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ArticlesPeer ReviewedFull Text
NICE guidance on trastuzumab for the treatment of HER2-positive metastatic gastric cancer
Author / Creator:Holden, Joanne ; Garrett, Zoe ; Stevens, Andrew
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2011, Vol.12 (1), p.16-17
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FDA approves pertuzumab for breast cancer
Author / Creator:Traynor, Kate
Publisher:England: Oxford University Press
Journal title:American journal of health-system pharmacy, 2012-07, Vol.69 (14), p.1178-1178
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Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer
Author / Creator:Cortés, Javier ; Kim, Sung-Bae ; Chung, Wei-Pang ; Im, Seock-Ah ; Park, Yeon Hee ; Hegg, Roberto ; Kim, Min Hwan ; Tseng, Ling-Ming ; Petry, Vanessa ; Chung, Chi-Feng ; Iwata, Hiroji ; Hamilton, Erika ; Curigliano, Giuseppe ; Xu, Binghe ; Huang, Chiun-Sheng ; Kim, Jee Hyun ; Chiu, Joanne W.Y ; Pedrini, Jose Luiz ; Lee, Caleb ; Liu, Yali ; Cathcart, Jillian ; Bako, Emarjola ; Verma, Sunil ; Hurvitz, Sara A
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-03, Vol.386 (12), p.1143-1154
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Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials
Author / Creator:Bradley, Rosie ; Braybrooke, Jeremy ; Gray, Richard ; Hills, Robert ; Liu, Zulian ; Peto, Richard ; Davies, Lucy ; Dodwell, David ; McGale, Paul ; Pan, Hongchao ; Taylor, Carolyn ; Anderson, Stewart ; Gelber, Richard ; Gianni, Luca ; Jacot, William ; Joensuu, Heikki ; Moreno-Aspitia, Alvaro ; Piccart, Martine ; Press, Michael ; Romond, Edward ; Slamon, Dennis ; Suman, Vera ; Berry, Richard ; Boddington, Clare ; Clarke, Mike ; Davies, Christina ; Duane, Fran ; Evans, Vaughan ; Gay, Jo ; Gettins, Lucy ; Godwin, Jon ; James, Sam ; Liu, Hui ; MacKinnon, Elizabeth ; Mannu, Gurdeep ; McHugh, Theresa ; Morris, Philip ; Read, Simon ; Straiton, Ewan ; Wang, Yaochen ; Crown, John ; de Azambuja, Evandro ; Delaloge, Suzette ; Fung, Helena ; Geyer, Charles ; Spielmann, Marc ; Valagussa, Pinuccia ; Albain, Kathy ; Arriagada, Rodrigo ; Bartlett, John ; Bergsten-Nordström, Elizabeth ; Bliss, Judith ; Brain, Etienne ; Carey, Lisa ; Coleman, Robert ; Cuzick, Jack ; Davidson, Nancy ; Del Mastro, Lucia ; Di Leo, Angelo ; Dignam, James ; Dowsett, Mitch ; Ejlertsen, Bent ; Francis, Prue ; Gnant, Michael ; Goetz, Matthew ; Goodwin, Pam ; Halpin-Murphy, Pat ; Hayes, Dan ; Hill, Catherine ; Jagsi, Reshma ; Janni, Wolfgang ; Loibl, Sibylle ; Mamounas, Eleftherios P ; Martín, Miguel ; Mukai, Hirofumi ; Nekljudova, Valentina ; Norton, Larry ; Ohashi, Yasuo ; Pierce, Lori ; Poortmans, Philip ; Raina, Vinod ; Rea, Daniel ; Regan, Meredith ; Robertson, John ; Rutgers, Emiel ; Spanic, Tanja ; Sparano, Joseph ; Steger, Guenther ; Tang, Gong ; Toi, Masakazu ; Tutt, Andrew ; Viale, Giuseppe ; Wang, Xiang ; Whelan, Tim ; Wilcken, Nicholas ; Wolmark, Norman ; Cameron, David ; Bergh, Jonas ; Pritchard, Kathleen I ; Swain, Sandra M
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2021-08, Vol.22 (8), p.1139-1150
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Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer
Author / Creator:Murthy, Rashmi K ; Loi, Sherene ; Okines, Alicia ; Paplomata, Elisavet ; Hamilton, Erika ; Hurvitz, Sara A ; Lin, Nancy U ; Borges, Virginia ; Abramson, Vandana ; Anders, Carey ; Bedard, Philippe L ; Oliveira, Mafalda ; Jakobsen, Erik ; Bachelot, Thomas ; Shachar, Shlomit S ; Müller, Volkmar ; Braga, Sofia ; Duhoux, Francois P ; Greil, Richard ; Cameron, David ; Carey, Lisa A ; Curigliano, Giuseppe ; Gelmon, Karen ; Hortobagyi, Gabriel ; Krop, Ian ; Loibl, Sibylle ; Pegram, Mark ; Slamon, Dennis ; Palanca-Wessels, M. Corinna ; Walker, Luke ; Feng, Wentao ; Winer, Eric P
