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ArticlesPeer ReviewedFull Text
Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS
Author / Creator:Huang, William Y. C. ; Yan, Qingrong ; Lin, Wan-Chen ; Chung, Jean K. ; Hansen, Scott D. ; Christensen, Sune M. ; Tu, Hsiung-Lin ; Kuriyan, John ; Groves, Jay T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8218-8223
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ArticlesPeer ReviewedFull Text
Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction
Author / Creator:Hansen, Scott D. ; Huang, William Y. C. ; Lee, Young Kwang ; Bieling, Peter ; Christensen, Sune M. ; Groves, Jay T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (30), p.15013-15022
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ArticlesPeer ReviewedFull Text
H-Ras forms dimers on membrane surfaces via a protein—protein interface
Author / Creator:Lin, Wan-Chen ; Iversen, Lars ; Tu, Hsiung-Lin ; Rhodes, Christopher ; Christensen, Sune M. ; Iwig, Jeffrey S. ; Hansen, Scott D. ; Huang, William Y. C. ; Groves, Jay T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.2996-3001
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ArticlesPeer ReviewedFull Text
Direct observation of proton pumping by a eukaryotic P-type ATPase
Author / Creator:Veshaguri, Salome ; Christensen, Sune M. ; Kemmer, Gerdi C. ; Ghale, Garima ; Møller, Mads P. ; Lohr, Christina ; Christensen, Andreas L. ; Justesen, Bo H. ; Jørgensen, Ida L. ; Schiller, Jürgen ; Hatzakis, Nikos S. ; Grabe, Michael ; Pomorski, Thomas Günther ; Stamou, Dimitrios
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-03, Vol.351 (6280), p.1469-1473
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ArticlesPeer ReviewedFull Text
Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
Author / Creator:Inversen, Lars ; Tu, Hsiung-Lin ; Lin, Wan-Chen ; Christensen, Sune M. ; Abel, Steven M. ; Iwig, Jeff ; Wu, Hung-Jen ; Gureasko, Jodi ; Rhodes, Christopher ; Petit, Rebecca S. ; Hansen, Scott D. ; Thill, Peter ; Yu, Cheng-Han ; Stamou, Dimitrios ; Chakraborty, Arup K. ; Kuriyan, John ; Groves, Jay T.
Publisher:Washington: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-07, Vol.345 (6192), p.50-54
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ArticlesPeer ReviewedFull Text
Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes
Author / Creator:Mathiasen, Signe ; Christensen, Sune M ; Fung, Juan José ; Rasmussen, Søren G F ; Fay, Jonathan F ; Jorgensen, Sune K ; Veshaguri, Salome ; Farrens, David L ; Kiskowski, Maria ; Kobilka, Brian ; Stamou, Dimitrios
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2014-09, Vol.11 (9), p.931-934
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ArticlesPeer ReviewedFull Text
A Fluorescence-Based Technique to Construct Size Distributions from Single-Object Measurements: Application to the Extrusion of Lipid Vesicles
Author / Creator:Kunding, Andreas H. ; Mortensen, Michael W. ; Christensen, Sune M. ; Stamou, Dimitrios
Publisher:United States: Elsevier Inc
Journal title:Biophysical journal, 2008-08, Vol.95 (3), p.1176-1188
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ArticlesPeer ReviewedFull Text
Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity
Author / Creator:Stratton, Margaret ; Lee, Il-Hyung ; Bhattacharyya, Moitrayee ; Christensen, Sune M ; Chao, Luke H ; Schulman, Howard ; Groves, Jay T ; Kuriyan, John
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-01, Vol.3, p.e01610-e01610
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ArticlesPeer ReviewedFull Text
Single-Particle Tracking of Thermomyces lanuginosus Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion
Author / Creator:Iversen, Josephine F ; Bohr, Søren S-R ; Pinholt, Henrik D ; Moses, Matias E ; Iversen, Lars ; Christensen, Sune M ; Hatzakis, Nikos S ; Zhang, Min
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-03, Vol.13 (4), p.631
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ArticlesPeer ReviewedFull Text
Sensing-applications of surface-based single vesicle arrays
Author / Creator:Christensen, Sune M ; Stamou, Dimitrios G
Publisher:Switzerland: MDPI AG
Journal title:Sensors (Basel, Switzerland), 2010-12, Vol.10 (12), p.11352-11368
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ArticlesPeer ReviewedFull Text
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
Author / Creator:Laursen, Tomas ; Lam, Hiu Yue Monatrice ; Sørensen, Kasper Kildegaard ; Tian, Pengfei ; Hansen, Cecilie Cetti ; Groves, Jay T. ; Jensen, Knud Jørgen ; Christensen, Sune M.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-09, Vol.4 (1), p.1057-1057, Article 1057
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ArticlesPeer ReviewedFull Text
Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition
Author / Creator:Bohr, Søren S.-R. ; Lund, Philip M. ; Kallenbach, Amalie S. ; Pinholt, Henrik ; Thomsen, Johannes ; Iversen, Lars ; Svendsen, Allan ; Christensen, Sune M. ; Hatzakis, Nikos S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-11, Vol.9 (1), p.16169-11, Article 16169
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ArticlesPeer ReviewedFull Text
One-way membrane trafficking of SOS in receptor-triggered Ras activation
Author / Creator:Christensen, Sune M ; Tu, Hsiung-Lin ; Jun, Jesse E ; Alvarez, Steven ; Triplet, Meredith G ; Iwig, Jeffrey S ; Yadav, Kamlesh K ; Bar-Sagi, Dafna ; Roose, Jeroen P ; Groves, Jay T
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2016-09, Vol.23 (9), p.838-846
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ArticlesPeer ReviewedFull Text
