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ArticlesPeer ReviewedFull Text
Alternative lengthening of telomeres: models, mechanisms and implications
Author / Creator:Cesare, Anthony J. ; Reddel, Roger R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2010-05, Vol.11 (5), p.319-330
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Molecular mechanisms of activity and derepression of alternative lengthening of telomeres
Author / Creator:Pickett, Hilda A ; Reddel, Roger R
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2015-11, Vol.22 (11), p.875-880
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ArticlesPeer ReviewedFull Text
Alternative lengthening of telomeres is not synonymous with mutations in ATRX/DAXX
Author / Creator:de Nonneville, Alexandre ; Reddel, Roger R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1552-1552, Article 1552
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The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
Author / Creator:Lu, Robert ; O’Rourke, Julienne J. ; Sobinoff, Alexander P. ; Allen, Joshua A. M. ; Nelson, Christopher B. ; Tomlinson, Christopher G. ; Lee, Michael ; Reddel, Roger R. ; Deans, Andrew J. ; Pickett, Hilda A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-05, Vol.10 (1), p.2252-14, Article 2252
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ArticlesPeer ReviewedFull Text
Cancer and Telomeres—An ALTernative to Telomerase
Author / Creator:Shay, Jerry W. ; Reddel, Roger R. ; Wright, Woodring E.
Publisher:Washington: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-06, Vol.336 (6087), p.1388-1390
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ArticlesPeer ReviewedFull Text
Five dysfunctional telomeres predict onset of senescence in human cells
Author / Creator:Kaul, Zeenia ; Cesare, Anthony J ; Huschtscha, Lily I ; Neumann, Axel A ; Reddel, Roger R
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:EMBO reports, 2012-01, Vol.13 (1), p.52-59
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ArticlesPeer ReviewedFull Text
Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells
Author / Creator:Cao, Ying ; Bryan, Tracy M. ; Reddel, Roger R.
Publisher:Melbourne, Australia: Blackwell Publishing Asia
Journal title:Cancer science, 2008-06, Vol.99 (6), p.1092-1099
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ArticlesPeer ReviewedFull Text
Strategies to enable large-scale proteomics for reproducible research
Author / Creator:Poulos, Rebecca C. ; Hains, Peter G. ; Shah, Rohan ; Lucas, Natasha ; Xavier, Dylan ; Manda, Srikanth S. ; Anees, Asim ; Koh, Jennifer M. S. ; Mahboob, Sadia ; Wittman, Max ; Williams, Steven G. ; Sykes, Erin K. ; Hecker, Michael ; Dausmann, Michael ; Wouters, Merridee A. ; Ashman, Keith ; Yang, Jean ; Wild, Peter J. ; deFazio, Anna ; Balleine, Rosemary L. ; Tully, Brett ; Aebersold, Ruedi ; Speed, Terence P. ; Liu, Yansheng ; Reddel, Roger R. ; Robinson, Phillip J. ; Zhong, Qing
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-07, Vol.11 (1), p.3793-3793, Article 3793
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Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
Author / Creator:Lovejoy, Courtney A. ; Li, Wendi ; Reisenweber, Steven ; Thongthip, Supawat ; Bruno, Joanne ; de Lange, Titia ; De, Saurav ; Petrini, John H. J. ; Sung, Patricia A. ; Jasin, Maria ; Rosenbluh, Joseph ; Zwang, Yaara ; Weir, Barbara A. ; Hatton, Charlie ; Ivanova, Elena ; Macconaill, Laura ; Hanna, Megan ; Hahn, William C. ; Lue, Neal F. ; Reddel, Roger R. ; Jiao, Yuchen ; Kinzler, Kenneth ; Vogelstein, Bert ; Papadopoulos, Nickolas ; Meeker, Alan K.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2012-07, Vol.8 (7), p.e1002772-e1002772
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ArticlesPeer ReviewedFull Text
Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning
Author / Creator:Cai, Zhaoxiang ; Apolinário, Sofia ; Baião, Ana R. ; Pacini, Clare ; Sousa, Miguel D. ; Vinga, Susana ; Reddel, Roger R. ; Robinson, Phillip J. ; Garnett, Mathew J. ; Zhong, Qing ; Gonçalves, Emanuel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.10390-12, Article 10390
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ArticlesPeer ReviewedFull Text
Protein Composition of Catalytically Active Human Telomerase from Immortal Cells
Author / Creator:Cohen, Scott B ; Graham, Mark E ; Lovrecz, George O ; Bache, Nicolai ; Robinson, Phillip J ; Reddel, Roger R
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2007-03, Vol.315 (5820), p.1850-1853
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Author Correction: Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning
Author / Creator:Cai, Zhaoxiang ; Apolinário, Sofia ; Baião, Ana R. ; Pacini, Clare ; Sousa, Miguel D. ; Vinga, Susana ; Reddel, Roger R. ; Robinson, Phillip J. ; Garnett, Mathew J. ; Zhong, Qing ; Gonçalves, Emanuel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1352-1, Article 1352
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ArticlesPeer ReviewedFull Text
Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions
Author / Creator:Cesare, Anthony J ; Kaul, Zeenia ; Cohen, Scott B ; Napier, Christine E ; Pickett, Hilda A ; Neumann, Axel A ; Reddel, Roger R
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2009-12, Vol.16 (12), p.1244-1251
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ArticlesPeer ReviewedFull Text
CRISPR screens identify gene targets at breast cancer risk loci
