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753 results for Cytosine+-+metabolism

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Select record 21
ArticlesPeer ReviewedFull Text
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
Author / Creator:Grünewald, Julian ; Zhou, Ronghao ; Garcia, Sara P. ; Iyer, Sowmya ; Lareau, Caleb A. ; Aryee, Martin J. ; Joung, J. Keith
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-05, Vol.569 (7756), p.433-437
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Base editors for simultaneous introduction of C-to-T and A-to-G mutations
Author / Creator:Sakata, Rina C. ; Ishiguro, Soh ; Mori, Hideto ; Tanaka, Mamoru ; Tatsuno, Kenji ; Ueda, Hiroki ; Yamamoto, Shogo ; Seki, Motoaki ; Masuyama, Nanami ; Nishida, Keiji ; Nishimasu, Hiroshi ; Arakawa, Kazuharu ; Kondo, Akihiko ; Nureki, Osamu ; Tomita, Masaru ; Aburatani, Hiroyuki ; Yachie, Nozomu
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2020-07, Vol.38 (7), p.865-869
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Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing
Author / Creator:Chen, Liang ; Zhu, Biyun ; Ru, Gaomeng ; Meng, Haowei ; Yan, Yongchang ; Hong, Mengjia ; Zhang, Dan ; Luan, Changming ; Zhang, Shun ; Wu, Hao ; Gao, Hongyi ; Bai, Sijia ; Li, Changqing ; Ding, Ruoyi ; Xue, Niannian ; Lei, Zhixin ; Chen, Yuting ; Guan, Yuting ; Siwko, Stefan ; Cheng, Yiyun ; Song, Gaojie ; Wang, Liren ; Yi, Chengqi ; Liu, Mingyao ; Li, Dali
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2023-05, Vol.41 (5), p.663-672
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Global Epigenomic Reconfiguration During Mammalian Brain Development
Author / Creator:Lister, Ryan ; Mukamel, Eran A. ; Nery, Joseph R. ; Urich, Mark ; Puddifoot, Clare A. ; Johnson, Nicholas D. ; Lucero, Jacinta ; Huang, Yun ; Dwork, Andrew J. ; Schultz, Matthew D. ; Yu, Miao ; Tonti-Filippini, Julian ; Heyn, Holger ; Hu, Shijun ; Wu, Joseph C. ; Rao, Anjana ; Esteller, Manel ; He, Chuan ; Haghighi, Fatemeh G. ; Sejnowski, Terrence J. ; Behrens, M. Margarita ; Ecker, Joseph R.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-08, Vol.341 (6146), p.629-629
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Mitochondrial base editor induces substantial nuclear off-target mutations
Author / Creator:Lei, Zhixin ; Meng, Haowei ; Liu, Lulu ; Zhao, Huanan ; Rao, Xichen ; Yan, Yongchang ; Wu, Hao ; Liu, Min ; He, Aibin ; Yi, Chengqi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-06, Vol.606 (7915), p.804-811
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Select record 26
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DNA methylation atlas of the mouse brain at single-cell resolution
Author / Creator:Liu, Hanqing ; Zhou, Jingtian ; Tian, Wei ; Luo, Chongyuan ; Bartlett, Anna ; Aldridge, Andrew ; Lucero, Jacinta ; Osteen, Julia K. ; Nery, Joseph R. ; Chen, Huaming ; Rivkin, Angeline ; Castanon, Rosa G. ; Clock, Ben ; Li, Yang Eric ; Hou, Xiaomeng ; Poirion, Olivier B. ; Preissl, Sebastian ; Pinto-Duarte, Antonio ; O’Connor, Carolyn ; Boggeman, Lara ; Fitzpatrick, Conor ; Nunn, Michael ; Mukamel, Eran A. ; Zhang, Zhuzhu ; Callaway, Edward M. ; Ren, Bing ; Dixon, Jesse R. ; Behrens, M. Margarita ; Ecker, Joseph R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-10, Vol.598 (7879), p.120-128
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Select record 27
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Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing
Author / Creator:Yuen, Zaka Wing-Sze ; Srivastava, Akanksha ; Daniel, Runa ; McNevin, Dennis ; Jack, Cameron ; Eyras, Eduardo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3438-3438, Article 3438
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Select record 28
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Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Author / Creator:Yu, Yi ; Leete, Thomas C. ; Born, David A. ; Young, Lauren ; Barrera, Luis A. ; Lee, Seung-Joo ; Rees, Holly A. ; Ciaramella, Giuseppe ; Gaudelli, Nicole M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-04, Vol.11 (1), p.2052-10, Article 2052
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Select record 29
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Active turnover of DNA methylation during cell fate decisions
Author / Creator:Parry, Aled ; Rulands, Steffen ; Reik, Wolf
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2021-01, Vol.22 (1), p.59-66
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Select record 30
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rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome
Author / Creator:Kwok, Chun Kit ; Marsico, Giovanni ; Sahakyan, Aleksandr B ; Chambers, Vicki S ; Balasubramanian, Shankar
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2016-10, Vol.13 (10), p.841-844
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Select record 31
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The landscape of cancer genes and mutational processes in breast cancer
Author / Creator:Stephens, Philip J. ; Tarpey, Patrick S. ; Davies, Helen ; Van Loo, Peter ; Greenman, Chris ; Wedge, David C. ; Nik-Zainal, Serena ; Martin, Sancha ; Varela, Ignacio ; Bignell, Graham R. ; Yates, Lucy R. ; Papaemmanuil, Elli ; Beare, David ; Butler, Adam ; Cheverton, Angela ; Gamble, John ; Hinton, Jonathan ; Jia, Mingming ; Jayakumar, Alagu ; Jones, David ; Latimer, Calli ; Lau, King Wai ; McLaren, Stuart ; McBride, David J. ; Menzies, Andrew ; Mudie, Laura ; Raine, Keiran ; Rad, Roland ; Spencer Chapman, Michael ; Teague, Jon ; Easton, Douglas ; Langerød, Anita ; Lee, Ming Ta Michael ; Shen, Chen-Yang ; Tee, Benita Tan Kiat ; Huimin, Bernice Wong ; Broeks, Annegien ; Vargas, Ana Cristina ; Turashvili, Gulisa ; Martens, John ; Fatima, Aquila ; Miron, Penelope ; Chin, Suet-Feung ; Thomas, Gilles ; Boyault, Sandrine ; Mariani, Odette ; Lakhani, Sunil R. ; van de Vijver, Marc ; van ‘t Veer, Laura ; Foekens, John ; Desmedt, Christine ; Sotiriou, Christos ; Tutt, Andrew ; Caldas, Carlos ; Reis-Filho, Jorge S. ; Aparicio, Samuel A. J. R. ; Salomon, Anne Vincent ; Børresen-Dale, Anne-Lise ; Richardson, Andrea L. ; Campbell, Peter J. ; Futreal, P. Andrew ; Stratton, Michael R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-05, Vol.486 (7403), p.400-404
