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123 results for Apoptosis+Regulatory+Proteins+-+deficiency

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ArticlesPeer ReviewedFull Text
NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells
Author / Creator:Eisenbarth, Stephanie C. ; Williams, Adam ; Colegio, Oscar R. ; Meng, Hailong ; Strowig, Till ; Rongvaux, Anthony ; Henao-Mejia, Jorge ; Thaiss, Christoph A. ; Joly, Sophie ; Gonzalez, David G. ; Xu, Lan ; Zenewicz, Lauren A. ; Haberman, Ann M. ; Elinav, Eran ; Kleinstein, Steven H. ; Sutterwala, Fayyaz S. ; Flavell, Richard A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-04, Vol.484 (7395), p.510-513
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Puma is required for p53-induced depletion of adult stem cells
Author / Creator:Liu, Dongping ; Ou, Linda ; Clemenson, Gregory D. ; Chao, Connie ; Lutske, Marshall Eli ; Zambetti, Gerard P. ; Gage, Fred H. ; Xu, Yang
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2010-10, Vol.12 (10), p.993-998
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Serine/Threonine Kinase 17A Is a Novel Candidate for Therapeutic Targeting in Glioblastoma
Author / Creator:Mao, Pingping ; Hever-Jardine, Mary P. ; Rahme, Gilbert J. ; Yang, Eric ; Tam, Janice ; Kodali, Anita ; Biswal, Bijesh ; Fadul, Camilo E. ; Gaur, Arti ; Israel, Mark A. ; Spinella, Michael J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-11, Vol.8 (11), p.e81803
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Author / Creator:He, Wan-ting ; Wan, Haoqiang ; Hu, Lichen ; Chen, Pengda ; Wang, Xin ; Huang, Zhe ; Yang, Zhang-Hua ; Zhong, Chuan-Qi ; Han, Jiahuai
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2015-12, Vol.25 (12), p.1285-1298
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Author / Creator:Shi, Jianjin ; Zhao, Yue ; Wang, Kun ; Shi, Xuyan ; Wang, Yue ; Huang, Huanwei ; Zhuang, Yinghua ; Cai, Tao ; Wang, Fengchao ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-10, Vol.526 (7575), p.660-665
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Author / Creator:Kayagaki, Nobuhiko ; Stowe, Irma B. ; Lee, Bettina L. ; O’Rourke, Karen ; Anderson, Keith ; Warming, Søren ; Cuellar, Trinna ; Haley, Benjamin ; Roose-Girma, Merone ; Phung, Qui T. ; Liu, Peter S. ; Lill, Jennie R. ; Li, Hong ; Wu, Jiansheng ; Kummerfeld, Sarah ; Zhang, Juan ; Lee, Wyne P. ; Snipas, Scott J. ; Salvesen, Guy S. ; Morris, Lucy X. ; Fitzgerald, Linda ; Zhang, Yafei ; Bertram, Edward M. ; Goodnow, Christopher C. ; Dixit, Vishva M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-10, Vol.526 (7575), p.666-671
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NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Author / Creator:He, Yuan ; Zeng, Melody Y. ; Yang, Dahai ; Motro, Benny ; Núñez, Gabriel
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7590), p.354-357
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Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction
Author / Creator:Lam, Hilaire C. ; Cloonan, Suzanne M. ; Bhashyam, Abhiram R. ; Haspel, Jeffery A. ; Singh, Anju ; Sathirapongsasuti, J. Fah ; Cervo, Morgan ; Yao, Hongwei ; Chung, Anna L. ; Mizumura, Kenji ; An, Chang Hyeok ; Shan, Bin ; Franks, Jonathan M. ; Haley, Kathleen J. ; Owen, Caroline A. ; Tesfaigzi, Yohannes ; Washko, George R. ; Quackenbush, John ; Silverman, Edwin K. ; Rahman, Irfan ; Kim, Hong Pyo ; Mahmood, Ashfaq ; Biswal, Shyam S. ; Ryter, Stefan W. ; Choi, Augustine M.K.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-12, Vol.123 (12), p.5212-5230
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ArticlesPeer ReviewedFull Text
NAIP–NLRC4-deficient mice are susceptible to shigellosis
Author / Creator:Mitchell, Patrick S ; Roncaioli, Justin L ; Turcotte, Elizabeth A ; Goers, Lisa ; Chavez, Roberto A ; Lee, Angus Y ; Lesser, Cammie F ; Rauch, Isabella ; Vance, Russell E
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-10, Vol.9
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The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases
Author / Creator:Li, Mei
Publisher:New York: Springer US
Journal title:Apoptosis (London), 2021-06, Vol.26 (5-6), p.235-247
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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
Author / Creator:von Moltke, Jakob ; Trinidad, Norver J. ; Moayeri, Mahtab ; Kintzer, Alexander F. ; Wang, Samantha B. ; van Rooijen, Nico ; Brown, Charles R. ; Krantz, Bryan A. ; Leppla, Stephen H. ; Gronert, Karsten ; Vance, Russell E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-10, Vol.490 (7418), p.107-111
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ArticlesPeer ReviewedFull Text
Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation
Author / Creator:Lopez-Ramirez, Miguel Alejandro ; Lai, Catherine Chinhchu ; Soliman, Shady Ibrahim ; Hale, Preston ; Pham, Angela ; Estrada, Esau J. ; McCurdy, Sara ; Girard, Romuald ; Verma, Riya ; Moore, Thomas ; Lightle, Rhonda ; Hobson, Nicholas ; Shenkar, Robert ; Poulsen, Orit ; Haddad, Gabriel G. ; Daneman, Richard ; Gongol, Brendan ; Sun, Hao ; Lagarrigue, Frederic ; Awad, Issam A. ; Ginsberg, Mark H.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-07, Vol.131 (13)
