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496 results for RAG1+protein

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Contributing to the Functional Classification of Missense Variants in RAG1 Protein from Structural Perspective
Author / Creator:Kutlu, Aslı ; Işıkgil, Begüm ; Fırtına, Sinem
Journal title:Experimed, 2025-03
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Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination
Author / Creator:Um, Jee-Hyun ; Brown, Alexandra L. ; Singh, Samarendra K. ; Chen, Yong ; Gucek, Marjan ; Lee, Baeck-Seung ; Luckey, Megan A. ; Kim, Myung K. ; Park, Jung-Hyun ; Sleckman, Barry P. ; Gellert, Martin ; Chung, Jay H.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9873-9878
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Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer
Author / Creator:Salazar, Ylia ; Zheng, Xiang ; Brunn, David ; Raifer, Hartmann ; Picard, Felix ; Zhang, Yajuan ; Winter, Hauke ; Guenther, Stefan ; Weigert, Andreas ; Weigmann, Benno ; Dumoutier, Laure ; Renauld, Jean-Christophe ; Waisman, Ari ; Schmall, Anja ; Tufman, Amanda ; Fink, Ludger ; Brüne, Bernhard ; Bopp, Tobias ; Grimminger, Friedrich ; Seeger, Werner ; Pullamsetti, Soni Savai ; Huber, Magdalena ; Savai, Rajkumar
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-07, Vol.130 (7), p.3560-3575
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IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts
Author / Creator:Picard, Felix Simon Ruben ; Lutz, Veronika ; Brichkina, Anna ; Neuhaus, Felix ; Ruckenbrod, Teresa ; Hupfer, Anna ; Raifer, Hartmann ; Klein, Matthias ; Bopp, Tobias ; Pfefferle, Petra Ina ; Savai, Rajkumar ; Prinz, Immo ; Waisman, Ari ; Moos, Sonja ; Chang, Hyun-Dong ; Heinrich, Stefan ; Bartsch, Detlef K ; Buchholz, Malte ; Singh, Shiv ; Tu, Mengyu ; Klein, Lukas ; Bauer, Christian ; Liefke, Robert ; Burchert, Andreas ; Chung, Ho-Ryun ; Mayer, Philipp ; Gress, Thomas M ; Lauth, Matthias ; Gaida, Matthias ; Huber, Magdalena
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2023-08, Vol.72 (8), p.1510-1522
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Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution
Author / Creator:Efremova, Mirjana ; Rieder, Dietmar ; Klepsch, Victoria ; Charoentong, Pornpimol ; Finotello, Francesca ; Hackl, Hubert ; Hermann-Kleiter, Natascha ; Löwer, Martin ; Baier, Gottfried ; Krogsdam, Anne ; Trajanoski, Zlatko
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.32-32, Article 32
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Interleukin-17–producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity
Author / Creator:Kim, Hye Young ; Lee, Hyun Jun ; Chang, Ya-Jen ; Pichavant, Muriel ; Shore, Stephanie A ; Fitzgerald, Katherine A ; Iwakura, Yoichiro ; Israel, Elliot ; Bolger, Kenneth ; Faul, John ; DeKruyff, Rosemarie H ; Umetsu, Dale T
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2014-01, Vol.20 (1), p.54-61
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Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling
Author / Creator:Quiros, Miguel ; Nishio, Hikaru ; Neumann, Philipp A. ; Siuda, Dorothee ; Brazil, Jennifer C. ; Azcutia, Veronica ; Hilgarth, Roland ; O’Leary, Monique N. ; Garcia-Hernandez, Vicky ; Leoni, Giovanna ; Feng, Mingli ; Bernal, Gabriela ; Williams, Holly ; Dedhia, Priya H. ; Gerner-Smidt, Christian ; Spence, Jason ; Parkos, Charles A. ; Denning, Timothy L. ; Nusrat, Asma
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-09, Vol.127 (9), p.3510-3520
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An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution
Author / Creator:Liu, Benyu ; Ye, Buqing ; Zhu, Xiaoxiao ; Yang, Liuliu ; Li, Huimu ; Liu, Nian ; Zhu, Pingping ; Lu, Tiankun ; He, Luyun ; Tian, Yong ; Fan, Zusen
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4076-4076, Article 4076
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Efficient base editing for multiple genes and loci in pigs using base editors
Author / Creator:Xie, Jingke ; Ge, Weikai ; Li, Nan ; Liu, Qishuai ; Chen, Fangbing ; Yang, Xiaoyu ; Huang, Xingyun ; Ouyang, Zhen ; Zhang, Quanjun ; Zhao, Yu ; Liu, Zhaoming ; Gou, Shixue ; Wu, Han ; Lai, Chengdan ; Fan, Nana ; Jin, Qin ; Shi, Hui ; Liang, Yanhui ; Lan, Ting ; Quan, Longquan ; Li, Xiaoping ; Wang, Kepin ; Lai, Liangxue
