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227 results for Sarcoma,+Ewing+-+metabolism

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ArticlesPeer ReviewedFull Text
EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
Author / Creator:Gorthi, Aparna ; Romero, July Carolina ; Loranc, Eva ; Cao, Lin ; Lawrence, Liesl A. ; Goodale, Elicia ; Iniguez, Amanda Balboni ; Bernard, Xavier ; Masamsetti, V. Pragathi ; Roston, Sydney ; Lawlor, Elizabeth R. ; Toretsky, Jeffrey A. ; Stegmaier, Kimberly ; Lessnick, Stephen L. ; Chen, Yidong ; Bishop, Alexander J. R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-03, Vol.555 (7696), p.387-391
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Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells
Author / Creator:Franzetti, G-A ; Laud-Duval, K ; van der Ent, W ; Brisac, A ; Irondelle, M ; Aubert, S ; Dirksen, U ; Bouvier, C ; de Pinieux, G ; Snaar-Jagalska, E ; Chavrier, P ; Delattre, O
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-06, Vol.36 (25), p.3505-3514
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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
Author / Creator:Ross, Nathan T. ; Lohmann, Felix ; Carbonneau, Seth ; Fazal, Aleem ; Weihofen, Wilhelm A. ; Gleim, Scott ; Salcius, Michael ; Sigoillot, Frederic ; Henault, Martin ; Carl, Sarah H. ; Rodríguez-Molina, Juan B. ; Miller, Howard R. ; Brittain, Scott M. ; Murphy, Jason ; Zambrowski, Mark ; Boynton, Geoffrey ; Wang, Yuan ; Chen, Aye ; Molind, Gregory J. ; Wilbertz, Johannes H. ; Artus-Revel, Caroline G. ; Jia, Min ; Akinjiyan, Favour A. ; Turner, Jonathan ; Knehr, Judith ; Carbone, Walter ; Schuierer, Sven ; Reece-Hoyes, John S. ; Xie, Kevin ; Saran, Chitra ; Williams, Eric T. ; Roma, Guglielmo ; Spencer, Matt ; Jenkins, Jeremy ; George, Elizabeth L. ; Thomas, Jason R. ; Michaud, Gregory ; Schirle, Markus ; Tallarico, John ; Passmore, Lori A. ; Chao, Jeffrey A. ; Beckwith, Rohan E. J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2020-01, Vol.16 (1), p.50-59
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ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation
Author / Creator:Gao, Yuan ; He, Xue-Yan ; Wu, Xiaoli S. ; Huang, Yu-Han ; Toneyan, Shushan ; Ha, Taehoon ; Ipsaro, Jonathan J. ; Koo, Peter K. ; Joshua-Tor, Leemor ; Bailey, Kelly M. ; Egeblad, Mikala ; Vakoc, Christopher R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2023-02, Vol.25 (2), p.298-308
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Evaluation of ETV4 and WT1 expression in CIC-rearranged sarcomas and histologic mimics
Author / Creator:Hung, Yin P ; Fletcher, Christopher DM ; Hornick, Jason L
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2016-11, Vol.29 (11), p.1324-1334
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Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway
Author / Creator:Beauchamp, Elspeth M. ; Ringer, Lymor ; Bulut, Gülay ; Sajwan, Kamal P. ; Hall, Michael D. ; Lee, Yi-Chien ; Peaceman, Daniel ; Özdemirli, Metin ; Rodriguez, Olga ; Macdonald, Tobey J. ; Albanese, Chris ; Toretsky, Jeffrey A. ; Üren, Aykut
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-01, Vol.121 (1), p.148-160
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Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations
Author / Creator:Nanni, Patrizia ; Landuzzi, Lorena ; Manara, Maria Cristina ; Righi, Alberto ; Nicoletti, Giordano ; Cristalli, Camilla ; Pasello, Michela ; Parra, Alessandro ; Carrabotta, Marianna ; Ferracin, Manuela ; Palladini, Arianna ; Ianzano, Marianna L. ; Giusti, Veronica ; Ruzzi, Francesca ; Magnani, Mauro ; Donati, Davide Maria ; Picci, Piero ; Lollini, Pier-Luigi ; Scotlandi, Katia
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-08, Vol.9 (1), p.12174-12, Article 12174
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Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma
Author / Creator:Santoro, Marco ; Lamhamedi-Cherradi, Salah-Eddine ; Menegaz, Brian A. ; Ludwig, Joseph A. ; Mikos, Antonios G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (33), p.10304-10309
