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ArticlesPeer ReviewedFull Text
Cohesin is required for long-range enhancer action at the Shh locus
Author / Creator:Kane, Lauren ; Williamson, Iain ; Flyamer, Ilya M. ; Kumar, Yatendra ; Hill, Robert E. ; Lettice, Laura A. ; Bickmore, Wendy A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2022-09, Vol.29 (9), p.891-897
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Deletion of CTCF sites in the SHH locus alters enhancer–promoter interactions and leads to acheiropodia
Author / Creator:Ushiki, Aki ; Zhang, Yichi ; Xiong, Chenling ; Zhao, Jingjing ; Georgakopoulos-Soares, Ilias ; Kane, Lauren ; Jamieson, Kirsty ; Bamshad, Michael J. ; Nickerson, Deborah A. ; Shen, Yin ; Lettice, Laura A. ; Silveira-Lucas, Elizabeth Lemos ; Petit, Florence ; Ahituv, Nadav
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-04, Vol.12 (1), p.2282-12, Article 2282
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Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
Author / Creator:Martínez-Estrada, Ofelia M ; Lettice, Laura A ; Essafi, Abdelkader ; Guadix, Juan Antonio ; Slight, Joan ; Velecela, Víctor ; Hall, Emma ; Reichmann, Judith ; Devenney, Paul S ; Hohenstein, Peter ; Hosen, Naoki ; Hill, Robert E ; Muñoz-Chapuli, Ramón ; Hastie, Nicholas D
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2010-01, Vol.42 (1), p.89-93
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Alterations to the remote control of Shh gene expression cause congenital abnormalities
Author / Creator:Hill, Robert E. ; Lettice, Laura A.
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2013-06, Vol.368 (1620), p.20120357-20120357
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Use of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development
Author / Creator:Kinsella, Elaine ; Dora, Natalie ; Mellis, David ; Lettice, Laura ; Deveney, Paul ; Hill, Robert ; Ditzel, Mark
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0157079
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Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice
Author / Creator:Zhou, Yu S. ; Webb, Sheila ; Lettice, Laura ; Tardif, Steve ; Kilanowski, Fiona ; Tyrrell, Christine ; MacPherson, Heather ; Semple, Fiona ; Tennant, Peter ; Baker, Tina ; Hart, Alan ; Devenney, Paul ; Perry, Paul ; Davey, Tracey ; Barran, Perdita ; Barratt, Chris L. ; Dorin, Julia R.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-10, Vol.9 (10), p.e1003826
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Disruption of a Long-Range Cis-Acting Regulator for Shh Causes Preaxial Polydactyly
Author / Creator:Lettice, Laura A. ; Horikoshi, Taizo ; Simon J. H. Heaney ; van Baren, Marijke J. ; van der Linde, Herma C. ; Breedveld, Guido J. ; Joosse, Marijke ; Akarsu, Nurten ; Oostra, Ben A. ; Endo, Naoto ; Shibata, Minoru ; Suzuki, Mikio ; Takahashi, Eiichi ; Shinka, Toshikatsu ; Nakahori, Yutaka ; Ayusawa, Dai ; Nakabayashi, Kazuhiko ; Scherer, Stephen W. ; Heutink, Peter ; Hill, Robert E. ; Noji, Sumihare
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (11), p.7548-7553
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Human β-Defensin 3 [corrected] Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid
Author / Creator:Semple, Fiona ; MacPherson, Heather ; Webb, Sheila ; Kilanowski, Fiona ; Lettice, Laura ; McGlasson, Sarah L ; Wheeler, Ann P ; Chen, Valerie ; Millhauser, Glenn L ; Melrose, Lauren ; Davidson, Donald J ; Dorin, Julia R
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS genetics, 2015-12, Vol.11 (12), p.e1005673-e1005673
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Correction: Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid
Author / Creator:Semple, Fiona ; MacPherson, Heather ; Webb, Sheila ; Kilanowski, Fiona ; Lettice, Laura ; McGlasson, Sarah L. ; Wheeler, Ann P. ; Chen, Valerie ; Millhauser, Glenn L. ; Melrose, Lauren ; Davidson, Donald J. ; Dorin, Julia R.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2016-01, Vol.12 (1), p.e1005801-e1005801
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ArticlesPeer ReviewedFull Text
The Mouse Bagpipe Gene Controls Development of Axial Skeleton, Skull, and Spleen
Author / Creator:Lettice, Laura A. ; Purdie, Lorna A. ; Carlson, Geoffrey J. ; Kilanowski, Fiona ; Dorin, Julia ; Hill, Robert E.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (17), p.9695-9700
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ArticlesPeer ReviewedFull Text
Alterations to the remote control of Shh gene expression cause congenital abnormalities
Author / Creator:Hill, Robert E. ; Lettice, Laura A.
Publisher:The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2013-06, Vol.368 (1620), p.1-6
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ArticlesPeer ReviewedFull Text
Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid
Author / Creator:Semple, Fiona ; MacPherson, Heather ; Webb, Sheila ; Kilanowski, Fiona ; Lettice, Laura ; McGlasson, Sarah L. ; Wheeler, Ann P. ; Chen, Valerie ; Millhauser, Glenn L. ; Melrose, Lauren ; Davidson, Donald J. ; Dorin, Julia R.
Publisher:San Francisco, CA USA: Public Library of Science
Journal title:PLoS genetics, 2015-12, Vol.11 (12), p.e1005673
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ArticlesFull Text
Developmentally regulated Shh expression is robust to TAD perturbations
Author / Creator:Williamson, Iain ; Kane, Lauren ; Devenney, Paul S ; Anderson, Eve ; Kilanowski, Fiona ; Hill, Robert E ; Bickmore, Wendy ; Lettice, Laura
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-04
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ArticlesPeer ReviewedFull Text
Human [Beta]-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid: e1005673
