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291 results for Phagocytosis+-+genetics

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A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states
Author / Creator:Dräger, Nina M. ; Sattler, Sydney M. ; Huang, Cindy Tzu-Ling ; Teter, Olivia M. ; Leng, Kun ; Hashemi, Sayed Hadi ; Hong, Jason ; Aviles, Giovanni ; Clelland, Claire D. ; Zhan, Lihong ; Udeochu, Joe C. ; Kodama, Lay ; Singleton, Andrew B. ; Nalls, Mike A. ; Ichida, Justin ; Ward, Michael E. ; Faghri, Faraz ; Gan, Li ; Kampmann, Martin
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2022-09, Vol.25 (9), p.1149-1162
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Aging disrupts circadian gene regulation and function in macrophages
Author / Creator:Blacher, Eran ; Tsai, Connie ; Litichevskiy, Lev ; Shipony, Zohar ; Iweka, Chinyere Agbaegbu ; Schneider, Kai Markus ; Chuluun, Bayarsaikhan ; Heller, H. Craig ; Menon, Vilas ; Thaiss, Christoph A. ; Andreasson, Katrin I.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-02, Vol.23 (2), p.229-236
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Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release
Author / Creator:Morioka, Sho ; Perry, Justin S. A. ; Raymond, Michael H. ; Medina, Christopher B. ; Zhu, Yunlu ; Zhao, Liyang ; Serbulea, Vlad ; Onengut-Gumuscu, Suna ; Leitinger, Norbert ; Kucenas, Sarah ; Rathmell, Jeffrey C. ; Makowski, Liza ; Ravichandran, Kodi S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-11, Vol.563 (7733), p.714-718
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CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
Author / Creator:Pluvinage, John V. ; Haney, Michael S. ; Smith, Benjamin A. H. ; Sun, Jerry ; Iram, Tal ; Bonanno, Liana ; Li, Lulin ; Lee, Davis P. ; Morgens, David W. ; Yang, Andrew C. ; Shuken, Steven R. ; Gate, David ; Scott, Madeleine ; Khatri, Purvesh ; Luo, Jian ; Bertozzi, Carolyn R. ; Bassik, Michael C. ; Wyss-Coray, Tony
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-04, Vol.568 (7751), p.187-192
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TREM2 sustains microglial expansion during aging and response to demyelination
Author / Creator:Poliani, Pietro Luigi ; Wang, Yaming ; Fontana, Elena ; Robinette, Michelle L. ; Yamanishi, Yoshinori ; Gilfillan, Susan ; Colonna, Marco
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-05, Vol.125 (5), p.2161-2170
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Emerging phagocytosis checkpoints in cancer immunotherapy
Author / Creator:Liu, Yu’e ; Wang, Yanjin ; Yang, Yanrong ; Weng, Linjun ; Wu, Qi ; Zhang, Jin ; Zhao, Pengcheng ; Fang, Lan ; Shi, Yufeng ; Wang, Ping
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2023-03, Vol.8 (1), p.104-104, Article 104
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TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
Author / Creator:Ciesielska, Anna ; Matyjek, Marta ; Kwiatkowska, Katarzyna
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2021-02, Vol.78 (4), p.1233-1261
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Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2
Author / Creator:Luo, Xiang ; Gong, Hai-Biao ; Gao, Hua-Ying ; Wu, Yan-Ping ; Sun, Wan-Yang ; Li, Zheng-Qiu ; Wang, Guan ; Liu, Bo ; Liang, Lei ; Kurihara, Hiroshi ; Duan, Wen-Jun ; Li, Yi-Fang ; He, Rong-Rong
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2021-06, Vol.28 (6), p.1971-1989
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Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways
Author / Creator:Qian, Mingyu ; Wang, Shaobo ; Guo, Xiaofan ; Wang, Jian ; Zhang, Zongpu ; Qiu, Wei ; Gao, Xiao ; Chen, Zihang ; Xu, Jianye ; Zhao, Rongrong ; Xue, Hao ; Li, Gang
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-01, Vol.39 (2), p.428-442
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Stroke subtype-dependent synapse elimination by reactive gliosis in mice
Author / Creator:Shi, Xiaojing ; Luo, Longlong ; Wang, Jixian ; Shen, Hui ; Li, Yongfang ; Mamtilahun, Muyassar ; Liu, Chang ; Shi, Rubing ; Lee, Joon-Hyuk ; Tian, Hengli ; Zhang, Zhijun ; Wang, Yongting ; Chung, Won-Suk ; Tang, Yaohui ; Yang, Guo-Yuan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6943-6943, Article 6943
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Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation
Author / Creator:Germic, Nina ; Frangez, Ziva ; Yousefi, Shida ; Simon, Hans-Uwe
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-04, Vol.26 (4), p.715-727
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Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment
Author / Creator:Iida, Noriho ; Dzutsev, Amiran ; Stewart, C. Andrew ; Smith, Loretta ; Bouladoux, Nicolas ; Weingarten, Rebecca A. ; Molina, Daniel A. ; Salcedo, Rosalba ; Back, Timothy ; Cramer, Sarah ; Dai, Ren-Ming ; Kiu, Hiu ; Cardone, Marco ; Naik, Shruti ; Patri, Anil K. ; Wang, Ena ; Marincola, Francesco M. ; Frank, Karen M. ; Belkaid, Yasmine ; Trinchieri, Giorgio ; Goldszmid, Romina S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6161), p.967-970
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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
Author / Creator:Heneka, Michael T. ; Kummer, Markus P. ; Stutz, Andrea ; Delekate, Andrea ; Schwartz, Stephanie ; Vieira-Saecker, Ana ; Griep, Angelika ; Axt, Daisy ; Remus, Anita ; Tzeng, Te-Chen ; Gelpi, Ellen ; Halle, Annett ; Korte, Martin ; Latz, Eicke ; Golenbock, Douglas T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-01, Vol.493 (7434), p.674-678
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The ligation between ERMAP, galectin-9 and dectin-2 promotes Kupffer cell phagocytosis and antitumor immunity
