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119 results for Piperidones+-+pharmacology

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ArticlesPeer ReviewedFull Text
Structural basis for the inhibition of the eukaryotic ribosome
Author / Creator:Garreau de Loubresse, Nicolas ; Prokhorova, Irina ; Holtkamp, Wolf ; Rodnina, Marina V. ; Yusupova, Gulnara ; Yusupov, Marat
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-09, Vol.513 (7519), p.517-522
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Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution
Author / Creator:Lee, Sooncheol ; Liu, Botao ; Lee, Soohyun ; Huang, Sheng-Xiong ; Shen, Ben ; Qian, Shu-Bing
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (37), p.E2424-E2432
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Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus
Author / Creator:Merrill, Joan T ; Werth, Victoria P ; Furie, Richard ; van Vollenhoven, Ronald ; Dörner, Thomas ; Petronijevic, Milan ; Velasco, Jorge ; Majdan, Maria ; Irazoque-Palazuelos, Fedra ; Weiswasser, Michael ; Korish, Shimon ; Ye, Ying ; Gaudy, Allison ; Schafer, Peter H ; Liu, Zhaohui ; Agafonova, Nataliya ; Delev, Nikolay
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-03, Vol.386 (11), p.1034-1045
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Inhibition of proteasome deubiquitinating activity as a new cancer therapy
Author / Creator:D'Arcy, Pádraig ; Brnjic, Slavica ; Olofsson, Maria Hägg ; Fryknäs, Mårten ; Lindsten, Kristina ; De Cesare, Michelandrea ; Perego, Paola ; Sadeghi, Behnam ; Hassan, Moustapha ; Larsson, Rolf ; Linder, Stig
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2011-12, Vol.17 (12), p.1636-1640
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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Author / Creator:Lee, Nami ; Heo, Yu Jung ; Choi, Sung-E ; Jeon, Ja Young ; Han, Seung Jin ; Kim, Dae Jung ; Kang, Yup ; Lee, Kwan Woo ; Kim, Hae Jin
Publisher:Egypt: Hindawi
Journal title:Journal of immunology research, 2021, Vol.2021, p.1-11
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Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target
Author / Creator:Saini, U ; Naidu, S ; ElNaggar, A C ; Bid, H K ; Wallbillich, J J ; Bixel, K ; Bolyard, C ; Suarez, A A ; Kaur, B ; Kuppusamy, P ; Hays, J ; Goodfellow, P J ; Cohn, D E ; Selvendiran, K
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-01, Vol.36 (2), p.168-181
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Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors
Author / Creator:Sewald, Leonard ; Tabak, Werner W. A. ; Fehr, Lorenz ; Zolg, Samuel ; Najdzion, Maja ; Verhoef, Carlo J. A. ; Podlesainski, David ; Geiss-Friedlander, Ruth ; Lammens, Alfred ; Kaschani, Farnusch ; Hellerschmied, Doris ; Huber, Robert ; Kaiser, Markus
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-04, Vol.16 (1), p.3208-15, Article 3208
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Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells
Author / Creator:He, Guodong ; Feng, Chen ; Vinothkumar, Rajamanickam ; Chen, Weiqian ; Dai, Xuanxuan ; Chen, Xi ; Ye, Qingqing ; Qiu, Chenyu ; Zhou, Huiping ; Wang, Yi ; Liang, Guang ; Xie, Yubo ; Wu, Wei
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2016-12, Vol.78 (6), p.1151-1161
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Conjugates of 3,5-Bis(arylidene)-4-piperidone and Sesquiterpene Lactones Have an Antitumor Effect via Resetting the Metabolic Phenotype of Cancer Cells
Author / Creator:Neganova, M. E. ; Aleksandrova, Yu. R. ; Sharova, E. V. ; Smirnova, E. V. ; Artyushin, O. I. ; Nikolaeva, N. S. ; Semakov, A. V. ; Schagina, I. A. ; Akylbekov, N. ; Kurmanbayev, R. ; Orynbekov, D. ; Brel, V. K.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-06, Vol.29 (12), p.2765
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Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells
Author / Creator:Razali, Nur Syahirah Che ; Lam, Kok Wai ; Rajab, Nor Fadilah ; A. Jamal, A. Rahman ; Kamaluddin, Nurul Farahana ; Chan, Kok Meng
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-07, Vol.12 (1), p.13131-17, Article 13131
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Pro-apoptotic and anti-apoptotic regulation mediated by deubiquitinating enzymes
Author / Creator:Choi, Hae-Seul ; Baek, Kwang-Hyun
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2022-02, Vol.79 (2), p.117-117, Article 117
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The curcumin analogue PAC has potent anti-anaplastic thyroid cancer effects
Author / Creator:Al-Mohanna, Mai ; Alraouji, Noura N. ; Alhabardi, Samiah A. ; Al-Mohanna, Falah ; Al-Otaibi, Basem ; Al-Jammaz, Ibrahim ; Aboussekhra, Abdelilah
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-03, Vol.13 (1), p.4217-4217, Article 4217
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The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo
Author / Creator:Yang, Chuan He ; Yue, Junming ; Sims, Michelle ; Pfeffer, Lawrence M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-08, Vol.8 (8), p.e71130
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Molecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma
