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ArticlesPeer ReviewedFull Text
MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family
Author / Creator:Beverly, L J ; Varmus, H E
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2009-03, Vol.28 (9), p.1274-1279
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Minocycline suppresses interleukine-6, its receptor system and signaling pathways and impairs migration, invasion and adhesion capacity of ovarian cancer cells: in vitro and in vivo studies
Author / Creator:Ataie-Kachoie, Parvin ; Morris, David L ; Pourgholami, Mohammad H
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e60817
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ArticlesPeer ReviewedFull Text
Altering chemosensitivity by modulating translation elongation
Author / Creator:Robert, Francis ; Carrier, Marilyn ; Rawe, Svea ; Chen, Samuel ; Lowe, Scott ; Pelletier, Jerry
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-05, Vol.4 (5), p.e5428-e5428
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Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis
Author / Creator:XIA, L ; WURMBACH, E ; WAXMAN, S ; JING, Y
Publisher:London: Nature Publishing
Journal title:Leukemia, 2006-06, Vol.20 (6), p.1009-1016
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ArticlesFull Text
Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways
Author / Creator:Guo, Zhi Lan ; Li, Jing Zhe ; Ma, Yan Yan ; Qian, Dan ; Zhong, Ju Ying ; Jin, Meng Meng ; Huang, Peng ; Che, Lu Yang ; Pan, Bing ; Wang, Yi ; Sun, Zhen Xiao ; Liu, Chang Zhen
Publisher:England: BioMed Central Ltd
Journal title:BMC cell biology, 2018-12, Vol.19 (1), p.29-29, Article 29
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ArticlesPeer ReviewedFull Text
mir-29 regulates Mcl-1 protein expression and apoptosis
Author / Creator:Mott, J L ; Kobayashi, S ; Bronk, S F ; Gores, G J
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2007-09, Vol.26 (42), p.6133-6140
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Mcl-1 Protein and Viral Infections: A Narrative Review
Author / Creator:Wyżewski, Zbigniew ; Stępkowska, Justyna ; Kobylińska, Aleksandra Maria ; Mielcarska, Adriana ; Mielcarska, Matylda Barbara
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-01, Vol.25 (2), p.1138
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Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells
Author / Creator:Slomp, Anne ; Moesbergen, Laura M. ; Eldering, Eric ; Kersten, Marie José ; Minnema, Monique C. ; Peperzak, Victor
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-03, Vol.12 (3), p.229-229, Article 229
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Elevated USP9X drives early-to-late-stage oral tumorigenesis via stabilisation of anti-apoptotic MCL-1 protein and impacts outcome in oral cancers
Author / Creator:Sulkshane, Prasad ; Pawar, Sagar N. ; Waghole, Rohit ; Pawar, Sushil S. ; Rajput, Priyanka ; Uthale, Abhay ; Oak, Swapnil ; Kalkar, Prajakta ; Wani, Harshada ; Patil, Rahul ; Nair, Sudhir ; Rane, Pallavi ; Teni, Tanuja
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2021-08, Vol.125 (4), p.547-560
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MDM2 drives resistance to Osimertinib by contextually disrupting FBW7-mediated destruction of MCL-1 protein in EGFR mutant NSCLC
Author / Creator:Liu, Jiaxin ; Wei, Lingyun ; Miao, Qing ; Zhan, Sutong ; Chen, Peilin ; Liu, Wei ; Cao, Liang ; Wang, Dong ; Liu, Hongbing ; Yin, Jie ; Song, Yong ; Ye, Mingxiang ; Lv, Tangfeng
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2024-11, Vol.43 (1), p.302-17, Article 302
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Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability
Author / Creator:Wu, D-W ; Chen, C-Y ; Chu, C-L ; Lee, H
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2016-02, Vol.35 (5), p.621-630
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By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737
Author / Creator:Tailler, Maximilien ; Lindqvist, Lisa M. ; Gibson, Leonie ; Adams, Jerry M.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-09, Vol.26 (9), p.1766-1781
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The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak
Author / Creator:Cao, Xiaobo ; Yap, Jeremy L ; Newell-Rogers, M Karen ; Peddaboina, Chander ; Jiang, Weihua ; Papaconstantinou, Harry T ; Jupitor, Dan ; Rai, Arun ; Jung, Kwan-Young ; Tubin, Richard P ; Yu, Wenbo ; Vanommeslaeghe, Kenno ; Wilder, Paul T ; MacKerell, Jr, Alexander D ; Fletcher, Steven ; Smythe, Roy W
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2013-05, Vol.12 (1), p.42-42, Article 42
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XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis
Author / Creator:Zhu, Zhi-Chuan ; Liu, Ji-Wei ; Yang, Can ; Zhao, Miao ; Xiong, Zhi-Qi
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-05, Vol.10 (6), p.395, Article 395
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Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia
Author / Creator:Zhou, Fang-jiao ; Zeng, Chen-xing ; Kuang, Wei ; Cheng, Cong ; Liu, Hong-cai ; Yan, Xue-ying ; Chen, Xiao-ping ; Zhou, Gan ; Cao, Shan
Publisher:Wyoming: Ivyspring International Publisher Pty Ltd
Journal title:Journal of Cancer, 2021-01, Vol.12 (22), p.6727-6739
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Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibiti...
Author / Creator:Seo, Bo Ram ; Min, Kyoung-Jin ; Cho, Il Je ; Kim, Sang Chan ; Kwon, Taeg Kyu
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-04, Vol.9 (4), p.e95588
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A Structure-Guided Designed Small Molecule Is an Anticancer Agent and Inhibits the Apoptosis-Related MCL-1 Protein
Author / Creator:Machado, Ingrid V. ; Naves, Luiz F. N. ; Custodio, Jean M. F. ; Vidal, Hérika D. A. ; Queiroz, Jaqueline E. ; Oliver, Allen G. ; Borba, Joyce V. B. ; Neves, Bruno J. ; Brito, Lucas M. ; Pessoa, Claudia ; Napolitano, Hamilton B. ; Aquino, Gilberto L. B. de
Publisher:Merced: MDPI AG
Journal title:Biophysica, 2023-09, Vol.3 (3), p.446-462
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COMPONENTS OF ANTITUMOR EXTRACT OF GRATIOLA OFFICINALIS LEAD TO TUMOR CELL DEATH BY APOPTOSIS DUE TO NEGATIVE REGULATION OF MCL-1 PROTEIN
Author / Creator:Polukonova, N V ; Demin, A G ; Polukonova, A V
Publisher:Moscow: Russian New University
Journal title:Cardiometry, 2023-11 (29), p.28-28
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HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade
Author / Creator:Hu, Liang ; Chen, Lei ; Yang, GuangZhen ; Li, Liang ; Sun, HanYong ; Chang, Yanxin ; Tu, QianQian ; Wu, MengChao ; Wang, HongYang
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2011-04, Vol.10 (1), p.43-43, Article 43
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Proteasome inhibitors induce apoptosis in human lung cancer cells through a positive feedback mechanism and the subsequent Mcl-1 protein cleavage
Author / Creator:Yuan, B-Z ; Chapman, J ; Reynolds, S H
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2009-10, Vol.28 (43), p.3775-3786
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MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family

