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ArticlesPeer ReviewedFull Text
Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A
Author / Creator:Gupta, Anurag Kumar ; Giaglis, Stavros ; Hasler, Paul ; Hahn, Sinuhe
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-05, Vol.9 (5), p.e97088-e97088
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Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter
Author / Creator:Elefantova, Katarina ; Lakatos, Boris ; Kubickova, Jana ; Sulova, Zdena ; Breier, Albert
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-07, Vol.19 (7), p.1985
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Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase
Author / Creator:He, Jiuya ; Carroll, Joe ; Ding, Shujing ; Fearnley, Ian M. ; Walker, John E.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (34), p.9086-9091
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ArticlesPeer ReviewedFull Text
Voclosporin: First Approval: Voclosporin: First Approval
Author / Creator:Heo, Young-A
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2021-04, Vol.81 (5), p.605-610
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Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways
Author / Creator:Kirkby, Nicholas S. ; Chan, Melissa V. ; Zaiss, Anne K. ; Garcia-Vaz, Eliana ; Jiao, Jing ; Berglund, Lisa M. ; Verdu, Elena F. ; Ahmetaj-Shala, Blerina ; Wallace, John L. ; Herschman, Harvey R. ; Gomez, Maria F. ; Mitchell, Jane A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (2), p.434-439
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ArticlesPeer ReviewedFull Text
Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive
Author / Creator:Miyata, Haruhiko ; Satouh, Yuhkoh ; Mashiko, Daisuke ; Muto, Masanaga ; Nozawa, Kaori ; Shiba, Kogiku ; Fujihara, Yoshitaka ; Isotani, Ayako ; Inaba, Kazuo ; Ikawa, Masahito
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-10, Vol.350 (6259), p.442-445
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The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors
Author / Creator:Pfefferle, Susanne ; Schöpf, Julia ; Kögl, Manfred ; Friedel, Caroline C. ; Müller, Marcel A. ; Carbajo-Lozoya, Javier ; Stellberger, Thorsten ; von Dall’Armi, Ekatarina ; Herzog, Petra ; Kallies, Stefan ; Niemeyer, Daniela ; Ditt, Vanessa ; Kuri, Thomas ; Züst, Roland ; Pumpor, Ksenia ; Hilgenfeld, Rolf ; Schwarz, Frank ; Zimmer, Ralf ; Steffen, Imke ; Weber, Friedemann ; Thiel, Volker ; Herrler, Georg ; Thiel, Heinz-Jürgen ; Schwegmann-Weßels, Christel ; Pöhlmann, Stefan ; Haas, Jürgen ; Drosten, Christian ; von Brunn, Albrecht
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2011-10, Vol.7 (10), p.e1002331
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ArticlesPeer ReviewedFull Text
Screening of tau protein kinase inhibitors in a tauopathy-relevant cell-based model of tau hyperphosphorylation and oligomerization
Author / Creator:Yadikar, Hamad ; Torres, Isabel ; Aiello, Gabrielle ; Kurup, Milin ; Yang, Zhihui ; Lin, Fan ; Kobeissy, Firas ; Yost, Richard ; Wang, Kevin K.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-07, Vol.15 (7), p.e0224952
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ArticlesPeer ReviewedFull Text
CaMKII determines mitochondrial stress responses in heart
Author / Creator:Joiner, Mei-ling A. ; Koval, Olha M. ; Li, Jingdong ; He, B. Julie ; Allamargot, Chantal ; Gao, Zhan ; Luczak, Elizabeth D. ; Hall, Duane D. ; Fink, Brian D. ; Chen, Biyi ; Yang, Jinying ; Moore, Steven A. ; Scholz, Thomas D. ; Strack, Stefan ; Mohler, Peter J. ; Sivitz, William I. ; Song, Long-Sheng ; Anderson, Mark E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-11, Vol.491 (7423), p.269-273
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ArticlesPeer ReviewedFull Text
Cyclosporine A-resistant CAR-T cells mediate antitumour immunity in the presence of allogeneic cells
Author / Creator:Zhang, Yixi ; Fang, Hongyu ; Wang, Guocan ; Yuan, Guangxun ; Dong, Ruoyu ; Luo, Jijun ; Lyu, Yu ; Wang, Yajie ; Li, Peng ; Zhou, Chun ; Yin, Weiwei ; Xiao, Haowen ; Sun, Jie ; Zeng, Xun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-12, Vol.14 (1), p.8491-8491, Article 8491
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ArticlesPeer ReviewedFull Text
Hexokinases inhibit death receptor–dependent apoptosis on the mitochondria
Author / Creator:Lauterwasser, Joachim ; Fimm-Todt, Franziska ; Oelgeklaus, Aline ; Schreiner, Annabell ; Funk, Kathrin ; Falquez-Medina, Hugo ; Klesse, Ramona ; Jahreis, Günther ; Zerbes, Ralf M. ; O’Neill, Katelyn ; van der Laan, Martin ; Luo, Xu ; Edlich, Frank
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (33), p.1-10
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ArticlesPeer ReviewedFull Text
Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity
Author / Creator:Zhitomirsky, Benny ; Yunaev, Anna ; Kreiserman, Roman ; Kaplan, Ariel ; Stark, Michal ; Assaraf, Yehuda G.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-12, Vol.9 (12), p.1191-15, Article 1191
