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101 results for Blüthgen,+Nils

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Select record 21
ArticlesPeer ReviewedFull Text
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma
Author / Creator:Schoetz, Ulrike ; Klein, Diana ; Hess, Julia ; Shnayien, Seyd ; Spoerl, Steffen ; Orth, Michael ; Mutlu, Samet ; Hennel, Roman ; Sieber, Anja ; Ganswindt, Ute ; Luka, Benedikt ; Thomsen, Andreas R. ; Unger, Kristian ; Jendrossek, Verena ; Zitzelsberger, Horst ; Blüthgen, Nils ; Belka, Claus ; Unkel, Steffen ; Klinger, Bertram ; Lauber, Kirsten
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-12, Vol.12 (12), p.1162-1162, Article 1162
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Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
Author / Creator:Brandt, Raphael ; Sell, Thomas ; Lüthen, Mareen ; Uhlitz, Florian ; Klinger, Bertram ; Riemer, Pamela ; Giesecke-Thiel, Claudia ; Schulze, Silvia ; El-Shimy, Ismail Amr ; Kunkel, Desiree ; Fauler, Beatrix ; Mielke, Thorsten ; Mages, Norbert ; Herrmann, Bernhard G. ; Sers, Christine ; Blüthgen, Nils ; Morkel, Markus
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.2919-15, Article 2919
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Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo
Author / Creator:Blüthgen, Nils ; van Bentum, Mirjam ; Merz, Barbara ; Kuhl, Dietmar ; Hermey, Guido
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.45101-45101, Article 45101
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Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Author / Creator:Uhlitz, Florian ; Bischoff, Philip ; Peidli, Stefan ; Sieber, Anja ; Trinks, Alexandra ; Lüthen, Mareen ; Obermayer, Benedikt ; Blanc, Eric ; Ruchiy, Yana ; Sell, Thomas ; Mamlouk, Soulafa ; Arsie, Roberto ; Wei, Tzu‐Ting ; Klotz‐Noack, Kathleen ; Schwarz, Roland F ; Sawitzki, Birgit ; Kamphues, Carsten ; Beule, Dieter ; Landthaler, Markus ; Sers, Christine ; Horst, David ; Blüthgen, Nils ; Morkel, Markus
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2021-10, Vol.13 (10), p.e14123-n/a
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Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis
Author / Creator:Aguilar, Carmen ; Pauzuolis, Mindaugas ; Pompaiah, Malvika ; Vafadarnejad, Ehsan ; Arampatzi, Panagiota ; Fischer, Mara ; Narres, Dominik ; Neyazi, Mastura ; Kayisoglu, Özge ; Sell, Thomas ; Blüthgen, Nils ; Morkel, Markus ; Wiegering, Armin ; Germer, Christoph-Thomas ; Kircher, Stefan ; Rosenwald, Andreas ; Saliba, Antoine-Emmanuel ; Bartfeld, Sina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-10, Vol.13 (1), p.5878-5878, Article 5878
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Modeling unveils sex differences of signaling networks in mouse embryonic stem cells
Author / Creator:Sultana, Zeba ; Dorel, Mathurin ; Klinger, Bertram ; Sieber, Anja ; Dunkel, Ilona ; Blüthgen, Nils ; Schulz, Edda G
Publisher:London: EMBO Press
Journal title:Molecular systems biology, 2023-11, Vol.19 (11), p.e11510-e11510
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Select record 27
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Stem Cell‐Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants
Author / Creator:Hoelting, Lisa ; Klima, Stefanie ; Karreman, Christiaan ; Grinberg, Marianna ; Meisig, Johannes ; Henry, Margit ; Rotshteyn, Tamara ; Rahnenführer, Jörg ; Blüthgen, Nils ; Sachinidis, Agapios ; Waldmann, Tanja ; Leist, Marcel
Publisher:Durham, NC, USA: AlphaMed Press
Journal title:Stem cells translational medicine, 2016-04, Vol.5 (4), p.476-487
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Select record 28
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Network quantification of EGFR signaling unveils potential for targeted combination therapy
Author / Creator:Klinger, Bertram ; Sieber, Anja ; Fritsche‐Guenther, Raphaela ; Witzel, Franziska ; Berry, Leanne ; Schumacher, Dirk ; Yan, Yibing ; Durek, Pawel ; Merchant, Mark ; Schäfer, Reinhold ; Sers, Christine ; Blüthgen, Nils
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2013, Vol.9 (1), p.673-n/a
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Select record 29
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Strong negative feedback from Erk to Raf confers robustness to MAPK signalling
