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ArticlesPeer ReviewedFull Text
Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice
Author / Creator:Challis, Collin ; Hori, Acacia ; Sampson, Timothy R. ; Yoo, Bryan B. ; Challis, Rosemary C. ; Hamilton, Adam M. ; Mazmanian, Sarkis K. ; Volpicelli-Daley, Laura A. ; Gradinaru, Viviana
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2020-03, Vol.23 (3), p.327-336
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Immunogenicity of glycans on biotherapeutic drugs produced in plant expression systems—The taliglucerase alfa story
Author / Creator:Rup, Bonita ; Alon, Sari ; Amit-Cohen, Bat-Chen ; Brill Almon, Einat ; Chertkoff, Raul ; Tekoah, Yoram ; Rudd, Pauline M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-10, Vol.12 (10), p.e0186211-e0186211
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ArticlesPeer ReviewedFull Text
The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture
Author / Creator:Naphatsamon, Uthailak ; Ohashi, Takao ; Misaki, Ryo ; Fujiyama, Kazuhito
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-07, Vol.19 (7), p.1972
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ArticlesPeer ReviewedFull Text
Production and Purification of Recombinant Glucocerebrosidase in Transgenic Rice Cell Suspension Cultures
Author / Creator:Nam, Hyung-Jin ; Kwon, Jun-Young ; Choi, Hong-Yeol ; Kang, Seung-Hoon ; Jung, Hahn-Sun ; Kim, Dong-Il
Publisher:New York: Springer US
Journal title:Applied biochemistry and biotechnology, 2017-04, Vol.181 (4), p.1401-1415
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ArticlesPeer ReviewedFull Text
Transgenic plants as factories for biopharmaceuticals
Author / Creator:Giddings, Glynis ; Allison, Gordon ; Brooks, Douglas ; Carter, Adrian
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2000-11, Vol.18 (11), p.1151-1155
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ArticlesPeer ReviewedFull Text
Ubiquitous Transgene Expression of the Glucosylceramide-Synthesizing Enzyme Accelerates Glucosylceramide Accumulation and Storage Cells in a Gaucher Disease Mouse Model
Author / Creator:Barnes, Sonya ; Xu, You-Hai ; Zhang, Wujuan ; Liou, Benjamin ; Setchell, Kenneth D. R. ; Bao, Liming ; Grabowski, Gregory A. ; Sun, Ying
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-12, Vol.9 (12), p.e116023-e116023
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ArticlesPeer ReviewedFull Text
Transient Expression of Functional Glucocerebrosidase for Treatment of Gaucher’s Disease in the Goat Mammary Gland
Author / Creator:Tavares, Kaio Cesar Simiano ; Dias, Ana Christina de Oliveira ; Lazzarotto, Cícera Regina ; Gaudencio Neto, Saul ; de Sá Carneiro, Igor ; Ongaratto, Felipe Ledur ; Pinto, Antônio Frederico Michel ; de Aguiar, Luís Henrique ; Calderón, Carlos Enrique Mendez ; Toledo, Jorge Roberto ; Castro, Fidel Ovidio ; Santos, Diogenes Santiago ; Chies, Jocelei Maria ; Bertolini, Marcelo ; Bertolini, Luciana Relly
Publisher:New York: Springer US
Journal title:Molecular biotechnology, 2016-01, Vol.58 (1), p.47-55
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ArticlesPeer ReviewedFull Text
Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase
Author / Creator:Morganti, Ligia ; Novo, Juliana Branco ; Moro, Ana Maria ; Paes Leme, Adriana Franco ; Serrano, Solange Maria de Toledo ; Raw, Isaias ; Ho, Paulo Lee
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:BioMed research international, 2012-01, Vol.2012 (2012), p.1-10
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ArticlesPeer ReviewedFull Text
Munchausen syndrome by proxy mimicking as Gaucher disease
Author / Creator:Al-Owain, Mohammed ; Al-Zaidan, Hamad ; Al-Hashem, Amal ; Kattan, Hoda ; Al-Dowaish, Abdullah
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:European journal of pediatrics, 2010-08, Vol.169 (8), p.1029-1032
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ArticlesPeer ReviewedFull Text
Mice with Type 2 and 3 Gaucher Disease Point Mutations Generated by a Single Insertion Mutagenesis Procedure (SIMP)
Author / Creator:Liu, Yujing ; Suzuki, Kinuko ; Reed, Jennifer D. ; Grinberg, Alexander ; Westphal, Heiner ; Hoffmann, Alexander ; Doring, Thomas ; Sandhoff, Konrad ; Proia, Richard L.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (5), p.2503-2508
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ArticlesPeer ReviewedFull Text
Secretion of human glucocerebrosidase from stable transformed insect cells using native signal sequences
Author / Creator:Sinclair, Graham ; Pfeifer, Tom A ; Grigliatti, Thomas A ; Choy, Francis Y.M
Publisher:Ottawa, Canada: NRC Research Press
Journal title:Biochemistry and cell biology, 2006-04, Vol.84 (2), p.148-156
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ArticlesPeer ReviewedFull Text
Transient expression of wild-type and mutant glucocerebrosidases in hybrid vaccinia expression system
Author / Creator:Hodaňová, Kateřina ; Mělková, Zora ; Horowitz, Mia ; Hřebíček, Martin
Publisher:Cham: Springer International Publishing
Journal title:European journal of human genetics : EJHG, 2003-05, Vol.11 (5), p.369-374
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ArticlesPeer ReviewedFull Text
Long-Term in vivo Expression of the Human Glucocerebrosidase Gene in Nonhuman Primates After CD34+Hematopoietic Cell Transduction with Cell-Free Retroviral Vector Preparations
Author / Creator:Xu, L. C. ; Karlsson, S. ; Byrne, E. R. ; Kluepfel-Stahl, S. ; Kessler, S. W. ; Agricola, B. A. ; Sellers, S. ; Kirby, M. ; Dunbar, C. E. ; Brady, R. O. ; Nienhuis, A. W. ; Donahue, R. E.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1995-05, Vol.92 (10), p.4372-4376
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ArticlesPeer ReviewedFull Text
Selection of Transduced CD34+Progenitors and Enzymatic Correction of Cells from Gaucher Patients, with Bicistronic Vectors
Author / Creator:Migita, M ; Medin, J A ; Pawliuk, R ; Jacobson, S ; Nagle, J W ; Anderson, S ; Amiri, M ; Humphries, R K ; Karlsson, S
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (26), p.12075-12079
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ArticlesPeer ReviewedFull Text
Production of Human Glucocerebrosidase in Mice after Retroviral Gene Transfer into Multipotential Hematopoietic Progenitor Cells
Author / Creator:Correll, Pamela H. ; Fink, John K. ; Brady, Roscoe O. ; Perry, Leland K. ; Karlsson, Stefan
Publisher:Washington, DC: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1989-11, Vol.86 (22), p.8912-8916
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Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice

