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ArticlesPeer ReviewedFull Text
Fibroblast Growth Factor 21—Metabolic Role in Mice and Men
Author / Creator:Staiger, Harald ; Keuper, Michaela ; Berti, Lucia ; Hrabě de Angelis, Martin ; Häring, Hans-Ulrich
Publisher:Washington, DC: Endocrine Society
Journal title:Endocrine reviews, 2017-10, Vol.38 (5), p.468-488
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Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice
Author / Creator:Keipert, Susanne ; Lutter, Dominik ; Schroeder, Bjoern O. ; Brandt, Daniel ; Ståhlman, Marcus ; Schwarzmayr, Thomas ; Graf, Elisabeth ; Fuchs, Helmut ; de Angelis, Martin Hrabe ; Tschöp, Matthias H. ; Rozman, Jan ; Jastroch, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.624-12, Article 624
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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo
Author / Creator:Hönes, G. Sebastian ; Rakov, Helena ; Logan, John ; Liao, Xiao-Hui ; Werbenko, Eugenie ; Pollard, Andrea S. ; Præstholm, Stine M. ; Siersbæk, Majken S. ; Rijntjes, Eddy ; Gassen, Janina ; Latteyer, Sören ; Engels, Kathrin ; Strucksberg, Karl-Heinz ; Kleinbongard, Petra ; Zwanziger, Denise ; Rozman, Jan ; Gailus-Durner, Valerie ; Fuchs, Helmut ; de Angelis, Martin Hrabe ; Klein-Hitpass, Ludger ; Köhrle, Josef ; Armstrong, David L. ; Grøntved, Lars ; Bassett, J. H. Duncan ; Williams, Graham R. ; Refetoff, Samuel ; Führer, Dagmar ; Moeller, Lars C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (52), p.E11323-E11332
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Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes
Author / Creator:Vegiopoulos, Alexandros ; Müller-Decker, Karin ; Strzoda, Daniela ; Schmitt, Iris ; Chichelnitskiy, Evgeny ; Ostertag, Anke ; Diaz, Mauricio Berriel ; Rozman, Jan ; Hrabe de Angelis, Martin ; Nüsing, Rolf M ; Meyer, Carola W ; Wahli, Walter ; Klingenspor, Martin ; Herzig, Stephan
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-05, Vol.328 (5982), p.1158-1161
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Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach
Author / Creator:Scavizzi, Ferdinando ; Ryder, Edward ; Newman, Stuart ; Raspa, Marcello ; Gleeson, Diane ; Wardle-Jones, Hannah ; Montoliu, Lluis ; Fernandez, Almudena ; Dessain, Marie-Laure ; Larrigaldie, Vanessa ; Khorshidi, Zuzana ; Vuolteenaho, Reetta ; Soininen, Raija ; André, Philippe ; Jacquot, Sylvie ; Hong, Yi ; de Angelis, Martin Hrabe ; Ramirez-Solis, Ramiro ; Doe, Brendan
Publisher:Cham: Springer International Publishing
Journal title:Transgenic research, 2015-10, Vol.24 (5), p.921-927
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Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification
Author / Creator:Santos, Maria C. Ferreira dos ; Anderson, Cole P. ; Neschen, Susanne ; Zumbrennen-Bullough, Kimberly B. ; Romney, Steven J. ; Kahle-Stephan, Melanie ; Rathkolb, Birgit ; Gailus-Durner, Valerie ; Fuchs, Helmut ; Wolf, Eckhard ; Rozman, Jan ; de Angelis, Martin Hrabe ; Cai, Weiling Maggie ; Rajan, Malini ; Hu, Jennifer ; Dedon, Peter C. ; Leibold, Elizabeth A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.296-296, Article 296
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Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
Author / Creator:Keller, Johannes ; Catala-Lehnen, Philip ; Huebner, Antje K. ; Jeschke, Anke ; Heckt, Timo ; Lueth, Anja ; Krause, Matthias ; Koehne, Till ; Albers, Joachim ; Schulze, Jochen ; Schilling, Sarah ; Haberland, Michael ; Denninger, Hannah ; Neven, Mona ; Hermans-Borgmeyer, Irm ; Streichert, Thomas ; Breer, Stefan ; Barvencik, Florian ; Levkau, Bodo ; Rathkolb, Birgit ; Wolf, Eckhard ; Calzada-Wack, Julia ; Neff, Frauke ; Gailus-Durner, Valerie ; Fuchs, Helmut ; de Angelis, Martin Hrab[ebreve] ; Klutmann, Susanne ; Tsourdi, Elena ; Hofbauer, Lorenz C. ; Kleuser, Burkhard ; Chun, Jerold ; Schinke, Thorsten ; Amling, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-10, Vol.5 (1), p.5215-5215, Article 5215
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ArticlesPeer ReviewedFull Text
Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ
Author / Creator:Hönes, Georg Sebastian ; Geist, Daniela ; Wenzek, Christina ; Pfluger, Paul Thomas ; Müller, Timo Dirk ; Aguilar-Pimentel, Juan Antonio ; Amarie, Oana Veronica ; Becker, Lore ; Dragano, Natalia ; Garrett, Lillian ; Hölter, Sabine Maria ; Rathkolb, Birgit ; Rozman, Jan ; Spielmann, Nadine ; Treise, Irina ; Wolf, Eckhard ; Wurst, Wolfgang ; Fuchs, Helmut ; Gailus-Durner, Valerie ; Hrabe de Angelis, Martin ; Führer, Dagmar ; Moeller, Lars Christian
