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ArticlesPeer ReviewedFull Text
Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease
Author / Creator:Sobue, Akira ; Komine, Okiru ; Hara, Yuichiro ; Endo, Fumito ; Mizoguchi, Hiroyuki ; Watanabe, Seiji ; Murayama, Shigeo ; Saito, Takashi ; Saido, Takaomi C. ; Sahara, Naruhiko ; Higuchi, Makoto ; Ogi, Tomoo ; Yamanaka, Koji
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2021-01, Vol.9 (1), p.1-1, Article 1
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Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer’s Disease
Author / Creator:Baligács, Nóra ; Albertini, Giulia ; Borrie, Sarah C. ; Serneels, Lutgarde ; Pridans, Clare ; Balusu, Sriram ; De Strooper, Bart
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-12, Vol.15 (1), p.10634-14, Article 10634
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Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in Toxoplasma gondii-Infected Alzheimer’s Disease Model Mice
Author / Creator:Shin, Ji-Hun ; Hwang, Young Sang ; Jung, Bong-Kwang ; Seo, Seung-Hwan ; Ham, Do-Won ; Shin, Eun-Hee
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2021-03, Vol.22 (5), p.2764
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Single cell nuclei transcriptomics of human brains identify a role for homeostatic microglia in cellular senescence in Alzheimer’s disease
Author / Creator:Yassine, Hussein N ; Li, Boyang ; Wang, Shaowei ; Ebright, Brandon ; Duro, Marlon Vincent V. ; Kerman, Bilal Ersen ; Asante, Isaac ; Arvanitakis, Zoe ; Louie, Stan G
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S1), p.n/a
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Loss of Homeostatic Microglia Signature in Prion Diseases
Author / Creator:Wang, Yue ; Hartmann, Kristin ; Thies, Edda ; Mohammadi, Behnam ; Altmeppen, Hermann ; Sepulveda-Falla, Diego ; Glatzel, Markus ; Krasemann, Susanne
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-09, Vol.11 (19), p.2948
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Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment
Author / Creator:van Wageningen, Thecla A. ; Vlaar, Eva ; Kooij, Gijs ; Jongenelen, Cornelis A. M. ; Geurts, Jeroen J. G. ; van Dam, Anne-Marie
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2019-12, Vol.7 (1), p.206-206, Article 206
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Neuroinflammation in Alzheimer's disease: microglial signature and their relevance to disease
Author / Creator:Sobue, Akira ; Komine, Okiru ; Yamanaka, Koji
Publisher:England: BioMed Central
Journal title:Inflammation and regeneration, 2023-05, Vol.43 (1), p.26-26
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Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease
Author / Creator:Noguchi, Hideko ; Koyama, Sachiko ; Yagita, Kaoru ; Shijo, Masahiro ; Matsuzono, Kosuke ; Hamasaki, Hideomi ; Kanemaru, Takaaki ; Okamoto, Tsuyoshi ; Kai, Keita ; Aishima, Shinichi ; Abe, Koji ; Sasagasako, Naokazu ; Honda, Hiroyuki
Publisher:England: Oxford University Press
Journal title:Journal of neuropathology and experimental neurology, 2023-01, Vol.82 (1), p.38-48
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Newsletter articlesFull Text
"Reprogramming Cells Into Homeostatic Microglia" in Patent Application Approval Process (USPTO 20220411751)
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2023, p.5298
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Newsletter articlesFull Text
Transcriptomically unique endolysosomal and homeostatic microglia populations in Alzheimer's disease and aged human brain (Updated November 18, 2022)
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2022, p.7611
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Newsletter articlesFull Text
University of Massachusetts issued patent titled "Reprogramming Cells Into Homeostatic Microglia"
Publisher:Melbourne: News Bites Pty Ltd
Journal title:News Bites - Private Companies, 2023
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Newsletter articlesFull Text
INTERNATIONAL PATENT: THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , UNIVERSITY OF MASSACHUSETTS , MASSACHUSETTS INSTITUTE OF TECHNOLOGY , BUTOVSKY, OLEG , LITVAK, VLADIMIR , RALVENIUS, WILLIAM , TSAI, LI-H...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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Newsletter articlesFull Text
Research on Toxoplasma gondii Described by Researchers at Seoul National University College of Medicine (Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in Toxoplasma gondii -Infecte...
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2021, p.5740
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ArticlesPeer ReviewedFull Text
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease
Author / Creator:Rangaraju, Srikant ; Dammer, Eric B. ; Raza, Syed Ali ; Rathakrishnan, Priyadharshini ; Xiao, Hailian ; Gao, Tianwen ; Duong, Duc M. ; Pennington, Michael W. ; Lah, James J. ; Seyfried, Nicholas T. ; Levey, Allan I.
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2018-05, Vol.13 (1), p.24-24, Article 24
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ArticlesPeer ReviewedFull Text
Reparative Effects of Stem Cell Factor and Granulocyte Colony-Stimulating Factor in Aged APP/PS1 Mice
Author / Creator:Guo, Xingzhi ; Liu, Yanying ; Morgan, David ; Zhao, Li-Ru
Publisher:United States: JKL International
Journal title:Aging and disease, 2020-12, Vol.11 (6), p.1423-1443
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Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region
Author / Creator:Schlepckow, Kai ; Monroe, Kathryn M ; Kleinberger, Gernot ; Cantuti‐Castelvetri, Ludovico ; Parhizkar, Samira ; Xia, Dan ; Willem, Michael ; Werner, Georg ; Pettkus, Nadine ; Brunner, Bettina ; Sülzen, Alice ; Nuscher, Brigitte ; Hampel, Heike ; Xiang, Xianyuan ; Feederle, Regina ; Tahirovic, Sabina ; Park, Joshua I ; Prorok, Rachel ; Mahon, Cathal ; Liang, Chun‐Chi ; Shi, Ju ; Kim, Do Jin ; Sabelström, Hanna ; Huang, Fen ; Di Paolo, Gilbert ; Simons, Mikael ; Lewcock, Joseph W ; Haass, Christian
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2020-04, Vol.12 (4), p.e11227-n/a
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ArticlesPeer ReviewedFull Text
Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease
Author / Creator:Xu, Yi-Jun ; Au, Ngan Pan Bennett ; Ma, Chi Him Eddie
Publisher:Lausanne: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2022-05
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AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease
Author / Creator:Kim, Yi Sak ; Choi, Soo-Ho ; Kim, Keun-Young ; Navia-Pelaez, Juliana M. ; Perkins, Guy A. ; Choi, Seunghwan ; Kim, Jungsu ; Nazarenkov, Nicolaus ; Rissman, Robert A. ; Ju, Won-Kyu ; Ellisman, Mark H. ; Miller, Yury I.
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2024-09, Vol.21 (1), p.245-16, Article 245
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Microglial signatures and their role in health and disease
Author / Creator:Butovsky, Oleg ; Weiner, Howard L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Neuroscience, 2018-10, Vol.19 (10), p.622-635
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Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection
Author / Creator:Quintana, Juan F. ; Chandrasegaran, Praveena ; Sinton, Matthew C. ; Briggs, Emma M. ; Otto, Thomas D. ; Heslop, Rhiannon ; Bentley-Abbot, Calum ; Loney, Colin ; de Lecea, Luis ; Mabbott, Neil A. ; MacLeod, Annette
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-09, Vol.13 (1), p.5752-5752, Article 5752
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Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease