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-02, Vol.382 (7), p.597-609
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ArticlesPeer ReviewedFull Text
Gastric cancer
Author / Creator:Van Cutsem, Eric, Prof ; Sagaert, Xavier, MD ; Topal, Baki, Prof ; Haustermans, Karin, Prof ; Prenen, Hans, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-11, Vol.388 (10060), p.2654-2664
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ArticlesPeer ReviewedFull Text
Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer
Author / Creator:Modi, Shanu ; Saura, Cristina ; Yamashita, Toshinari ; Park, Yeon Hee ; Kim, Sung-Bae ; Tamura, Kenji ; Andre, Fabrice ; Iwata, Hiroji ; Ito, Yoshinori ; Tsurutani, Junji ; Sohn, Joohyuk ; Denduluri, Neelima ; Perrin, Christophe ; Aogi, Kenjiro ; Tokunaga, Eriko ; Im, Seock-Ah ; Lee, Keun Seok ; Hurvitz, Sara A ; Cortes, Javier ; Lee, Caleb ; Chen, Shuquan ; Zhang, Lin ; Shahidi, Javad ; Yver, Antoine ; Krop, Ian
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-02, Vol.382 (7), p.610-621
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ArticlesPeer ReviewedFull Text
The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer
Author / Creator:Janjigian, Yelena Y. ; Kawazoe, Akihito ; Yañez, Patricio ; Li, Ning ; Lonardi, Sara ; Kolesnik, Oleksii ; Barajas, Olga ; Bai, Yuxian ; Shen, Lin ; Tang, Yong ; Wyrwicz, Lucjan S. ; Xu, Jianming ; Shitara, Kohei ; Qin, Shukui ; Van Cutsem, Eric ; Tabernero, Josep ; Li, Lie ; Shah, Sukrut ; Bhagia, Pooja ; Chung, Hyun Cheol
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-12, Vol.600 (7890), p.727-730
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ArticlesPeer ReviewedFull Text
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-l...
Author / Creator:Sartore-Bianchi, Andrea, MD ; Trusolino, Livio, MD ; Martino, Cosimo, PhD ; Bencardino, Katia, MD ; Lonardi, Sara, MD ; Bergamo, Francesca, MD ; Zagonel, Vittorina, MD ; Leone, Francesco, MD ; Depetris, Ilaria, MD ; Martinelli, Erika, MD ; Troiani, Teresa, MD ; Ciardiello, Fortunato, Prof ; Racca, Patrizia, MD ; Bertotti, Andrea, MD ; Siravegna, Giulia, MSc ; Torri, Valter, MD ; Amatu, Alessio, MD ; Ghezzi, Silvia, MSc ; Marrapese, Giovanna, PhD ; Palmeri, Laura, MD ; Valtorta, Emanuele, PhD ; Cassingena, Andrea, MSc ; Lauricella, Calogero, PhD ; Vanzulli, Angelo, MD ; Regge, Daniele, MD ; Veronese, Silvio, MSc ; Comoglio, Paolo M, Prof ; Bardelli, Alberto, PhD ; Marsoni, Silvia, Dr ; Siena, Salvatore, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.738-746
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ArticlesPeer ReviewedFull Text
Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative stu...
Author / Creator:Rugo, Hope S ; Lerebours, Florence ; Ciruelos, Eva ; Drullinsky, Pamela ; Ruiz-Borrego, Manuel ; Neven, Patrick ; Park, Yeon Hee ; Prat, Aleix ; Bachelot, Thomas ; Juric, Dejan ; Turner, Nicholas ; Sophos, Nickolas ; Zarate, Juan Pablo ; Arce, Christina ; Shen, Yu-Ming ; Turner, Stuart ; Kanakamedala, Hemanth ; Hsu, Wei-Chun ; Chia, Stephen
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2021-04, Vol.22 (4), p.489-498
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ArticlesPeer ReviewedFull Text
HER kinase inhibition in patients with HER2- and HER3-mutant cancers
