gracia, Jose ; Rodriguez-Ruiz, Maria E ; Berraondo, Pedro ; Melero, Ignacio
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-03, Vol.8 (1), p.e000325
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A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis
Author / Creator:Rodriguez, Javier ; Castañón, Eduardo ; Perez-Gracia, Jose Luis ; Rodriguez, Inmaculada ; Viudez, Antonio ; Alfaro, Carlos ; Oñate, Carmen ; Perez, Guiomar ; Rotellar, Fernando ; Inogés, Susana ; López-Diaz de Cerio, Ascensión ; Resano, Leyre ; Ponz-Sarvise, Mariano ; Rodriguez-Ruiz, Maria E ; Chopitea, Ana ; Vera, Ruth ; Melero, Ignacio
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2018-09, Vol.6 (1), p.96-96, Article 96
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Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies
Author / Creator:Glez-Vaz, Javier ; Azpilikueta, Arantza ; Olivera, Irene ; Cirella, Assunta ; Teijeira, Alvaro ; Ochoa, Maria C ; Alvarez, Maite ; Eguren-Santamaria, Iñaki ; Luri-Rey, Carlos ; Rodriguez-Ruiz, Maria E ; Nie, Xinxin ; Chen, Lieping ; Guedan, Sonia ; Sanmamed, Miguel F ; Luis Perez Gracia, Jose ; Melero, Ignacio
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-03, Vol.10 (3), p.e003532
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Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy
Author / Creator:Perez-Ruiz, Elisabeth ; Minute, Luna ; Otano, Itziar ; Alvarez, Maite ; Ochoa, Maria Carmen ; Belsue, Virginia ; de Andrea, Carlos ; Rodriguez-Ruiz, Maria Esperanza ; Perez-Gracia, Jose Luis ; Marquez-Rodas, Ivan ; Llacer, Casilda ; Alvarez, Martina ; de Luque, Vanesa ; Molina, Carmen ; Teijeira, Alvaro ; Berraondo, Pedro ; Melero, Ignacio
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-05, Vol.569 (7756), p.428-432
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Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors
Author / Creator:Schalper, Kurt A. ; Carleton, Michael ; Zhou, Ming ; Chen, Tian ; Feng, Ye ; Huang, Shu-Pang ; Walsh, Alice M. ; Baxi, Vipul ; Pandya, Dimple ; Baradet, Timothy ; Locke, Darren ; Wu, Qiuyan ; Reilly, Timothy P. ; Phillips, Penny ; Nagineni, Venkata ; Gianino, Nicole ; Gu, Jianlei ; Zhao, Hongyu ; Perez-Gracia, Jose Luis ; Sanmamed, Miguel F. ; Melero, Ignacio
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-05, Vol.26 (5), p.688-692
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Carcinoma-derived interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
Author / Creator:Alfaro, Carlos ; Suárez, Natalia ; Martínez-Forero, Ivan ; Palazón, Asís ; Rouzaut, Ana ; Solano, Sarai ; Feijoo, Esperanza ; Gúrpide, Alfonso ; Bolaños, Elixabet ; Erro, Lorena ; Dubrot, Juan ; Hervás-Stubbs, Sandra ; Gonzalez, Alvaro ; Perez-Gracia, Jose Luis ; Melero, Ignacio
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-03, Vol.6 (3), p.e17922-e17922
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Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco‐induced lung cancer
Author / Creator:Fusco, Juan Pablo ; Pita, Guillermo ; Pajares, María José ; Andueza, Maria Pilar ; Patiño‐García, Ana ; de‐Torres, Juan P. ; Gurpide, Alfonso ; Zulueta, Javier ; Alonso, Rosario ; Alvarez, Nuria ; Pio, Ruben ; Melero, Ignacio ; Sanmamed, Miguel F. ; Rodriguez Ruiz, Maria ; Gil‐Bazo, Ignacio ; Lopez‐Picazo, Jose María ; Casanova, Ciro ; Baz Davila, Rebeca ; Agudo, Antonio ; Lozano, Maria Dolores ; Gonzalez, Alvaro ; Sala, Nuria ; Ardanaz, Eva ; Benitez, Javier ; Montuenga, Luis ; Gonzalez‐Neira, Anna ; Perez‐Gracia, Jose Luis
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2018-07, Vol.7 (7), p.3474-3483
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Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial
Author / Creator:Balar, Arjun V, Dr ; Galsky, Matthew D, MD ; Rosenberg, Jonathan E, MD ; Powles, Thomas, MD ; Petrylak, Daniel P, MD ; Bellmunt, Joaquim, MD ; Loriot, Yohann, MD ; Necchi, Andrea, MD ; Hoffman-Censits, Jean, MD ; Perez-Gracia, Jose Luis, MD ; Dawson, Nancy A, MD ; van der Heijden, Michiel S, MD ; Dreicer, Robert, MD ; Srinivas, Sandy, MD ; Retz, Margitta M, MD ; Joseph, Richard W, MD ; Drakaki, Alexandra, MD ; Vaishampayan, Ulka N, MD ; Sridhar, Srikala S, MD ; Quinn, David I, MD ; Durán, Ignacio, MD ; Shaffer, David R, MD ; Eigl, Bernhard J, MD ; Grivas, Petros D, MD ; Yu, Evan Y, MD ; Li, Shi, PhD ; Kadel, Edward E, BS ; Boyd, Zachary, MSc ; Bourgon, Richard, PhD ; Hegde, Priti S, PhD ; Mariathasan, Sanjeev, PhD ; Thåström, AnnChristine, PhD ; Abidoye, Oyewale O, MD ; Fine, Gregg D, MD ; Bajorin, Dean F, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-01, Vol.389 (10064), p.67-76
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Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
Author / Creator:Rosenberg, Jonathan E, Dr ; Hoffman-Censits, Jean, MD ; Powles, Tom, Prof ; van der Heijden, Michiel S, Prof ; Balar, Arjun V, MD ; Necchi, Andrea, MD ; Dawson, Nancy, Prof ; O'Donnell, Peter H, MD ; Balmanoukian, Ani, MD ; Loriot, Yohann, MD ; Srinivas, Sandy, MD ; Retz, Margitta M, Prof ; Grivas, Petros, MD ; Joseph, Richard W, MD ; Galsky, Matthew D, MD ; Fleming, Mark T, MD ; Petrylak, Daniel P, Prof ; Perez-Gracia, Jose Luis, MD ; Burris, Howard A, MD ; Castellano, Daniel, MD ; Canil, Christina, MD ; Bellmunt, Joaquim, MD ; Bajorin, Dean, Prof ; Nickles, Dorothee, PhD ; Bourgon, Richard, PhD ; Frampton, Garrett M, PhD ; Cui, Na, PhD ; Mariathasan, Sanjeev, PhD ; Abidoye, Oyewale, MD ; Fine, Gregg D, MD ; Dreicer, Robert, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-05, Vol.387 (10031), p.1909-1920
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Pathological vertebral fracture after stereotactic body radiation therapy for lung metastases. Case report and literature review