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Select record 32
ArticlesPeer ReviewedFull Text
Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability
Author / Creator:Ngo, Thuy T. M. ; Yoo, Jejoong ; Dai, Qing ; Zhang, Qiucen ; He, Chuan ; Aksimentiev, Aleksei ; Ha, Taekjip
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-02, Vol.7 (1), p.10813-10813, Article 10813
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Select record 33
ArticlesPeer ReviewedFull Text
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
Author / Creator:Blaschke, Kathryn ; Ebata, Kevin T. ; Karimi, Mohammad M. ; Zepeda-Martínez, Jorge A. ; Goyal, Preeti ; Mahapatra, Sahasransu ; Tam, Angela ; Laird, Diana J. ; Hirst, Martin ; Rao, Anjana ; Lorincz, Matthew C. ; Ramalho-Santos, Miguel
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-08, Vol.500 (7461), p.222-226
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Select record 34
ArticlesPeer ReviewedFull Text
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
Author / Creator:Ito, Shinsuke ; Shen, Li ; Dai, Qing ; Wu, Susan C. ; Collins, Leonard B. ; Swenberg, James A. ; He, Chuan ; Zhang, Yi
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6047), p.1300-1303
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Select record 35
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A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects
Author / Creator:Zuo, Erwei ; Sun, Yidi ; Yuan, Tanglong ; He, Bingbing ; Zhou, Changyang ; Ying, Wenqin ; Liu, Jing ; Wei, Wu ; Zeng, Rong ; Li, Yixue ; Yang, Hui
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2020-06, Vol.17 (6), p.600-604
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Select record 36
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Stem cell function and stress response are controlled by protein synthesis
Author / Creator:Blanco, Sandra ; Bandiera, Roberto ; Popis, Martyna ; Hussain, Shobbir ; Lombard, Patrick ; Aleksic, Jelena ; Sajini, Abdulrahim ; Tanna, Hinal ; Cortés-Garrido, Rosana ; Gkatza, Nikoletta ; Dietmann, Sabine ; Frye, Michaela
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-06, Vol.534 (7607), p.335-340
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Select record 37
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Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine
Author / Creator:Hackett, Jamie A. ; Sengupta, Roopsha ; Zylicz, Jan J. ; Murakami, Kazuhiro ; Lee, Caroline ; Down, Thomas A. ; Surani, M. Azim
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-01, Vol.339 (6118), p.448-452
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Select record 38
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Precision mitochondrial DNA editing with high-fidelity DddA-derived base editors
Author / Creator:Lee, Seonghyun ; Lee, Hyunji ; Baek, Gayoung ; Kim, Jin-Soo
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2023-03, Vol.41 (3), p.378-386
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Select record 39
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Genome-wide detection of cytosine methylations in plant from Nanopore data using deep learning
Author / Creator:Ni, Peng ; Huang, Neng ; Nie, Fan ; Zhang, Jun ; Zhang, Zhi ; Wu, Bo ; Bai, Lu ; Liu, Wende ; Xiao, Chuan-Le ; Luo, Feng ; Wang, Jianxin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.5976-11, Article 5976
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Select record 40
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DNA-binding factors shape the mouse methylome at distal regulatory regions
Author / Creator:Stadler, Michael B. ; Murr, Rabih ; Burger, Lukas ; Ivanek, Robert ; Lienert, Florian ; Schöler, Anne ; Nimwegen, Erik van ; Wirbelauer, Christiane ; Oakeley, Edward J. ; Gaidatzis, Dimos ; Tiwari, Vijay K. ; Schübeler, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-12, Vol.480 (7378), p.490-495
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Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

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Base editors for simultaneous introduction of C-to-T and A-to-G mutations

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Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

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Global Epigenomic Reconfiguration During Mammalian Brain Development

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Mitochondrial base editor induces substantial nuclear off-target mutations

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DNA methylation atlas of the mouse brain at single-cell resolution

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Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing

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Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

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Active turnover of DNA methylation during cell fate decisions

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rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome

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The landscape of cancer genes and mutational processes in breast cancer

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Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability

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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

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Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

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A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

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Stem cell function and stress response are controlled by protein synthesis

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Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine

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Precision mitochondrial DNA editing with high-fidelity DddA-derived base editors

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Genome-wide detection of cytosine methylations in plant from Nanopore data using deep learning

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DNA-binding factors shape the mouse methylome at distal regulatory regions

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