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Prion-like domain mediated phase separation of ARID1A promotes oncogenic potential of Ewing’s sarcoma
Author / Creator:Kim, Yong Ryoul ; Joo, Jaegeon ; Lee, Hee Jung ; Kim, Chaelim ; Park, Ju-Chan ; Yu, Young Suk ; Kim, Chang Rok ; Lee, Do Hui ; Cha, Joowon ; Kwon, Hyemin ; Hanssen, Kimberley M. ; Grünewald, Thomas G. P. ; Choi, Murim ; Han, Ilkyu ; Bae, Sangsu ; Jung, Inkyung ; Shin, Yongdae ; Baek, Sung Hee
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.6569-18, Article 6569
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Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
Author / Creator:Ruzanov, Peter ; Evdokimova, Valentina ; Pachva, Manideep C. ; Minkovich, Alon ; Zhang, Zhenbo ; Langman, Sofya ; Gassmann, Hendrik ; Thiel, Uwe ; Orlic-Milacic, Marija ; Zaidi, Syed H. ; Peltekova, Vanya ; Heisler, Lawrence E. ; Sharma, Manju ; Cox, Michael E. ; McKee, Trevor D. ; Zaidi, Mark ; Lapouble, Eve ; McPherson, John D. ; Delattre, Olivier ; Radvanyi, Laszlo ; Burdach, Stefan E.G. ; Stein, Lincoln D. ; Sorensen, Poul H.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-05, Vol.134 (9), p.1-15
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Identification of ENO‐1 positive extracellular vesicles as a circulating biomarker for monitoring of Ewing sarcoma
Author / Creator:Uotani, Koji ; Fujiwara, Tomohiro ; Ueda, Koji ; Yoshida, Aki ; Iwata, Shintaro ; Morita, Takuya ; Kiyono, Masahiro ; Kunisada, Toshiyuki ; Takeda, Ken ; Hasei, Joe ; Yoshioka, Yusuke ; Ochiya, Takahiro ; Ozaki, Toshifumi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2024-11, Vol.115 (11), p.3660-3671
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Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex
Author / Creator:Mo, Jialin ; Tan, Kezhe ; Dong, Yu ; Lu, Wenjie ; Liu, Fang ; Mei, Yanqing ; Huang, Hongting ; Zhao, Kewen ; Lv, Zhibao ; Ye, Youqiong ; Tang, Yujie
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2023-01, Vol.42 (1), p.11-25
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EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma
Author / Creator:Charville, Gregory W ; Wang, Wei-Lien ; Ingram, Davis R ; Roy, Angshumoy ; Thomas, Dafydd ; Patel, Rajiv M ; Hornick, Jason L ; van de Rijn, Matt ; Lazar, Alexander J
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2017-09, Vol.30 (9), p.1312-1320
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Tyrosine kinase inhibitors in Ewing’s sarcoma: a systematic review
Author / Creator:Assi, Ahmad ; Farhat, Mohamad ; Mohanna, Rami ; Hachem, Maria Catherine Rita ; Zalaquett, Ziad ; Aoun, Marven ; Farraj, Sami Abi ; Daher, Mohammad ; Sebaaly, Amer ; Kourie, Hampig-Raphaël
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2025-04, Vol.25 (1), p.735-14, Article 735
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EWS-FLI1-mediated tenascin-C expression promotes tumour progression by targeting MALAT1 through integrin α5β1-mediated YAP activation in Ewing sarcoma
Author / Creator:He, Shaohui ; Huang, Quan ; Hu, Jinbo ; Li, Lei ; Xiao, Yanbin ; Yu, Hongyu ; Han, Zhitao ; Wang, Ting ; Zhou, Wang ; Wei, Haifeng ; Xiao, Jianru
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2019-11, Vol.121 (11), p.922-933
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Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies
Author / Creator:Knott, Maximilian M. L. ; Hölting, Tilman L. B. ; Ohmura, Shunya ; Kirchner, Thomas ; Cidre-Aranaz, Florencia ; Grünewald, Thomas G. P.
Publisher:New York: Springer US
Journal title:Cancer and metastasis reviews, 2019-12, Vol.38 (4), p.625-642
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The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis
Author / Creator:Sechler, M ; Parrish, J K ; Birks, D K ; Jedlicka, P
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-07, Vol.36 (29), p.4150-4160
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Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-β-catenin pathway activation in Ewing sarcoma
Author / Creator:Shirai, Ryota ; Biebighauser, Tyler ; Walker, Deandra ; Oviedo, Jillian ; Nelson-Taylor, Sarah ; Bodlak, Avery ; Porfilio, Timothy ; Oike, Naoki ; Goodspeed, Andrew ; Hayashi, Masanori