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Immunogenicity of glycans on biotherapeutic drugs produced in plant expression systems—The taliglucerase alfa story

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The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

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Production and Purification of Recombinant Glucocerebrosidase in Transgenic Rice Cell Suspension Cultures

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Transgenic plants as factories for biopharmaceuticals

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Ubiquitous Transgene Expression of the Glucosylceramide-Synthesizing Enzyme Accelerates Glucosylceramide Accumulation and Storage Cells in a Gaucher Disease Mouse Model

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Transient Expression of Functional Glucocerebrosidase for Treatment of Gaucher’s Disease in the Goat Mammary Gland

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Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase

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Munchausen syndrome by proxy mimicking as Gaucher disease

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Mice with Type 2 and 3 Gaucher Disease Point Mutations Generated by a Single Insertion Mutagenesis Procedure (SIMP)

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Secretion of human glucocerebrosidase from stable transformed insect cells using native signal sequences

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Transient expression of wild-type and mutant glucocerebrosidases in hybrid vaccinia expression system

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Long-Term in vivo Expression of the Human Glucocerebrosidase Gene in Nonhuman Primates After CD34+Hematopoietic Cell Transduction with Cell-Free Retroviral Vector Preparations

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Selection of Transduced CD34+Progenitors and Enzymatic Correction of Cells from Gaucher Patients, with Bicistronic Vectors

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Production of Human Glucocerebrosidase in Mice after Retroviral Gene Transfer into Multipotential Hematopoietic Progenitor Cells

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