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2852-13, Article 2852
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Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells
Author / Creator:Csomos, Krisztian ; Ujhazi, Boglarka ; Blazso, Peter ; Herrera, Jose L. ; Tipton, Christopher M. ; Kawai, Tomoki ; Gordon, Sumai ; Ellison, Maryssa ; Wu, Kevin ; Stowell, Matthew ; Haynes, Lauren ; Cruz, Rachel ; Zakota, Bence ; Nguyen, Johnny ; Altrich, Michelle ; Geier, Christoph B. ; Sharapova, Svetlana ; Dasso, Joseph F. ; Leiding, Jennifer W. ; Smith, Grace ; Al-Herz, Waleed ; de Barros Dorna, Mayra ; Fadugba, Olajumoke ; Fronkova, Eva ; Kanderova, Veronika ; Svaton, Michael ; Henrickson, Sarah E. ; Hernandez, Joseph D. ; Kuijpers, Taco ; Kandilarova, Snezhina Mihailova ; Naumova, Elizaveta ; Milota, Tomas ; Sediva, Anna ; Moshous, Despina ; Neven, Benedicte ; Saco, Tara ; Sargur, Ravishankar ; Savic, Sinisa ; Sleasman, John ; Sunkersett, Gauri ; Ward, Brant R. ; Komatsu, Masanobu ; Pittaluga, Stefania ; Kumanovics, Attila ; Butte, Manish J. ; Cancro, Michael P. ; Pillai, Shiv ; Meffre, Eric ; Notarangelo, Luigi D. ; Walter, Jolan E.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-08, Vol.23 (8), p.1256-1272
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Experimental colonization with Blastocystis ST4 is associated with protective immune responses and modulation of gut microbiome in a DSS-induced colitis mouse model
Author / Creator:Deng, Lei ; Wojciech, Lukasz ; Png, Chin Wen ; Koh, Eileen Yiling ; Aung, Thet Tun ; Kioh, Dorinda Yan Qin ; Chan, Eric Chun Yong ; Malleret, Benoit ; Zhang, Yongliang ; Peng, Guangneng ; Gascoigne, Nicholas Robert John ; Tan, Kevin Shyong Wei
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2022-05, Vol.79 (5), p.245-245, Article 245
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Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly
Author / Creator:Martínez, Inés ; Maldonado-Gomez, Maria X ; Gomes-Neto, João Carlos ; Kittana, Hatem ; Ding, Hua ; Schmaltz, Robert ; Joglekar, Payal ; Cardona, Roberto Jiménez ; Marsteller, Nathan L ; Kembel, Steven W ; Benson, Andrew K ; Peterson, Daniel A ; Ramer-Tait, Amanda E ; Walter, Jens
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2018-09, Vol.7
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Structural insights into the evolution of the RAG recombinase
Author / Creator:Liu, Chang ; Zhang, Yuhang ; Liu, Catherine C. ; Schatz, David G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2022-06, Vol.22 (6), p.353-370
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Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia
Author / Creator:Gallagher, E J ; Zelenko, Z ; Neel, B A ; Antoniou, I M ; Rajan, L ; Kase, N ; LeRoith, D
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-11, Vol.36 (46), p.6462-6471
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Resolution of inflammation-induced depression requires T lymphocytes and endogenous brain interleukin-10 signaling
Author / Creator:Laumet, Geoffroy ; Edralin, Jules Daniel ; Chiang, Angie Chi-An ; Dantzer, Robert ; Heijnen, Cobi J. ; Kavelaars, Annemieke
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2018-12, Vol.43 (13), p.2597-2605
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Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
Author / Creator:Osum, Kevin C. ; Burrack, Adam L. ; Martinov, Tijana ; Sahli, Nathanael L. ; Mitchell, Jason S. ; Tucker, Christopher G. ; Pauken, Kristen E. ; Papas, Klearchos ; Appakalai, Balamurugan ; Spanier, Justin A. ; Fife, Brian T.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-05, Vol.8 (1), p.8295-12, Article 8295
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Consensus Middle East and North Africa Registry on Inborn Errors of Immunity
