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Select record 21
ArticlesPeer ReviewedFull Text
Analytical Solution to the Kinetics of Breakable Filament Assembly
Author / Creator:Knowles, Tuomas P.J ; Waudby, Christopher A ; Devlin, Glyn L ; Cohen, Samuel I.A ; Aguzzi, Adriano ; Vendruscolo, Michele ; Terentjev, Eugene M ; Welland, Mark E ; Dobson, Christopher M
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-12, Vol.326 (5959), p.1533-1537
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ArticlesPeer ReviewedFull Text
Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet
Author / Creator:Buchanan, Lauren E. ; Dunkelberger, Emily B. ; Tran, Huong Q. ; Cheng, Pin-Nan ; Chiu, Chi-Cheng ; Cao, Ping ; Raleigh, Daniel P. ; de Pablo, Juan J. ; Nowick, James S. ; Zanni, Martin T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19285-19290
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Select record 23
ArticlesPeer ReviewedFull Text
Crucial role of nonspecific interactions in amyloid nucleation
Author / Creator:Šarić, Anđela ; Chebaro, Yassmine C. ; Knowles, Tuomas P. J. ; Frenkel, Daan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.17869-17874
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Atomic View of a Toxic Amyloid Small Oligomer
Author / Creator:Laganowsky, Arthur ; Liu, Cong ; Sawaya, Michael R. ; Whitelegge, Julian P. ; Park, Jiyong ; Zhao, Minglei ; Pensalfini, Anna ; Soriaga, Angela B. ; Landau, Meytal ; Teng, Poh K. ; Cascio, Duilio ; Glabe, Charles ; Eisenberg, David
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6073), p.1228-1231
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Identifying the amylome, proteins capable of forming amyloid-like fibrils
Author / Creator:Goldschmidt, Lukasz ; Teng, Poh K ; Riek, Roland ; Eisenberg, David
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3487-3492
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Select record 26
ArticlesPeer ReviewedFull Text
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice
Author / Creator:Stöhr, Jan ; Condello, Carlo ; Watts, Joel C. ; Bloch, Lillian ; Oehler, Abby ; Nick, Mimi ; DeArmond, Stephen J. ; Giles, Kurt ; DeGrado, William F. ; Prusiner, Stanley B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10329-10334
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Select record 27
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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity
Author / Creator:Friedrich, Ralf P ; Tepper, Katharina ; Rönicke, Raik ; Soom, Malle ; Westermann, Martin ; Reymann, Klaus ; Kaether, Christoph ; Fändrich, Marcus
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (5), p.1942-1947
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Structure-neurotoxicity relationships of amyloid β-protein oligomers
Author / Creator:Ono, Kenjiro ; Condron, Margaret M ; Teplow, David B
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (35), p.14745-14750
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Select record 29
ArticlesPeer ReviewedFull Text
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
Author / Creator:Bieschke, Jan ; Russ, Jenny ; Friedrich, Ralf P ; Ehrnhoefer, Dagmar E ; Wobst, Heike ; Neugebauer, Katja ; Wanker, Erich E
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (17), p.7710-7715
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Select record 30
ArticlesPeer ReviewedFull Text
Toxic fibrillar oligomers of amyloid-β have cross-β structure
Author / Creator:Stroud, James C ; Liu, Cong ; Teng, Poh K ; Eisenberg, David
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (20), p.7717-7722
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Select record 31
ArticlesPeer ReviewedFull Text
Monomer adds to preformed structured oligomers of Aβ-peptides by a two-stage dock-lock mechanism
Author / Creator:Nguyen, Phuong H ; Li, Mai Suan ; Stock, Gerhard ; Straub, John E ; Thirumalai, D
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (1), p.111-116
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Select record 32
ArticlesPeer ReviewedFull Text
Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation
Author / Creator:Crick, Scott L. ; Ruff, Kiersten M. ; Garai, Kanchan ; Frieden, Carl ; Pappu, Rohit V.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (50), p.20075-20080
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Select record 33
ArticlesPeer ReviewedFull Text
Structure of an Intermediate State in Protein Folding and Aggregation
Author / Creator:Neudecker, Philipp ; Robustelli, Paul ; Cavalli, Andrea ; Walsh, Patrick ; Lundström, Patrik ; Zarrine-Afsar, Arash ; Sharpe, Simon ; Vendruscolo, Michele ; Kay, Lewis E.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6079), p.362-366
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Select record 34
ArticlesPeer ReviewedFull Text
Molecular basis for amyloid-β polymorphism
