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428 results for Cytochrome+P-450+CYP2D6+-+metabolism

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Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group
Author / Creator:Caudle, Kelly E. ; Sangkuhl, Katrin ; Whirl‐Carrillo, Michelle ; Swen, Jesse J. ; Haidar, Cyrine E. ; Klein, Teri E. ; Gammal, Roseann S. ; Relling, Mary V. ; Scott, Stuart A. ; Hertz, Daniel L. ; Guchelaar, Henk‐Jan ; Gaedigk, Andrea
Publisher:United States: John Wiley and Sons Inc
Journal title:Clinical and translational science, 2020-01, Vol.13 (1), p.116-124
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Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria
Author / Creator:Lacerda, Marcus V.G ; Llanos-Cuentas, Alejandro ; Krudsood, Srivicha ; Lon, Chanthap ; Saunders, David L ; Mohammed, Rezika ; Yilma, Daniel ; Batista Pereira, Dhelio ; Espino, Fe E.J ; Mia, Reginaldo Z ; Chuquiyauri, Raul ; Val, Fernando ; Casapía, Martín ; Monteiro, Wuelton M ; Brito, Marcelo A.M ; Costa, Mônica R.F ; Buathong, Nillawan ; Noedl, Harald ; Diro, Ermias ; Getie, Sisay ; Wubie, Kalehiwot M ; Abdissa, Alemseged ; Zeynudin, Ahmed ; Abebe, Cherinet ; Tada, Mauro S ; Brand, Françoise ; Beck, Hans-Peter ; Angus, Brian ; Duparc, Stephan ; Kleim, Jörg-Peter ; Kellam, Lynda M ; Rousell, Victoria M ; Jones, Siôn W ; Hardaker, Elizabeth ; Mohamed, Khadeeja ; Clover, Donna D ; Fletcher, Kim ; Breton, John J ; Ugwuegbulam, Cletus O ; Green, Justin A ; Koh, Gavin C.K.W
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-01, Vol.380 (3), p.215-228
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A Review of the Important Role of CYP2D6 in Pharmacogenomics
Author / Creator:Taylor, Christopher ; Crosby, Ian ; Yip, Vincent ; Maguire, Peter ; Pirmohamed, Munir ; Turner, Richard M.
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2020-10, Vol.11 (11), p.1295
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Antimalarial activity of primaquine operates via a two-step biochemical relay
Author / Creator:Camarda, Grazia ; Jirawatcharadech, Piyaporn ; Priestley, Richard S. ; Saif, Ahmed ; March, Sandra ; Wong, Michael H. L. ; Leung, Suet ; Miller, Alex B. ; Baker, David A. ; Alano, Pietro ; Paine, Mark J. I. ; Bhatia, Sangeeta N. ; O’Neill, Paul M. ; Ward, Stephen A. ; Biagini, Giancarlo A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3226-9, Article 3226
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Primaquine Failure and Cytochrome P-450 2D6 in Plasmodium vivax Malaria
Author / Creator:Bennett, Jason W ; Pybus, Brandon S ; Yadava, Anjali ; Tosh, Donna ; Sousa, Jason C ; McCarthy, William F ; Deye, Gregory ; Melendez, Victor ; Ockenhouse, Christian F
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-10, Vol.369 (14), p.1381-1382
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Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
Author / Creator:Li, Danyang ; Pain, Oliver ; Fabbri, Chiara ; Wong, Win Lee Edwin ; Lo, Chris Wai Hang ; Ripke, Stephan ; Cattaneo, Annamaria ; Souery, Daniel ; Dernovsek, Mojca Z. ; Henigsberg, Neven ; Hauser, Joanna ; Lewis, Glyn ; Mors, Ole ; Perroud, Nader ; Rietschel, Marcella ; Uher, Rudolf ; Maier, Wolfgang ; Baune, Bernhard T. ; Biernacka, Joanna M. ; Bondolfi, Guido ; Domschke, Katharina ; Kato, Masaki ; Liu, Yu-Li ; Serretti, Alessandro ; Tsai, Shih-Jen ; Weinshilboum, Richard ; McIntosh, Andrew M. ; Lewis, Cathryn M.
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2024-07, Vol.14 (1), p.296-8, Article 296
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Dutch pharmacogenetics working group (DPWG) guideline for the gene-drug interaction of CYP2D6 and COMT with atomoxetine and methylphenidate
Author / Creator:Nijenhuis, Marga ; Soree, Bianca ; Jama, Wafa O. M. ; de Boer-Veger, Nienke J. ; Buunk, Anne Marie ; Guchelaar, Henk-Jan ; Houwink, Elisa J. F. ; Rongen, Gerard A. ; van Schaik, Ron H. N. ; Swen, Jesse J. ; Touw, Daan ; van der Weide, Jan ; van Westrhenen, Roos ; Deneer, Vera H. M. ; Risselada, Arne
Publisher:England: Nature Publishing Group
Journal title:European journal of human genetics : EJHG, 2023-12, Vol.31 (12), p.1364-1370
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Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone)
Author / Creator:Matic, Maja ; Nijenhuis, Marga ; Soree, Bianca ; de Boer-Veger, Nienke J. ; Buunk, Anne-Marie ; Houwink, Elisa J. F. ; Mulder, Hans ; Rongen, Gerard A. P. J. M. ; Weide, Jan van der ; Wilffert, Bob ; Swen, Jesse J. ; Guchelaar, Henk-Jan ; Deneer, Vera H. M. ; van Schaik, Ron H. N.
Publisher:England: Nature Publishing Group
Journal title:European journal of human genetics : EJHG, 2022-10, Vol.30 (10), p.1105-1113
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Pharmacogenetics of drug-drug interaction and drug-drug-gene interaction: a systematic review on CYP2C9, CYP2C19 and CYP2D6