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Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer’s Disease

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Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in Toxoplasma gondii-Infected Alzheimer’s Disease Model Mice

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Single cell nuclei transcriptomics of human brains identify a role for homeostatic microglia in cellular senescence in Alzheimer’s disease

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Loss of Homeostatic Microglia Signature in Prion Diseases

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Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

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Neuroinflammation in Alzheimer's disease: microglial signature and their relevance to disease

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Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease

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"Reprogramming Cells Into Homeostatic Microglia" in Patent Application Approval Process (USPTO 20220411751)

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Transcriptomically unique endolysosomal and homeostatic microglia populations in Alzheimer's disease and aged human brain (Updated November 18, 2022)

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University of Massachusetts issued patent titled "Reprogramming Cells Into Homeostatic Microglia"

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INTERNATIONAL PATENT: THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , UNIVERSITY OF MASSACHUSETTS , MASSACHUSETTS INSTITUTE OF TECHNOLOGY , BUTOVSKY, OLEG , LITVAK, VLADIMIR , RALVENIUS, WILLIAM , TSAI, LI-H...

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Research on Toxoplasma gondii Described by Researchers at Seoul National University College of Medicine (Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in Toxoplasma gondii -Infecte...

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Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

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Reparative Effects of Stem Cell Factor and Granulocyte Colony-Stimulating Factor in Aged APP/PS1 Mice

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Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region

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Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease

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AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

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Microglial signatures and their role in health and disease

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Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection

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