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ArticlesPeer ReviewedFull Text
A swapped genetic code prevents viral infections and gene transfer
Author / Creator:Nyerges, Akos ; Vinke, Svenja ; Flynn, Regan ; Owen, Siân V. ; Rand, Eleanor A. ; Budnik, Bogdan ; Keen, Eric ; Narasimhan, Kamesh ; Marchand, Jorge A. ; Baas-Thomas, Maximilien ; Liu, Min ; Chen, Kangming ; Chiappino-Pepe, Anush ; Hu, Fangxiang ; Baym, Michael ; Church, George M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-03, Vol.615 (7953), p.720-727
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PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress
Author / Creator:Ranek, Mark J. ; Kokkonen-Simon, Kristen M. ; Chen, Anna ; Dunkerly-Eyring, Brittany L. ; Vera, Miguel Pinilla ; Oeing, Christian U. ; Patel, Chirag H. ; Nakamura, Taishi ; Zhu, Guangshuo ; Bedja, Djahida ; Sasaki, Masayuki ; Holewinski, Ronald J. ; Van Eyk, Jennifer E. ; Powell, Jonathan D. ; Lee, Dong Ik ; Kass, David A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-02, Vol.566 (7743), p.264-269
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ArticlesPeer ReviewedFull Text
Natural Variation Underlies Differences in ETHYLENE RESPONSE FACTOR17 Activity in Fruit Peel Degreening
Author / Creator:Han, Zhenyun ; Hu, Yanan ; Lv, Yuanda ; Rose, Jocelyn K.C. ; Sun, Yaqiang ; Shen, Fei ; Wang, Yi ; Zhang, Xinzhong ; Xu, Xuefeng ; Wu, Ting ; Han, Zhenhai
Publisher:United States: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2018-03, Vol.176 (3), p.2292-2304
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ArticlesPeer ReviewedFull Text
LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
Author / Creator:Matta, Samer ; Van Kolen, Kristof ; da Cunha, Raquel ; van den Bogaart, Geert ; Mandemakers, Wim ; Miskiewicz, Katarzyna ; De Bock, Pieter-Jan ; Morais, Vanessa A. ; Vilain, Sven ; Haddad, Dominik ; Delbroek, Lore ; Swerts, Jef ; Chávez-Gutiérrez, Lucía ; Esposito, Giovanni ; Daneels, Guy ; Karran, Eric ; Holt, Matthew ; Gevaert, Kris ; Moechars, Diederik W. ; De Strooper, Bart ; Verstreken, Patrik
Publisher:United States: Elsevier Inc
Journal title:Neuron (Cambridge, Mass.), 2012-09, Vol.75 (6), p.1008-1021
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A single mutation in the prM protein of Zika virus contributes to fetal microcephaly
Author / Creator:Yuan, Ling ; Huang, Xing-Yao ; Liu, Zhong-Yu ; Zhang, Feng ; Zhu, Xing-Liang ; Yu, Jiu-Yang ; Ji, Xue ; Xu, Yan-Peng ; Li, Guanghui ; Li, Cui ; Wang, Hong-Jiang ; Deng, Yong-Qiang ; Wu, Menghua ; Cheng, Meng-Li ; Ye, Qing ; Xie, Dong-Yang ; Li, Xiao-Feng ; Wang, Xiangxi ; Shi, Weifeng ; Hu, Baoyang ; Shi, Pei-Yong ; Xu, Zhiheng ; Qin, Cheng-Feng
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-11, Vol.358 (6365), p.933-936
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Coactivator condensation at super-enhancers links phase separation and gene control
Author / Creator:Sabari, Benjamin R ; Dall'Agnese, Alessandra ; Boija, Ann ; Klein, Isaac A ; Coffey, Eliot L ; Shrinivas, Krishna ; Abraham, Brian J ; Hannett, Nancy M ; Zamudio, Alicia V ; Manteiga, John C ; Li, Charles H ; Guo, Yang E ; Day, Daniel S ; Schuijers, Jurian ; Vasile, Eliza ; Malik, Sohail ; Hnisz, Denes ; Lee, Tong Ihn ; Cisse, Ibrahim I ; Roeder, Robert G ; Sharp, Phillip A ; Chakraborty, Arup K ; Young, Richard A
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-07, Vol.361 (6400)
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Comprehensive characterization of protein–protein interactions perturbed by disease mutations
Author / Creator:Cheng, Feixiong ; Zhao, Junfei ; Wang, Yang ; Lu, Weiqiang ; Liu, Zehui ; Zhou, Yadi ; Martin, William R. ; Wang, Ruisheng ; Huang, Jin ; Hao, Tong ; Yue, Hong ; Ma, Jing ; Hou, Yuan ; Castrillon, Jessica A. ; Fang, Jiansong ; Lathia, Justin D. ; Keri, Ruth A. ; Lightstone, Felice C. ; Antman, Elliott Marshall ; Rabadan, Raul ; Hill, David E. ; Eng, Charis ; Vidal, Marc ; Loscalzo, Joseph
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-03, Vol.53 (3), p.342-353
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NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations
Author / Creator:Mortimer, Leanne ; Moreau, France ; MacDonald, Justin A ; Chadee, Kris
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2016-10, Vol.17 (10), p.1176-1186
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ATM functions at the peroxisome to induce pexophagy in response to ROS
Author / Creator:Zhang, Jiangwei ; Tripathi, Durga Nand ; Jing, Ji ; Alexander, Angela ; Kim, Jinhee ; Powell, Reid T. ; Dere, Ruhee ; Tait-Mulder, Jacqueline ; Lee, Ji-Hoon ; Paull, Tanya T. ; Pandita, Raj K. ; Charaka, Vijaya K. ; Pandita, Tej K. ; Kastan, Michael B. ; Walker, Cheryl Lyn
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-10, Vol.17 (10), p.1259-1269
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SR Proteins: Binders, Regulators, and Connectors of RNA
Author / Creator:Jeong, Sunjoo
Publisher:Korean Society for Molecular and Cellular Biology
Journal title:Molecules and Cells, 2017, 40(1), , pp.1-9
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ArticlesPeer ReviewedFull Text
Direct stimulation of NADP⁺ synthesis through Akt-mediated phosphorylation of NAD kinase
Author / Creator:Hoxhaj, Gerta ; Ben-Sahra, Issam ; Lockwood, Sophie E. ; Timson, Rebecca C. ; Byles, Vanessa ; Henning, Graham T. ; Gao, Peng ; Selfors, Laura M. ; Asara, John M. ; Manning, Brendan D.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6431), p.1088-1092
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A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution
Author / Creator:Mohammad, Fuad ; Green, Rachel ; Buskirk, Allen R