Author / Creator:Rodríguez-Ruiz, María Esperanza ; San Miguel, Iñigo ; Gil-Bazo, Ignacio ; Perez-Gracia, Jose Luis ; Arbea, Leire ; Moreno-Jimenez, Marta ; Aristu, Javier
Publisher:England: BioMed Central Ltd
Journal title:Radiation oncology (London, England), 2012-03, Vol.7 (1), p.50-50, Article 50
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Anti-CSF-1R emactuzumab in combination with anti-PD-L1 atezolizumab in advanced solid tumor patients naïve or experienced for immune checkpoint blockade
Author / Creator:Gomez-Roca, Carlos ; Cassier, Philippe ; Zamarin, Dmitriy ; Machiels, Jean-Pascal ; Perez Gracia, Jose Luis ; Stephen Hodi, F ; Taus, Alvaro ; Martinez Garcia, Maria ; Boni, Valentina ; Eder, Joseph P ; Hafez, Navid ; Sullivan, Ryan ; Mcdermott, David ; Champiat, Stephane ; Aspeslagh, Sandrine ; Terret, Catherine ; Jegg, Anna-Maria ; Jacob, Wolfgang ; Cannarile, Michael A ; Ries, Carola ; Korski, Konstanty ; Michielin, Francesca ; Christen, Randolph ; Babitzki, Galina ; Watson, Carl ; Meneses-Lorente, Georgina ; Weisser, Martin ; Rüttinger, Dominik ; Delord, Jean-Pierre ; Marabelle, Aurelien
Publisher:England: BMJ Publishing Group
Journal title:Journal for immunotherapy of cancer, 2022-05, Vol.10 (5), p.e004076
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Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma
Author / Creator:Prior, Celia ; Perez-Gracia, Jose Luis ; Garcia-Donas, Jesus ; Rodriguez-Antona, Cristina ; Guruceaga, Elizabeth ; Esteban, Emilio ; Suarez, Cristina ; Castellano, Daniel ; del Alba, Aránzazu González ; Lozano, Maria Dolores ; Carles, Joan ; Climent, Miguel Angel ; Arranz, Jose Angel ; Gallardo, Enrique ; Puente, Javier ; Bellmunt, Joaquim ; Gurpide, Alfonso ; Lopez-Picazo, Jose Maria ; Hernandez, Alvaro Gonzalez ; Mellado, Begoña ; Martínez, Esther ; Moreno, Fernando ; Font, Albert ; Calvo, Alfonso
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e86263-e86263
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Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control
Author / Creator:Rodriguez-Ruiz, Maria E ; Serrano-Mendioroz, Irantzu ; Garate-Soraluze, Eneko ; Sánchez-Mateos, Paloma ; Barrio-Alonso, Celia ; Rodríguez López, Inmaculada ; Diaz Pascual, Victor ; Arbea Moreno, Leire ; Alvarez, Maite ; Sanmamed, Miguel F ; Perez-Gracia, Jose Luis ; Escuin-Ordinas, Helena ; Quintero, Marisol ; Melero, Ignacio
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-01, Vol.11 (1), p.e005011
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International Symposium: Trailblazing in Cancer Immunotherapy, October 29–31, 2017, Pamplona, Spain
Author / Creator:Berraondo, Pedro ; Aznar, Maria Angela ; Perez-Ruiz, Elisabeth ; Rodriguez-Ruiz, Maria Esperanza ; Castañon, Eduardo ; Perez-Gracia, Jose Luis ; Melero, Ignacio
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2018-11, Vol.67 (11), p.1809-1813
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Randomized pharmacokinetic study comparing subcutaneous and intravenous palonosetron in cancer patients treated with platinum based chemotherapy
Author / Creator:Sadaba, Belen ; del Barrio, Anabel ; Campanero, Miguel Angel ; Azanza, Jose Ramon ; Gomez-Guiu, Almudena ; Lopez-Picazo, Jose Maria ; Algarra, Salvador Martin ; Guillén Grimá, Francisco ; Blanco Prieto, Maria ; Perez-Gracia, Jose Luis ; Gurpide, Alfonso
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-02, Vol.9 (2), p.e89747
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Maintenance therapy with vinflunine plus best supportive care versus best supportive care alone in patients with advanced urothelial carcinoma with a response after first-line chemotherapy (MAJA; SOGU...
Author / Creator:García-Donas, Jesus, MD ; Font, Albert, MD ; Pérez-Valderrama, Begoña, MD ; Virizuela, José Antonio, MD ; Climent, Miquel Ángel, MD ; Hernando-Polo, Susana, MD ; Arranz, José Ángel, MD ; del Mar Llorente, Maria, MD ; Lainez, Nuria, MD ; Villa-Guzmán, José Carlos, MD ; Mellado, Begoña, MD ; del Alba, Aránzazu González, MD ; Castellano, Daniel, MD ; Gallardo, Enrique, MD ; Anido, Urbano, MD ; del Muro, Xavier García, MD ; Domènech, Montserrat, MD ; Puente, Javier, MD ; Morales-Barrera, Rafael, MD ; Pérez-Gracia, Jose Luis, MD ; Bellmunt, Joaquim, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-05, Vol.18 (5), p.672,681a-681,681a
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Efficacy and safety of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma: long-term follow-up of a phase 2 study
Author / Creator:Siefker-Radtke, Arlene O, Prof ; Necchi, Andrea, Prof ; Park, Se Hoon, MD ; García-Donas, Jesús, MD ; Huddart, Robert A, PhD ; Burgess, Earle F, MD ; Fleming, Mark T, MD ; Rezazadeh Kalebasty, Arash, MD ; Mellado, Begoña, MD ; Varlamov, Sergei, MD ; Joshi, Monika, MD ; Duran, Ignacio, MD ; Tagawa, Scott T, MD ; Zakharia, Yousef, MD ; Akapame, Sydney, PhD ; Santiago-Walker, Ademi E, PhD ; Monga, Manish, MD ; O'Hagan, Anne, MPH ; Loriot, Yohann, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2022-02, Vol.23 (2), p.248-258
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Association of [ 68 Ga]Ga-PSMA-11 PET/CT Metrics with PSA Persistence Following Radical Prostatectomy in Patients with Intermediate- and High-Risk Prostate Cancer
Author / Creator:Rosales, Juan J ; Betech-Antar, Vicky ; Mínguez, Fernando ; Guillén, Edgar F ; Prieto, Elena ; Quincoces, Gemma ; Beorlegui, Carmen ; Fenor de la Maza, María Dolores ; Díez-Caballero, Fernando ; Miñana, Bernardino ; Pérez-Gracia, José Luis ; Rodríguez-Fraile, Macarena
Publisher:Switzerland: MDPI AG
Journal title:Diagnostics (Basel), 2025-01, Vol.15 (3), p.301
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Showing 1 to 20 of 31 results

