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212 results for Peroxidase+-+antagonists+

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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
Author / Creator:Mao, Chao ; Liu, Xiaoguang ; Zhang, Yilei ; Lei, Guang ; Yan, Yuelong ; Lee, Hyemin ; Koppula, Pranavi ; Wu, Shiqi ; Zhuang, Li ; Fang, Bingliang ; Poyurovsky, Masha V. ; Olszewski, Kellen ; Gan, Boyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-05, Vol.593 (7860), p.586-590
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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Author / Creator:Hangauer, Matthew J. ; Viswanathan, Vasanthi S. ; Ryan, Matthew J. ; Bole, Dhruv ; Eaton, John K. ; Matov, Alexandre ; Galeas, Jacqueline ; Dhruv, Harshil D. ; Berens, Michael E. ; Schreiber, Stuart L. ; McCormick, Frank ; McManus, Michael T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-11, Vol.551 (7679), p.247-250
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Molecular mechanisms of ferroptosis and its role in cancer therapy
Author / Creator:Xu, Tao ; Ding, Wei ; Ji, Xiaoyu ; Ao, Xiang ; Liu, Ying ; Yu, Wanpeng ; Wang, Jianxun
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2019-08, Vol.23 (8), p.4900-4912
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ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway
Author / Creator:Chu, Bo ; Kon, Ning ; Chen, Delin ; Li, Tongyuan ; Liu, Tong ; Jiang, Le ; Song, Shujuan ; Tavana, Omid ; Gu, Wei
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2019-05, Vol.21 (5), p.579-591
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Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
Author / Creator:Soula, Mariluz ; Weber, Ross A. ; Zilka, Omkar ; Alwaseem, Hanan ; La, Konnor ; Yen, Frederick ; Molina, Henrik ; Garcia-Bermudez, Javier ; Pratt, Derek A. ; Birsoy, Kıvanç
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2020-12, Vol.16 (12), p.1351-1360
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Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles
Author / Creator:Eaton, John K. ; Furst, Laura ; Ruberto, Richard A. ; Moosmayer, Dieter ; Hilpmann, André ; Ryan, Matthew J. ; Zimmermann, Katja ; Cai, Luke L. ; Niehues, Michael ; Badock, Volker ; Kramm, Anneke ; Chen, Sixun ; Hillig, Roman C. ; Clemons, Paul A. ; Gradl, Stefan ; Montagnon, Claire ; Lazarski, Kiel E. ; Christian, Sven ; Bajrami, Besnik ; Neuhaus, Roland ; Eheim, Ashley L. ; Viswanathan, Vasanthi S. ; Schreiber, Stuart L.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2020-05, Vol.16 (5), p.497-506
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RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma
Author / Creator:Li, Shengbiao ; He, Yuping ; Chen, Kexin ; Sun, Jiaojiao ; Zhang, Lulu ; He, Yaxin ; Yu, Hong ; Li, Qiuhong
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.2915019-2915019
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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury
Author / Creator:Tonnus, Wulf ; Meyer, Claudia ; Steinebach, Christian ; Belavgeni, Alexia ; von Mässenhausen, Anne ; Gonzalez, Nadia Zamora ; Maremonti, Francesca ; Gembardt, Florian ; Himmerkus, Nina ; Latk, Markus ; Locke, Sophie ; Marschner, Julian ; Li, Wenjun ; Short, Spencer ; Doll, Sebastian ; Ingold, Irina ; Proneth, Bettina ; Daniel, Christoph ; Kabgani, Nazanin ; Kramann, Rafael ; Motika, Stephen ; Hergenrother, Paul J. ; Bornstein, Stefan R. ; Hugo, Christian ; Becker, Jan Ulrich ; Amann, Kerstin ; Anders, Hans-Joachim ; Kreisel, Daniel ; Pratt, Derek ; Gütschow, Michael ; Conrad, Marcus ; Linkermann, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4402-14, Article 4402
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Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities
Author / Creator:Lubos, Edith ; Loscalzo, Joseph ; Handy, Diane E.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Antioxidants & redox signaling, 2011-10, Vol.15 (7), p.1957-1997
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TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cells
Author / Creator:Kim, Do Hyung ; Kim, Won Dong ; Kim, Sang Kyum ; Moon, Dae Hyuk ; Lee, Seung Jin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-05, Vol.11 (5), p.406, Article 406
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ArticlesPeer ReviewedFull Text
Immune evasion by a staphylococcal inhibitor of myeloperoxidase
Author / Creator:deJong, Nienke W. M. ; Ramyar, Kasra X. ; Guerra, Fermin E. ; Nijland, Reindert ; Fevre, Cindy ; Voyich, Jovanka M. ; McCarthy, Alex J. ; Garcia, Brandon L. ; van Kessel, Kok P. M. ; van Strijp, Jos A. G. ; Geisbrecht, Brian V. ; Haas, Pieter-Jan A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (35), p.9439-9444
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Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites
Author / Creator:Rochael, Natalia C. ; Guimarães-Costa, Anderson B. ; Nascimento, Michelle T. C. ; DeSouza-Vieira, Thiago S. ; Oliveira, Matheus P. ; Garcia e Souza, Luiz F. ; Oliveira, Marcus F. ; Saraiva, Elvira M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-12, Vol.5 (1), p.18302-18302, Article 18302
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The Ustilago maydis Effector Pep1 Suppresses Plant Immunity by Inhibition of Host Peroxidase Activity
Author / Creator:Hemetsberger, Christoph ; Herrberger, Christian ; Zechmann, Bernd ; Hillmer, Morten ; Doehlemann, Gunther
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2012-05, Vol.8 (5), p.e1002684
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Liver stage malaria infection is controlled by host regulators of lipid peroxidation
