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ArticlesPeer ReviewedFull Text
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
Author / Creator:Li, Bo ; Clohisey, Sara M. ; Chia, Bing Shao ; Wang, Bo ; Cui, Ang ; Eisenhaure, Thomas ; Schweitzer, Lawrence D. ; Hoover, Paul ; Parkinson, Nicholas J. ; Nachshon, Aharon ; Smith, Nikki ; Regan, Tim ; Farr, David ; Gutmann, Michael U. ; Bukhari, Syed Irfan ; Law, Andrew ; Sangesland, Maya ; Gat-Viks, Irit ; Digard, Paul ; Vasudevan, Shobha ; Lingwood, Daniel ; Dockrell, David H. ; Doench, John G. ; Baillie, J. Kenneth ; Hacohen, Nir
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.164-18, Article 164
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Human-to-Human Transmission of Influenza A(H3N2) Virus with Reduced Susceptibility to Baloxavir, Japan, February 2019
Author / Creator:Takashita, Emi ; Ichikawa, Masataka ; Morita, Hiroko ; Ogawa, Rie ; Fujisaki, Seiichiro ; Shirakura, Masayuki ; Miura, Hideka ; Nakamura, Kazuya ; Kishida, Noriko ; Kuwahara, Tomoko ; Sugawara, Hiromi ; Sato, Aya ; Akimoto, Miki ; Mitamura, Keiko ; Abe, Takashi ; Yamazaki, Masahiko ; Watanabe, Shinji ; Hasegawa, Hideki ; Odagiri, Takato
Publisher:United States: U.S. National Center for Infectious Diseases
Journal title:Emerging infectious diseases, 2019-11, Vol.25 (11), p.2108-2111
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Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024
Author / Creator:Takashita, Emi ; Morita, Hiroko ; Nagata, Shiho ; Fujisaki, Seiichiro ; Miura, Hideka ; Ikeda, Tatsuya ; Komabayashi, Kenichi ; Sasaki, Mika ; Matoba, Yohei ; Takahashi, Tomoko ; Ogawa, Naomi ; Mizuta, Katsumi ; Ito, Sueshi ; Kishida, Noriko ; Nakamura, Kazuya ; Shirakura, Masayuki ; Watanabe, Shinji ; Hasegawa, Hideki
Publisher:United States: Centers for Disease Control and Prevention
Journal title:Emerging infectious diseases, 2025-05, Vol.31 (5), p.1019-1022
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Modeling mitigation of influenza epidemics by baloxavir
Author / Creator:Du, Zhanwei ; Nugent, Ciara ; Galvani, Alison P. ; Krug, Robert M. ; Meyers, Lauren Ancel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-06, Vol.11 (1), p.2750-2750, Article 2750
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Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission
Author / Creator:Lee, Leo Yi Yang ; Zhou, Jie ; Frise, Rebecca ; Goldhill, Daniel H. ; Koszalka, Paulina ; Mifsud, Edin J. ; Baba, Kaoru ; Noda, Takahiro ; Ando, Yoshinori ; Sato, Kenji ; Yuki, Aoe-Ishikawa ; Shishido, Takao ; Uehara, Takeki ; Wildum, Steffen ; Zwanziger, Elke ; Collinson, Neil ; Kuhlbusch, Klaus ; Clinch, Barry ; Hurt, Aeron C. ; Barclay, Wendy S.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-04, Vol.16 (4), p.e1008395
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Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets
Author / Creator:Imai, Masaki ; Yamashita, Makoto ; Sakai-Tagawa, Yuko ; Iwatsuki-Horimoto, Kiyoko ; Kiso, Maki ; Murakami, Jurika ; Yasuhara, Atsuhiro ; Takada, Kosuke ; Ito, Mutsumi ; Nakajima, Noriko ; Takahashi, Kenta ; Lopes, Tiago J. S. ; Dutta, Jayeeta ; Khan, Zenab ; Kriti, Divya ; van Bakel, Harm ; Tokita, Akifumi ; Hagiwara, Haruhisa ; Izumida, Naomi ; Kuroki, Haruo ; Nishino, Tamon ; Wada, Noriyuki ; Koga, Michiko ; Adachi, Eisuke ; Jubishi, Daisuke ; Hasegawa, Hideki ; Kawaoka, Yoshihiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2020-01, Vol.5 (1), p.27-33
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Novel modelling approaches to predict the role of antivirals in reducing influenza transmission
Author / Creator:Asher, Jason ; Lemenuel-Diot, Annabelle ; Clay, Matthew ; Durham, David P. ; Mier-y-Teran-Romero, Luis ; Arguello, Carlos J. ; Jolivet, Sebastien ; Wong, Diana Y. ; Kuhlbusch, Klaus ; Clinch, Barry ; Charoin, Jean-Eric
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2023-01, Vol.19 (1), p.e1010797
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The impact of PA/I38 substitutions and PA polymorphisms on the susceptibility of zoonotic influenza A viruses to baloxavir
Author / Creator:Taniguchi, Keiichi ; Noshi, Takeshi ; Omoto, Shinya ; Sato, Akihiko ; Shishido, Takao ; Matsuno, Keita ; Okamatsu, Masatoshi ; Krauss, Scott ; Webby, Richard J ; Sakoda, Yoshihiro ; Kida, Hiroshi
Publisher:Vienna: Springer Vienna
Journal title:Archives of virology, 2024-02, Vol.169 (2), p.29-29, Article 29
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Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil
Author / Creator:Yoshino, Ryunosuke ; Yasuo, Nobuaki ; Sekijima, Masakazu
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-11, Vol.9 (1), p.17464-8, Article 17464