Author / Creator:Hyman, David M. ; Piha-Paul, Sarina A. ; Won, Helen ; Rodon, Jordi ; Saura, Cristina ; Shapiro, Geoffrey I. ; Juric, Dejan ; Quinn, David I. ; Moreno, Victor ; Doger, Bernard ; Mayer, Ingrid A. ; Boni, Valentina ; Calvo, Emiliano ; Loi, Sherene ; Lockhart, Albert C. ; Erinjeri, Joseph P. ; Scaltriti, Maurizio ; Ulaner, Gary A. ; Patel, Juber ; Tang, Jiabin ; Beer, Hannah ; Selcuklu, S. Duygu ; Hanrahan, Aphrothiti J. ; Bouvier, Nancy ; Melcer, Myra ; Murali, Rajmohan ; Schram, Alison M. ; Smyth, Lillian M. ; Jhaveri, Komal ; Li, Bob T. ; Drilon, Alexander ; Harding, James J. ; Iyer, Gopa ; Taylor, Barry S. ; Berger, Michael F. ; Cutler Jr, Richard E. ; Xu, Feng ; Butturini, Anna ; Eli, Lisa D. ; Mann, Grace ; Farrell, Cynthia ; Lalani, Alshad S. ; Bryce, Richard P. ; Arteaga, Carlos L. ; Meric-Bernstam, Funda ; Baselga, José ; Solit, David B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-02, Vol.554 (7691), p.189-194
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ArticlesPeer ReviewedFull Text
Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase...
Author / Creator:Tabernero, Josep ; Hoff, Paulo M ; Shen, Lin ; Ohtsu, Atsushi ; Shah, Manish A ; Cheng, Karen ; Song, Chunyan ; Wu, Haiyan ; Eng-Wong, Jennifer ; Kim, Katherine ; Kang, Yoon-Koo
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-10, Vol.19 (10), p.1372-1384
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First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial
Author / Creator:Janjigian, Yelena Y, MD ; Maron, Steven B, MD ; Chatila, Walid K, MS ; Millang, Brittanie, MPH ; Chavan, Shweta S, PhD ; Alterman, Carly, BA ; Chou, Joanne F, MPH ; Segal, Michal F, RN ; Simmons, Marc Z, MD ; Momtaz, Parisa, MD ; Shcherba, Marina, MD ; Ku, Geoffrey Y, MD ; Zervoudakis, Alice, MD ; Won, Elizabeth S, MD ; Kelsen, David P, Prof ; Ilson, David H, Prof ; Nagy, Rebecca J, MS ; Lanman, Richard B, MD ; Ptashkin, Ryan N, MS ; Donoghue, Mark T A, PhD ; Capanu, Marinela, PhD ; Taylor, Barry S, PhD ; Solit, David B, Prof ; Schultz, Nikolaus, PhD ; Hechtman, Jaclyn F, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-06, Vol.21 (6), p.821-831
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HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer (PAMELA): an open-label, sing...
Author / Creator:Llombart-Cussac, Antonio, MD ; Cortés, Javier, MD ; Paré, Laia, PhD ; Galván, Patricia, BS ; Bermejo, Begoña, MD ; Martínez, Noelia, MD ; Vidal, Maria, MD ; Pernas, Sònia, MD ; López, Rafael, MD ; Muñoz, Montserrat, MD ; Nuciforo, Paolo, MD ; Morales, Serafín, MD ; Oliveira, Mafalda, MD ; de la Peña, Lorena, PhD ; Peláez, Alexandra, MD ; Prat, Aleix, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-04, Vol.18 (4), p.545-554
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Implementing antibody-drug conjugates (ADCs) in HER2-positive breast cancer: state of the art and future directions
Author / Creator:Ferraro, Emanuela ; Drago, Joshua Z. ; Modi, Shanu
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2021-08, Vol.23 (1), p.84-84, Article 84
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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
Author / Creator:Swain, Sandra M, Dr ; Kim, Sung-Bae, MD ; Cortés, Javier, MD ; Ro, Jungsil, MD ; Semiglazov, Vladimir, MD ; Campone, Mario, MD ; Ciruelos, Eva, MD ; Ferrero, Jean-Marc, MD ; Schneeweiss, Andreas, MD ; Knott, Adam, PhD ; Clark, Emma, MSc ; Ross, Graham, FFPM ; Benyunes, Mark C, MD ; Baselga, José, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-05, Vol.14 (6), p.461-471
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Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
Author / Creator:Baselga, José ; Cortés, Javier ; Kim, Sung-Bae ; Im, Young-Hyuck ; Im, Seock-Ah ; Hegg, Roberto ; Roman, Laslo ; Pedrini, José Luiz ; Pienkowski, Tadeusz ; Knott, Adam ; Clark, Emma ; Benyunes, Mark C ; Ross, Graham ; Swain, Sandra M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2012-01, Vol.366 (2), p.109-119
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Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phas...