Author / Creator:Silva, Rayanne H. N. ; Machado, Thaíssa Q. ; da Fonseca, Anna Carolina C. ; Tejera, Eduardo ; Perez-Castillo, Yunierkis ; Robbs, Bruno K. ; de Sousa, Damião P.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1675
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Antidiabetic effect of gemigliptin: a systematic review and meta-analysis of randomized controlled trials with Bayesian inference through a quality management system
Author / Creator:Oh, Hojin ; Nguyen, Hai Duc ; Yoon, In Mo ; Ahn, Byung-Ryong ; Kim, Min-Sun
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-10, Vol.11 (1), p.20938-19, Article 20938
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Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma
Author / Creator:Jiang, Liling ; Sun, Yuening ; Wang, Jinxiang ; He, Qingyan ; Chen, Xinmei ; Lan, Xiaoying ; Chen, Jinghong ; Dou, Q. Ping ; Shi, Xianping ; Liu, Jinbao
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2019-11, Vol.38 (1), p.453-14, Article 453
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Migrastatin analogues target fascin to block tumour metastasis
Author / Creator:Chen, Lin ; Yang, Shengyu ; Jakoncic, Jean ; Zhang, J. Jillian ; Huang, Xin-Yun
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-04, Vol.464 (7291), p.1062-1066
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NFBTA: A Potent Cytotoxic Agent against Glioblastoma
Author / Creator:Turkez, Hasan ; Nóbrega, Flávio Rogério da ; Ozdemir, Ozlem ; Bezerra Filho, Carlos da Silva Maia ; Almeida, Reinaldo Nóbrega de ; Tejera, Eduardo ; Perez-Castillo, Yunierkis ; Sousa, Damião Pergentino de
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-06, Vol.24 (13), p.2411
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EF24 (a Curcumin Analog) and ZSTK474 Emphasize the Effect of Cabozantinib in Medullary Thyroid Cancer
Author / Creator:Bertazza, Loris ; Sensi, Francesca ; Cavedon, Elisabetta ; Watutantrige-Fernando, Sara ; Censi, Simona ; Manso, Jacopo ; Vianello, Federica ; Casal Ide, Eric ; Iacobone, Maurizio ; Pezzani, Raffaele ; Mian, Caterina ; Barollo, Susi
Publisher:United States: Oxford University Press
Journal title:Endocrinology (Philadelphia), 2018-06, Vol.159 (6), p.2348-2360
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Effects of Curcumin Analogues DMC and EF24 in Combination with the Cytokine TRAIL against Kidney Cancer
Author / Creator:Ibáñez Gaspar, Verónica ; McCaul, Jasmin ; Cassidy, Hilary ; Slattery, Craig ; McMorrow, Tara
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-10, Vol.26 (20), p.6302
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Structural basis for the inhibition of the eukaryotic ribosome

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Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

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Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus

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Inhibition of proteasome deubiquitinating activity as a new cancer therapy

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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

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Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target

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Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors

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Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells

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Conjugates of 3,5-Bis(arylidene)-4-piperidone and Sesquiterpene Lactones Have an Antitumor Effect via Resetting the Metabolic Phenotype of Cancer Cells

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Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells

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Pro-apoptotic and anti-apoptotic regulation mediated by deubiquitinating enzymes

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The curcumin analogue PAC has potent anti-anaplastic thyroid cancer effects

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The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo

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Molecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma

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Antidiabetic effect of gemigliptin: a systematic review and meta-analysis of randomized controlled trials with Bayesian inference through a quality management system

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Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma

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Migrastatin analogues target fascin to block tumour metastasis

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NFBTA: A Potent Cytotoxic Agent against Glioblastoma

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EF24 (a Curcumin Analog) and ZSTK474 Emphasize the Effect of Cabozantinib in Medullary Thyroid Cancer

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Effects of Curcumin Analogues DMC and EF24 in Combination with the Cytokine TRAIL against Kidney Cancer

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