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Baloxavir marboxil, a novel cap-dependent endonuclease inhibitor potently suppresses influenza virus replication and represents therapeutic effects in both immunocompetent and immunocompromised mouse...
Author / Creator:Fukao, Keita ; Ando, Yoshinori ; Noshi, Takeshi ; Kitano, Mitsutaka ; Noda, Takahiro ; Kawai, Makoto ; Yoshida, Ryu ; Sato, Akihiko ; Shishido, Takao ; Naito, Akira
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-05, Vol.14 (5), p.e0217307-e0217307
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Bunyaviral Cap-Snatching Endonuclease Activity and Inhibition with Baloxavir-like Inhibitors in the Context of Full-Length L Proteins
Author / Creator:Loutan, Arlo J. ; Yang, Baiuyan ; Connolly, Gabrielle ; Montoya, Adam ; Smiley, Robert J. ; Chatterjee, Arnab K. ; Götte, Matthias
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2025-03, Vol.17 (3), p.420
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Prophylactic Treatment with Baloxavir Protects Mice from Lethal Infection with Influenza A and B Viruses
Author / Creator:Fukao, Keita ; Noshi, Takeshi ; Shano, Shinya ; Baba, Kaoru ; Sato, Kenji ; Sakuramoto, Masashi ; Kitade, Naohisa ; Tanioka, Hideki ; Kusakabe, Shinji ; Shishido, Takao
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-11, Vol.15 (11), p.2264
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In Vivo Antiviral Activity of Baloxavir against PA/I38T-Substituted Influenza A Viruses at Clinically Relevant Doses
Author / Creator:Kuroda, Takayuki ; Fukao, Keita ; Yoshida, Shinpei ; Oka, Ryoko ; Baba, Kaoru ; Ando, Yoshinori ; Taniguchi, Keiichi ; Noshi, Takeshi ; Shishido, Takao
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-05, Vol.15 (5), p.1154
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Genomic Analysis of Influenza A and B Viruses Carrying Baloxavir Resistance-Associated Substitutions Serially Passaged in Human Epithelial Cells
Author / Creator:Hickerson, Brady T. ; Huang, Bruce K. ; Petrovskaya, Svetlana N. ; Ilyushina, Natalia A.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-12, Vol.15 (12), p.2446
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The Synergistic Effect of Baloxavir and Neuraminidase Inhibitors against Influenza Viruses In Vitro
Author / Creator:Guo, Xiaojia ; Zhao, Lei ; Li, Wei ; Cao, Ruiyuan ; Zhong, Wu
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-09, Vol.16 (9), p.1467
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Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil
Author / Creator:Taniguchi, Keiichi ; Ando, Yoshinori ; Nobori, Haruaki ; Toba, Shinsuke ; Noshi, Takeshi ; Kobayashi, Masanori ; Kawai, Makoto ; Yoshida, Ryu ; Sato, Akihiko ; Shishido, Takao ; Naito, Akira ; Matsuno, Keita ; Okamatsu, Masatoshi ; Sakoda, Yoshihiro ; Kida, Hiroshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-03, Vol.9 (1), p.3466, Article 3466
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Investigating the transmission of baloxavir‐resistant influenza viruses from treated index patients to untreated household contacts in the BLOCKSTONE study
Author / Creator:Harding, Joanne ; Bernasconi, Corrado ; Williams, Sarah ; Wildum, Steffen ; Kinoshita, Masahiro ; Uehara, Takeki ; Hurt, Aeron C.
Publisher:England: John Wiley & Sons, Inc
Journal title:Influenza and other respiratory viruses, 2023-01, Vol.17 (1), p.e13079-n/a
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Virological and Clinical Outcomes of Influenza Outpatients Treated With Baloxavir, Oseltamivir, or Laninamivir in the 2023–2024 Season
Author / Creator:Goto, Takeyuki ; Kawai, Naoki ; Bando, Takuma ; Takasaki, Yoshio ; Shindo, Shizuo ; Sato, Tomonori ; Tani, Naoki ; Chong, Yong ; Ikematsu, Hideyuki
Publisher:England: John Wiley & Sons, Inc
Journal title:Influenza and other respiratory viruses, 2024-11, Vol.18 (11), p.e70042-n/a
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7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors
Author / Creator:Pustenko, Aleksandrs ; Nocentini, Alessio ; Balašova, Anastasija ; Krasavin, Mikhail ; Žalubovskis, Raivis ; Supuran, Claudiu T.
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.650-656
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Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir 1
Author / Creator:Mishin, Vasiliy P ; Patel, Mira C ; Chesnokov, Anton ; De La Cruz, Juan ; Nguyen, Ha T ; Lollis, Lori ; Hodges, Erin ; Jang, Yunho ; Barnes, John ; Uyeki, Timothy ; Davis, Charles T ; Wentworth, David E ; Gubareva, Larisa V
Publisher:United States
Journal title:Emerging infectious diseases, 2019-10, Vol.25 (10), p.1969
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Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