Author / Creator:Semple, Fiona ; MacPherson, Heather ; Webb, Sheila ; Kilanowski, Fiona ; Lettice, Laura ; McGlasson, Sarah L ; Wheeler, Ann P ; Chen, Valerie ; Millhauser, Glenn L ; Melrose, Lauren ; Davidson, Donald J ; Dorin, Julia R
Publisher:San Francisco: Public Library of Science
Journal title:PLoS genetics, 2015-12, Vol.11 (12)
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Shh and ZRS enhancer co-localisation is specific to the zone of polarizing activity
Author / Creator:Williamson, William Iain ; Lettice, Laura A ; Hill, Robert ; Bickmore, Wendy A
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2016-04
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ArticlesPeer ReviewedFull Text
Partial Deletion of Chromosome 8 [beta]-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice: e1003826
Author / Creator:Zhou, Yu S ; Webb, Sheila ; Lettice, Laura ; Tardif, Steve ; Kilanowski, Fiona ; Tyrrell, Christine ; MacPherson, Heather ; Semple, Fiona ; Tennant, Peter ; Baker, Tina ; Hart, Alan ; Devenney, Paul ; Perry, Paul ; Davey, Tracey ; Barran, Perdita ; Barratt, Chris L ; Dorin, Julia R
Publisher:San Francisco: Public Library of Science
Journal title:PLoS genetics, 2013-10, Vol.9 (10)
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ArticlesPeer ReviewedFull Text
Human [Beta]-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid
Author / Creator:Semple, Fiona ; Heather MacPherson ; Webb, Sheila ; Kilanowski, Fiona ; Lettice, Laura ; McGlasson, Sarah ; Wheeler, Ann ; Chen, Valerie ; Millhauser, Glenn ; Melrose, Lauren ; Davidson, Donald ; Dorin, Julia
Publisher:Public Library of Science
Journal title:PLoS genetics, 2015-12, Vol.11 (12)
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ArticlesPeer ReviewedFull Text
Partial Deletion of Chromosome 8 beta -defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice: e1003826
Author / Creator:Zhou, Yu S ; Webb, Sheila ; Lettice, Laura ; Tardif, Steve ; Kilanowski, Fiona ; Tyrrell, Christine ; MacPherson, Heather ; Semple, Fiona ; Tennant, Peter ; Baker, Tina
Journal title:PLoS genetics, 2013-10, Vol.9 (10)
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ArticlesPeer ReviewedFull Text
Partial Deletion of Chromosome 8 [beta]-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice
Author / Creator:Zhou, Yu ; Webb, Sheila ; Lettice, Laura ; Tardif, Steve ; Kilanowski, Fiona ; Tyrrell, Christine ; Heather MacPherson ; Semple, Fiona ; Tennant, Peter ; Baker, Tina ; Hart, Alan ; Devenney, Paul ; Perry, Paul ; Davey, Tracey ; Barran, Perdita ; Barratt, Chris ; Dorin, Julia
Publisher:Public Library of Science
Journal title:PLoS genetics, 2013-10, Vol.9 (10)
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A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development
Author / Creator:Crane-Smith, Zoe ; Schoenebeck, Jeffrey ; Graham, Katy A ; Devenney, Paul S ; Rose, Lorraine ; Ditzell, Mark ; Klenin, Natasha ; Kurrasch, Deborah M ; Lettice, Laura A ; Hill, Robert
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-10
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Cohesin is required for long-range enhancer action at the Shh locus

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Deletion of CTCF sites in the SHH locus alters enhancer–promoter interactions and leads to acheiropodia

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Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

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Alterations to the remote control of Shh gene expression cause congenital abnormalities

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Use of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development

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Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

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Disruption of a Long-Range Cis-Acting Regulator for Shh Causes Preaxial Polydactyly

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Human β-Defensin 3 [corrected] Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

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Correction: Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

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The Mouse Bagpipe Gene Controls Development of Axial Skeleton, Skull, and Spleen

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Alterations to the remote control of Shh gene expression cause congenital abnormalities

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Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

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Developmentally regulated Shh expression is robust to TAD perturbations

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Human [Beta]-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid: e1005673

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Shh and ZRS enhancer co-localisation is specific to the zone of polarizing activity

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Partial Deletion of Chromosome 8 [beta]-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice: e1003826

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Human [Beta]-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

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Partial Deletion of Chromosome 8 beta -defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice: e1003826

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Partial Deletion of Chromosome 8 [beta]-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

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A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

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