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102 results for Nucleus+Pulposus+-+cytology

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p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle
Author / Creator:Che, Hui ; Li, Jie ; Li, You ; Ma, Cheng ; Liu, Huan ; Qin, Jingyi ; Dong, Jianghui ; Zhang, Zhen ; Xian, Cory J ; Miao, Dengshun ; Wang, Liping ; Ren, Yongxin
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2020-03, Vol.9
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The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration
Author / Creator:Dudek, Michal ; Yang, Nan ; Ruckshanthi, Jayalath PD ; Williams, Jack ; Borysiewicz, Elzbieta ; Wang, Ping ; Adamson, Antony ; Li, Jian ; Bateman, John F ; White, Michael R ; Boot-Handford, Raymond P ; Hoyland, Judith A ; Meng, Qing-Jun
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2017-03, Vol.76 (3), p.576-584
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Chondrocyte‐like nested cells in the aged intervertebral disc are late‐stage nucleus pulposus cells
Author / Creator:Mohanty, Sarthak ; Pinelli, Robert ; Pricop, Paul ; Albert, Todd J. ; Dahia, Chitra Lekha
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-10, Vol.18 (5), p.e13006-n/a
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Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells
Author / Creator:Lu, Kang ; Li, Hai-Yin ; Yang, Kuang ; Wu, Jun-Long ; Cai, Xiao-Wei ; Zhou, Yue ; Li, Chang-Qing
Publisher:England: BioMed Central
Journal title:Stem cell research & therapy, 2017-05, Vol.8 (1), p.108-108, Article 108
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Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy
Author / Creator:Xu, Wen-Ning ; Zheng, Huo-Liang ; Yang, Run-Ze ; Liu, Tao ; Yu, Wei ; Zheng, Xin-Feng ; Li, Bo ; Jiang, Sheng-Dan ; Jiang, Lei-Sheng
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2019, 51(0), , pp.1-16
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TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivo
Author / Creator:Wang, Kun ; Yao, Dengbo ; Li, Yuxi ; Li, Ming ; Zeng, Weike ; Liao, Zhuangyao ; Chen, Engming ; Lu, Shixin ; Su, Kaihui ; Che, Zhen ; Liang, Yuwei ; Wang, Peng ; Huang, Lin
Publisher:England: BioMed Central
Journal title:Arthritis research & therapy, 2023-03, Vol.25 (1), p.45-45, Article 45
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Exosomes Derived from Bone Mesenchymal Stem Cells Alleviate Compression-Induced Nucleus Pulposus Cell Apoptosis by Inhibiting Oxidative Stress
Author / Creator:Hu, Yiqiang ; Tao, Ranyang ; Wang, Linfang ; Chen, Lang ; Lin, Ze ; Panayi, Adriana C. ; Xue, Hang ; Li, Hui ; Xiong, Liming ; Liu, Guohui
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.2310025-2310025
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Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway
Author / Creator:Lu, Lin ; Hu, Jialang ; Wu, Qipeng ; An, Ying ; Cui, Wei ; Wang, Junwen ; Ye, Zhewei
Publisher:Athens: Spandidos Publications UK Ltd
Journal title:International journal of molecular medicine, 2019-04, Vol.43 (4), p.1679-1686
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Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage
Author / Creator:Gao, Jinlou ; Zhang, Qingyun ; Song, Lin
Publisher:England: Portland Press Ltd
Journal title:Bioscience reports, 2018-08, Vol.38 (4)
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miR‐640 aggravates intervertebral disc degeneration via NF‐κB and WNT signalling pathway
Author / Creator:Dong, Wengang ; Liu, Jun ; Lv, Yang ; Wang, Fei ; Liu, Tao ; Sun, Siguo ; Liao, Bo ; Shu, Zhen ; Qian, Jixian
Publisher:England: John Wiley & Sons, Inc
Journal title:Cell proliferation, 2019-09, Vol.52 (5), p.e12664-n/a
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Differential expression of p38 MAPK α, β, γ, δ isoforms in nucleus pulposus modulates macrophage polarization in intervertebral disc degeneration
Author / Creator:Yang, Chen ; Cao, Peng ; Gao, Yang ; Wu, Ming ; Lin, Yun ; Tian, Ye ; Yuan, Wen
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-02, Vol.6 (1), p.22182-22182, Article 22182
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MiRNA Let-7i-5p-Contained Small Extracellular Vesicles from Macrophages Induce Nucleus Pulposus Cell Senescence via Targeting LIN28A
Author / Creator:Zhang, Shuo ; Yan, Miaoheng ; Lv, Xiao ; Wang, Peng ; Liu, Weijian ; Hu, Binwu ; Chen, Songfeng ; Shao, Zengwu
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:International journal of nanomedicine, 2025-01, Vol.20, p.2163-2179
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Adipose Tissue-Derived Exosome Maintains Metabolic Balance of Extracellular Matrix in Rat Nucleus Pulposus Cells
Author / Creator:Zhao, Ruoyu ; Ma, Lei ; Li, Joan ; Liu, Sen ; Yang, Dalong ; Liu, Guobin ; Yang, Sidong
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:International journal of nanomedicine, 2025-01, Vol.20, p.2411-2425
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Assessment of Tie2-Rejuvenated Nucleus Pulposus Cell Transplants from Young and Old Patient Sources Demonstrates That Age Still Matters
Author / Creator:Otani, Yuto ; Schol, Jordy ; Sakai, Daisuke ; Nakamura, Yoshihiko ; Sako, Kosuke ; Warita, Takayuki ; Tamagawa, Shota ; Ambrosio, Luca ; Munesada, Daiki ; Ogasawara, Shota ; Matsushita, Erika ; Kawachi, Asami ; Naiki, Mitsuru ; Sato, Masato ; Watanabe, Masahiko
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (15), p.8335
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Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells
Author / Creator:Tu, Ji ; Li, Wentian ; Zhang, Yukun ; Wu, Xinghuo ; Song, Yu ; Kang, Liang ; Liu, Wei ; Wang, Kun ; Li, Shuai ; Hua, Wenbin ; Yang, Cao
Publisher:New York: Springer US
Journal title:Inflammation, 2017-06, Vol.40 (3), p.725-734
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Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Author / Creator:Zhang, Hao ; Zhang, Di ; Wang, Hui ; Liu, Yilei ; Ding, Wenyuan ; Fan, Guangpu ; Meng, Xianzhong
Publisher:Greece: D.A. Spandidos
Journal title:Molecular medicine reports, 2025-05, Vol.31 (5), p.1-11
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Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets
Author / Creator:Rajasekaran, Shanmuganathan ; Tangavel, Chitraa ; Djuric, Niek ; Raveendran, Muthurajan ; Soundararajan, Dilip Chand Raja ; Nayagam, Sharon Miracle ; Matchado, Monica Steffi ; Anand, K. S. Sri Vijay
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.15684-15684, Article 15684
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Umbilical cord mesenchymal stem cell conditioned medium restored the expression of collagen II and aggrecan in nucleus pulposus mesenchymal stem cells exposed to high glucose
Author / Creator:Qi, Lei ; Wang, Ran ; Shi, Qing ; Yuan, Ming ; Jin, Min ; Li, Dong
Publisher:Tokyo: Springer Japan
Journal title:Journal of bone and mineral metabolism, 2019-05, Vol.37 (3), p.455-466
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Down-Regulation of microRNA-30d Alleviates Intervertebral Disc Degeneration Through the Promotion of FOXO3 and Suppression of CXCL10
Author / Creator:Xia, Peng ; Gao, Xu ; Li, Fang ; Shao, Liwei ; Sun, Yifu
Publisher:New York: Springer US
Journal title:Calcified tissue international, 2021-02, Vol.108 (2), p.252-264
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RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration
Author / Creator:Shao, Zhenxuan ; Ni, Libin ; Hu, Sunli ; Xu, Tianzhen ; Meftah, Zaher ; Yu, Zupo ; Tian, Naifeng ; Wu, Yaosen ; Sun, Liaojun ; Wu, Aimin ; Pan, Zongyou ; Chen, Linwei ; Gao, Weiyang ; Zhou, Yifei ; Zhang, Xiaolei ; Wang, Xiangyang
Publisher:England: John Wiley & Sons, Inc
Journal title:Cell proliferation, 2021-02, Vol.54 (2), p.e12975-n/a
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p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle