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Human-to-Human Transmission of Influenza A(H3N2) Virus with Reduced Susceptibility to Baloxavir, Japan, February 2019

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Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024

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Modeling mitigation of influenza epidemics by baloxavir

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Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission

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Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets

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Novel modelling approaches to predict the role of antivirals in reducing influenza transmission

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The impact of PA/I38 substitutions and PA polymorphisms on the susceptibility of zoonotic influenza A viruses to baloxavir

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Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil

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Baloxavir marboxil, a novel cap-dependent endonuclease inhibitor potently suppresses influenza virus replication and represents therapeutic effects in both immunocompetent and immunocompromised mouse...

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Bunyaviral Cap-Snatching Endonuclease Activity and Inhibition with Baloxavir-like Inhibitors in the Context of Full-Length L Proteins

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Prophylactic Treatment with Baloxavir Protects Mice from Lethal Infection with Influenza A and B Viruses

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In Vivo Antiviral Activity of Baloxavir against PA/I38T-Substituted Influenza A Viruses at Clinically Relevant Doses

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Genomic Analysis of Influenza A and B Viruses Carrying Baloxavir Resistance-Associated Substitutions Serially Passaged in Human Epithelial Cells

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The Synergistic Effect of Baloxavir and Neuraminidase Inhibitors against Influenza Viruses In Vitro

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Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil

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Investigating the transmission of baloxavir‐resistant influenza viruses from treated index patients to untreated household contacts in the BLOCKSTONE study

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Virological and Clinical Outcomes of Influenza Outpatients Treated With Baloxavir, Oseltamivir, or Laninamivir in the 2023–2024 Season

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7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors

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Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir 1

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