Author / Creator:Fritsche‐Guenther, Raphaela ; Witzel, Franziska ; Sieber, Anja ; Herr, Ricarda ; Schmidt, Nadine ; Braun, Sandra ; Brummer, Tilman ; Sers, Christine ; Blüthgen, Nils
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2011-05, Vol.7 (1), p.489-n/a
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Select record 30
ArticlesPeer ReviewedFull Text
An immediate–late gene expression module decodes ERK signal duration
Author / Creator:Uhlitz, Florian ; Sieber, Anja ; Wyler, Emanuel ; Fritsche‐Guenther, Raphaela ; Meisig, Johannes ; Landthaler, Markus ; Klinger, Bertram ; Blüthgen, Nils
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2017-05, Vol.13 (5), p.928-n/a
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Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells
Author / Creator:Berlak, Mareike ; Tucker, Elizabeth ; Dorel, Mathurin ; Winkler, Annika ; McGearey, Aleixandria ; Rodriguez-Fos, Elias ; da Costa, Barbara Martins ; Barker, Karen ; Fyle, Elicia ; Calton, Elizabeth ; Eising, Selma ; Ober, Kim ; Hughes, Deborah ; Koutroumanidou, Eleni ; Carter, Paul ; Stankunaite, Reda ; Proszek, Paula ; Jain, Neha ; Rosswog, Carolina ; Dorado-Garcia, Heathcliff ; Molenaar, Jan Jasper ; Hubank, Mike ; Barone, Giuseppe ; Anderson, John ; Lang, Peter ; Deubzer, Hedwig Elisabeth ; Künkele, Annette ; Fischer, Matthias ; Eggert, Angelika ; Kloft, Charlotte ; Henssen, Anton George ; Boettcher, Michael ; Hertwig, Falk ; Blüthgen, Nils ; Chesler, Louis ; Schulte, Johannes Hubertus
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2022-06, Vol.21 (1), p.126-126, Article 126
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Select record 32
ArticlesPeer ReviewedFull Text
Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients
Author / Creator:Zschaeck, Sebastian ; Klinger, Bertram ; van den Hoff, Jörg ; Cegla, Paulina ; Apostolova, Ivayla ; Kreissl, Michael C. ; Cholewiński, Witold ; Kukuk, Emily ; Strobel, Helen ; Amthauer, Holger ; Blüthgen, Nils ; Zips, Daniel ; Hofheinz, Frank
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-11, Vol.13 (1), p.20840-20840, Article 20840
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Select record 33
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Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance
Author / Creator:Dorel, Mathurin ; Klinger, Bertram ; Mari, Tommaso ; Toedling, Joern ; Blanc, Eric ; Messerschmidt, Clemens ; Nadler-Holly, Michal ; Ziehm, Matthias ; Sieber, Anja ; Hertwig, Falk ; Beule, Dieter ; Eggert, Angelika ; Schulte, Johannes H ; Selbach, Matthias ; Blüthgen, Nils
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2021-11, Vol.17 (11), p.e1009515-e1009515
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Select record 34
ArticlesPeer ReviewedFull Text
Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances
Author / Creator:Dreser, Nadine ; Madjar, Katrin ; Holzer, Anna-Katharina ; Kapitza, Marion ; Scholz, Christopher ; Kranaster, Petra ; Gutbier, Simon ; Klima, Stefanie ; Kolb, David ; Dietz, Christian ; Trefzer, Timo ; Meisig, Johannes ; van Thriel, Christoph ; Henry, Margit ; Berthold, Michael R. ; Blüthgen, Nils ; Sachinidis, Agapios ; Rahnenführer, Jörg ; Hengstler, Jan G. ; Waldmann, Tanja ; Leist, Marcel
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2020-01, Vol.94 (1), p.151-171
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Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data
Author / Creator:Michna, Agata ; Braselmann, Herbert ; Selmansberger, Martin ; Dietz, Anne ; Hess, Julia ; Gomolka, Maria ; Hornhardt, Sabine ; Blüthgen, Nils ; Zitzelsberger, Horst ; Unger, Kristian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-08, Vol.11 (8), p.e0160791-e0160791
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Select record 36
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DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors
Author / Creator:Simon, Tincy ; Riemer, Pamela ; Jarosch, Armin ; Detjen, Katharina ; Di Domenico, Annunziata ; Bormann, Felix ; Menne, Andrea ; Khouja, Slim ; Monjé, Nanna ; Childs, Liam H ; Lenze, Dido ; Leser, Ulf ; Rossner, Florian ; Morkel, Markus ; Blüthgen, Nils ; Pavel, Marianne ; Horst, David ; Capper, David ; Marinoni, Ilaria ; Perren, Aurel ; Mamlouk, Soulafa ; Sers, Christine
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2022-03, Vol.14 (1), p.24-24, Article 24
