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ArticlesPeer ReviewedFull Text
Dynamic Metabolomics for Engineering Biology: Accelerating Learning Cycles for Bioproduction
Author / Creator:Vavricka, Christopher J ; Hasunuma, Tomohisa ; Kondo, Akihiko
Publisher:England: Elsevier Ltd
Journal title:Trends in biotechnology (Regular ed.), 2020-01, Vol.38 (1), p.68-82
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Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition
Author / Creator:Vavricka, Christopher J. ; Li, Qing ; Wu, Yan ; Qi, Jianxun ; Wang, Mingyang ; Liu, Yue ; Gao, Feng ; Liu, Jun ; Feng, Enguang ; He, Jianhua ; Wang, Jinfang ; Liu, Hong ; Jiang, Hualiang ; Gao, George F.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2011-10, Vol.7 (10), p.e1002249
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Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus
Author / Creator:Li, Qing ; Sun, Xiaoman ; Li, Zhixin ; Liu, Yue ; Vavricka, Christopher J. ; Qi, Jianxun ; Gao, George F.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.18897-18902
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3,4-Dihydroxyphenylacetaldehyde synthase evolved an ordered structure to deliver oxygen to pyridoxal 5’-phosphate for cuticle assembly in the mosquito Aedes aegypti
Author / Creator:Chen, Jing ; Vavricka, Christopher J. ; Wei, Shuangshuang ; Nakazawa, Yasumoto ; Matsumoto, Yuri ; Chen, Huaqing ; Tang, Yu ; Liang, Jing ; Chen, Jiukai ; Huang, Yaneng ; Noguchi, Keiichi ; Hasunuma, Tomohisa ; Guan, Huai ; Li, Jianyong ; Liao, Chenghong ; Han, Qian
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-05, Vol.16 (1), p.4486-13, Article 4486
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Enhancing carbohydrate repartitioning into lipid and carotenoid by disruption of microalgae starch debranching enzyme
Author / Creator:Kato, Yuichi ; Oyama, Tomoki ; Inokuma, Kentaro ; Vavricka, Christopher J. ; Matsuda, Mami ; Hidese, Ryota ; Satoh, Katsuya ; Oono, Yutaka ; Chang, Jo-Shu ; Hasunuma, Tomohisa ; Kondo, Akihiko
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-04, Vol.4 (1), p.450-11, Article 450
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Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Author / Creator:Wu, Yan ; Bi, Yuhai ; Vavricka, Christopher J ; Sun, Xiaoman ; Zhang, Yanfang ; Gao, Feng ; Zhao, Min ; Xiao, Haixia ; Qin, Chengfeng ; He, Jianhua ; Liu, Wenjun ; Yan, Jinghua ; Qi, Jianxun ; Gao, George F
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2013-12, Vol.23 (12), p.1347-1355
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ArticlesPeer ReviewedFull Text
Machine learning discovery of missing links that mediate alternative branches to plant alkaloids
Author / Creator:Vavricka, Christopher J. ; Takahashi, Shunsuke ; Watanabe, Naoki ; Takenaka, Musashi ; Matsuda, Mami ; Yoshida, Takanobu ; Suzuki, Ryo ; Kiyota, Hiromasa ; Li, Jianyong ; Minami, Hiromichi ; Ishii, Jun ; Tsuge, Kenji ; Araki, Michihiro ; Kondo, Akihiko ; Hasunuma, Tomohisa
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1405-1405, Article 1405
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Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids
Author / Creator:Vavricka, Christopher J. ; Yoshida, Takanobu ; Kuriya, Yuki ; Takahashi, Shunsuke ; Ogawa, Teppei ; Ono, Fumie ; Agari, Kazuko ; Kiyota, Hiromasa ; Li, Jianyong ; Ishii, Jun ; Tsuge, Kenji ; Minami, Hiromichi ; Araki, Michihiro ; Hasunuma, Tomohisa ; Kondo, Akihiko
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-05, Vol.10 (1), p.2015-2015, Article 2015
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Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis
Author / Creator:Takenaka, Musashi ; Kamasaka, Kouhei ; Daryong, Kim ; Tsuchikane, Keiko ; Miyazawa, Seiha ; Fujihana, Saeko ; Hori, Yoshimi ; Vavricka, Christopher J. ; Hosoyama, Akira ; Kawasaki, Hiroko ; Shirai, Tomokazu ; Araki, Michihiro ; Nakagawa, Akira ; Minami, Hiromichi ; Kondo, Akihiko ; Hasunuma, Tomohisa
Publisher:England: BioMed Central Ltd
Journal title:Microbial cell factories, 2024-06, Vol.23 (1), p.178-12, Article 178
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ArticlesPeer ReviewedFull Text
Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding
Author / Creator:Wu, Yan ; Qin, Guangrong ; Gao, Feng ; Liu, Yue ; Vavricka, Christopher J. ; Qi, Jianxun ; Jiang, Hualiang ; Yu, Kunqian ; Gao, George F.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2013-03, Vol.3 (1), p.1551-1551, Article 1551
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ArticlesPeer ReviewedFull Text
Proximity‐Unlocked Luminescence by Sequential Enzymatic Reactions from Antibody and Antibody/Aptamer (PULSERAA): A Platform for Detection and Visualization of Virus‐Containing Spots
Author / Creator:Miura, Daimei ; Hayashi, Wakana ; Hirano, Kensuke ; Sasaki, Ikkei ; Tsukakoshi, Kaori ; Kakizoe, Hidehumi ; Asai, Satomi ; Vavricka, Christopher J. ; Takemae, Hitoshi ; Mizutani, Tetsuya ; Tsugawa, Wakako ; Sode, Koji ; Ikebukuro, Kazunori ; Asano, Ryutaro
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2024-11, Vol.11 (43), p.e2403871-n/a
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ArticlesPeer ReviewedFull Text
Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality
Author / Creator:Vavricka, Christopher J. ; Muto, Chiaki ; Hasunuma, Tomohisa ; Kimura, Yoshinobu ; Araki, Michihiro ; Wu, Yan ; Gao, George F. ; Ohrui, Hiroshi ; Izumi, Minoru ; Kiyota, Hiromasa
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.8239-8, Article 8239
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ArticlesPeer ReviewedFull Text
Author Correction: Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids
Author / Creator:Vavricka, Christopher J. ; Yoshida, Takanobu ; Kuriya, Yuki ; Takahashi, Shunsuke ; Ogawa, Teppei ; Ono, Fumie ; Agari, Kazuko ; Kiyota, Hiromasa ; Li, Jianyong ; Ishii, Jun ; Tsuge, Kenji ; Minami, Hiromichi ; Araki, Michihiro ; Hasunuma, Tomohisa ; Kondo, Akihiko