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-06, Vol.19 (6), p.e0305490
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Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer
Author / Creator:Li, Jing ; Ohmura, Shunya ; Marchetto, Aruna ; Orth, Martin F. ; Imle, Roland ; Dallmayer, Marlene ; Musa, Julian ; Knott, Maximilian M. L. ; Hölting, Tilman L. B. ; Stein, Stefanie ; Funk, Cornelius M. ; Sastre, Ana ; Alonso, Javier ; Bestvater, Felix ; Kasan, Merve ; Romero-Pérez, Laura ; Hartmann, Wolfgang ; Ranft, Andreas ; Banito, Ana ; Dirksen, Uta ; Kirchner, Thomas ; Cidre-Aranaz, Florencia ; Grünewald, Thomas G. P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5356-5356, Article 5356
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Ganglioside SSEA-4 in Ewing sarcoma marks a tumor cell population with aggressive features and is a potential cell-surface immune target
Author / Creator:Jamitzky, Silke ; Altvater, Bianca ; Krekeler, Carolin ; Hoen, Laura ; Brandes, Caroline ; Ebbinghaus, Julia ; Richter, Lisa ; Kosel, Lisa ; Ochs, Laurin ; Farwick, Nicole ; Urban, Katja ; Kluge, Lena ; Bücker, Lara ; Görlich, Dennis ; Johnston, Ian C. D. ; Pfeifer, Rita ; Hartmann, Wolfgang ; Rossig, Claudia ; Kailayangiri, Sareetha
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-05, Vol.14 (1), p.11935-11935, Article 11935
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Showing 1 to 20 of 227 results

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EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

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Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells

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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

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ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation

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Evaluation of ETV4 and WT1 expression in CIC-rearranged sarcomas and histologic mimics

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Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

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Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations

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Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma

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Prion-like domain mediated phase separation of ARID1A promotes oncogenic potential of Ewing’s sarcoma

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Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles

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Identification of ENO‐1 positive extracellular vesicles as a circulating biomarker for monitoring of Ewing sarcoma

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Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex

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EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma

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Tyrosine kinase inhibitors in Ewing’s sarcoma: a systematic review

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EWS-FLI1-mediated tenascin-C expression promotes tumour progression by targeting MALAT1 through integrin α5β1-mediated YAP activation in Ewing sarcoma

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Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies

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The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis

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Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-β-catenin pathway activation in Ewing sarcoma

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Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer

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Ganglioside SSEA-4 in Ewing sarcoma marks a tumor cell population with aggressive features and is a potential cell-surface immune target

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