Author / Creator:Tuano, Natasha K. ; Beesley, Jonathan ; Manning, Murray ; Shi, Wei ; Perlaza-Jimenez, Laura ; Malaver-Ortega, Luis F. ; Paynter, Jacob M. ; Black, Debra ; Civitarese, Andrew ; McCue, Karen ; Hatzipantelis, Aaron ; Hillman, Kristine ; Kaufmann, Susanne ; Sivakumaran, Haran ; Polo, Jose M. ; Reddel, Roger R. ; Band, Vimla ; French, Juliet D. ; Edwards, Stacey L. ; Powell, David R. ; Chenevix-Trench, Georgia ; Rosenbluh, Joseph
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2023-03, Vol.24 (1), p.59-59, Article 59
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TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT
Author / Creator:de Nonneville, Alexandre ; Salas, Sébastien ; Bertucci, François ; Sobinoff, Alexander P ; Adélaïde, José ; Guille, Arnaud ; Finetti, Pascal ; Noble, Jane R ; Churikov, Dimitri ; Chaffanet, Max ; Lavit, Elise ; Pickett, Hilda A ; Bouvier, Corinne ; Birnbaum, Daniel ; Reddel, Roger R ; Géli, Vincent
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2022-10, Vol.14 (10), p.e15859-n/a
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A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase
Author / Creator:Killedar, Anagha ; Stutz, Michael D. ; Sobinoff, Alexander P. ; Tomlinson, Christopher G. ; Bryan, Tracy M. ; Beesley, Jonathan ; Chenevix-Trench, Georgia ; Reddel, Roger R. ; Pickett, Hilda A.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-06, Vol.11 (6), p.e1005286-e1005286
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ArticlesPeer ReviewedFull Text
MatCol: a tool to measure fluorescence signal colocalisation in biological systems
Author / Creator:Khushi, Matloob ; Napier, Christine E. ; Smyth, Christine M. ; Reddel, Roger R. ; Arthur, Jonathan W.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.8879-9, Article 8879
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Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells
Author / Creator:Kaul, Zeenia ; Cheung, Caroline T. Y. ; Bhargava, Priyanshu ; Sari, Anissa Notifa ; Yu, Yue ; Huifu, He ; Bid, Hemant ; Henson, Jeremy D. ; Groden, Joanna ; Reddel, Roger R. ; Kaul, Sunil C. ; Wadhwa, Renu
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-08, Vol.11 (1), p.17052-19, Article 17052
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Retrospective analysis of clinical characteristics and outcomes of patients with carcinoma of unknown primary from three tertiary centers in Australia
Author / Creator:Boys, Emma L. ; Gao, Bo ; Grimison, Peter ; Sutherland, Sarah ; MacKenzie, Karen L. ; Reddel, Roger R. ; Liu, Jia
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2024-03, Vol.13 (6), p.e7052-n/a
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Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres
Author / Creator:Bower, Kylie ; Napier, Christine E. ; Cole, Sara L. ; Dagg, Rebecca A. ; Lau, Loretta M. S. ; Duncan, Emma L. ; Moy, Elsa L. ; Reddel, Roger R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e50062-e50062
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Showing 1 to 20 of 65 results

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Alternative lengthening of telomeres: models, mechanisms and implications

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Molecular mechanisms of activity and derepression of alternative lengthening of telomeres

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Alternative lengthening of telomeres is not synonymous with mutations in ATRX/DAXX

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The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

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Cancer and Telomeres—An ALTernative to Telomerase

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Five dysfunctional telomeres predict onset of senescence in human cells

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Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

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Strategies to enable large-scale proteomics for reproducible research

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Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

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Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning

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Protein Composition of Catalytically Active Human Telomerase from Immortal Cells

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Author Correction: Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning

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Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions

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CRISPR screens identify gene targets at breast cancer risk loci

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TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT

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A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

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MatCol: a tool to measure fluorescence signal colocalisation in biological systems

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Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells

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Retrospective analysis of clinical characteristics and outcomes of patients with carcinoma of unknown primary from three tertiary centers in Australia

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Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres

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