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ArticlesPeer ReviewedFull Text
Tripartite Motif 8 (TRIM8) Positively Regulates Pro-inflammatory Responses in Pseudomonas aeruginosa-Induced Keratitis Through Promoting K63-Linked Polyubiquitination of TAK1 Protein
Author / Creator:Guo, Litao ; Dong, Weili ; Fu, Xiaoxiao ; Lin, Jing ; Dong, Zhijun ; Tan, Xiaobo ; Zhang, Tiemin
Publisher:New York: Springer US
Journal title:Inflammation, 2017-04, Vol.40 (2), p.454-463
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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death
Author / Creator:Orning, Pontus ; Weng, Dan ; Starheim, Kristian ; Ratner, Dmitry ; Best, Zachary ; Lee, Bettina ; Brooks, Alexandria ; Xia, Shiyu ; Wu, Hao ; Kelliher, Michelle A ; Berger, Scott B ; Gough, Peter J ; Bertin, John ; Proulx, Megan M ; Goguen, Jon D ; Kayagaki, Nobuhiko ; Fitzgerald, Katherine A ; Lien, Egil
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6418), p.1064-1069
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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
Author / Creator:Sarhan, Joseph ; Liu, Beiyun C. ; Muendlein, Hayley I. ; Li, Peng ; Nilson, Rachael ; Tang, Amy Y. ; Rongvaux, Anthony ; Bunnell, Stephen C. ; Shao, Feng ; Green, Douglas R. ; Poltorak, Alexander
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (46), p.E10888-E10897
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Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke
Author / Creator:Naito, Masanori Gomi ; Xu, Daichao ; Amin, Palak ; Lee, Jinwoo ; Wang, Huibing ; Li, Wanjin ; Kelliher, Michelle ; Pasparakis, Manolis ; Yuan, Junying
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (9), p.4959-4970
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EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma
Author / Creator:Yuan, Li ; Li, Shibing ; Chen, Qiuyan ; Xia, Tianliang ; Luo, Donghua ; Li, Liangji ; Liu, Sailan ; Guo, Shanshan ; Liu, Liting ; Du, Chaochao ; Jia, Guodong ; Li, Xiaoyun ; Lu, Zijian ; Yang, Zhenchong ; Liu, Huanliang ; Mai, Haiqiang ; Tang, Linquan
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2022-08, Vol.29 (8), p.1513-1527
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Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation
Author / Creator:Deng, Yujie ; Lu, Jinqiu ; Li, Wenling ; Wu, Ailing ; Zhang, Xu ; Tong, Wenxue ; Ho, Kiwai Kevin ; Qin, Ling ; Song, Hai ; Mak, Kinglun Kingston
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-11, Vol.9 (1), p.4564-14, Article 4564
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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis
Author / Creator:Geng, Jiefei ; Ito, Yasushi ; Shi, Linyu ; Amin, Palak ; Chu, Jiachen ; Ouchida, Amanda Tomie ; Mookhtiar, Adnan Kasim ; Zhao, Heng ; Xu, Daichao ; Shan, Bing ; Najafov, Ayaz ; Gao, Guangping ; Akira, Shizuo ; Yuan, Junying
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-08, Vol.8 (1), p.359-12, Article 359
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Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
Author / Creator:Dondelinger, Yves ; Delanghe, Tom ; Priem, Dario ; Wynosky-Dolfi, Meghan A. ; Sorobetea, Daniel ; Rojas-Rivera, Diego ; Giansanti, Piero ; Roelandt, Ria ; Gropengiesser, Julia ; Ruckdeschel, Klaus ; Savvides, Savvas N. ; Heck, Albert J. R. ; Vandenabeele, Peter ; Brodsky, Igor E. ; Bertrand, Mathieu J. M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1729-1729, Article 1729
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Multifaceted roles of TAK1 signaling in cancer
Author / Creator:Mukhopadhyay, Himadri ; Lee, Nam Y.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-02, Vol.39 (7), p.1402-1413
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Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma
Author / Creator:Tan, Shuixia ; Zhao, Jing ; Sun, Ziyu ; Cao, Shuangyi ; Niu, Kongyan ; Zhong, Yedan ; Wang, Han ; Shi, Linyu ; Pan, Heling ; Hu, Junhao ; Qian, Lihui ; Liu, Nan ; Yuan, Junying
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (25), p.14231-14242
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Silencing of TGFβ signalling in microglia results in impaired homeostasis
Author / Creator:Zöller, Tanja ; Schneider, Artur ; Kleimeyer, Christian ; Masuda, Takahiro ; Potru, Phani Sankar ; Pfeifer, Dietmar ; Blank, Thomas ; Prinz, Marco ; Spittau, Björn
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4011-13, Article 4011
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FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis
Author / Creator:Wang, Cuicui ; Shen, Jie ; Ying, Jun ; Xiao, Ding ; O’Keefe, Regis J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (48), p.30488-30497
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The long non-coding RNA, SNHG6-003, functions as a competing endogenous RNA to promote the progression of hepatocellular carcinoma
Author / Creator:Cao, C ; Zhang, T ; Zhang, D ; Xie, L ; Zou, X ; Lei, L ; Wu, D ; Liu, L
