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ArticlesPeer ReviewedFull Text
Rolling back human pluripotent stem cells to an eight-cell embryo-like stage
Author / Creator:Mazid, Md. Abdul ; Ward, Carl ; Luo, Zhiwei ; Liu, Chuanyu ; Li, Yunpan ; Lai, Yiwei ; Wu, Liang ; Li, Jinxiu ; Jia, Wenqi ; Jiang, Yu ; Liu, Hao ; Fu, Lixin ; Yang, Yueli ; Ibañez, David P. ; Lai, Junjian ; Wei, Xiaoyu ; An, Juan ; Guo, Pengcheng ; Yuan, Yue ; Deng, Qiuting ; Wang, Yang ; Liu, Ying ; Gao, Fei ; Wang, Junwen ; Zaman, Shahriar ; Qin, Baoming ; Wu, Guangming ; Maxwell, Patrick H. ; Xu, Xun ; Liu, Longqi ; Li, Wenjuan ; Esteban, Miguel A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-05, Vol.605 (7909), p.315-324
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Maternal H3K27me3 controls DNA methylation-independent imprinting
Author / Creator:Inoue, Azusa ; Jiang, Lan ; Lu, Falong ; Suzuki, Tsukasa ; Zhang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-07, Vol.547 (7664), p.419-424
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Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Author / Creator:Flyamer, Ilya M. ; Gassler, Johanna ; Imakaev, Maxim ; Brandão, Hugo B. ; Ulianov, Sergey V. ; Abdennur, Nezar ; Razin, Sergey V. ; Mirny, Leonid A. ; Tachibana-Konwalski, Kikuë
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-04, Vol.544 (7648), p.110-114
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Inherent mosaicism and extensive mutation of human placentas
Author / Creator:Coorens, Tim H. H. ; Oliver, Thomas R. W. ; Sanghvi, Rashesh ; Sovio, Ulla ; Cook, Emma ; Vento-Tormo, Roser ; Haniffa, Muzlifah ; Young, Matthew D. ; Rahbari, Raheleh ; Sebire, Neil ; Campbell, Peter J. ; Charnock-Jones, D. Stephen ; Smith, Gordon C. S. ; Behjati, Sam
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-04, Vol.592 (7852), p.80-85
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Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
Author / Creator:Dahl, John Arne ; Jung, Inkyung ; Aanes, Håvard ; Greggains, Gareth D. ; Manaf, Adeel ; Lerdrup, Mads ; Li, Guoqiang ; Kuan, Samantha ; Li, Bin ; Lee, Ah Young ; Preissl, Sebastian ; Jermstad, Ingunn ; Haugen, Mads Haugland ; Suganthan, Rajikala ; Bjørås, Magnar ; Hansen, Klaus ; Dalen, Knut Tomas ; Fedorcsak, Peter ; Ren, Bing ; Klungland, Arne
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-09, Vol.537 (7621), p.548-552
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Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential
Author / Creator:Bolton, Helen ; Graham, Sarah J. L. ; Van der Aa, Niels ; Kumar, Parveen ; Theunis, Koen ; Fernandez Gallardo, Elia ; Voet, Thierry ; Zernicka-Goetz, Magdalena
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-03, Vol.7 (1), p.11165-12, Article 11165
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Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease
Author / Creator:Hyslop, Louise A. ; Blakeley, Paul ; Craven, Lyndsey ; Richardson, Jessica ; Fogarty, Norah M. E. ; Fragouli, Elpida ; Lamb, Mahdi ; Wamaitha, Sissy E. ; Prathalingam, Nilendran ; Zhang, Qi ; O’Keefe, Hannah ; Takeda, Yuko ; Arizzi, Lucia ; Alfarawati, Samer ; Tuppen, Helen A. ; Irving, Laura ; Kalleas, Dimitrios ; Choudhary, Meenakshi ; Wells, Dagan ; Murdoch, Alison P. ; Turnbull, Douglass M. ; Niakan, Kathy K. ; Herbert, Mary
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-06, Vol.534 (7607), p.383-386
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Minor zygotic gene activation is essential for mouse preimplantation development
Author / Creator:Abe, Ken-ichiro ; Funaya, Satoshi ; Tsukioka, Dai ; Kawamura, Machika ; Suzuki, Yutaka ; Suzuki, Masataka G. ; Schultz, Richard M. ; Aoki, Fugaku
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (29), p.E6780-E6788
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Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers
Author / Creator:Seisenberger, Stefanie ; Peat, Julian R. ; Hore, Timothy A. ; Santos, Fátima ; Dean, Wendy ; Reik, Wolf
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2013-01, Vol.368 (1609), p.20110330-20110330
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One-step generation of knockout pigs by zygote injection of CRISPR/Cas system
Author / Creator:Hai, Tang ; Teng, Fei ; Guo, Runfa ; Li, Wei ; Zhou, Qi
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2014-03, Vol.24 (3), p.372-375
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Fast and precise single-cell data analysis using a hierarchical autoencoder
Author / Creator:Tran, Duc ; Nguyen, Hung ; Tran, Bang ; La Vecchia, Carlo ; Luu, Hung N. ; Nguyen, Tin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1029-1029, Article 1029
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One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs
Author / Creator:Zuo, Erwei ; Cai, Yi-Jun ; Li, Kui ; Wei, Yu ; Wang, Bang-An ; Sun, Yidi ; Liu, Zhen ; Liu, Jiwei ; Hu, Xinde ; Wei, Wei ; Huo, Xiaona ; Shi, Linyu ; Tang, Cheng ; Liang, Dan ; Wang, Yan ; Nie, Yan-Hong ; Zhang, Chen-Chen ; Yao, Xuan ; Wang, Xing ; Zhou, Changyang ; Ying, Wenqin ; Wang, Qifang ; Chen, Ren-Chao ; Shen, Qi ; Xu, Guo-Liang ; Li, Jinsong ; Sun, Qiang ; Xiong, Zhi-Qi ; Yang, Hui
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2017-07, Vol.27 (7), p.933-945
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The landscape of RNA Pol II binding reveals a stepwise transition during ZGA