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-05, Vol.10 (1), p.2336-2336, Article 2336
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ArticlesPeer ReviewedFull Text
Atypical group 1 neuraminidase pH1N1-N1 bound to a group 1 inhibitor
Author / Creator:Wu, Ying ; Vavricka, Christopher J. ; Wu, Yan ; Li, Qing ; Rudrawar, Santosh ; Thomson, Robin J. ; Itzstein, Mark von ; Gao, George F. ; Qi, Jianxun
Publisher:Beijing: Higher Education Press
Journal title:Protein & cell, 2015-10, Vol.6 (10), p.771-773
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ArticlesFull Text
Light/dark cycling causes delayed lipid accumulation and increased photoperiod-based biomass yield by altering metabolic flux in oleaginous Chlamydomonas sp
Author / Creator:Kato, Yuichi ; Fujihara, Yusuke ; Vavricka, Christopher J. ; Chang, Jo-Shu ; Hasunuma, Tomohisa ; Kondo, Akihiko
Publisher:England: BioMed Central Ltd
Journal title:Biotechnology for biofuels, 2019-02, Vol.12 (1), p.39-39, Article 39
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The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
Author / Creator:Li, Qing ; Qi, Jianxun ; Zhang, Wei ; Vavricka, Christopher J ; Shi, Yi ; Wei, Jinhua ; Feng, Enguang ; Shen, Jingshan ; Chen, Jilong ; Liu, Di ; He, Jianhua ; Yan, Jinghua ; Liu, Hong ; Jiang, Hualiang ; Teng, Maikun ; Li, Xuebing ; Gao, George F
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2010-10, Vol.17 (10), p.1266-1268
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ArticlesPeer ReviewedFull Text
Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Author / Creator:Vavricka, Christopher J. ; Liu, Yue ; Kiyota, Hiromasa ; Sriwilaijaroen, Nongluk ; Qi, Jianxun ; Tanaka, Kosuke ; Wu, Yan ; Li, Qing ; Li, Yan ; Yan, Jinghua ; Suzuki, Yasuo ; Gao, George F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013, Vol.4 (1), p.1491-1491, Article 1491
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Occurrence of complex type free N-glycans with a single GlcNAc residue at the reducing termini in the fresh-water plant, Egeria densa
Author / Creator:Maeda, Megumi ; Ebara, Natsuki ; Tani, Misato ; Vavricka, Christopher J. ; Kimura, Yoshinobu
Publisher:New York: Springer US
Journal title:Glycoconjugate journal, 2017-04, Vol.34 (2), p.229-240
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Purification and N-Glycosylation Analysis of Melanoma Antigen Dopachrome Tautomerase
Author / Creator:Vavricka, Christopher J. ; Ray, Keith W. ; Christensen, Bruce M. ; Li, Jianyong
Publisher:Boston: Springer US
Journal title:The Protein Journal, 2010-04, Vol.29 (3), p.204-212
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Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus
Author / Creator:Oladejo, Babayemi O ; Bi, Yuhai ; Vavricka, Christopher J ; Li, Chunrui ; Chai, Yan ; Xu, Kun ; Li, Liqiang ; Lu, Zhe ; Li, Jiandong ; Wong, Gary ; Mohan, Sankar ; Pinto, B Mario ; Jiang, Haihai ; Qi, Jianxun ; George Fu Gao ; Tien, Po ; Wu, Yan
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-07
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Dynamic Metabolomics for Engineering Biology: Accelerating Learning Cycles for Bioproduction

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Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition

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Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus

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3,4-Dihydroxyphenylacetaldehyde synthase evolved an ordered structure to deliver oxygen to pyridoxal 5’-phosphate for cuticle assembly in the mosquito Aedes aegypti

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Enhancing carbohydrate repartitioning into lipid and carotenoid by disruption of microalgae starch debranching enzyme

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Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses

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Machine learning discovery of missing links that mediate alternative branches to plant alkaloids

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Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids

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Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis

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Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

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Proximity‐Unlocked Luminescence by Sequential Enzymatic Reactions from Antibody and Antibody/Aptamer (PULSERAA): A Platform for Detection and Visualization of Virus‐Containing Spots

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Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality

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Author Correction: Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids

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Atypical group 1 neuraminidase pH1N1-N1 bound to a group 1 inhibitor

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Light/dark cycling causes delayed lipid accumulation and increased photoperiod-based biomass yield by altering metabolic flux in oleaginous Chlamydomonas sp

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The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site

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Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors

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Occurrence of complex type free N-glycans with a single GlcNAc residue at the reducing termini in the fresh-water plant, Egeria densa

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Purification and N-Glycosylation Analysis of Melanoma Antigen Dopachrome Tautomerase

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Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus

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