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-02, Vol.36 (8), p.1112-1122
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The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1
Author / Creator:Zhang, Boyi ; Fu, Da ; Xu, Qixia ; Cong, Xianling ; Wu, Chunyan ; Zhong, Xiaoming ; Ma, Yushui ; Lv, Zhongwei ; Chen, Fei ; Han, Liu ; Qian, Min ; Chin, Y. Eugene ; Lam, Eric W. -F. ; Chiao, Paul ; Sun, Yu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-04, Vol.9 (1), p.1723-19, Article 1723
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Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol
Author / Creator:Yang, Ming ; Qi, Xiaoqiang ; Li, Nan ; Kaifi, Jussuf T. ; Chen, Shiyou ; Wheeler, Andrew A. ; Kimchi, Eric T. ; Ericsson, Aaron C. ; Rector, R. Scott ; Staveley-O’Carroll, Kevin F. ; Li, Guangfu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-01, Vol.14 (1), p.228-228, Article 228
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TGFβ/BMP Signaling Pathway in Cartilage Homeostasis
Author / Creator:Thielen, Nathalie ; van der Kraan, Peter ; van Caam, Arjan
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2019-08, Vol.8 (9), p.969
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TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1
Author / Creator:Zhao, Jian ; Cai, Baoshan ; Shao, Zhugui ; Zhang, Lei ; Zheng, Yi ; Ma, Chunhong ; Yi, Fan ; Liu, Bingyu ; Gao, Chengjiang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2021-11, Vol.28 (11), p.3077-3091
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NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development
Author / Creator:Ratnam, Nivedita M. ; Peterson, Jennifer M. ; Talbert, Erin E. ; Ladner, Katherine J. ; Rajasekera, Priyani V. ; Schmidt, Carl R. ; Dillhoff, Mary E. ; Swanson, Benjamin J. ; Haverick, Ericka ; Kladney, Raleigh D. ; Williams, Terence M. ; Leone, Gustavo W. ; Wang, David J. ; Guttridge, Denis C.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-10, Vol.127 (10), p.3796-3809
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Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization
Author / Creator:Wang, Jinglin ; Liu, Yang ; Ding, Haoran ; Shi, Xiaolei ; Ren, Haozhen
Publisher:London: BioMed Central Ltd
Journal title:Stem cell research & therapy, 2021-01, Vol.12 (1), p.1-15, Article 15
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The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis
Author / Creator:Shu, Bo ; Zhou, Ying-Xia ; Li, Hao ; Zhang, Rui-Zhi ; He, Chao ; Yang, Xin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2021-11, Vol.7 (1), p.368-368, Article 368
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Showing 1 to 20 of 472 results

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Tripartite Motif 8 (TRIM8) Positively Regulates Pro-inflammatory Responses in Pseudomonas aeruginosa-Induced Keratitis Through Promoting K63-Linked Polyubiquitination of TAK1 Protein

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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death

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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection

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Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke

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EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

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Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

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Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

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Multifaceted roles of TAK1 signaling in cancer

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Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma

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Silencing of TGFβ signalling in microglia results in impaired homeostasis

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FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis

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The long non-coding RNA, SNHG6-003, functions as a competing endogenous RNA to promote the progression of hepatocellular carcinoma

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The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

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Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol

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TGFβ/BMP Signaling Pathway in Cartilage Homeostasis

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TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1

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NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

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Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization

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The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis

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