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Deciphering the mechanism of calcineurin inhibitor‐induced hypertension
Author / Creator:Kortenoeven, Marleen L. A.
Publisher:England: Wiley Subscription Services, Inc
Journal title:Acta Physiologica, 2023-06, Vol.238 (2), p.e13976-n/a
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Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion
Author / Creator:Olauson, Hannes ; Lindberg, Karolina ; Amin, Risul ; Sato, Tadatoshi ; Jia, Ting ; Goetz, Regina ; Mohammadi, Moosa ; Andersson, Göran ; Lanske, Beate ; Larsson, Tobias E.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-12, Vol.9 (12), p.e1003975
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ArticlesPeer ReviewedFull Text
Clinical Pharmacokinetics and Pharmacodynamics of Voclosporin
Author / Creator:Abdel-Kahaar, Emaad ; Keller, Frieder
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2023-05, Vol.62 (5), p.693-703
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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A
Author / Creator:Faul, Christian ; Donnelly, Mary ; Merscher-Gomez, Sandra ; Chang, Yoon Hee ; Franz, Stefan ; Delfgaauw, Jacqueline ; Chang, Jer-Ming ; Choi, Hoon Young ; Campbell, Kirk N ; Kim, Kwanghee ; Reiser, Jochen ; Mundel, Peter
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2008-09, Vol.14 (9), p.931-938
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The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin
Author / Creator:Grigoriu, Simina ; Bond, Rachel ; Cossio, Pilar ; Chen, Jennifer A. ; Ly, Nina ; Hummer, Gerhard ; Page, Rebecca ; Cyert, Martha S. ; Peti, Wolfgang
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2013-02, Vol.11 (2), p.e1001492-e1001492
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Proteinuria: an enzymatic disease of the podocyte?
Author / Creator:Mundel, Peter ; Reiser, Jochen
Publisher:Basingstoke: Elsevier Inc
Journal title:Kidney international, 2010-04, Vol.77 (7), p.571-580
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A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity
Author / Creator:Kimchi-Sarfaty, Chava ; Oh, Jung Mi ; Kim, In-Wha ; Sauna, Zuben E. ; Calcagno, Anna Maria ; Ambudkar, Suresh V. ; Gottesman, Michael M.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2007-01, Vol.315 (5811), p.525-528
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Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19
Author / Creator:Parkinson, Nicholas ; Rodgers, Natasha ; Head Fourman, Max ; Wang, Bo ; Zechner, Marie ; Swets, Maaike C. ; Millar, Jonathan E. ; Law, Andy ; Russell, Clark D. ; Baillie, J. Kenneth ; Clohisey, Sara
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.22303-22303, Article 22303
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Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A

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Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter

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Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase

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Voclosporin: First Approval: Voclosporin: First Approval

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Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways

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Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive

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The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors

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Screening of tau protein kinase inhibitors in a tauopathy-relevant cell-based model of tau hyperphosphorylation and oligomerization

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CaMKII determines mitochondrial stress responses in heart

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Cyclosporine A-resistant CAR-T cells mediate antitumour immunity in the presence of allogeneic cells

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Hexokinases inhibit death receptor–dependent apoptosis on the mitochondria

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Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity

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Deciphering the mechanism of calcineurin inhibitor‐induced hypertension

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Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion

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Clinical Pharmacokinetics and Pharmacodynamics of Voclosporin

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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

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The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

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Proteinuria: an enzymatic disease of the podocyte?

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A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity

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Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19

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