Author / Creator:Colletier, Jacques-Philippe ; Laganowsky, Arthur ; Landau, Meytal ; Zhao, Minglei ; Soriaga, Angela B ; Goldschmidt, Lukasz ; Flot, David ; Cascio, Duilio ; Sawaya, Michael R ; Eisenberg, David
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.16938-16943
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Select record 35
ArticlesPeer ReviewedFull Text
Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
Author / Creator:Luk, Kelvin C ; Song, Cheng ; O'Brien, Patrick ; Stieber, Anna ; Branch, Jonathan R ; Brunden, Kurt R ; Trojanowski, John Q ; Lee, Virginia M.-Y
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.20051-20056
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Select record 36
ArticlesPeer ReviewedFull Text
Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions
Author / Creator:Stöhr, Jan ; Watts, Joel C ; Mensinger, Zachary L ; Oehler, Abby ; Grillo, Sunny K ; DeArmond, Stephen J ; Prusiner, Stanley B ; Giles, Kurt
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.11025-11030
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Select record 37
ArticlesPeer ReviewedFull Text
Comparison of Alzheimer Aβ(1-40) and Aβ(1-42) amyloid fibrils reveals similar protofilament structures
Author / Creator:Schmidt, Matthias ; Sachse, Carsten ; Richter, Walter ; Xu, Chen ; Fändrich, Marcus ; Grigorieff, Nikolaus
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.19813-19818
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Select record 38
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Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils
Author / Creator:Qiang, Wei ; Yau, Wai-Ming ; Luo, Yongquan ; Mattson, Mark P ; Tycko, Robert
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4443-4448
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Select record 39
ArticlesPeer ReviewedFull Text
Amyloid Fibrils of the HET-s(218-289) Prion Form a β Solenoid with a Triangular Hydrophobic Core
Author / Creator:Wasmer, Christian ; Lange, Adam ; Van Melckebeke, Hélène ; Siemer, Ansgar B ; Riek, Roland ; Meier, Beat H
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5869), p.1523-1526
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Select record 40
ArticlesPeer ReviewedFull Text
Mapping amorphous calcium phosphate transformation into crystalline mineral from the cell to the bone in zebrafish fin rays
Author / Creator:Mahamid, Julia ; Aichmayer, Barbara ; Shimoni, Eyal ; Ziblat, Roy ; Li, Chenghao ; Siegel, Stefan ; Paris, Oskar ; Fratzl, Peter ; Weiner, Steve ; Addadi, Lia
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (14), p.6316-6321
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Analytical Solution to the Kinetics of Breakable Filament Assembly

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Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet

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Crucial role of nonspecific interactions in amyloid nucleation

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Atomic View of a Toxic Amyloid Small Oligomer

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Identifying the amylome, proteins capable of forming amyloid-like fibrils

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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity

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Structure-neurotoxicity relationships of amyloid β-protein oligomers

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EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

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Toxic fibrillar oligomers of amyloid-β have cross-β structure

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Monomer adds to preformed structured oligomers of Aβ-peptides by a two-stage dock-lock mechanism

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Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation

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Structure of an Intermediate State in Protein Folding and Aggregation

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Molecular basis for amyloid-β polymorphism

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Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

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Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

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Comparison of Alzheimer Aβ(1-40) and Aβ(1-42) amyloid fibrils reveals similar protofilament structures

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Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils

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Amyloid Fibrils of the HET-s(218-289) Prion Form a β Solenoid with a Triangular Hydrophobic Core

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Mapping amorphous calcium phosphate transformation into crystalline mineral from the cell to the bone in zebrafish fin rays

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