Author / Creator:Gianni, Luca, Dr ; Pienkowski, Tadeusz, Prof ; Im, Young-Hyuck, Prof ; Roman, Laslo, MD ; Tseng, Ling-Ming, MD ; Liu, Mei-Ching, MD ; Lluch, Ana, MD ; Staroslawska, Elżbieta, Prof ; de la Haba-Rodriguez, Juan, MD ; Im, Seock-Ah, Prof ; Pedrini, Jose Luiz, MD ; Poirier, Brigitte, MD ; Morandi, Paolo, MD ; Semiglazov, Vladimir, Prof ; Srimuninnimit, Vichien, Prof ; Bianchi, Giulia, MD ; Szado, Tania, PhD ; Ratnayake, Jayantha, BSc ; Ross, Graham, MD ; Valagussa, Pinuccia, BS
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012, Vol.13 (1), p.25-32
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Towards personalized treatment for early stage HER2-positive breast cancer
Author / Creator:Goutsouliak, Kristina ; Veeraraghavan, Jamunarani ; Sethunath, Vidyalakshmi ; De Angelis, Carmine ; Osborne, C. Kent ; Rimawi, Mothaffar F. ; Schiff, Rachel
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2020-04, Vol.17 (4), p.233-250
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Cancer immunotherapy comes of age and looks for maturity
Author / Creator:Finck, Amanda ; Gill, Saar I. ; June, Carl H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-07, Vol.11 (1), p.3325-3325, Article 3325
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Showing 1 to 20 of 799 results

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NICE guidance on trastuzumab for the treatment of HER2-positive metastatic gastric cancer

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FDA approves pertuzumab for breast cancer

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Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer

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Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials

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Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer

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Gastric cancer

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Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer

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The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer

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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-l...

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Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative stu...

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HER kinase inhibition in patients with HER2- and HER3-mutant cancers

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Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase...

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First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial

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HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer (PAMELA): an open-label, sing...

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Implementing antibody-drug conjugates (ADCs) in HER2-positive breast cancer: state of the art and future directions

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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study

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Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer

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Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phas...

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Towards personalized treatment for early stage HER2-positive breast cancer

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Cancer immunotherapy comes of age and looks for maturity

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