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51 results for Tankyrases+-+antagonists+

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ArticlesPeer ReviewedFull Text
Wnt/beta-catenin pathway: modulating anticancer immune response
Author / Creator:Pai, Sachin Gopalkrishna ; Carneiro, Benedito A. ; Mota, Jose Mauricio ; Costa, Ricardo ; Leite, Caio Abner ; Barroso-Sousa, Romualdo ; Kaplan, Jason Benjamin ; Chae, Young Kwang ; Giles, Francis Joseph
Publisher:England: BioMed Central
Journal title:Journal of hematology and oncology, 2017-05, Vol.10 (1), p.101-101, Article 101
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Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Author / Creator:Wahlberg, Elisabet ; Karlberg, Tobias ; Kouznetsova, Ekaterina ; Markova, Natalia ; Macchiarulo, Antonio ; Thorsell, Ann-Gerd ; Pol, Ewa ; Frostell, Åsa ; Ekblad, Torun ; Öncü, Delal ; Kull, Björn ; Robertson, Graeme Michael ; Pellicciari, Roberto ; Schüler, Herwig ; Weigelt, Johan
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2012-03, Vol.30 (3), p.283-288
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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Author / Creator:Huang, Shih-Min A. ; Mishina, Yuji M. ; Liu, Shanming ; Cheung, Atwood ; Stegmeier, Frank ; Michaud, Gregory A. ; Charlat, Olga ; Wiellette, Elizabeth ; Zhang, Yue ; Wiessner, Stephanie ; Hild, Marc ; Shi, Xiaoying ; Wilson, Christopher J. ; Mickanin, Craig ; Myer, Vic ; Fazal, Aleem ; Tomlinson, Ronald ; Serluca, Fabrizio ; Shao, Wenlin ; Cheng, Hong ; Shultz, Michael ; Rau, Christina ; Schirle, Markus ; Schlegl, Judith ; Ghidelli, Sonja ; Fawell, Stephen ; Lu, Chris ; Curtis, Daniel ; Kirschner, Marc W. ; Lengauer, Christoph ; Finan, Peter M. ; Tallarico, John A. ; Bouwmeester, Tewis ; Porter, Jeffery A. ; Bauer, Andreas ; Cong, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-10, Vol.461 (7264), p.614-620
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Tankyrase-targeted therapeutics: expanding opportunities in the PARP family
Author / Creator:Riffell, Jenna L. ; Lord, Christopher J. ; Ashworth, Alan
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2012-12, Vol.11 (12), p.923-936
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Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling
Author / Creator:Li, Nan ; Wang, Yifan ; Neri, Shinya ; Zhen, Yuanli ; Fong, Lon Wolf R. ; Qiao, Yawei ; Li, Xu ; Chen, Zhen ; Stephan, Clifford ; Deng, Weiye ; Ye, Rui ; Jiang, Wen ; Zhang, Shuxing ; Yu, Yonghao ; Hung, Mien-Chie ; Chen, Junjie ; Lin, Steven H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4363-14, Article 4363
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3D-QSAR, Docking, ADME/Tox studies on Flavone analogs reveal anticancer activity through Tankyrase inhibition
Author / Creator:Alam, Sarfaraz ; Khan, Feroz
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-04, Vol.9 (1), p.5414, Article 5414
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RK‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model
Author / Creator:Mizutani, Anna ; Yashiroda, Yoko ; Muramatsu, Yukiko ; Yoshida, Haruka ; Chikada, Tsubasa ; Tsumura, Takeshi ; Okue, Masayuki ; Shirai, Fumiyuki ; Fukami, Takehiro ; Yoshida, Minoru ; Seimiya, Hiroyuki
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-12, Vol.109 (12), p.4003-4014
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Inhibition of Tankyrases Induces Axin Stabilization and Blocks Wnt Signalling in Breast Cancer Cells
Author / Creator:Bao, Renyue ; Christova, Tania ; Song, Siyuan ; Angers, Stephane ; Yan, Xiaojun ; Attisano, Liliana
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e48670-e48670
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Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation
Author / Creator:Kim, Sukyeong ; Han, Sangbin ; Kim, Yeongjae ; Kim, Hyeon-Seop ; Gu, Young-Ran ; Kang, Donghyun ; Cho, Yongsik ; Kim, Hyeonkyeong ; Lee, Jeeyeon ; Seo, Yeyoung ; Chang, Moon Jong ; Chang, Chong Bum ; Kang, Seung-Baik ; Kim, Jin-Hong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-10, Vol.10 (1), p.4898-18, Article 4898
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Discovery of Novel Tankyrase Inhibitors through Molecular Docking-Based Virtual Screening and Molecular Dynamics Simulation Studies
Author / Creator:Berishvili, Vladimir P. ; Kuimov, Alexander N. ; Voronkov, Andrew E. ; Radchenko, Eugene V. ; Kumar, Pradeep ; Choonara, Yahya E. ; Pillay, Viness ; Kamal, Ahmed ; Palyulin, Vladimir A.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3171
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Tankyrase inhibition promotes endocrine commitment of hPSC-derived pancreatic progenitors
Author / Creator:Poon, Frankie ; Sambathkumar, Rangarajan ; Korytnikov, Roman ; Aghazadeh, Yasaman ; Oakie, Amanda ; Misra, Paraish S. ; Sarangi, Farida ; Nostro, M. Cristina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.8754-16, Article 8754
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XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway
Author / Creator:Tian, Xiao-Hong ; Hou, Wei-Jian ; Fang, Yan ; Fan, Jun ; Tong, Hao ; Bai, Shu-Ling ; Chen, Qu ; Xu, He ; Li, Yan
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2013-12, Vol.32 (1), p.100-100, Article 100
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The WNT/β-catenin signaling inhibitor XAV939 enhances the elimination of LNCaP and PC-3 prostate cancer cells by prostate cancer patient lymphocytes in vitro
