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796 results for Calcineurin+-+metabolism

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Neuronal regulation of type 2 innate lymphoid cells via neuromedin U
Author / Creator:Cardoso, Vânia ; Chesné, Julie ; Ribeiro, Hélder Manuel ; García Cassani, Bethania ; Carvalho, Tânia ; Bouchery, Tiffany ; Shah, Kathleen ; BARBOSA MORAIS, NUNO LUÍS ; Harris, Nicola ; Veiga-Fernandes, Henrique
Publisher:London: Springer Nature
Journal title:Nature (London), 2017-09, Vol.549 (7671), p.277-281
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Gsmtx4 Alleviated Osteoarthritis through Piezo1/Calcineurin/NFAT1 Signaling Axis under Excessive Mechanical Strain
Author / Creator:Ren, Xunshan ; Zhuang, Huangming ; Li, Bin ; Jiang, Fuze ; Zhang, Yuelong ; Zhou, Panghu
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-02, Vol.24 (4), p.4022
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TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
Author / Creator:Khan, Omar ; Giles, Josephine R. ; McDonald, Sierra ; Manne, Sasikanth ; Ngiow, Shin Foong ; Patel, Kunal P. ; Werner, Michael T. ; Huang, Alexander C. ; Alexander, Katherine A. ; Wu, Jennifer E. ; Attanasio, John ; Yan, Patrick ; George, Sangeeth M. ; Bengsch, Bertram ; Staupe, Ryan P. ; Donahue, Greg ; Xu, Wei ; Amaravadi, Ravi K. ; Xu, Xiaowei ; Karakousis, Giorgos C. ; Mitchell, Tara C. ; Schuchter, Lynn M. ; Kaye, Jonathan ; Berger, Shelley L. ; Wherry, E. John
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7764), p.211-218
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Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
Author / Creator:Medina, Diego L. ; Di Paola, Simone ; Peluso, Ivana ; Armani, Andrea ; De Stefani, Diego ; Venditti, Rossella ; Montefusco, Sandro ; Scotto-Rosato, Anna ; Prezioso, Carolina ; Forrester, Alison ; Settembre, Carmine ; Wang, Wuyang ; Gao, Qiong ; Xu, Haoxing ; Sandri, Marco ; Rizzuto, Rosario ; De Matteis, Maria Antonietta ; Ballabio, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-03, Vol.17 (3), p.288-299
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Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
Author / Creator:Blanchard, Joel W. ; Bula, Michael ; Davila-Velderrain, Jose ; Akay, Leyla Anne ; Zhu, Lena ; Frank, Alexander ; Victor, Matheus B. ; Bonner, Julia Maeve ; Mathys, Hansruedi ; Lin, Yuan-Ta ; Ko, Tak ; Bennett, David A. ; Cam, Hugh P. ; Kellis, Manolis ; Tsai, Li-Huei
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-06, Vol.26 (6), p.952-963
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A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes
Author / Creator:Nguyen, Ngoc Uyen Nhi ; Canseco, Diana C. ; Xiao, Feng ; Nakada, Yuji ; Li, Shujuan ; Lam, Nicholas T. ; Muralidhar, Shalini A. ; Savla, Jainy J. ; Hill, Joseph A. ; Le, Victor ; Zidan, Kareem A. ; El-Feky, Hamed W. ; Wang, Zhaoning ; Ahmed, Mahmoud Salama ; Hubbi, Maimon E. ; Menendez-Montes, Ivan ; Moon, Jesung ; Ali, Shah R. ; Le, Victoria ; Villalobos, Elisa ; Mohamed, Magid S. ; Elhelaly, Waleed M. ; Thet, Suwannee ; Anene-Nzelu, Chukwuemeka George ; Tan, Wilson Lek Wen ; Foo, Roger S. ; Meng, Xun ; Kanchwala, Mohammed ; Xing, Chao ; Roy, Jagoree ; Cyert, Martha S. ; Rothermel, Beverly A. ; Sadek, Hesham A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-06, Vol.582 (7811), p.271-276
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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
Author / Creator:Cereghetti, G.M ; Stangherlin, A ; de Brito, O. Martins ; Chang, C.R ; Blackstone, C ; Bernardi, P ; Scorrano, L
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (41), p.15803-15808
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Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling
Author / Creator:Kasahara, Atsuko ; Cipolat, Sara ; Chen, Yun ; Dorn, Gerald W. ; Scorrano, Luca
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6159), p.734-737
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Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
Author / Creator:Kumar, Suresh ; Jain, Ashish ; Choi, Seong Won ; da Silva, Gustavo Peixoto Duarte ; Allers, Lee ; Mudd, Michal H. ; Peters, Ryan Scott ; Anonsen, Jan Haug ; Rusten, Tor-Erik ; Lazarou, Michael ; Deretic, Vojo
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-08, Vol.22 (8), p.973-985
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Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling
Author / Creator:Dai, Chunhua ; Hang, Yan ; Shostak, Alena ; Poffenberger, Greg ; Hart, Nathaniel ; Prasad, Nripesh ; Phillips, Neil ; Levy, Shawn E. ; Greiner, Dale L. ; Shultz, Leonard D. ; Bottino, Rita ; Kim, Seung K. ; Powers, Alvin C.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-10, Vol.127 (10), p.3835-3844
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Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling
Author / Creator:Yin, Yaling ; Gao, Di ; Wang, Yali ; Wang, Zhi-Hao ; Wang, Xin ; Ye, Jinwang ; Wu, Dongqin ; Fang, Lin ; Pi, Guilin ; Yang, Ying ; Wang, Xiao-Chuan ; Lu, Chengbiao ; Ye, Keqiang ; Wang, Jian-Zhi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (26), p.E3773-E3781
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SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice
Author / Creator:Miyata, Haruhiko ; Oura, Seiya ; Morohoshi, Akane ; Shimada, Keisuke ; Mashiko, Daisuke ; Oyama, Yuki ; Kaneda, Yuki ; Matsumura, Takafumi ; Abbasi, Ferheen ; Ikawa, Masahito
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (35), p.1-9
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Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface
