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124 results for Lymphocytic+Choriomeningitis+-+virology

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ArticlesPeer ReviewedFull Text
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
Author / Creator:Miller, Brian C. ; Sen, Debattama R. ; Al Abosy, Rose ; Bi, Kevin ; Virkud, Yamini V. ; LaFleur, Martin W. ; Yates, Kathleen B. ; Lako, Ana ; Felt, Kristen ; Naik, Girish S. ; Manos, Michael ; Gjini, Evisa ; Kuchroo, Juhi R. ; Ishizuka, Jeffrey J. ; Collier, Jenna L. ; Griffin, Gabriel K. ; Maleri, Seth ; Comstock, Dawn E. ; Weiss, Sarah A. ; Brown, Flavian D. ; Panda, Arpit ; Zimmer, Margaret D. ; Manguso, Robert T. ; Hodi, F. Stephen ; Rodig, Scott J. ; Sharpe, Arlene H. ; Haining, W. Nicholas
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-03, Vol.20 (3), p.326-336
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Effector CD8 T cells dedifferentiate into long-lived memory cells
Author / Creator:Youngblood, Ben ; Hale, J. Scott ; Kissick, Haydn T. ; Ahn, Eunseon ; Xu, Xiaojin ; Wieland, Andreas ; Araki, Koichi ; West, Erin E. ; Ghoneim, Hazem E. ; Fan, Yiping ; Dogra, Pranay ; Davis, Carl W. ; Konieczny, Bogumila T. ; Antia, Rustom ; Cheng, Xiaodong ; Ahmed, Rafi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7685), p.404-409
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Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
Author / Creator:Yao, Chen ; Sun, Hong-Wei ; Lacey, Neal E. ; Ji, Yun ; Moseman, E. Ashley ; Shih, Han-Yu ; Heuston, Elisabeth F. ; Kirby, Martha ; Anderson, Stacie ; Cheng, Jun ; Khan, Omar ; Handon, Robin ; Reilley, Julie ; Fioravanti, Jessica ; Hu, Jinhui ; Gossa, Selamawit ; Wherry, E. John ; Gattinoni, Luca ; McGavern, Dorian B. ; O’Shea, John J. ; Schwartzberg, Pamela L. ; Wu, Tuoqi
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-07, Vol.20 (7), p.890-901
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TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
Author / Creator:Alfei, Francesca ; Kanev, Kristiyan ; Hofmann, Maike ; Wu, Ming ; Ghoneim, Hazem E. ; Roelli, Patrick ; Utzschneider, Daniel T. ; von Hoesslin, Madlaina ; Cullen, Jolie G. ; Fan, Yiping ; Eisenberg, Vasyl ; Wohlleber, Dirk ; Steiger, Katja ; Merkler, Doron ; Delorenzi, Mauro ; Knolle, Percy A. ; Cohen, Cyrille J. ; Thimme, Robert ; Youngblood, Benjamin ; Zehn, Dietmar
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7764), p.265-269
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Structural cells are key regulators of organ-specific immune responses
Author / Creator:Krausgruber, Thomas ; Fortelny, Nikolaus ; Fife-Gernedl, Victoria ; Senekowitsch, Martin ; Schuster, Linda C. ; Lercher, Alexander ; Nemc, Amelie ; Schmidl, Christian ; Rendeiro, André F. ; Bergthaler, Andreas ; Bock, Christoph
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-07, Vol.583 (7815), p.296-302
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Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
Author / Creator:He, Ran ; Hou, Shiyue ; Liu, Cheng ; Zhang, Anli ; Bai, Qiang ; Han, Miao ; Yang, Yu ; Wei, Gang ; Shen, Ting ; Yang, Xinxin ; Xu, Lifan ; Chen, Xiangyu ; Hao, Yaxing ; Wang, Pengcheng ; Zhu, Chuhong ; Ou, Juanjuan ; Liang, Houjie ; Ni, Ting ; Zhang, Xiaoyan ; Zhou, Xinyuan ; Deng, Kai ; Chen, Yaokai ; Luo, Yadong ; Xu, Jianqing ; Qi, Hai ; Wu, Yuzhang ; Ye, Lilin
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-09, Vol.537 (7620), p.412-416
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Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade
Author / Creator:Jadhav, Rohit R. ; Im, Se Jin ; Hu, Bin ; Hashimoto, Masao ; Li, Peng ; Lin, Jian-Xin ; Leonard, Warren J. ; Greenleaf, William J. ; Ahmed, Rafi ; Goronzy, Jorg J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (28), p.14113-14118
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ArticlesPeer ReviewedFull Text
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
Author / Creator:Doedens, Andrew L ; Phan, Anthony T ; Stradner, Martin H ; Fujimoto, Jessica K ; Nguyen, Jessica V ; Yang, Edward ; Johnson, Randall S ; Goldrath, Ananda W
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2013-11, Vol.14 (11), p.1173-1182
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ArticlesPeer ReviewedFull Text
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity
Author / Creator:Gautam, Sanjivan ; Fioravanti, Jessica ; Zhu, Wei ; Le Gall, John B. ; Brohawn, Philip ; Lacey, Neal E. ; Hu, Jinhui ; Hocker, James D. ; Hawk, Nga Voong ; Kapoor, Veena ; Telford, William G. ; Gurusamy, Devikala ; Yu, Zhiya ; Bhandoola, Avinash ; Xue, Hai-Hui ; Roychoudhuri, Rahul ; Higgs, Brandon W. ; Restifo, Nicholas P. ; Bender, Timothy P. ; Ji, Yun ; Gattinoni, Luca
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-03, Vol.20 (3), p.337-349
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ArticlesPeer ReviewedFull Text
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
Author / Creator:Jin, Hyun-Tak ; Anderson, Ana C. ; Tan, Wendy G. ; West, Erin E. ; Ha, Sang-Jun ; Araki, Koichi ; Freeman, Gordon J. ; Kuchroo, Vijay K. ; Ahmed, Rafi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (33), p.14733-14738
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ArticlesPeer ReviewedFull Text
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
Author / Creator:Laidlaw, Brian J ; Cui, Weiguo ; Amezquita, Robert A ; Gray, Simon M ; Guan, Tianxia ; Lu, Yisi ; Kobayashi, Yasushi ; Flavell, Richard A ; Kleinstein, Steven H ; Craft, Joe ; Kaech, Susan M
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-08, Vol.16 (8), p.871-879
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ArticlesPeer ReviewedFull Text
FXR mediates T cell-intrinsic responses to reduced feeding during infection