Author / Creator:Stakheev, Dmitry ; Taborska, Pavla ; Strizova, Zuzana ; Podrazil, Michal ; Bartunkova, Jirina ; Smrz, Daniel
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-03, Vol.9 (1), p.4761-4761, Article 4761
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WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling
Author / Creator:James, Richard G. ; Davidson, Kathryn C. ; Bosch, Katherine A. ; Biechele, Travis L. ; Robin, Nicholas C. ; Taylor, Russell J. ; Major, Michael B. ; Camp, Nathan D. ; Fowler, Kerry ; Martins, Timothy J. ; Moon, Randall T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-12, Vol.7 (12), p.e50457-e50457
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Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway
Author / Creator:WU, XUEFANG ; LUO, FENG ; LI, JINBANG ; ZHONG, XUEYUN ; LIU, KUNPING
Publisher:Athens: D.A. Spandidos
Journal title:International journal of oncology, 2016-04, Vol.48 (4), p.1333-1340
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A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors
Author / Creator:Menon, Malini ; Elliott, Richard ; Bowers, Leandra ; Balan, Nicolae ; Rafiq, Rumana ; Costa-Cabral, Sara ; Munkonge, Felix ; Trinidade, Ines ; Porter, Roderick ; Campbell, Andrew D. ; Johnson, Emma R. ; Esdar, Christina ; Buchstaller, Hans-Peter ; Leuthner, Birgitta ; Rohdich, Felix ; Schneider, Richard ; Sansom, Owen ; Wienke, Dirk ; Ashworth, Alan ; Lord, Christopher J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-01, Vol.9 (1), p.201, Article 201
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Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling
Author / Creator:Distler, Alfiya ; Deloch, Lisa ; Huang, Jingang ; Dees, Clara ; Lin, Neng-Yu ; Palumbo-Zerr, Katrin ; Beyer, Christian ; Weidemann, Alexander ; Distler, Oliver ; Schett, Georg ; Distler, Jörg H W
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2013-09, Vol.72 (9), p.1575-1580
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Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening
Author / Creator:Li, Bo ; Liang, Jinxia ; Lu, Feng ; Zeng, Guandi ; Zhang, Jindao ; Ma, Yinxing ; Liu, Peng ; Wang, Qin ; Zhou, Qian ; Chen, Liang
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-04, Vol.25 (7), p.1680
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Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells
Author / Creator:Almasoud, Nuha ; Binhamdan, Sarah ; Younis, Ghaydaa ; Alaskar, Hanouf ; Alotaibi, Amal ; Manikandan, Muthurangan ; Alfayez, Musaad ; Kassem, Moustapha ; AlMuraikhi, Nihal
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.16746-16746, Article 16746
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Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
Author / Creator:Thorvaldsen, Tor Espen ; Pedersen, Nina Marie ; Wenzel, Eva Maria ; Stenmark, Harald
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-01, Vol.12 (1), p.e0170508-e0170508
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Showing 1 to 20 of 51 results

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Wnt/beta-catenin pathway: modulating anticancer immune response

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Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

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Tankyrase-targeted therapeutics: expanding opportunities in the PARP family

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Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling

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3D-QSAR, Docking, ADME/Tox studies on Flavone analogs reveal anticancer activity through Tankyrase inhibition

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RK‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model

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Inhibition of Tankyrases Induces Axin Stabilization and Blocks Wnt Signalling in Breast Cancer Cells

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Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation

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Discovery of Novel Tankyrase Inhibitors through Molecular Docking-Based Virtual Screening and Molecular Dynamics Simulation Studies

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Tankyrase inhibition promotes endocrine commitment of hPSC-derived pancreatic progenitors

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XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway

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The WNT/β-catenin signaling inhibitor XAV939 enhances the elimination of LNCaP and PC-3 prostate cancer cells by prostate cancer patient lymphocytes in vitro

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WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling

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Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway

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A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors

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Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling

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Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening

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Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells

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Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation

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