Author / Creator:Li, Jie ; Liu, Xiao-gang ; Ge, Rui-liang ; Yin, Yu-peng ; Liu, Yong-da ; Lu, Wan-peng ; Huang, Mei ; He, Xue-ying ; Wang, Jinghan ; Cai, Guoxiang ; Sun, Shu-han ; Yuan, Ji-hang
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-11, Vol.24 (11), p.1813-1824
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Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
Author / Creator:Haney, Michael S. ; Bohlen, Christopher J. ; Morgens, David W. ; Ousey, James A. ; Barkal, Amira A. ; Tsui, C. Kimberly ; Ego, Braeden K. ; Levin, Roni ; Kamber, Roarke A. ; Collins, Hannah ; Tucker, Andrew ; Li, Amy ; Vorselen, Daan ; Labitigan, Lorenzo ; Crane, Emily ; Boyle, Evan ; Jiang, Lihua ; Chan, Joanne ; Rincón, Esther ; Greenleaf, William J. ; Li, Billy ; Snyder, Michael P. ; Weissman, Irving L. ; Theriot, Julie A. ; Collins, Sean R. ; Barres, Ben A. ; Bassik, Michael C.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2018-12, Vol.50 (12), p.1716-1727
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LncRNA MIAT sponges miR-149-5p to inhibit efferocytosis in advanced atherosclerosis through CD47 upregulation
Author / Creator:Ye, Zi-ming ; Yang, Shuai ; Xia, Yuan-peng ; Hu, Rui-ting ; Chen, Shengcai ; Li, Bo-wei ; Chen, Shao-li ; Luo, Xue-ying ; Mao, Ling ; Li, Yanan ; Jin, Huijuan ; Qin, Chao ; Hu, Bo
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-02, Vol.10 (2), p.138-138, Article 138
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Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia
Author / Creator:Colombo, Alessio ; Dinkel, Lina ; Müller, Stephan A. ; Sebastian Monasor, Laura ; Schifferer, Martina ; Cantuti-Castelvetri, Ludovico ; König, Jasmin ; Vidatic, Lea ; Bremova-Ertl, Tatiana ; Lieberman, Andrew P. ; Hecimovic, Silva ; Simons, Mikael ; Lichtenthaler, Stefan F. ; Strupp, Michael ; Schneider, Susanne A. ; Tahirovic, Sabina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1158-1158, Article 1158
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Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells
Author / Creator:Bian, Zhen ; Shi, Lei ; Guo, Ya-Lan ; Lv, Zhiyuan ; Tang, Cong ; Niu, Shuo ; Tremblay, Alexandra ; Venkataramani, Mahathi ; Culpepper, Courtney ; Li, Limin ; Zhou, Zhen ; Mansour, Ahmed ; Zhang, Yongliang ; Gewirtz, Andrew ; Kidder, Koby ; Zen, Ke ; Liu, Yuan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (37), p.E5434-E5443
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Peroxisomes in Immune Response and Inflammation
Author / Creator:Di Cara, Francesca ; Andreoletti, Pierre ; Trompier, Doriane ; Vejux, Anne ; Bülow, Margret H. ; Sellin, Julia ; Lizard, Gérard ; Cherkaoui-Malki, Mustapha ; Savary, Stéphane
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-08, Vol.20 (16), p.3877
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Cellular senescence contributes to age‐dependent changes in circulating extracellular vesicle cargo and function
Author / Creator:Alibhai, Faisal J. ; Lim, Fievel ; Yeganeh, Azadeh ; DiStefano, Peter V. ; Binesh‐Marvasti, Tina ; Belfiore, Alyssa ; Wlodarek, Lukasz ; Gustafson, Dakota ; Millar, Sean ; Li, Shu‐Hong ; Weisel, Richard D. ; Fish, Jason E. ; Li, Ren‐Ke
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2020-03, Vol.19 (3), p.e13103-n/a
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A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states

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Aging disrupts circadian gene regulation and function in macrophages

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Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

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CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

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TREM2 sustains microglial expansion during aging and response to demyelination

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Emerging phagocytosis checkpoints in cancer immunotherapy

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TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

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Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2

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Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways

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Stroke subtype-dependent synapse elimination by reactive gliosis in mice

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Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation

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Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

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The ligation between ERMAP, galectin-9 and dectin-2 promotes Kupffer cell phagocytosis and antitumor immunity

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Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

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LncRNA MIAT sponges miR-149-5p to inhibit efferocytosis in advanced atherosclerosis through CD47 upregulation

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Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

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Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells

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Peroxisomes in Immune Response and Inflammation

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Cellular senescence contributes to age‐dependent changes in circulating extracellular vesicle cargo and function

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