Mixing subattolitre volumes in a quantitative and highly parallel manner with soft matter nanofluidics
Author / Creator:Christensen, Sune M. ; Bolinger, Pierre-Yves ; Hatzakis, Nikos S. ; Mortensen, Michael W. ; Stamou, Dimitrios
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2012-01, Vol.7 (1), p.51-55
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ArticlesPeer ReviewedFull Text
Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity
Author / Creator:Stratton, Margaret ; Lee, Il-Hyung ; Bhattacharyya, Moitrayee ; Christensen, Sune M ; Chao, Luke H ; Schulman, Howard ; Groves, Jay T ; Kuriyan, John
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-02, Vol.3, p.e02490-e02490
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ArticlesPeer ReviewedFull Text
Single-Particle Tracking of IThermomyces lanuginosus/I Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion
Author / Creator:Iversen, Josephine F ; Bohr, Søren S.-R ; Pinholt, Henrik D ; Moses, Matias E ; Iversen, Lars ; Christensen, Sune M ; Hatzakis, Nikos S ; Zhang, Min
Publisher:MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-03, Vol.13 (4)
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ArticlesPeer ReviewedFull Text
Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics
Author / Creator:Iversen, Lars ; Tu, Hsiung-Lin ; Lin, Wan-Chen ; Christensen, Sune M ; Abel, Steven M ; Iwig, Jeff ; Wu, Hung-Jen ; Gureasko, Jodi ; Rhodes, Christopher ; Petit, Rebecca S ; Hansen, Scott D ; Thill, Peter ; Yu, Cheng-Han ; Stamou, Dimitrios ; Chakraborty, Arup K ; Kuriyan, John ; Groves, Jay T
Publisher:United States
Journal title:Science (American Association for the Advancement of Science), 2014-07, Vol.345 (6192), p.50-54
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ArticlesFull Text
Direct observation of assembly and function of trigger responsive lipase biohybrids
Author / Creator:Voutyritsa, Errika ; Soerensen, Emily W ; Oikonomou, Athanasios ; Lazou, Thomai ; Bushi, Jonida ; Christensen, Sune M ; Velonia, Kelly ; Hatzakis, Nikos S
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2024-12
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ReportsFull Text
Single-Particle Tracking of IThermomyces lanuginosus/I Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion
Author / Creator:Iversen, Josephine F ; Bohr, Søren S.-R ; Pinholt, Henrik D ; Moses, Matias E ; Iversen, Lars ; Christensen, Sune M ; Hatzakis, Nikos S ; Zhang, Min
Publisher:MDPI AG
Journal title:Biomolecules, 2023, Vol.13 (4)
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ReportsFull Text
One-way membrane trafficking of SOS in receptor-triggered Ras activation
Author / Creator:Christensen, Sune M ; Tu, Hsiung-Lin ; Jun, Jesse E ; Alvarez, Steven ; Triplet, Meredith G ; Iwig, Jeffrey S ; Yadav, Kamlesh K ; Bar-Sagi, Dafna ; Roose, Jeroen P ; Groves, Jay T
Publisher:Nature Publishing Group
Journal title:Nature Structural and Molecular Biology, 2016, Vol.23 (9), p.838
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Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS

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Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

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H-Ras forms dimers on membrane surfaces via a protein—protein interface

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Direct observation of proton pumping by a eukaryotic P-type ATPase

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Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics

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Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

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A Fluorescence-Based Technique to Construct Size Distributions from Single-Object Measurements: Application to the Extrusion of Lipid Vesicles

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Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity

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Single-Particle Tracking of Thermomyces lanuginosus Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion

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Sensing-applications of surface-based single vesicle arrays

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Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

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Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition

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One-way membrane trafficking of SOS in receptor-triggered Ras activation

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Mixing subattolitre volumes in a quantitative and highly parallel manner with soft matter nanofluidics

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Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity

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Single-Particle Tracking of IThermomyces lanuginosus/I Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion

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Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics

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Direct observation of assembly and function of trigger responsive lipase biohybrids

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Single-Particle Tracking of IThermomyces lanuginosus/I Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion

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One-way membrane trafficking of SOS in receptor-triggered Ras activation

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