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966 results for Peptide+Synthases

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ArticlesPeer ReviewedFull Text
Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering
Author / Creator:Nielsen, Maria Lund ; Isbrandt, Thomas ; Petersen, Lene Maj ; Mortensen, Uffe Hasbro ; Andersen, Mikael Rørdam ; Hoof, Jakob Blæsbjerg ; Larsen, Thomas Ostenfeld
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-08, Vol.11 (8), p.e0161199-e0161199
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Non-ribosomal Peptide Synthases from Pseudomonas aeruginosa Play a Role in Cyclodipeptide Biosynthesis, Quorum-Sensing Regulation, and Root Development in a Plant Host
Author / Creator:Gonzalez, Omar ; Ortiz-Castro, Randy ; Diaz-Perez, Cesar ; Diaz-Perez, Alma L ; Magana-Duenas, Viridiana ; Lopez-Bucio, Jose ; Campos-Garcia, Jesus
Publisher:New York: Springer Science + Business Media
Journal title:Microbial ecology, 2017-04, Vol.73 (3), p.616-629
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De novo design and engineering of non-ribosomal peptide synthetases
Author / Creator:Bozhüyük, Kenan A. J. ; Fleischhacker, Florian ; Linck, Annabell ; Wesche, Frank ; Tietze, Andreas ; Niesert, Claus-Peter ; Bode, Helge B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2018-03, Vol.10 (3), p.275-281
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Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains
Author / Creator:Bozhüyük, Kenan A. J. ; Linck, Annabell ; Tietze, Andreas ; Kranz, Janik ; Wesche, Frank ; Nowak, Sarah ; Fleischhacker, Florian ; Shi, Yan-Ni ; Grün, Peter ; Bode, Helge B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2019-07, Vol.11 (7), p.653-661
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In-Situ Purification of Non-Ribosomal Peptide Synthetases Assembly Line for Structural and Biochemical Studies
Author / Creator:Cao, Wei ; Chen, Shyue Leh ; Wu, Suen Kit ; Wang, Jialiang ; Deng, Zixin ; Liang, Jingdan ; Wang, Zhijun
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-02, Vol.26 (4), p.1750
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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Author / Creator:Awakawa, Takayoshi ; Fujioka, Takuma ; Zhang, Lihan ; Hoshino, Shotaro ; Hu, Zhijuan ; Hashimoto, Junko ; Kozone, Ikuko ; Ikeda, Haruo ; Shin-Ya, Kazuo ; Liu, Wen ; Abe, Ikuro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3534-10, Article 3534
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The structural biology of biosynthetic megaenzymes
Author / Creator:Weissman, Kira J
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2015-09, Vol.11 (9), p.660-670
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Gene editing enables rapid engineering of complex antibiotic assembly lines
Author / Creator:Thong, Wei Li ; Zhang, Yingxin ; Zhuo, Ying ; Robins, Katherine J. ; Fyans, Joanna K. ; Herbert, Abigail J. ; Law, Brian J. C. ; Micklefield, Jason
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6872-6872, Article 6872
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Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
Author / Creator:Mendes, Vitor ; Green, Simon R. ; Evans, Joanna C. ; Hess, Jeannine ; Blaszczyk, Michal ; Spry, Christina ; Bryant, Owain ; Cory-Wright, James ; Chan, Daniel S-H. ; Torres, Pedro H. M. ; Wang, Zhe ; Nahiyaan, Navid ; O’Neill, Sandra ; Damerow, Sebastian ; Post, John ; Bayliss, Tracy ; Lynch, Sasha L. ; Coyne, Anthony G. ; Ray, Peter C. ; Abell, Chris ; Rhee, Kyu Y. ; Boshoff, Helena I. M. ; Barry, Clifton E. ; Mizrahi, Valerie ; Wyatt, Paul G. ; Blundell, Tom L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.143-143, Article 143
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Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme
Author / Creator:Yun, Choong-Soo ; Motoyama, Takayuki ; Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-10, Vol.6 (1), p.8758-8758, Article 8758
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Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
Author / Creator:Yao, Tingting ; Liu, Jing ; Liu, Zengzhi ; Li, Tong ; Li, Huayue ; Che, Qian ; Zhu, Tianjiao ; Li, Dehai ; Gu, Qianqun ; Li, Wenli
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4091-12, Article 4091
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ArticlesPeer ReviewedFull Text
Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes
Author / Creator:Robison, Patrick ; Caporizzo, Matthew A. ; Ahmadzadeh, Hossein ; Bogush, Alexey I. ; Chen, Christina Yingxian ; Margulies, Kenneth B. ; Shenoy, Vivek B. ; Prosser, Benjamin L.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6284), p.428-428
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Knowledge-guided data mining on the standardized architecture of NRPS: Subtypes, novel motifs, and sequence entanglements
Author / Creator:He, Ruolin ; Zhang, Jinyu ; Shao, Yuanzhe ; Gu, Shaohua ; Song, Chen ; Qian, Long ; Yin, Wen-Bing ; Li, Zhiyuan
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2023-05, Vol.19 (5), p.e1011100-e1011100
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A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells
Author / Creator:Nie, Jinglei ; Zhang, Xinyi ; Hu, Zhijuan ; Wang, Wei ; Schroer, Martin A. ; Ren, Jie ; Svergun, Dmitri ; Chen, Anyang ; Yang, Peiguo ; Zeng, An-Ping
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2449-12, Article 2449
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Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria
Author / Creator:Harris, Nicholas C. ; Sato, Michio ; Herman, Nicolaus A. ; Twigg, Frederick ; Cai, Wenlong ; Liu, Joyce ; Zhu, Xuejun ; Downey, Jordan ; Khalaf, Ryan ; Martin, Joelle ; Koshino, Hiroyuki ; Zhang, Wenjun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.7025-7030
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Molecular basis for azetidine-2-carboxylic acid biosynthesis
Author / Creator:Klaubert, Tim J. ; Gellner, Jonas ; Bernard, Charles ; Effert, Juliana ; Lombard, Carine ; Kaila, Ville R. I. ; Bode, Helge B. ; Li, Yanyan ; Groll, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1348-12, Article 1348
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Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis
Author / Creator:Alonzo, Diego A. ; Chiche-Lapierre, Clarisse ; Tarry, Michael J. ; Wang, Jimin ; Schmeing, T. Martin
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2020-05, Vol.16 (5), p.493-496
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Efficient nonenzymatic cyclization and domain shuffling drive pyrrolopyrazine diversity from truncated variants of a fungal NRPS
Author / Creator:Berry, Daniel ; Mace, Wade ; Grage, Katrin ; Wesche, Frank ; Gore, Sagar ; Schardl, Christopher L. ; Young, Carolyn A. ; Dijkwel, Paul P. ; Leuchtmann, Adrian ; Bode, Helge B. ; Scott, Barry
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (51), p.25614-25623
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Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module
Author / Creator:Fortinez, Camille Marie ; Bloudoff, Kristjan ; Harrigan, Connor ; Sharon, Itai ; Strauss, Mike ; Schmeing, T. Martin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.548-548, Article 548
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Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy
Author / Creator:Bodine, Sue C. ; Latres, Esther ; Baumhueter, Susanne ; Venus K.-M. Lai ; Nunez, Lorna ; Clarke, Brian A. ; Poueymirou, William T. ; Panaro, Frank J. ; Na, Erqian ; Dharmarajan, Kumar ; Pan, Zhen-Qiang ; Valenzuela, David M. ; DeChiara, Thomas M. ; Stitt, Trevor N. ; Yancopoulos, George D. ; Glass, David J.
Publisher:Washington, DC: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2001-11, Vol.294 (5547), p.1704-1708
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Showing 1 to 20 of 966 results

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Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering

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Non-ribosomal Peptide Synthases from Pseudomonas aeruginosa Play a Role in Cyclodipeptide Biosynthesis, Quorum-Sensing Regulation, and Root Development in a Plant Host

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De novo design and engineering of non-ribosomal peptide synthetases

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Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains

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In-Situ Purification of Non-Ribosomal Peptide Synthetases Assembly Line for Structural and Biochemical Studies

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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

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The structural biology of biosynthetic megaenzymes

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Gene editing enables rapid engineering of complex antibiotic assembly lines

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Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

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Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

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Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

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Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes

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Knowledge-guided data mining on the standardized architecture of NRPS: Subtypes, novel motifs, and sequence entanglements

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A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells

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Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria

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Molecular basis for azetidine-2-carboxylic acid biosynthesis

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Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis

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Efficient nonenzymatic cyclization and domain shuffling drive pyrrolopyrazine diversity from truncated variants of a fungal NRPS

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Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module

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Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

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