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ArticlesPeer ReviewedFull Text
Synthesis and evaluation of 5, 6-dihydro-8 H -isoquinolino[1, 2- b ]quinazolin-8-one derivatives as novel non-lipogenic ABCA1 up-regulators with inhibitory effects on macrophage-derived foam cell form...
Author / Creator:Yang, Changhuan ; Chen, Lin ; Jiang, Yanmei ; Sun, Demeng ; Hu, Yun
Publisher:England
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2025-12, Vol.40 (1), p.2470310
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ArticlesPeer ReviewedFull Text
LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function
Author / Creator:Waddington, Kirsty E. ; Robinson, George A. ; Rubio-Cuesta, Beatriz ; Chrifi-Alaoui, Eden ; Andreone, Sara ; Poon, Kok-Siong ; Ivanova, Iveta ; Martin-Gutierrez, Lucia ; Owen, Dylan M. ; Jury, Elizabeth C. ; Pineda-Torra, Inés
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (21), p.1-12
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ArticlesPeer ReviewedFull Text
Allicin Decreases Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Umbilical Vein Endothelial Cells through Suppression of Mitochondrial Dysfunction and Activation of Nrf2
Author / Creator:Zhang, Min ; Pan, Huichao ; Xu, Yinjie ; Wang, Xueting ; Qiu, Zhaohui ; Jiang, Li
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2017-01, Vol.41 (6), p.2255-2267
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ArticlesPeer ReviewedFull Text
Network pharmacology of bioactives from Sorghum bicolor with targets related to diabetes mellitus
Author / Creator:Oh, Ki Kwang ; Adnan, Md ; Cho, Dong Ha
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-12, Vol.15 (12), p.e0240873
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ArticlesPeer ReviewedFull Text
The marine‐derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα
Author / Creator:Li, Ting ; Hu, Shu‐Mei ; Pang, Xiao‐Yan ; Wang, Jun‐feng ; Yin, Jia‐Yu ; Li, Fa‐Hui ; Wang, Jin ; Yang, Xiao‐Qian ; Xia, Bin ; Liu, Yong‐Hong ; Song, Wei‐Guo ; Guo, Shou‐Dong
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-03, Vol.24 (6), p.3384-3398
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ArticlesPeer ReviewedFull Text
LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription
Author / Creator:Lin, Zhongjie ; Xia, Shunjie ; Liang, Yuelong ; Ji, Lin ; Pan, Yu ; Jiang, Shi ; Wan, Zhe ; Tao, Liye ; Chen, Jiang ; Lin, Chengping ; Liang, Xiao ; Xu, Junjie ; Cai, Xiujun
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (19), p.8834-8850
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ArticlesPeer ReviewedFull Text
Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve
Author / Creator:Hichor, Mehdi ; Sundaram, Venkat Krishnan ; Eid, Stéphanie A. ; Abdel-Rassoul, Ronza ; Petit, Patrice X. ; Borderie, Didier ; Bastin, Jean ; Eid, Assaad A. ; Manuel, Marin ; Grenier, Julien ; Massaad, Charbel
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.2524-13, Article 2524
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ArticlesPeer ReviewedFull Text
Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain
Author / Creator:Li, Yu-Jiao ; Zhang, Kun ; Sun, Ting ; Wang, Jian ; Guo, Yan-Yan ; Yang, Le ; Yang, Qi ; Li, Yan-Jiao ; Liu, Shui-Bing ; Zhao, Ming-Gao ; Wu, Yu-Mei
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2019-06, Vol.16 (1), p.132-132, Article 132
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ArticlesPeer ReviewedFull Text
Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
Author / Creator:Dresselhaus, Erica ; Duerr, James M ; Vincent, Fabien ; Sylvain, Emily K ; Beyna, Mercedes ; Lanyon, Lorraine F ; LaChapelle, Erik ; Pettersson, Martin ; Bales, Kelly R ; Ramaswamy, Gayathri
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-03, Vol.13 (3), p.e0194661-e0194661
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ArticlesPeer ReviewedFull Text
Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury
Author / Creator:Wang, Zhengyang ; Yang, Xiaoming ; Chen, Liang ; Zhi, Xiuling ; Lu, Hanyu ; Ning, Yanxia ; Yeong, Joe ; Chen, Sifeng ; Yin, Lianhua ; Wang, Xinhong ; Li, Xiaobo
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2017-01, Vol.91 (1), p.271-287
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ArticlesPeer ReviewedFull Text
FOXO1 and LXRα downregulate the apolipoprotein A-I gene expression during hydrogen peroxide-induced oxidative stress in HepG2 cells