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The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity
Author / Creator:Wali, J A ; Rondas, D ; McKenzie, M D ; Zhao, Y ; Elkerbout, L ; Fynch, S ; Gurzov, E N ; Akira, S ; Mathieu, C ; Kay, T W H ; Overbergh, L ; Strasser, A ; Thomas, H E
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2014-03, Vol.5 (3), p.e1124-e1124
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Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility
Author / Creator:Nguyen, Quynh-Nhu ; Zerafa, Nadeen ; Liew, Seng H. ; Morgan, F. Hamish ; Strasser, Andreas ; Scott, Clare L. ; Findlay, Jock K. ; Hickey, Martha ; Hutt, Karla J.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-05, Vol.9 (6), p.618-12, Article 618
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BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program
Author / Creator:Ren, Decheng ; Tu, Ho-Chou ; Kim, Hyungjin ; Wang, Gary X ; Bean, Gregory R ; Takeuchi, Osamu ; Jeffers, John R ; Zambetti, Gerard P ; Hsieh, James J.-D ; Cheng, Emily H.-Y
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6009), p.1390-1393
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Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model
Author / Creator:Zhou, Huanjiao Jenny ; Qin, Lingfeng ; Jiang, Quan ; Murray, Katie N. ; Zhang, Haifeng ; Li, Busu ; Lin, Qun ; Graham, Morven ; Liu, Xinran ; Grutzendler, Jaime ; Min, Wang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.504-504, Article 504
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Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor
Author / Creator:Gawriluk, Thomas R. ; Ko, CheMyong ; Hong, Xiaoman ; Christenson, Lane K. ; Rucker, Edmund B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (40), p.E4194-E4203
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Novel Murine Models of Cerebral Cavernous Malformations
Author / Creator:Detter, Matthew R. ; Shenkar, Robert ; Benavides, Christian R. ; Neilson, Catherine A. ; Moore, Thomas ; Lightle, Rhonda ; Hobson, Nicholas ; Shen, Le ; Cao, Ying ; Girard, Romuald ; Zhang, Dongdong ; Griffin, Erin ; Gallione, Carol J. ; Awad, Issam A. ; Marchuk, Douglas A.
Publisher:Dordrecht: Springer Netherlands
Journal title:Angiogenesis (London), 2020-11, Vol.23 (4), p.651-666
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Insulin receptor substrate signaling suppresses neonatal autophagy in the heart
Author / Creator:Riehle, Christian ; Wende, Adam R. ; Sena, Sandra ; Pires, Karla Maria ; Pereira, Renata Oliveira ; Zhu, Yi ; Bugger, Heiko ; Frank, Deborah ; Bevins, Jack ; Chen, Dong ; Perry, Cynthia N. ; Dong, Xiaocheng C. ; Valdez, Steven ; Rech, Monika ; Sheng, Xiaoming ; Weimer, Bart C. ; Gottlieb, Roberta A. ; White, Morris F. ; Abel, E. Dale
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-12, Vol.123 (12), p.5319-5333
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ArticlesPeer ReviewedFull Text
Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy
Author / Creator:Grabinger, T ; Luks, L ; Kostadinova, F ; Zimberlin, C ; Medema, J P ; Leist, M ; Brunner, T
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2014-05, Vol.5 (5), p.e1228-e1228
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Showing 1 to 20 of 123 results

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NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells

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Puma is required for p53-induced depletion of adult stem cells

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Serine/Threonine Kinase 17A Is a Novel Candidate for Therapeutic Targeting in Glioblastoma

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

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NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

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Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction

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NAIP–NLRC4-deficient mice are susceptible to shigellosis

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The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases

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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

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Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation

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The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

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Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility

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BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

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Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model

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Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor

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Novel Murine Models of Cerebral Cavernous Malformations

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Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

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Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy

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