Author / Creator:Bahar, Muh Akbar ; Setiawan, Didik ; Hak, Eelko ; Wilffert, Bob
Publisher:England: Future Medicine Ltd
Journal title:Pharmacogenomics, 2017-05, Vol.18 (7), p.701-739
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Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently
Author / Creator:Duthaler, Urs ; Bachmann, Fabio ; Suenderhauf, Claudia ; Grandinetti, Tanja ; Pfefferkorn, Florian ; Haschke, Manuel ; Hruz, Petr ; Bouitbir, Jamal ; Krähenbühl, Stephan
Publisher:Switzerland: Springer Nature B.V
Journal title:Clinical pharmacokinetics, 2022-07, Vol.61 (7), p.1039-1055
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Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling
Author / Creator:Kratochwil, Nicole A. ; Meille, Christophe ; Fowler, Stephen ; Klammers, Florian ; Ekiciler, Aynur ; Molitor, Birgit ; Simon, Sandrine ; Walter, Isabelle ; McGinnis, Claudia ; Walther, Johanna ; Leonard, Brian ; Triyatni, Miriam ; Javanbakht, Hassan ; Funk, Christoph ; Schuler, Franz ; Lavé, Thierry ; Parrott, Neil J.
Publisher:New York: Springer US
Journal title:The AAPS journal, 2017-03, Vol.19 (2), p.534-550
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Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes
Author / Creator:Numanagić, Ibrahim ; Malikić, Salem ; Ford, Michael ; Qin, Xiang ; Toji, Lorraine ; Radovich, Milan ; Skaar, Todd C. ; Pratt, Victoria M. ; Berger, Bonnie ; Scherer, Steve ; Sahinalp, S. Cenk
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-02, Vol.9 (1), p.828-11, Article 828
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Therapeutic Drug Monitoring of Endoxifen for Tamoxifen Precision Dosing: Feasible in Patients with Hormone-Sensitive Breast Cancer
Author / Creator:Braal, C. Louwrens ; Jager, Agnes ; Hoop, Esther Oomen-de ; Westenberg, Justin D. ; Lommen, Koen M. W. T. ; de Bruijn, Peter ; Vastbinder, Mijntje B. ; van Rossum-Schornagel, Quirine C. ; Thijs-Visser, Martine F. ; van Alphen, Robbert J. ; Struik, Liesbeth E. M. ; Zuetenhorst, Hanneke J. M. ; Mathijssen, Ron H. J. ; Koolen, Stijn L. W.
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2022-04, Vol.61 (4), p.527-537
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Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance: Part I
Author / Creator:Zhou, Shu-Feng
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2009-11, Vol.48 (11), p.689-723
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Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype
Author / Creator:Wollmann, Birgit M. ; Størset, Elisabet ; Kringen, Marianne Kristiansen ; Molden, Espen ; Smith, Robert L.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of clinical pharmacology, 2023-04, Vol.79 (4), p.523-531
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Association of initiating CYP2D6-metabolized opioids with risks of adverse outcomes in older adults receiving antidepressants: A retrospective cohort study
Author / Creator:Wei, Yu-Jung Jenny ; Winterstein, Almut G ; Schmidt, Siegfried ; Fillingim, Roger B ; Daniels, Michael J ; DeKosky, Steven T ; Schmidt, Stephan
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2025-06, Vol.22 (6), p.e1004620
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Transfer learning enables prediction of CYP2D6 haplotype function
Author / Creator:McInnes, Gregory ; Dalton, Rachel ; Sangkuhl, Katrin ; Whirl-Carrillo, Michelle ; Lee, Seung-been ; Tsao, Philip S. ; Gaedigk, Andrea ; Altman, Russ B. ; Woodahl, Erica L.
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2020-11, Vol.16 (11), p.e1008399
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A Phase I, Open-Label, Fixed Sequence Study to Investigate the Effect of Cytochrome P450 2D6 Inhibition on the Pharmacokinetics of Ulotaront in Healthy Subjects
Author / Creator:Tsukada, Hironobu ; Chen, Yu-Luan ; Xiao, Guangqing ; Lennek, Lisa ; Milanovic, Snezana M. ; Worden, MaryAlice ; Polhamus, Daniel G. ; Chiu, Yu-Yuan ; Hopkins, Seth C. ; Galluppi, Gerald R.
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2023-12, Vol.62 (12), p.1755-1763
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Codeine, Ultrarapid-Metabolism Genotype, and Postoperative Death
Author / Creator:Lauwers, Albert E ; Koren, Gideon ; Phillips, Michael S ; Ciszkowski, Catherine ; Madadi, Parvaz
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2009-08, Vol.361 (8), p.827-828
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CYP2D6 and tamoxifen: DNA matters in breast cancer
Author / Creator:Hoskins, Janelle M. ; Carey, Lisa A. ; McLeod, Howard L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2009-08, Vol.9 (8), p.576-586
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Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group