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Minocycline suppresses interleukine-6, its receptor system and signaling pathways and impairs migration, invasion and adhesion capacity of ovarian cancer cells: in vitro and in vivo studies

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Altering chemosensitivity by modulating translation elongation

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Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis

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Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways

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mir-29 regulates Mcl-1 protein expression and apoptosis

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Mcl-1 Protein and Viral Infections: A Narrative Review

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Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells

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Elevated USP9X drives early-to-late-stage oral tumorigenesis via stabilisation of anti-apoptotic MCL-1 protein and impacts outcome in oral cancers

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MDM2 drives resistance to Osimertinib by contextually disrupting FBW7-mediated destruction of MCL-1 protein in EGFR mutant NSCLC

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Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability

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By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737

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The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak

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XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis

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Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia

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Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibiti...

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A Structure-Guided Designed Small Molecule Is an Anticancer Agent and Inhibits the Apoptosis-Related MCL-1 Protein

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COMPONENTS OF ANTITUMOR EXTRACT OF GRATIOLA OFFICINALIS LEAD TO TUMOR CELL DEATH BY APOPTOSIS DUE TO NEGATIVE REGULATION OF MCL-1 PROTEIN

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HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade

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Proteasome inhibitors induce apoptosis in human lung cancer cells through a positive feedback mechanism and the subsequent Mcl-1 protein cleavage

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