Author / Creator:Kain, Heather S. ; Glennon, Elizabeth K. K. ; Vijayan, Kamalakannan ; Arang, Nadia ; Douglass, Alyse N. ; Fortin, Chelsea L. ; Zuck, Meghan ; Lewis, Adam J. ; Whiteside, Samantha L. ; Dudgeon, Denali R. ; Johnson, Jarrod S. ; Aderem, Alan ; Stevens, Kelly R. ; Kaushansky, Alexis
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-01, Vol.27 (1), p.44-54
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Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy
Author / Creator:Kahn-Kirby, Amanda H. ; Amagata, Akiko ; Maeder, Celine I. ; Mei, Janet J. ; Sideris, Steve ; Kosaka, Yuko ; Hinman, Andrew ; Malone, Stephanie A. ; Bruegger, Joel J. ; Wang, Leslie ; Kim, Virna ; Shrader, William D. ; Hoff, Kevin G. ; Latham, Joey C. ; Ashley, Euan A. ; Wheeler, Matthew T. ; Bertini, Enrico ; Carrozzo, Rosalba ; Martinelli, Diego ; Dionisi-Vici, Carlo ; Chapman, Kimberly A. ; Enns, Gregory M. ; Gahl, William ; Wolfe, Lynne ; Saneto, Russell P. ; Johnson, Simon C. ; Trimmer, Jeffrey K. ; Klein, Matthew B. ; Holst, Charles R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-03, Vol.14 (3), p.e0214250
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ArticlesPeer ReviewedFull Text
Chitosan nanoparticles having higher degree of acetylation induce resistance against pearl millet downy mildew through nitric oxide generation
Author / Creator:Siddaiah, Chandra Nayaka ; Prasanth, Keelara Veerappa Harish ; Satyanarayana, Niranjan Raj ; Mudili, Venkataramana ; Gupta, Vijai Kumar ; Kalagatur, Naveen Kumar ; Satyavati, Tara ; Dai, Xiao-Feng ; Chen, Jie-Yin ; Mocan, Andrei ; Singh, Bhim Pratap ; Srivastava, Rakesh Kumar
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.2485-14, Article 2485
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Gut Microbiota Conversion of Dietary Ellagic Acid into Bioactive Phytoceutical Urolithin A Inhibits Heme Peroxidases
Author / Creator:Saha, Piu ; Yeoh, Beng San ; Singh, Rajbir ; Chandrasekar, Bhargavi ; Vemula, Praveen Kumar ; Haribabu, Bodduluri ; Vijay-Kumar, Matam ; Jala, Venkatakrishna R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0156811-e0156811
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APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy
Author / Creator:Du, Yu ; Zhou, Yu ; Yan, Xinyu ; Pan, Feiyan ; He, Lingfeng ; Guo, Zhigang ; Hu, Zhigang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2024-04, Vol.31 (4), p.431-446
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Advantages of an Electrochemical Method Compared to the Spectrophotometric Kinetic Study of Peroxidase Inhibition by Boroxine Derivative
Author / Creator:Ostojić, Jelena ; Herenda, Safija ; Bešić, Zerina ; Miloš, Mladen ; Galić, Borivoj
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2017-07, Vol.22 (7), p.1120
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Targeting vascular adhesion protein-1 and myeloperoxidase with a dual inhibitor SNT-8370 in preclinical models of inflammatory disease
Author / Creator:Glaros, Elias ; Foot, Jonathan ; Rayner, Ben ; Schilter, Heidi ; Zhang, Yunjia ; Paumann-Page, Martina ; Teixeira, Mauro M. ; Jarolimek, Wolfgang ; Thomas, Shane R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-04, Vol.16 (1), p.3430-18, Article 3430
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Showing 1 to 20 of 212 results

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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

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Molecular mechanisms of ferroptosis and its role in cancer therapy

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ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

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Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

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Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

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RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma

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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

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Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

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TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cells

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Immune evasion by a staphylococcal inhibitor of myeloperoxidase

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Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites

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The Ustilago maydis Effector Pep1 Suppresses Plant Immunity by Inhibition of Host Peroxidase Activity

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Liver stage malaria infection is controlled by host regulators of lipid peroxidation

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Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

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Chitosan nanoparticles having higher degree of acetylation induce resistance against pearl millet downy mildew through nitric oxide generation

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Gut Microbiota Conversion of Dietary Ellagic Acid into Bioactive Phytoceutical Urolithin A Inhibits Heme Peroxidases

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APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy

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Advantages of an Electrochemical Method Compared to the Spectrophotometric Kinetic Study of Peroxidase Inhibition by Boroxine Derivative

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Targeting vascular adhesion protein-1 and myeloperoxidase with a dual inhibitor SNT-8370 in preclinical models of inflammatory disease

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