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ArticlesPeer ReviewedFull Text
Crystal structure of the human σ1 receptor
Author / Creator:Schmidt, Hayden R. ; Zheng, Sanduo ; Gurpinar, Esin ; Koehl, Antoine ; Manglik, Aashish ; Kruse, Andrew C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-04, Vol.532 (7600), p.527-530
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Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator
Author / Creator:Wu, Huixian ; Wang, Chong ; Gregory, Karen J. ; Han, Gye Won ; Cho, Hyekyung P. ; Xia, Yan ; Niswender, Colleen M. ; Katritch, Vsevolod ; Meiler, Jens ; Cherezov, Vadim ; Conn, P. Jeffrey ; Stevens, Raymond C.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-04, Vol.344 (6179), p.58-64
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Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
Author / Creator:Song, Gaojie ; Yang, Dehua ; Wang, Yuxia ; de Graaf, Chris ; Zhou, Qingtong ; Jiang, Shanshan ; Liu, Kaiwen ; Cai, Xiaoqing ; Dai, Antao ; Lin, Guangyao ; Liu, Dongsheng ; Wu, Fan ; Wu, Yiran ; Zhao, Suwen ; Ye, Li ; Han, Gye Won ; Lau, Jesper ; Wu, Beili ; Hanson, Michael A. ; Liu, Zhi-Jie ; Wang, Ming-Wei ; Stevens, Raymond C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-06, Vol.546 (7657), p.312-315
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Molecular basis for ligand activation of the human KCNQ2 channel
Author / Creator:Li, Xiaoxiao ; Zhang, Qiansen ; Guo, Peipei ; Fu, Jie ; Mei, Lianghe ; Lv, Dashuai ; Wang, Jiangqin ; Lai, Dongwu ; Ye, Sheng ; Yang, Huaiyu ; Guo, Jiangtao
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2021-01, Vol.31 (1), p.52-61
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Structure of the full-length glucagon class B G-protein-coupled receptor
Author / Creator:Zhang, Haonan ; Qiao, Anna ; Yang, Dehua ; Yang, Linlin ; Dai, Antao ; de Graaf, Chris ; Reedtz-Runge, Steffen ; Dharmarajan, Venkatasubramanian ; Zhang, Hui ; Han, Gye Won ; Grant, Thomas D. ; Sierra, Raymond G. ; Weierstall, Uwe ; Nelson, Garrett ; Liu, Wei ; Wu, Yanhong ; Ma, Limin ; Cai, Xiaoqing ; Lin, Guangyao ; Wu, Xiaoai ; Geng, Zhi ; Dong, Yuhui ; Song, Gaojie ; Griffin, Patrick R. ; Lau, Jesper ; Cherezov, Vadim ; Yang, Huaiyu ; Hanson, Michael A. ; Stevens, Raymond C. ; Zhao, Qiang ; Jiang, Hualiang ; Wang, Ming-Wei ; Wu, Beili
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-06, Vol.546 (7657), p.259-264
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ZEB1‐associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat
Author / Creator:Meidhof, Simone ; Brabletz, Simone ; Lehmann, Waltraut ; Preca, Bogdan‐Tiberius ; Mock, Kerstin ; Ruh, Manuel ; Schüler, Julia ; Berthold, Maria ; Weber, Anika ; Burk, Ulrike ; Lübbert, Michael ; Puhr, Martin ; Culig, Zoran ; Wellner, Ulrich ; Keck, Tobias ; Bronsert, Peter ; Küsters, Simon ; Hopt, Ulrich T ; Stemmler, Marc P ; Brabletz, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2015-06, Vol.7 (6), p.831-847
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ArticlesPeer ReviewedFull Text
Dopaminergic Network Differences in Human Impulsivity
Author / Creator:Buckholtz, Joshua W ; Treadway, Michael T ; Cowan, Ronald L ; Woodward, Neil D ; Li, Rui ; Ansari, M. Sib ; Baldwin, Ronald M ; Schwartzman, Ashley N ; Shelby, Evan S ; Smith, Clarence E ; Kessler, Robert M ; Zald, David H
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5991), p.532-532
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ArticlesPeer ReviewedFull Text
Sequential induction of Fur-regulated genes in response to iron limitation in Bacillus subtilis
Author / Creator:Pi, Hualiang ; Helmann, John D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (48), p.12785-12790
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A molecular switch regulating transcriptional repression and activation of PPARγ
Author / Creator:Shang, Jinsai ; Mosure, Sarah A. ; Zheng, Jie ; Brust, Richard ; Bass, Jared ; Nichols, Ashley ; Solt, Laura A. ; Griffin, Patrick R. ; Kojetin, Douglas J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.956-956, Article 956
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ArticlesPeer ReviewedFull Text
Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2
Author / Creator:Forrester, Alison ; Rathjen, Stefan J. ; Daniela Garcia-Castillo, Maria ; Bachert, Collin ; Couhert, Audrey ; Tepshi, Livia ; Pichard, Sylvain ; Martinez, Jennifer ; Munier, Mathilde ; Sierocki, Raphael ; Renard, Henri-François ; Augusto Valades-Cruz, César ; Dingli, Florent ; Loew, Damarys ; Lamaze, Christophe ; Cintrat, Jean-Christophe ; Linstedt, Adam D. ; Gillet, Daniel ; Barbier, Julien ; Johannes, Ludger
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2020-03, Vol.16 (3), p.327-336
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ArticlesPeer ReviewedFull Text
Controlling protein activity by dynamic recruitment on a supramolecular polymer platform
Author / Creator:Wijnands, Sjors P. W. ; Engelen, Wouter ; Lafleur, René P. M. ; Meijer, E. W. ; Merkx, Maarten
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.65-9, Article 65
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ArticlesPeer ReviewedFull Text
Nucleus Accumbens D2/3 Receptors Predict Trait Impulsivity and Cocaine Reinforcement
Author / Creator:Dalley, Jeffrey W. ; Fryer, Tim D. ; Brichard, Laurent ; Robinson, Emma S. J. ; Theobald, David E. H. ; Lääne, Kristjan ; Peña, Yolanda ; Murphy, Emily R. ; Shah, Yasmene ; Probst, Katrin ; Abakumova, Irina ; Aigbirhio, Franklin I. ; Richards, Hugh K. ; Hong, Young ; Baron, Jean-Claude ; Everitt, Barry J. ; Robbins, Trevor W.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2007-03, Vol.315 (5816), p.1267-1270
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ArticlesPeer ReviewedFull Text
PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age
Author / Creator:Vijay, Aishwarya ; Cavallo, Dana ; Goldberg, Alissa ; de Laat, Bart ; Nabulsi, Nabeel ; Huang, Yiyun ; Krishnan-Sarin, Suchitra ; Morris, Evan D
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2018-12, Vol.43 (13), p.2539-2547
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ArticlesPeer ReviewedFull Text
Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Author / Creator:Awakawa, Takayoshi ; Fujioka, Takuma ; Zhang, Lihan ; Hoshino, Shotaro ; Hu, Zhijuan ; Hashimoto, Junko ; Kozone, Ikuko ; Ikeda, Haruo ; Shin-Ya, Kazuo ; Liu, Wen ; Abe, Ikuro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3534-10, Article 3534
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Upregulation of CD22 by Chidamide promotes CAR T cells functionality
Author / Creator:Yang, Xin ; Yu, Qiuxia ; Xu, Hao ; Zhou, Jianfeng
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-10, Vol.11 (1), p.20637-20637, Article 20637
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ArticlesPeer ReviewedFull Text
NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors
Author / Creator:Skora, Lukasz ; Mestan, Jürgen ; Fabbro, Doriano ; Jahnke, Wolfgang ; Grzesiek, Stephan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.E4437-E4445
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ArticlesPeer ReviewedFull Text
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain
Author / Creator:James, Lindsey I ; Barsyte-Lovejoy, Dalia ; Zhong, Nan ; Krichevsky, Liubov ; Korboukh, Victoria K ; Herold, J Martin ; MacNevin, Christopher J ; Norris, Jacqueline L ; Sagum, Cari A ; Tempel, Wolfram ; Marcon, Edyta ; Guo, Hongbo ; Gao, Cen ; Huang, Xi-Ping ; Duan, Shili ; Emili, Andrew ; Greenblatt, Jack F ; Kireev, Dmitri B ; Jin, Jian ; Janzen, William P ; Brown, Peter J ; Bedford, Mark T ; Arrowsmith, Cheryl H ; Frye, Stephen V
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2013-03, Vol.9 (3), p.184-191
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ArticlesPeer ReviewedFull Text
Chemical and Genetic Engineering of Selective Ion Channel—Ligand Interactions
Author / Creator:Magnus, Christopher J. ; Lee, Peter H. ; Atasoy, Deniz ; Su, Helen H. ; Looger, Loren L. ; Sternson, Scott M.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6047), p.1292-1296
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Lower [ 18 F]fallypride binding to dopamine D 2/3 receptors in frontal brain areas in adults with 22q11.2 deletion syndrome: a positron emission tomography study
Author / Creator:van Duin, Esther D A ; Ceccarini, Jenny ; Booij, Jan ; Kasanova, Zuzana ; Vingerhoets, Claudia ; van Huijstee, Jytte ; Heinzel, Alexander ; Mohammadkhani-Shali, Siamak ; Winz, Oliver ; Mottaghy, Felix ; Myin-Germeys, Inez ; van Amelsvoort, Thérèse
Publisher:England
Journal title:Psychological medicine, 2020-04, Vol.50 (5), p.799-807
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Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury
Author / Creator:Sada, Naoki ; Fujita, Yuki ; Mizuta, Nanano ; Ueno, Masaki ; Furukawa, Takahisa ; Yamashita, Toshihide
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-08, Vol.11 (8), p.655-655, Article 655
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Crystal structure of the human σ1 receptor

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Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

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Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

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Molecular basis for ligand activation of the human KCNQ2 channel

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Structure of the full-length glucagon class B G-protein-coupled receptor

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ZEB1‐associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat

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Dopaminergic Network Differences in Human Impulsivity

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Sequential induction of Fur-regulated genes in response to iron limitation in Bacillus subtilis

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A molecular switch regulating transcriptional repression and activation of PPARγ

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Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2

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Controlling protein activity by dynamic recruitment on a supramolecular polymer platform

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Nucleus Accumbens D2/3 Receptors Predict Trait Impulsivity and Cocaine Reinforcement

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PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age

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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

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Upregulation of CD22 by Chidamide promotes CAR T cells functionality

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NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors

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Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

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Chemical and Genetic Engineering of Selective Ion Channel—Ligand Interactions

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Lower [ 18 F]fallypride binding to dopamine D 2/3 receptors in frontal brain areas in adults with 22q11.2 deletion syndrome: a positron emission tomography study

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Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury

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