Author / Creator:Liu, Bofeng ; Xu, Qianhua ; Wang, Qiujun ; Feng, Su ; Lai, Fangnong ; Wang, Peizhe ; Zheng, Fangyuan ; Xiang, Yunlong ; Wu, Jingyi ; Nie, Junwei ; Qiu, Cui ; Xia, Weikun ; Li, Lijia ; Yu, Guang ; Lin, Zili ; Xu, Kai ; Xiong, Zhuqing ; Kong, Feng ; Liu, Ling ; Huang, Chunyi ; Yu, Yang ; Na, Jie ; Xie, Wei
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-11, Vol.587 (7832), p.139-144
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Genome–lamina interactions are established de novo in the early mouse embryo
Author / Creator:Borsos, Máté ; Perricone, Sara M. ; Schauer, Tamás ; Pontabry, Julien ; de Luca, Kim L. ; de Vries, Sandra S. ; Ruiz-Morales, Elias R. ; Torres-Padilla, Maria-Elena ; Kind, Jop
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-05, Vol.569 (7758), p.729-733
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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
Author / Creator:Gu, Tian-Peng ; Guo, Fan ; Yang, Hui ; Wu, Hai-Ping ; Xu, Gui-Fang ; Liu, Wei ; Xie, Zhi-Guo ; Shi, Linyu ; He, Xinyi ; Jin, Seung-gi ; Iqbal, Khursheed ; Shi, Yujiang Geno ; Deng, Zixin ; Szabó, Piroska E. ; Pfeifer, Gerd P. ; Li, Jinsong ; Xu, Guo-Liang
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-09, Vol.477 (7366), p.606-610
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Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
Author / Creator:Iqbal, Khursheed ; Jin, Seung-Gi ; Pfeifer, Gerd P ; Szabó, Piroska E
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (9), p.3642-3647
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Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos
Author / Creator:Chen, Zhiyuan ; Djekidel, Mohamed Nadhir ; Zhang, Yi
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-04, Vol.53 (4), p.551-563
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p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models
Author / Creator:Grow, Edward J. ; Weaver, Bradley D. ; Smith, Christina M. ; Guo, Jingtao ; Stein, Paula ; Shadle, Sean C. ; Hendrickson, Peter G. ; Johnson, Nicholas E. ; Butterfield, Russell J. ; Menafra, Roberta ; Kloet, Susan L. ; van der Maarel, Silvère M. ; Williams, Carmen J. ; Cairns, Bradley R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-08, Vol.53 (8), p.1207-1220
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KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Author / Creator:Sankar, Aditya ; Lerdrup, Mads ; Manaf, Adeel ; Johansen, Jens Vilstrup ; Gonzalez, Javier Martin ; Borup, Rehannah ; Blanshard, Robert ; Klungland, Arne ; Hansen, Klaus ; Andersen, Claus Yding ; Dahl, John Arne ; Helin, Kristian ; Hoffmann, Eva R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-04, Vol.22 (4), p.380-388
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A novel atypical sperm centriole is functional during human fertilization
Author / Creator:Fishman, Emily L. ; Jo, Kyoung ; Nguyen, Quynh P. H. ; Kong, Dong ; Royfman, Rachel ; Cekic, Anthony R. ; Khanal, Sushil ; Miller, Ann L. ; Simerly, Calvin ; Schatten, Gerald ; Loncarek, Jadranka ; Mennella, Vito ; Avidor-Reiss, Tomer
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-06, Vol.9 (1), p.2210-12, Article 2210
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Rolling back human pluripotent stem cells to an eight-cell embryo-like stage

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Maternal H3K27me3 controls DNA methylation-independent imprinting

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Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

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Inherent mosaicism and extensive mutation of human placentas

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Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

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Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential

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Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

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Minor zygotic gene activation is essential for mouse preimplantation development

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Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers

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One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

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Fast and precise single-cell data analysis using a hierarchical autoencoder

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One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

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The landscape of RNA Pol II binding reveals a stepwise transition during ZGA

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Genome–lamina interactions are established de novo in the early mouse embryo

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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

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Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

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Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos

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p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models

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KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

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A novel atypical sperm centriole is functional during human fertilization

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