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121 results for Talin+-+genetics

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ArticlesPeer ReviewedFull Text
Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development
Author / Creator:Amezquita, Jonathan ; Desbois, Muriel ; Opperman, Karla J. ; Pak, Joseph S. ; Christensen, Elyse L. ; Nguyen, Nikki T. ; Diaz-Garcia, Karen ; Borgen, Melissa A. ; Grill, Brock
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2024-12, Vol.20 (12), p.e1011496
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The mechanical response of talin
Author / Creator:Yao, Mingxi ; Goult, Benjamin T. ; Klapholz, Benjamin ; Hu, Xian ; Toseland, Christopher P. ; Guo, Yingjian ; Cong, Peiwen ; Sheetz, Michael P. ; Yan, Jie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-07, Vol.7 (1), p.11966-11966, Article 11966
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The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
Author / Creator:Owen, Leanna M. ; Bax, Nicolas A. ; Weis, William I. ; Dunn, Alexander R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (10), p.1-7
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Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions
Author / Creator:Case, Lindsay B. ; Baird, Michelle A. ; Shtengel, Gleb ; Campbell, Sharon L. ; Hess, Harald F. ; Davidson, Michael W. ; Waterman, Clare M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-07, Vol.17 (7), p.880-892
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Extracellular rigidity sensing by talin isoform-specific mechanical linkages
Author / Creator:Austen, Katharina ; Ringer, Pia ; Mehlich, Alexander ; Chrostek-Grashoff, Anna ; Kluger, Carleen ; Klingner, Christoph ; Sabass, Benedikt ; Zent, Roy ; Rief, Matthias ; Grashoff, Carsten
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-12, Vol.17 (12), p.1597-1606
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Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second
Author / Creator:Strohmeyer, Nico ; Bharadwaj, Mitasha ; Costell, Mercedes ; Fässler, Reinhard ; Müller, Daniel J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature materials, 2017-12, Vol.16 (12), p.1262-1270
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Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity
Author / Creator:Wu, Jiaxi ; Wu, Huaizhu ; An, Jinping ; Ballantyne, Christie M. ; Cyster, Jason G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.6786-6791
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The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening
Author / Creator:Andreu, Ion ; Falcones, Bryan ; Hurst, Sebastian ; Chahare, Nimesh ; Quiroga, Xarxa ; Le Roux, Anabel-Lise ; Kechagia, Zanetta ; Beedle, Amy E. M. ; Elosegui-Artola, Alberto ; Trepat, Xavier ; Farré, Ramon ; Betz, Timo ; Almendros, Isaac ; Roca-Cusachs, Pere
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4229-4229, Article 4229
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Vinculin controls talin engagement with the actomyosin machinery
Author / Creator:Atherton, Paul ; Stutchbury, Ben ; Wang, De-Yao ; Jethwa, Devina ; Tsang, Ricky ; Meiler-Rodriguez, Eugenia ; Wang, Pengbo ; Bate, Neil ; Zent, Roy ; Barsukov, Igor L. ; Goult, Benjamin T. ; Critchley, David R. ; Ballestrem, Christoph
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-12, Vol.6 (1), p.10038-10038, Article 10038
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Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair
Author / Creator:Zhou, Dennis W. ; Fernández-Yagüe, Marc A. ; Holland, Elijah N. ; García, Andrés F. ; Castro, Nicolas S. ; O’Neill, Eric B. ; Eyckmans, Jeroen ; Chen, Christopher S. ; Fu, Jianping ; Schlaepfer, David D. ; García, Andrés J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-04, Vol.12 (1), p.2359-2359, Article 2359
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The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation
Author / Creator:Chinthalapudi, Krishna ; Rangarajan, Erumbi S. ; Izard, Tina
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (41), p.10339-10344
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Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction
Author / Creator:Roca-Cusachs, Pere ; Gauthier, Nils C ; Del Rio, Armando ; Sheetz, Michael P
Publisher:United States
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16245-16250
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Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy
Author / Creator:Manso, Ana Maria ; Okada, Hideshi ; Sakamoto, Francesca M. ; Moreno, Emily ; Monkley, Susan J. ; Li, Ruixia ; Critchley, David R. ; Ross, Robert S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (30), p.E6250-E6259
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Talin and vinculin combine their activities to trigger actin assembly
Author / Creator:Wang, Hong ; Said, Rayan ; Nguyen-Vigouroux, Clémence ; Henriot, Véronique ; Gebhardt, Peter ; Pernier, Julien ; Grosse, Robert ; Le Clainche, Christophe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.9497-15, Article 9497
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Actin flow-dependent and -independent force transmission through integrins
Author / Creator:Driscoll, Tristan P. ; Ahn, Sang Joon ; Huang, Billy ; Kumar, Abhishek ; Schwartz, Martin A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (51), p.32413-32422
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Rear traction forces drive adherent tissue migration in vivo
Author / Creator:Yamaguchi Naoya ; Zhang Ziyi ; Schneider Teseo ; Wang, Biran ; Panozzo Daniele ; Knaut Holger
Publisher:London: Nature Publishing Group
Journal title:Nature cell biology, 2022-02, Vol.24 (2), p.194-204
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Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding
Author / Creator:Zhang, Pingfeng ; Azizi, Latifeh ; Kukkurainen, Sampo ; Gao, Tong ; Baikoghli, Mo ; Jacquier, Marie-Claude ; Sun, Yijuan ; Määttä, Juha A. E. ; Cheng, R. Holland ; Wehrle-Haller, Bernhard ; Hytönen, Vesa P. ; Wu, Jinhua
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (51), p.32402-32412
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Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation
Author / Creator:Zhu, Liang ; Yang, Jun ; Bromberger, Thomas ; Holly, Ashley ; Lu, Fan ; Liu, Huan ; Sun, Kevin ; Klapproth, Sarah ; Hirbawi, Jamila ; Byzova, Tatiana V. ; Plow, Edward F. ; Moser, Markus ; Qin, Jun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1744-12, Article 1744
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The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin
Author / Creator:Gunawan, Merry ; Venkatesan, Nandini ; Loh, Jia Tong ; Wong, Jong Fu ; Berger, Heidi ; Neo, Wen Hao ; Li, Liang Yao Jackson ; La Win, Myint Khun ; Yau, Yin Hoe ; Guo, Tiannan ; See, Peter Chi Ee ; Yamazaki, Sayuri ; Chin, Keh Chuang ; Gingras, Alexandre R ; Shochat, Susana Geifman ; Ng, Lai Guan ; Sze, Siu Kwan ; Ginhoux, Florent ; Su, I-hsin
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-05, Vol.16 (5), p.505-516
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Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome
Author / Creator:Park, Sun-Ji ; Kim, Yeawon ; Yang, Shyh-Ming ; Henderson, Mark J. ; Yang, Wei ; Lindahl, Maria ; Urano, Fumihiko ; Chen, Ying Maggie
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (28), p.14154-14163
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Showing 1 to 20 of 121 results

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Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development

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The mechanical response of talin

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The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin

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Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

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Extracellular rigidity sensing by talin isoform-specific mechanical linkages

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Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

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Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity

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The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

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Vinculin controls talin engagement with the actomyosin machinery

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Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

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The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation

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Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction

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Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy

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Talin and vinculin combine their activities to trigger actin assembly

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Actin flow-dependent and -independent force transmission through integrins

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Rear traction forces drive adherent tissue migration in vivo

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Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding

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Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation

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The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

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Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome

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