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Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria

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A Review of the Important Role of CYP2D6 in Pharmacogenomics

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Antimalarial activity of primaquine operates via a two-step biochemical relay

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Primaquine Failure and Cytochrome P-450 2D6 in Plasmodium vivax Malaria

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Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis

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Dutch pharmacogenetics working group (DPWG) guideline for the gene-drug interaction of CYP2D6 and COMT with atomoxetine and methylphenidate

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Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone)

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Pharmacogenetics of drug-drug interaction and drug-drug-gene interaction: a systematic review on CYP2C9, CYP2C19 and CYP2D6

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Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently

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Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling

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Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes

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Therapeutic Drug Monitoring of Endoxifen for Tamoxifen Precision Dosing: Feasible in Patients with Hormone-Sensitive Breast Cancer

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Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance: Part I

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Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype

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Association of initiating CYP2D6-metabolized opioids with risks of adverse outcomes in older adults receiving antidepressants: A retrospective cohort study

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Transfer learning enables prediction of CYP2D6 haplotype function

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A Phase I, Open-Label, Fixed Sequence Study to Investigate the Effect of Cytochrome P450 2D6 Inhibition on the Pharmacokinetics of Ulotaront in Healthy Subjects

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Codeine, Ultrarapid-Metabolism Genotype, and Postoperative Death

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CYP2D6 and tamoxifen: DNA matters in breast cancer

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