Publisher:US: Oxford University Press
Journal title:Endocrinology (Philadelphia), 2024-07, Vol.165 (8)
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TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity
Author / Creator:Tollot-Wegner, Marie ; Jessen, Marco ; Kim, KyungMok ; Sanz-Moreno, Adrián ; Spielmann, Nadine ; Gailus-Durner, Valerie ; Fuchs, Helmut ; Hrabe de Angelis, Martin ; von Eyss, Björn
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2024-05, Vol.26 (1), p.74-74, Article 74
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ArticlesPeer ReviewedFull Text
Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes
Author / Creator:Wagner, Robert ; Heni, Martin ; Tabák, Adam G. ; Machann, Jürgen ; Schick, Fritz ; Randrianarisoa, Elko ; Hrabě de Angelis, Martin ; Birkenfeld, Andreas L. ; Stefan, Norbert ; Peter, Andreas ; Häring, Hans-Ulrich ; Fritsche, Andreas
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-01, Vol.27 (1), p.49-57
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Single-cell, whole-embryo phenotyping of mammalian developmental disorders
Author / Creator:Huang, Xingfan ; Henck, Jana ; Qiu, Chengxiang ; Sreenivasan, Varun K. A. ; Balachandran, Saranya ; Amarie, Oana V. ; Hrabě de Angelis, Martin ; Behncke, Rose Yinghan ; Chan, Wing-Lee ; Despang, Alexandra ; Dickel, Diane E. ; Duran, Madeleine ; Feuchtinger, Annette ; Fuchs, Helmut ; Gailus-Durner, Valerie ; Haag, Natja ; Hägerling, Rene ; Hansmeier, Nils ; Hennig, Friederike ; Marshall, Cooper ; Rajderkar, Sudha ; Ringel, Alessa ; Robson, Michael ; Saunders, Lauren M. ; da Silva-Buttkus, Patricia ; Spielmann, Nadine ; Srivatsan, Sanjay R. ; Ulferts, Sascha ; Wittler, Lars ; Zhu, Yiwen ; Kalscheuer, Vera M. ; Ibrahim, Daniel M. ; Kurth, Ingo ; Kornak, Uwe ; Visel, Axel ; Pennacchio, Len A. ; Beier, David R. ; Trapnell, Cole ; Cao, Junyue ; Shendure, Jay ; Spielmann, Malte
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-11, Vol.623 (7988), p.772-781
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ArticlesPeer ReviewedFull Text
Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans
Author / Creator:Abe, Koichiro ; Cox, Allison ; Takamatsu, Nobuhiko ; Velez, Gabriel ; Laxer, Ronald M. ; Tse, Shirley M. L. ; Mahajan, Vinit B. ; Bassuk, Alexander G. ; Fuchs, Helmut ; Ferguson, Polly J. ; de Angelis, Martin Hrabe
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (24), p.11872-11877
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Epigenetic germline inheritance of diet-induced obesity and insulin resistance
Author / Creator:Huypens, Peter ; Sass, Steffen ; Wu, Moya ; Dyckhoff, Daniela ; Tschöp, Matthias ; Theis, Fabian ; Marschall, Susan ; de Angelis, Martin Hrabě ; Beckers, Johannes
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2016-05, Vol.48 (5), p.497-499
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Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
Author / Creator:Jacobsen, Henning ; Walendy-Gnirß, Kerstin ; Tekin-Bubenheim, Nilgün ; Kouassi, Nancy Mounogou ; Ben-Batalla, Isabel ; Berenbrok, Nikolaus ; Wolff, Martin ; dos Reis, Vinicius Pinho ; Zickler, Martin ; Scholl, Lucas ; Gries, Annette ; Jania, Hanna ; Kloetgen, Andreas ; Düsedau, Arne ; Pilnitz-Stolze, Gundula ; Jeridi, Aicha ; Yildirim, Ali Önder ; Fuchs, Helmut ; Gailus-Durner, Valerie ; Stoeger, Claudia ; de Angelis, Martin Hrabe ; Manuylova, Tatjana ; Klingel, Karin ; Culley, Fiona J. ; Behrends, Jochen ; Loges, Sonja ; Schneider, Bianca ; Krauss-Etschmann, Susanne ; Openshaw, Peter ; Gabriel, Gülsah
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.4957-4957, Article 4957
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Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
Author / Creator:Floegel, Anna ; Stefan, Norbert ; Yu, Zhonghao ; Mühlenbruch, Kristin ; Drogan, Dagmar ; Joost, Hans-Georg ; Fritsche, Andreas ; Häring, Hans-Ulrich ; Hrabě de Angelis, Martin ; Peters, Annette ; Roden, Michael ; Prehn, Cornelia ; Wang-Sattler, Rui ; Illig, Thomas ; Schulze, Matthias B. ; Adamski, Jerzy ; Boeing, Heiner ; Pischon, Tobias
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-02, Vol.62 (2), p.639-648
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eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