Author / Creator:Aghamohammadi, Asghar ; Rezaei, Nima ; Yazdani, Reza ; Delavari, Samaneh ; Kutukculer, Necil ; Topyildiz, Ezgi ; Ozen, Ahmet ; Baris, Safa ; Karakoc-Aydiner, Elif ; Kilic, Sara Sebnem ; Kose, Hulya ; Gulez, Nesrin ; Genel, Ferah ; Reisli, Ismail ; Djenouhat, Kamel ; Tahiat, Azzeddine ; Boukari, Rachida ; Ladj, Samir ; Belbouab, Reda ; Ferhani, Yacine ; Belaid, Brahim ; Djidjik, Reda ; Kechout, Nadia ; Attal, Nabila ; Saidani, Khalissa ; Barbouche, Ridha ; Bousfiha, Aziz ; Sobh, Ali ; Rizk, Ragheed ; Elnagdy, Marwa H. ; Al-Ahmed, Mona ; Al-Tamemi, Salem ; Nasrullayeva, Gulnara ; Adeli, Mehdi ; Al-Nesf, Maryam ; Hassen, Amel ; Mehawej, Cybel ; Irani, Carla ; Megarbane, Andre ; Quinn, Jessica ; Maródi, László ; Modell, Vicki ; Modell, Fred ; Al-Herz, Waleed ; Geha, Raif S. ; Abolhassani, Hassan
Publisher:New York: Springer US
Journal title:Journal of clinical immunology, 2021-08, Vol.41 (6), p.1339-1351
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Optimizing Phylogenomics with Rapidly Evolving Long Exons: Comparison with Anchored Hybrid Enrichment and Ultraconserved Elements
Author / Creator:Karin, Benjamin R ; Gamble, Tony ; Jackman, Todd R
Publisher:Oxford: Oxford University Press
Journal title:Molecular biology and evolution, 2020-03, Vol.37 (3), p.904-922
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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells
Author / Creator:Kono, Michihito ; Yoshida, Nobuya ; Maeda, Kayaho ; Tsokos, George C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (10), p.2478-2483
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Transposon molecular domestication and the evolution of the RAG recombinase
Author / Creator:Zhang, Yuhang ; Cheng, Tat Cheung ; Huang, Guangrui ; Lu, Qingyi ; Surleac, Marius D. ; Mandell, Jeffrey D. ; Pontarotti, Pierre ; Petrescu, Andrei J. ; Xu, Anlong ; Xiong, Yong ; Schatz, David G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-05, Vol.569 (7754), p.79-84
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Contributing to the Functional Classification of Missense Variants in RAG1 Protein from Structural Perspective

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Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination

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Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer

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IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts

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Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution

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Interleukin-17–producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

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Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

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An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution

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Efficient base editing for multiple genes and loci in pigs using base editors

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Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells

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Experimental colonization with Blastocystis ST4 is associated with protective immune responses and modulation of gut microbiome in a DSS-induced colitis mouse model

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Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly

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Structural insights into the evolution of the RAG recombinase

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Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia

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Resolution of inflammation-induced depression requires T lymphocytes and endogenous brain interleukin-10 signaling

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Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes

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Consensus Middle East and North Africa Registry on Inborn Errors of Immunity

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Optimizing Phylogenomics with Rapidly Evolving Long Exons: Comparison with Anchored Hybrid Enrichment and Ultraconserved Elements

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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells

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Transposon molecular domestication and the evolution of the RAG recombinase

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