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Evolving synergistic combinations of targeted immunotherapies to combat cancer

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Dual modulation of MCL-1 and mTOR determines the response to sunitinib

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Cellular cytotoxicity is a form of immunogenic cell death

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A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis

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Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies

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Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

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Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors

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Carcinoma-derived interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation

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Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco‐induced lung cancer

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Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial

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Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

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Pathological vertebral fracture after stereotactic body radiation therapy for lung metastases. Case report and literature review

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Anti-CSF-1R emactuzumab in combination with anti-PD-L1 atezolizumab in advanced solid tumor patients naïve or experienced for immune checkpoint blockade

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Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma

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Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control

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International Symposium: Trailblazing in Cancer Immunotherapy, October 29–31, 2017, Pamplona, Spain

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Randomized pharmacokinetic study comparing subcutaneous and intravenous palonosetron in cancer patients treated with platinum based chemotherapy

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Maintenance therapy with vinflunine plus best supportive care versus best supportive care alone in patients with advanced urothelial carcinoma with a response after first-line chemotherapy (MAJA; SOGU...

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Efficacy and safety of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma: long-term follow-up of a phase 2 study

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Association of [ 68 Ga]Ga-PSMA-11 PET/CT Metrics with PSA Persistence Following Radical Prostatectomy in Patients with Intermediate- and High-Risk Prostate Cancer

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