Author / Creator:Campbell, Clarissa ; Marchildon, Francois ; Michaels, Anthony J. ; Takemoto, Naofumi ; van der Veeken, Joris ; Schizas, Michail ; Pritykin, Yuri ; Leslie, Christina S. ; Intlekofer, Andrew M. ; Cohen, Paul ; Rudensky, Alexander Y.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (52), p.33446-33454
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ArticlesPeer ReviewedFull Text
Natural killer cells act as rheostats modulating antiviral T cells
Author / Creator:Waggoner, Stephen N. ; Cornberg, Markus ; Selin, Liisa K. ; Welsh, Raymond M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-01, Vol.481 (7381), p.394-398
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A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system
Author / Creator:LaFleur, Martin W. ; Nguyen, Thao H. ; Coxe, Matthew A. ; Yates, Kathleen B. ; Trombley, Justin D. ; Weiss, Sarah A. ; Brown, Flavian D. ; Gillis, Jacob E. ; Coxe, Daniel J. ; Doench, John G. ; Haining, W. Nicholas ; Sharpe, Arlene H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1668-1668, Article 1668
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ArticlesPeer ReviewedFull Text
The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection
Author / Creator:Kotzin, Jonathan J. ; Iseka, Fany ; Wright, Jasmine ; Basavappa, Megha G. ; Clark, Megan L. ; Ali, Mohammed-Alkhatim ; Robertson, Tanner F. ; Mowel, Walter K. ; Joannas, Leonel ; Neal, Vanessa D. ; Spencer, Sean P. ; Syrett, Camille M. ; Anguera, Montserrat C. ; Williams, Adam ; Wherry, E. John ; Henao-Mejia, Jorge
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (24), p.11916-11925
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ArticlesPeer ReviewedFull Text
T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion
Author / Creator:Utzschneider, Daniel T ; Legat, Amandine ; Fuertes Marraco, Silvia A ; Carrié, Lucie ; Luescher, Immanuel ; Speiser, Daniel E ; Zehn, Dietmar
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2013-06, Vol.14 (6), p.603-610
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ArticlesPeer ReviewedFull Text
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation
Author / Creator:Muri, Jonathan ; Heer, Sebastian ; Matsushita, Mai ; Pohlmeier, Lea ; Tortola, Luigi ; Fuhrer, Tobias ; Conrad, Marcus ; Zamboni, Nicola ; Kisielow, Jan ; Kopf, Manfred
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.1851-16, Article 1851
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Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues
Author / Creator:Ali, Ayad ; Canaday, Laura M ; Feldman, H Alex ; Cevik, Hilal ; Moran, Michael T ; Rajaram, Sanjeeth ; Lakes, Nora ; Tuazon, Jasmine A ; Seelamneni, Harsha ; Krishnamurthy, Durga ; Blass, Eryn ; Barouch, Dan H ; Waggoner, Stephen N
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-09, Vol.131 (18)
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ArticlesPeer ReviewedFull Text
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection
Author / Creator:Huang, Li-Rung ; Wohlleber, Dirk ; Reisinger, Florian ; Jenne, Craig N ; Cheng, Ru-Lin ; Abdullah, Zeinab ; Schildberg, Frank A ; Odenthal, Margarete ; Dienes, Hans-Peter ; van Rooijen, Nico ; Schmitt, Edgar ; Garbi, Natalio ; Croft, Michael ; Kurts, Christian ; Kubes, Paul ; Protzer, Ulrike ; Heikenwalder, Mathias ; Knolle, Percy A
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2013-06, Vol.14 (6), p.574-583
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ArticlesPeer ReviewedFull Text
Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection
Author / Creator:Chen, Jonathan H ; Perry, Curtis J ; Tsui, Yao-Chen ; Staron, Matthew M ; Parish, Ian A ; Dominguez, Claudia X ; Rosenberg, Daniel W ; Kaech, Susan M
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-04, Vol.21 (4), p.327-334
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Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

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Effector CD8 T cells dedifferentiate into long-lived memory cells

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Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

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TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

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Structural cells are key regulators of organ-specific immune responses

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Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection

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Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade

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Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen

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The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

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Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells

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FXR mediates T cell-intrinsic responses to reduced feeding during infection

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Natural killer cells act as rheostats modulating antiviral T cells

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A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system

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The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection

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T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion

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The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

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Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues

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Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

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Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection

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