Author / Creator:Shigdel, Uddhav K. ; Lee, Seung-Joo ; Sowa, Mathew E. ; Bowman, Brian R. ; Robison, Keith ; Zhou, Minyun ; Pua, Khian Hong ; Stiles, Dylan T. ; Blodgett, Joshua A. V. ; Udwary, Daniel W. ; Rajczewski, Andrew T. ; Mann, Alan S. ; Mostafavi, Siavash ; Hardy, Tara ; Arya, Sukrat ; Weng, Zhigang ; Stewart, Michelle ; Kenyon, Kyle ; Morgenstern, Jay P. ; Pan, Ende ; Gray, Daniel C. ; Pollock, Roy M. ; Fry, Andrew M. ; Klausner, Richard D. ; Townson, Sharon A. ; Verdine, Gregory L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (29), p.17195-17203
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Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region
Author / Creator:Lee, Sun-Kyung ; Ahnn, Joohong
Publisher:Korean Society for Molecular and Cellular Biology
Journal title:Molecules and Cells, 2020, 43(8), , pp.671-685
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Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer
Author / Creator:Luo, Liyun ; Zhang, Zhijie ; Qiu, Ni ; Ling, Li ; Jia, Xiaoting ; Song, Ying ; Li, Hongsheng ; Li, Jiansheng ; Lyu, Hui ; Liu, Hao ; He, Zhimin ; Liu, Bolin ; Zheng, Guopei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.2699-2699, Article 2699
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Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
Author / Creator:D'Amelio, Marcello ; Cavallucci, Virve ; Middei, Silvia ; Marchetti, Cristina ; Pacioni, Simone ; Ferri, Alberto ; Diamantini, Adamo ; De Zio, Daniela ; Carrara, Paolo ; Battistini, Luca ; Moreno, Sandra ; Bacci, Alberto ; Ammassari-Teule, Martine ; Marie, Hélène ; Cecconi, Francesco
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2011-01, Vol.14 (1), p.69-76
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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents
Author / Creator:Juvvadi, Praveen R. ; Fox, David ; Bobay, Benjamin G. ; Hoy, Michael J. ; Gobeil, Sophie M. C. ; Venters, Ronald A. ; Chang, Zanetta ; Lin, Jackie J. ; Averette, Anna Floyd ; Cole, D. Christopher ; Barrington, Blake C. ; Wheaton, Joshua D. ; Ciofani, Maria ; Trzoss, Michael ; Li, Xiaoming ; Lee, Soo Chan ; Chen, Ying-Lien ; Mutz, Mitchell ; Spicer, Leonard D. ; Schumacher, Maria A. ; Heitman, Joseph ; Steinbach, William J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4275-18, Article 4275
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Calcineurin promotes adaptation to chronic stress through two distinct mechanisms
Author / Creator:Flynn, Mackenzie J. ; Harper, Nicholas W. ; Li, Rui ; Zhu, Lihua Julie ; Lee, Michael J. ; Benanti, Jennifer A.
Publisher:United States: American Society for Cell Biology
Journal title:Molecular biology of the cell, 2024-10, Vol.35 (10), p.ar123
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Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity
Author / Creator:Zhitomirsky, Benny ; Yunaev, Anna ; Kreiserman, Roman ; Kaplan, Ariel ; Stark, Michal ; Assaraf, Yehuda G.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-12, Vol.9 (12), p.1191-15, Article 1191
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3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury
Author / Creator:Zhang, Haojie ; Ni, Wenfei ; Yu, Gaoxiang ; Geng, Yibo ; Lou, Junsheng ; Qi, Jianjun ; Chen, Yituo ; Li, Feida ; Ye, Hantao ; Ma, Haiwei ; Xu, Hui ; Zhao, Luying ; Cai, Yuepiao ; Wang, Xiangyang ; Xu, Huazi ; Xiao, Jian ; Zhou, Kailiang
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2023, Vol.13 (2), p.810-832
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Neuronal regulation of type 2 innate lymphoid cells via neuromedin U

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Gsmtx4 Alleviated Osteoarthritis through Piezo1/Calcineurin/NFAT1 Signaling Axis under Excessive Mechanical Strain

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TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

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Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

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Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

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A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes

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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

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Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling

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Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

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Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling

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Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling

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SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice

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Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface

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Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region

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Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer

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Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents

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Calcineurin promotes adaptation to chronic stress through two distinct mechanisms

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Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity

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3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury

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