Author / Creator:Brina, Daniela ; Miluzio, Annarita ; Ricciardi, Sara ; Clarke, Kim ; Davidsen, Peter K. ; Viero, Gabriella ; Tebaldi, Toma ; Offenhäuser, Nina ; Rozman, Jan ; Rathkolb, Birgit ; Neschen, Susanne ; Klingenspor, Martin ; Wolf, Eckhard ; Gailus-Durner, Valerie ; Fuchs, Helmut ; Hrabe de Angelis, Martin ; Quattrone, Alessandro ; Falciani, Francesco ; Biffo, Stefano
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-09, Vol.6 (1), p.8261-8261, Article 8261
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Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy
Author / Creator:Rajendran, Jayasimman ; Purhonen, Janne ; Tegelberg, Saara ; Smolander, Olli‐Pekka ; Mörgelin, Matthias ; Rozman, Jan ; Gailus‐Durner, Valerie ; Fuchs, Helmut ; Hrabe de Angelis, Martin ; Auvinen, Petri ; Mervaala, Eero ; Jacobs, Howard T ; Szibor, Marten ; Fellman, Vineta ; Kallijärvi, Jukka
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2019-01, Vol.11 (1), p.1-n/a
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Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue
Author / Creator:Becker, Lore ; Nogueira, Melanie Schmitt ; Klima, Caroline ; de Angelis, Martin Hrabe ; Peleg, Shahaf
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-03, Vol.8 (1), p.4199-7, Article 4199
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Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice
Author / Creator:Keipert, Susanne ; Lutter, Dominik ; Schroeder, Bjoern O. ; Brandt, Daniel ; Ståhlman, Marcus ; Schwarzmayr, Thomas ; Graf, Elisabeth ; Fuchs, Helmut ; de Angelis, Martin Hrabe ; Tschöp, Matthias H. ; Rozman, Jan ; Jastroch, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1804-1, Article 1804
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How connecting data may lead to discoveries in medical research: Dr Alexander Jarasch and Professor Martin Hrabe de Angelis explain that novel research methods produce tremendous amounts of data that...
Author / Creator:Jarasch, Alexander ; de Angelis, Martin Hrabe
Publisher:Europa Science, Ltd
Journal title:Scientific computing world, 2018-08 (161), p.24
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Fibroblast Growth Factor 21—Metabolic Role in Mice and Men

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Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo

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Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

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Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach

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Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification

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Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

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Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ

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TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity

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Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

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Single-cell, whole-embryo phenotyping of mammalian developmental disorders

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Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans

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Epigenetic germline inheritance of diet-induced obesity and insulin resistance

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Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

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Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

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eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

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Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy

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Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue

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Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

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How connecting data may lead to discoveries in medical research: Dr Alexander Jarasch and Professor Martin Hrabe de Angelis explain that novel research methods produce tremendous amounts of data that...

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