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2019-02, Vol.8
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A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B
Author / Creator:Pengo, N. ; Agrotis, A. ; Prak, K. ; Jones, J. ; Ketteler, R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-08, Vol.8 (1), p.294-10, Article 294
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cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions
Author / Creator:Sun, Linchong ; Song, Libing ; Wan, Qianfen ; Wu, Gongwei ; Li, Xinghua ; Wang, Yinghui ; Wang, Jin ; Liu, Zhaoji ; Zhong, Xiuying ; He, Xiaoping ; Shen, Shengqi ; Pan, Xin ; Li, Ailing ; Wang, Yulan ; Gao, Ping ; Tang, Huiru ; Zhang, Huafeng
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2015-04, Vol.25 (4), p.429-444
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Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect
Author / Creator:Cheng, Aoxing ; Zhang, Peng ; Wang, Bo ; Yang, Dongdong ; Duan, Xiaotao ; Jiang, Yongliang ; Xu, Tian ; Jiang, Ya ; Shi, Jiahui ; Ding, Chengtao ; Wu, Gao ; Sang, Zhihong ; Wu, Qiang ; Wang, Hua ; Wu, Mian ; Zhang, Zhiyong ; Pan, Xin ; Pan, Yue-yin ; Gao, Ping ; Zhang, Huafeng ; Zhou, Cong-zhao ; Guo, Jing ; Yang, Zhenye
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5566-16, Article 5566
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CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis
Author / Creator:Hanna-Addams, Sarah ; Liu, Shuzhen ; Liu, Hua ; Chen, She ; Wang, Zhigao
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (4), p.1962-1970
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Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression
Author / Creator:Liu, Juan ; Zhang, Cen ; Wu, Hao ; Sun, Xiao-Xin ; Li, Yanchen ; Huang, Shan ; Yue, Xuetian ; Lu, Shou-En ; Shen, Zhiyuan ; Su, Xiaoyang ; White, Eileen ; Haffty, Bruce G ; Hu, Wenwei ; Feng, Zhaohui
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-06, Vol.130 (6), p.3253-3269
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L-serine synthesis via the phosphorylated pathway in humans
Author / Creator:Murtas, Giulia ; Marcone, Giorgia Letizia ; Sacchi, Silvia ; Pollegioni, Loredano
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2020-12, Vol.77 (24), p.5131-5148
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Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics
Author / Creator:Chen, Zhen ; Lei, Caoqi ; Wang, Chao ; Li, Nan ; Srivastava, Mrinal ; Tang, Mengfan ; Zhang, Huimin ; Choi, Jong Min ; Jung, Sung Yun ; Qin, Jun ; Chen, Junjie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.104-104, Article 104
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L-Serine Treatment is Associated with Improvements in Behavior, EEG, and Seizure Frequency in Individuals with GRIN-Related Disorders Due to Null Variants
Author / Creator:Krey, Ilona ; von Spiczak, Sarah ; Johannesen, Kathrine M. ; Hikel, Christiane ; Kurlemann, Gerhard ; Muhle, Hiltrud ; Beysen, Diane ; Dietel, Tobias ; Møller, Rikke S. ; Lemke, Johannes R. ; Syrbe, Steffen
Publisher:Cham: Springer International Publishing
Journal title:Neurotherapeutics, 2022-01, Vol.19 (1), p.334-341
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A swapped genetic code prevents viral infections and gene transfer

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PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress

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Natural Variation Underlies Differences in ETHYLENE RESPONSE FACTOR17 Activity in Fruit Peel Degreening

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LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis

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A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

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Coactivator condensation at super-enhancers links phase separation and gene control

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Comprehensive characterization of protein–protein interactions perturbed by disease mutations

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NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations

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ATM functions at the peroxisome to induce pexophagy in response to ROS

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SR Proteins: Binders, Regulators, and Connectors of RNA

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Direct stimulation of NADP⁺ synthesis through Akt-mediated phosphorylation of NAD kinase

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A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution

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A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B

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cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions

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Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect

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CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis

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Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression

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L-serine synthesis via the phosphorylated pathway in humans

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Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics

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L-Serine Treatment is Associated with Improvements in Behavior, EEG, and Seizure Frequency in Individuals with GRIN-Related Disorders Due to Null Variants

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