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Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells
Author / Creator:Jürchott, Karsten ; Kuban, Ralf-Jürgen ; Krech, Till ; Blüthgen, Nils ; Stein, Ulrike ; Walther, Wolfgang ; Friese, Christian ; Kiełbasa, Szymon M ; Ungethüm, Ute ; Lund, Per ; Knösel, Thomas ; Kemmner, Wolfgang ; Morkel, Markus ; Fritzmann, Johannes ; Schlag, Peter M ; Birchmeier, Walter ; Krueger, Tammo ; Sperling, Silke ; Sers, Christine ; Royer, Hans-Dieter ; Herzel, Hanspeter ; Schäfer, Reinhold
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2010-12, Vol.6 (12), p.e1001231
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Select record 38
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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
Author / Creator:Rempel, Eugen ; Hoelting, Lisa ; Waldmann, Tanja ; Balmer, Nina V. ; Schildknecht, Stefan ; Grinberg, Marianna ; Das Gaspar, John Antony ; Shinde, Vaibhav ; Stöber, Regina ; Marchan, Rosemarie ; van Thriel, Christoph ; Liebing, Julia ; Meisig, Johannes ; Blüthgen, Nils ; Sachinidis, Agapios ; Rahnenführer, Jörg ; Hengstler, Jan G. ; Leist, Marcel
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2015-09, Vol.89 (9), p.1599-1618
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Select record 39
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Neuronal activity regulates alternative exon usage
Author / Creator:Denkena, Johanna ; Zaisser, Andrea ; Merz, Barbara ; Klinger, Bertram ; Kuhl, Dietmar ; Blüthgen, Nils ; Hermey, Guido
Publisher:London: BioMed Central Ltd
Journal title:Molecular brain, 2020-11, Vol.13 (1), p.1-148, Article 148
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Select record 40
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Genome-wide profiling of the activity-dependent hippocampal transcriptome
Author / Creator:Hermey, Guido ; Mahlke, Claudia ; Gutzmann, Jakob J ; Schreiber, Jörg ; Blüthgen, Nils ; Kuhl, Dietmar
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e76903-e76903
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Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma

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Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

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Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo

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Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer

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Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis

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Modeling unveils sex differences of signaling networks in mouse embryonic stem cells

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Stem Cell‐Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants

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Network quantification of EGFR signaling unveils potential for targeted combination therapy

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Strong negative feedback from Erk to Raf confers robustness to MAPK signalling

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An immediate–late gene expression module decodes ERK signal duration

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Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells

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Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients

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Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance

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Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances

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Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

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DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors

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Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells

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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

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Neuronal activity regulates alternative exon usage

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Genome-wide profiling of the activity-dependent hippocampal transcriptome

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