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The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration

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Chondrocyte‐like nested cells in the aged intervertebral disc are late‐stage nucleus pulposus cells

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Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

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Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy

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TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivo

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Exosomes Derived from Bone Mesenchymal Stem Cells Alleviate Compression-Induced Nucleus Pulposus Cell Apoptosis by Inhibiting Oxidative Stress

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Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway

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Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage

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miR‐640 aggravates intervertebral disc degeneration via NF‐κB and WNT signalling pathway

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Differential expression of p38 MAPK α, β, γ, δ isoforms in nucleus pulposus modulates macrophage polarization in intervertebral disc degeneration

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MiRNA Let-7i-5p-Contained Small Extracellular Vesicles from Macrophages Induce Nucleus Pulposus Cell Senescence via Targeting LIN28A

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Adipose Tissue-Derived Exosome Maintains Metabolic Balance of Extracellular Matrix in Rat Nucleus Pulposus Cells

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Assessment of Tie2-Rejuvenated Nucleus Pulposus Cell Transplants from Young and Old Patient Sources Demonstrates That Age Still Matters

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Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells

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Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells

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Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets

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Umbilical cord mesenchymal stem cell conditioned medium restored the expression of collagen II and aggrecan in nucleus pulposus mesenchymal stem cells exposed to high glucose

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Down-Regulation of microRNA-30d Alleviates Intervertebral Disc Degeneration Through the Promotion of FOXO3 and Suppression of CXCL10

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RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration

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