Author / Creator:Shavva, Vladimir S. ; Bogomolova, Alexandra M. ; Nikitin, Artemy A. ; Dizhe, Ella B. ; Oleinikova, Galina N. ; Lapikov, Ivan A. ; Tanyanskiy, Dmitry A. ; Perevozchikov, Andrej P. ; Orlov, Sergey V.
Publisher:Dordrecht: Springer
Journal title:Cell stress & chaperones, 2017-01, Vol.22 (1), p.123-134
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ArticlesPeer ReviewedFull Text
Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway
Author / Creator:Wang, Shipeng ; Gu, Xia ; Zhang, Qi ; Zhang, Xiling ; Li, Yilan ; Yao, Yuan ; Yu, Bo ; Zhang, Yao
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2018-01, Vol.46 (1), p.303-313
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Newsletter articlesFull Text
New Severe Acute Respiratory Syndrome Study Results Reported from Azabu University (Cyclic Phthalate Esters As Liver X Receptor Antagonists With Anti-hepatitis C Virus and Anti-severe Acute Respirator...
Publisher:NewsRX LLC
Journal title:Respiratory Therapeutics Week, 2022, p.3309
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Newsletter articlesFull Text
Studies in the Area of Steroid Research Reported from University of Salerno (Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists...
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2015, p.5493
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ArticlesPeer ReviewedFull Text
Liver X receptor antagonist reduces lipid formation and increases glucose metabolism in myotubes from lean, obese and type 2 diabetic individuals
Author / Creator:Kase, E. T ; Thoresen, G. H ; Westerlund, S ; Højlund, K ; Rustan, A. C ; Gaster, M
Publisher:Berlin: Berlin/Heidelberg : Springer-Verlag
Journal title:Diabetologia, 2007-10, Vol.50 (10), p.2171-2180
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Newsletter articlesFull Text
Life Sciences; Study results from GlaxoSmithKline update understanding of life sciences
Publisher:Atlanta: NewsRx
Journal title:Life Science Weekly, 2010, p.3295
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Synthesis and evaluation of 5, 6-dihydro-8 H -isoquinolino[1, 2- b ]quinazolin-8-one derivatives as novel non-lipogenic ABCA1 up-regulators with inhibitory effects on macrophage-derived foam cell form...

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LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function

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Allicin Decreases Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Umbilical Vein Endothelial Cells through Suppression of Mitochondrial Dysfunction and Activation of Nrf2

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Network pharmacology of bioactives from Sorghum bicolor with targets related to diabetes mellitus

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The marine‐derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα

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LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

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Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

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Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain

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Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion

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Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury

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FOXO1 and LXRα downregulate the apolipoprotein A-I gene expression during hydrogen peroxide-induced oxidative stress in HepG2 cells

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Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway

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New Severe Acute Respiratory Syndrome Study Results Reported from Azabu University (Cyclic Phthalate Esters As Liver X Receptor Antagonists With Anti-hepatitis C Virus and Anti-severe Acute Respirator...

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Studies in the Area of Steroid Research Reported from University of Salerno (Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists...

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Liver X receptor antagonist reduces lipid formation and increases glucose metabolism in myotubes from lean, obese and type 2 diabetic individuals

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Life Sciences; Study results from GlaxoSmithKline update understanding of life sciences

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